Radial Columns in Cortical Architecture: It Is the Composition That Counts

The function of any brain structure depends on its neuronal composition and on the pattern of its extrinsic and intrinsic excitatory and inhibitory synaptic connectivity. In this issue of Cerebral Cortex, 3 related papers provide the most comprehensive analysis to date of the cellular and synaptic relationships of a standard cortical column in the somatosensory cortex of the Wistar rat. It is hoped that understanding normal composition of this archetypical cortical column may help to explain its functional operations, expose subtle pathological changes that could cause abnormal sensory and cognitive functions, and provide insight into evolution of the cerebral cortex.

• Publication year

  2010

• Venue

  Cerebral Cortex

• Publication date

  2010-07-28

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1093/cercor/bhq127PMID 20667930PMCID 2936809
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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