TRPC1 binds to caveolin-3 and is regulated by Src kinase – role in Duchenne muscular dystrophy

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Journal of Cell Science

• Publication date

  2008-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1242/jcs.032003PMID 18544631
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Caveolin Regulates Endocytosis of the Muscle Repair Protein, Dysferlin*

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• N‐Acetylcysteine ameliorates skeletal muscle pathophysiology in mdx mice

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• Dystrophic cardiomyopathy: amplification of cellular damage by Ca2+ signalling and reactive oxygen species-generating pathways.

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• Regulation of ubiquitin-proteasome system mediated degradation by cytosolic stress.

  2007cited by this paper
• Developmental increase in the amount of rapsyn per acetylcholine receptor promotes postsynaptic receptor packing and stability.

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• Revisiting TRPC1 and TRPC6 mechanosensitivity

  2007cited by this paper
• Store-Operated Ca2+ Influx and Expression of TRPC Genes in Mouse Sinoatrial Node

  2007cited by this paper
• TRP channels.

  2007cited by this paper
• The role of reactive oxygen species in the hearts of dystrophin-deficient mdx mice.

  2007cited by this paper
• Intracellular calcium handling in ventricular myocytes from mdx mice.

  2007cited by this paper
• Regulation of capacitative calcium entries by α1‐syntrophin: association of TRPC1 with dystrophin complex and the PDZ domain of α1‐syntrophin

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• Genetic Evidence Supporting Caveolae Microdomain Regulation of Calcium Entry in Endothelial Cells*

  2007cited by this paper
• Pressure-induced and store-operated cation influx in vascular smooth muscle cells is independent of TRPC1

  2007cited by this paper
• Regulation of capacitative calcium entries by alpha1-syntrophin: association of TRPC1 with dystrophin complex and the PDZ domain of alpha1-syntrophin.

  2007cited by this paper
• TRPC3 and TRPC4 Associate to Form a Redox-sensitive Cation Channel

  2006cited by this paper
• Linkage between cellular communications, energy utilization, and proliferation in metastatic neuroendocrine cancers

  2006cited by this paper
• Molecular Rearrangements of the Kv2.1 Potassium Channel Termini Associated with Voltage Gating*

  2006cited by this paper
• Expression of canonical transient receptor potential (TRPC) proteins in human glomerular mesangial cells.

  2006cited by this paper
• Role of Src in C3 transient receptor potential channel function and evidence for a heterogeneous makeup of receptor- and store-operated Ca2+ entry channels.

  2006influential reference
• TRPC1 functions as a store-operated Ca2+ channel in intestinal epithelial cells and regulates early mucosal restitution after wounding.

  2006cited by this paper
• Up-regulation of transient receptor potential canonical 1 (TRPC1) following sarco(endo)plasmic reticulum Ca2+ ATPase 2 gene silencing promotes cell survival: a potential role for TRPC1 in Darier's disease.

  2006cited by this paper
• Caveolin-1 Regulates Store-Operated Ca2+ Influx by Binding of Its Scaffolding Domain to Transient Receptor Potential Channel-1 in Endothelial Cells

  2006cited by this paper
• Streptomycin reduces stretch-induced membrane permeability in muscles from mdx mice.

  2006cited by this paper
• Functional role of store‐operated and stretch‐activated channels in murine adult skeletal muscle fibres

  2006cited by this paper
• Upregulated TRPC1 Channel in Vascular Injury In Vivo and Its Role in Human Neointimal Hyperplasia

  2006cited by this paper
• MUSCLE DAMAGE IN MDX (DYSTROPHIC) MICE: ROLE OF CALCIUM AND REACTIVE OXYGEN SPECIES

  2006cited by this paper
• STIM1 carboxyl-terminus activates native SOC, Icrac and TRPC1 channels

  2006cited by this paper
• Molecular Analysis of a Store-operated and 2-Acetyl-sn-glycerol-sensitive Non-selective Cation Channel

  2005cited by this paper
• Effects of stretch‐activated channel blockers on [Ca2+]i and muscle damage in the mdx mouse

  2005cited by this paper
• Endogenous TRPC 1 , TRPC 3 , and TRPC 7 Proteins Combine to Form Native Store-operated Channels in HEK-293 Cells *

  2005cited by this paper
• Tyrosine Phosphorylation of Caveolin 1 by Oxidative Stress Is Reversible and Dependent on the c-src Tyrosine Kinase but Not Mitogen-Activated Protein Kinase Pathways in Placental Artery Endothelial Cells1

  2005cited by this paper
• Endogenous TRPC1, TRPC3, and TRPC7 Proteins Combine to Form Native Store-operated Channels in HEK-293 Cells*

  2005cited by this paper
• TRPC1 forms the stretch-activated cation channel in vertebrate cells

  2005influential reference
• Increased ratio of rapsyn to ACh receptor stabilizes postsynaptic receptors at the mouse neuromuscular synapse

  2005cited by this paper
• Fluorescence lifetime imaging of coral fluorescent proteins

  2005influential reference
• Epidermal Growth Factor Induces Tyrosine Phosphorylation, Membrane Insertion, and Activation of Transient Receptor Potential Channel 4*

  2005cited by this paper
• Role of Src in C 3 transient receptor potential channel function and evidence for a heterogeneous makeup of receptor-and store-operated Ca 2 entry channels

  2005influential reference
• Regulation of TRPC6 Channel Activity by Tyrosine Phosphorylation*

  2004cited by this paper
• Obligatory Role of Src Kinase in the Signaling Mechanism for TRPC3 Cation Channels*

  2004cited by this paper
• A TRPC1/TRPC3-mediated Increase in Store-operated Calcium Entry Is Required for Differentiation of H19-7 Hippocampal Neuronal Cells*♦

  2004cited by this paper
• Protein Kinase Cα Phosphorylates the TRPC1 Channel and Regulates Store-operated Ca2+ Entry in Endothelial Cells*

  2004cited by this paper
• The Caveolin genes: from cell biology to medicine

  2004cited by this paper
• Two Types of Store-operated Ca2+ Channels with Different Activation Modes and Molecular Origin in LNCaP Human Prostate Cancer Epithelial Cells*

  2004cited by this paper
• Dynamic and regulated association of caveolin with lipid bodies: modulation of lipid body motility and function by a dominant negative mutant.

  2003cited by this paper
• Aquaporin 3 colocates with phospholipase d2 in caveolin-rich membrane microdomains and is downregulated upon keratinocyte differentiation.

  2003cited by this paper
• Hydrogen peroxide stimulates c-Src-mediated big mitogen-activated protein kinase 1 (BMK1) and the MEF2C signaling pathway in PC12 cells : Potential role in cell survival following oxidative insults

  2003cited by this paper
• Caveolin-1 Contributes to Assembly of Store-operated Ca2+ Influx Channels by Regulating Plasma Membrane Localization of TRPC1*

  2003influential reference
• Hydrogen Peroxide Stimulates c-Src-mediated Big Mitogen-activated Protein Kinase 1 (BMK1) and the MEF2C Signaling Pathway in PC12 Cells

  2002cited by this paper
• Role of capacitative Ca2+ entry in bronchial contraction and remodeling.

  2002cited by this paper
• Involvement of TRPC in the abnormal calcium influx observed in dystrophic (mdx) mouse skeletal muscle fibers

  2002influential reference
• Subunit composition of mammalian transient receptor potential channels in living cells

  2002influential reference
• c-Jun N-terminal Kinase Activation by Hydrogen Peroxide in Endothelial Cells Involves Src-dependent Epidermal Growth Factor Receptor Transactivation*

  2001cited by this paper
• Muscular degeneration in the absence of dystrophin is a calcium-dependent process.

  2001cited by this paper
• Hydrogen peroxide induces Src family tyrosine kinase‐dependent activation of Xenopus eggs

  2001cited by this paper
• Imaging protein-protein interactions using fluorescence resonance energy transfer microscopy.

  2001cited by this paper
• Src family tyrosine kinases and growth factor signaling.

  2000cited by this paper
• Evidence that the TRP-1 protein is unlikely to account for store-operated Ca2+ inflow in Xenopus laevis oocytes

  2000cited by this paper
• Transgenic overexpression of caveolin-3 in skeletal muscle fibers induces a Duchenne-like muscular dystrophy phenotype.

  2000cited by this paper
• Assembly of Trp1 in a Signaling Complex Associated with Caveolin-Scaffolding Lipid Raft Domains*

  2000influential reference
• Förster distances between green fluorescent protein pairs.

  2000influential reference
• Trp 1 , a Candidate Protein for the Store-operated Ca 2 1 Influx Mechanism in Salivary Gland Cells

  2000cited by this paper
• Trp1, a Candidate Protein for the Store-operated Ca2+Influx Mechanism in Salivary Gland Cells*

  2000influential reference
• Fluorescence lifetime imaging microscopy: spatial resolution of biochemical processes in the cell.

  1999cited by this paper
• Targeted Down-regulation of Caveolin-3 Is Sufficient to Inhibit Myotube Formation in Differentiating C2C12 Myoblasts

  1999cited by this paper
• Mutations in the caveolin-3 gene cause autosomal dominant limb-girdle muscular dystrophy

  1998cited by this paper
• Increased caveolin‐3 levels in mdx mouse muscles

  1998cited by this paper
• Functional expression of TrpC1: a human homologue of the Drosophila Trp channel.

  1998influential reference
• Molecular genetics of the caveolin gene family: implications for human cancers, diabetes, Alzheimer disease, and muscular dystrophy.

  1998cited by this paper
• Muscle cells from mdx mice have an increased susceptibility to oxidative stress.

  1998cited by this paper
• Cellular functions regulated by Src family kinases.

  1997cited by this paper
• Src tyrosine kinases, Galpha subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin. Caveolin binding negatively regulates the auto-activation of Src tyrosine kinases.

  1996cited by this paper
• Expression of Caveolin-3 in Skeletal, Cardiac, and Smooth Muscle Cells

  1996cited by this paper
• Src Tyrosine Kinases, Gα Subunits, and H-Ras Share a Common Membrane-anchored Scaffolding Protein, Caveolin

  1996cited by this paper
• Imaging the intracellular trafficking and state of the AB5 quaternary structure of cholera toxin.

  1996influential reference
• Molecular Cloning of Caveolin-3, a Novel Member of the Caveolin Gene Family Expressed Predominantly in Muscle (*)

  1996influential reference
• Calpains Are Activated in Necrotic Fibers from mdx Dystrophic Mice (*)

  1995cited by this paper
• Dystrophin: the protein product of the Duchenne muscular dystrophy locus.

  1987cited by this paper
• Stretch‐activated single ion channel currents in tissue‐cultured embryonic chick skeletal muscle.

  1984cited by this paper

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• Effects of aging on calcium channels in skeletal muscle

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• Ion Channel Regulation in Caveolae and Its Pathological Implications

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• Stem/progenitor cell-based therapy for Duchenne muscular dystrophy

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• Diapocynin treatment induces functional and structural improvements in an advanced disease state in the mdx5Cv mice.

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• Are Aminoglycoside Antibiotics TRPing Your Metabolic Switches?

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• Porcine transient receptor potential channel 1 (TRPC1) regulates muscle growth via the Wnt/β-catenin and Wnt/Ca2+ pathways.

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• Protein networking: nicotinic acetylcholine receptors and their protein–protein-associations

  2024cites this paper
• Reduced voltage-activated Ca2+ release flux in muscle fibers from a rat model of Duchenne dystrophy.

  2024cites this paper
• Low-Level Photobiomodulation Therapy Modulates H2O2 Production, TRPC-6, and PGC-1α Levels in the Dystrophic Muscle

  2023cites this paper
• Hypochlorous acid exposure impairs skeletal muscle function and Ca2+ signalling: implications for Duchenne muscular dystrophy pathology

  2023cites this paper
• Harmonizing Magnetic Mitohormetic Regenerative Strategies: Developmental Implications of a Calcium–Mitochondrial Axis Invoked by Magnetic Field Exposure

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• High‐intensity interval training in the form of isometric contraction improves fatigue resistance in dystrophin‐deficient muscle

  2023cites this paper
• Concurrent Optical- and Magnetic-Stimulation-Induced Changes on Wound Healing Parameters, Analyzed by Hyperspectral Imaging: An Exploratory Case Series

  2023cites this paper
• The Developmental Implications of Muscle-Targeted Magnetic Mitohormesis: A Human Health and Longevity Perspective

  2023cites this paper
• Eccentric contraction-induced strength loss in dystrophin-deficient muscle: Preparations, protocols, and mechanisms

  2023cites this paper
• Ion Channels of the Sarcolemma and Intracellular Organelles in Duchenne Muscular Dystrophy: A Role in the Dysregulation of Ion Homeostasis and a Possible Target for Therapy

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• Cross-talk between TRPC-1, mTOR, PGC-1α and PPARδ in the dystrophic muscle cells treated with tempol

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• Brief exposure to directionally-specific pulsed electromagnetic fields stimulates extracellular vesicle release and is antagonized by streptomycin: A potential regenerative medicine and food industry paradigm.

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• Multiple LEDT wavelengths modulate the Akt signaling pathways and attenuate pathological events in mdx dystrophic muscle cells

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• Inward Rectifier Potassium Channels: Membrane Lipid-Dependent Mechanosensitive Gates in Brain Vascular Cells

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• Function of the Porcine TRPC1 Gene in Myogenesis and Muscle Growth

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• Inwardly Rectifying Potassium Channels

  2021cites this paper
• TRPC3, but not TRPC1, as a good therapeutic target for standalone or complementary treatment of DMD

  2021cites this paper
• Alteration of STIM1/Orai1-Mediated SOCE in Skeletal Muscle: Impact in Genetic Muscle Diseases and Beyond

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• Lifespan Analysis of Dystrophic mdx Fast-Twitch Muscle Morphology and Its Impact on Contractile Function

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• Master Regulators of Muscle Atrophy: Role of Costamere Components

  2021cites this paper
• Prevention of Connexin43 remodeling protects against duchenne muscular dystrophy cardiomyopathy.

  2020cites this paper
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  2020cites this paper
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  2020cites this paper
• Directionalities of magnetic fields and topographic scaffolds synergise to enhance MSC chondrogenesis.

  2020cites this paper
• Location and function of transient receptor potential canonical channel 1 in ventricular myocytes.

  2020cites this paper
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  2019influential citation
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2018cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2016cites this paper
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  2015cites this paper
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  2015cites this paper
• Caveolae – mechanosensitive membrane invaginations linked to actin filaments

  2015cites this paper
• SERCA1 overexpression minimizes skeletal muscle damage in dystrophic mouse models.

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• NADPH oxidases—do they play a role in TRPC regulation under hypoxia?

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• Genetic evidence in the mouse solidifies the calcium hypothesis of myofiber death in muscular dystrophy

  2015cites this paper
• Individual and combinatory effects of voluntary wheel running and sActRIIB-Fc administration on redox-balance in mdx mice

  2015cites this paper
• The role of contraction in skeletal muscle development

  2015cites this paper
• TRP channels in reproductive (neuro)endocrinology.

  2014cites this paper
• Physiological functions and regulation of TRPC channels.

  2014cites this paper
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  2014cites this paper
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  2014cites this paper
• Dystrophin complex functions as a scaffold for signalling proteins.

  2014cites this paper
• Regulation of intracellular signaling and function by caveolin

  2014cites this paper
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  2014cites this paper
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  2014cites this paper
• Reactive Oxygen Species and Muscular Dystrophy 135

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