Neurobiology of seizure predisposition in the genetically epilepsy-prone rat.

No abstract is available for this paper.

• Publication year

  1989

• Venue

  Epilepsy Research

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1016/0920-1211(89)90063-6PMID 2563686
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1986cited by this paper
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  1986cited by this paper
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  1986cited by this paper
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  1986cited by this paper
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