Antioxidant defense systems in skin

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Journal of Toxicology: Cutaneous and Ocular Toxicology

• Publication date

  2002-01-01

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1081/CUS-120004330
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Vitamin A uptake by human skin in vitro

  2004cited by this paper
• PUVA-induced erythema and changes in mechanoelectrical properties of skin. Inhibition by tocopherols

  2004influential reference
• Effect of Topical Antioxidants on UV-Induced Erythema Formation when Administered after Exposure

  1999cited by this paper
• Measurement of Antioxidants in Cutaneous Tissues

  1999cited by this paper
• Topical melatonin in combination with vitamins E and C protects skin from ultraviolet‐induced erythema: a human study in vivo

  1998cited by this paper
• Depletion of human stratum corneum vitamin E: an early and sensitive in vivo marker of UV induced photo-oxidation.

  1998cited by this paper
• Polymorphism in glutathione S-transferase loci as a risk factor for common cancers.

  1998cited by this paper
• Increased skin tumorigenesis in mice lacking pi class glutathione S-transferases.

  1998influential reference
• Macromolecular carbonyls in human stratum corneum: a biomarker for environmental oxidant exposure?

  1998cited by this paper
• Increased dermal carotenoid levels assessed by noninvasive reflection spectrophotometry correlate with serum levels in women ingesting Betatene.

  1998cited by this paper
• Topical application of α‐tocopherol modulates the antioxidant network and diminishes ultraviolet‐induced oxidative damage in murine skin

  1998cited by this paper
• UV-irradiation depletes antioxidants and causes oxidative damage in a model of human skin.

  1998cited by this paper
• Vitamin E supplementation and in vivo immune response in healthy elderly subjects. A randomized controlled trial.

  1997cited by this paper
• Protective effects of silymarin against photocarcinogenesis in a mouse skin model.

  1997cited by this paper
• Ozone-exposure depletes vitamin E and induces lipid peroxidation in murine stratum corneum.

  1997cited by this paper
• Inhibition of ultraviolet light induced skin carcinogenesis in SKH-1 mice by apigenin, a plant flavonoid.

  1997cited by this paper
• Microfluorometry using fluorescein diacetate reflects the integrity of the plasma membrane in UVA‐irradiated cultured skin fibroblasts

  1997cited by this paper
• Epidermal localization and protective effects of topically applied superoxide dismutase

  1997cited by this paper
• Cysteine Derivatives Protect Against UV‐lnduced Reactive Intermediates in Human Keratinocytes: The Role of Glutathione Synthesis

  1997cited by this paper
• α‐Tocopherol, an Inhibitor of Epidermal Lipid Peroxidation, Prevents Ultraviolet Radiation from Suppressing the Skin Immune System

  1997cited by this paper
• Modulation of Ultraviolet Light‐Induced Epidermal Damage: Beneficial Effects of Tocopherol

  1997cited by this paper
• Time course of changes in antioxidant enzymes in human skin fibroblasts after UVA irradiation.

  1997cited by this paper
• Inhibition of UVB induced DNA photodamage in mouse epidermis by topically applied alpha-tocopherol.

  1997influential reference
• The formation of competent barrier lipids in reconstructed human epidermis requires the presence of vitamin C.

  1997cited by this paper
• Ascorbate Differentially Regulates Elastin and Collagen Biosynthesis in Vascular Smooth Muscle Cells and Skin Fibroblasts by Pretranslational Mechanisms*

  1997cited by this paper
• Oxidative stress and in vivo chemiluminescence in mouse skin exposed to UVA radiation.

  1997cited by this paper
• UVB induced photooxidation of vitamin E.

  1997cited by this paper
• Immunohistochemical study of alpha, mu and pi class glutathione S transferase expression in malignant melanoma

  1997cited by this paper
• Deficiency of glutathione S-transferases T1 and M1 as heritable factors of increased cutaneous UV sensitivity.

  1997cited by this paper
• Suppression of UV-lnduced Erythema by Topical Treatment with Melatonin (N-Acetyl-5-Methoxytryptamine)

  1997cited by this paper
• Effects of topically applied antioxidants in experimentally provoked polymorphous light eruption.

  1997cited by this paper
• Tropospheric ozone: an emerging environmental stress to skin.

  1997cited by this paper
• Suppression of UV-induced erythema by topical treatment with melatonin (N-acetyl-5-methoxytryptamine). Influence of the application time point.

  1997cited by this paper
• In vivo exposure to ozone depletes vitamins C and E and induces lipid peroxidation in epidermal layers of murine skin.

  1997cited by this paper
• Ozone depletes tocopherols and tocotrienols topically applied to murine skin

  1997cited by this paper
• Topical or oral administration with an extract of Polypodium leucotomos prevents acute sunburn and psoralen‐induced phototoxic reactions as well as depletion of Langerhans cells in human skin

  1997cited by this paper
• Stability of vitamin C derivatives in solution and topical formulations.

  1997cited by this paper
• Interactions between Vitamin E Homologues and Ascorbate Free Radicals in Murine Skin Homogenates Irradiated with Ultraviolet Light

  1997cited by this paper
• Efficacy of topically applied tocopherols and tocotrienols in protection of murine skin from oxidative damage induced by UV-irradiation.

  1997cited by this paper
• Inhibitory effect of magnesium L-ascorbyl-2-phosphate (VC-PMG) on melanogenesis in vitro and in vivo.

  1996cited by this paper
• Protective Effect of Magnesium‐L‐Ascorbyl‐2 Phosphate Against Skin Damage Induced by UVB Irradiation

  1996cited by this paper
• Glutathione Isopropyl Ester Reduces UVB‐lnduced Skin Damage in Hairless Mice

  1996cited by this paper
• Prevention of photocarcinogenesis by topical administration of pure epigallocatechin gallate isolated from green tea.

  1996cited by this paper
• Disposition and metabolism of topically administered alpha-tocopherol acetate: a common ingredient of commercially available sunscreens and cosmetics.

  1996cited by this paper
• Lipid metabolite involvement in the activation of the human heme oxygenase-1 gene.

  1996cited by this paper
• Kinetic study of cutaneous and subcutaneous distribution following topical application of [7,8-14C]rac-alpha-lipoic acid onto hairless mice.

  1996cited by this paper
• Importance of the form of topical vitamin E for prevention of photocarcinogenesis.

  1996cited by this paper
• Plant defence systems and ozone.

  1996cited by this paper
• UVA‐induced oxidative damage in fibroblasts cultured in a 3‐dimensional collagen matrix

  1996cited by this paper
• Activation of transcription factor AP-2 mediates UVA radiation- and singlet oxygen-induced expression of the human intercellular adhesion molecule 1 gene.

  1996cited by this paper
• Effects of controlled exposure of sunlight on plasma and skin levels of beta-carotene.

  1996cited by this paper
• Inhibition of ultraviolet‐induced formation of reactive oxygen species, lipid peroxidation, erythema and skin photosensitization by Polypodium leucotomos

  1996cited by this paper
• Synergistic topical photoprotection by a combination of the iron chelator 2-furildioxime and sunscreen.

  1996cited by this paper
• Comparison of photosensitized plasma membrane damage caused by singlet oxygen and free radicals.

  1996cited by this paper
• EPR Detection of Free Radicals in UV‐lrradiated Skin: Mouse Versus Human

  1996cited by this paper
• Effectiveness of antioxidants (vitamin C and E) with and without sunscreens as topical photoprotectants.

  1996cited by this paper
• Vitamin E in humans: demand and delivery.

  1996influential reference
• UVA‐induced immune suppression in human skin: protective effect of vitamin E in human epidermal cells in vitro

  1996cited by this paper
• Ubiquinone-dependent recycling of vitamin E radicals by superoxide.

  1995influential reference
• Protective effect evaluation of free radical scavengers on UVB induced human cutaneous erythema by skin reflectance spectrophotometry

  1995cited by this paper
• PROTECTION AGAINST ULTRAVIOLET‐B RADIATION‐INDUCED LOCAL and SYSTEMIC SUPPRESSION OF CONTACT HYPERSENSITIVITY and EDEMA RESPONSES IN C3H/HeN MICE BY GREEN TEA POLYPHENOLS

  1995cited by this paper
• IMPACT OF UVB and 03 ON THE OXYGEN FREE RADICAL SCAVENGING SYSTEM IN Arabidopsis thaliana GENOTYPES DIFFERING IN FLAVONOID BIOSYNTHESIS

  1995cited by this paper
• A review of the evidence supporting melatonin's role as an antioxidant

  1995cited by this paper
• Hydrolysis of RRR-alpha-tocopheryl acetate (vitamin E acetate) in the skin and its UV protecting activity (an in vivo study with the rat).

  1995influential reference
• Possible role of 1,25-dihydroxyvitamin D3-induced metallothionein in photoprotection against UVB injury in mouse skin and cultured rat keratinocytes.

  1995cited by this paper
• UVA radiation-induced oxidative damage to lipids and proteins in vitro and in human skin fibroblasts is dependent on iron and singlet oxygen.

  1995cited by this paper
• Singlet Oxygen Generation from the Reaction of Ozone with Plant Leaves (*)

  1995cited by this paper
• UV radiation protecting efficacy of cysteine derivatives, studies with UVA-induced binding of 8-MOP and CPZ to rat epidermal biomacromolecules in vivo.

  1995influential reference
• Chronic UVB irradiation induces superoxide dismutase activity in human epidermis in vivo.

  1995cited by this paper
• Skin lycopene is destroyed preferentially over beta-carotene during ultraviolet irradiation in humans.

  1995cited by this paper
• Singlet oxygen may mediate the ultraviolet A-induced synthesis of interstitial collagenase.

  1995cited by this paper
• Effect of topically applied tocopherol on ultraviolet radiation-mediated free radical damage in skin.

  1995cited by this paper
• Enzymic and non-enzymic antioxidants in epidermis and dermis of human skin.

  1994cited by this paper
• The impact of UV-B radiation and ozone on terrestrial vegetation.

  1994cited by this paper
• Recovery of antioxidants and reduction in lipid hydroperoxides in murine epidermis and dermis after acute ultraviolet radiation exposure.

  1994cited by this paper
• Antioxidant inhibition of skin inflammation induced by reactive oxidants: evaluation of the redox couple dihydrolipoate/lipoate.

  1994cited by this paper
• Effect of age on antioxidants and molecular markers of oxidative damage in murine epidermis and dermis.

  1994cited by this paper
• The effect of N-acetylcysteine on the UVB-induced inhibition of epidermal DNA synthesis in rat skin.

  1994influential reference
• Oxyradical involvement in PUVA-induced skin reactions. Protection by local application of SOD

  1994cited by this paper
• Free radicals in cutaneous biology.

  1994cited by this paper
• Photooxidative stress in plants

  1994cited by this paper
• 4 – Nonenzymatic Antioxidant Defense Systems

  1994cited by this paper
• Evaluation of a topical iron chelator in animals and in human beings: short-term photoprotection by 2-furildioxime.

  1994cited by this paper
• UV-radiation protecting efficacy of thiols, studied with UVA-induced binding of 8-MOP and CPZ to rat epidermal biomacromolecules in vivo.

  1993influential reference
• Antioxidant defense mechanisms in murine epidermis and dermis and their responses to ultraviolet light.

  1993cited by this paper
• Autoxidation of lipids and antioxidation by alpha-tocopherol and ubiquinol in homogeneous solution and in aqueous dispersions of lipids: unrecognized consequences of lipid particle size as exemplified by oxidation of human low density lipoprotein.

  1993cited by this paper
• UPTAKE AND BIOCONVERSION OF α‐TOCOPHERYL ACETATE TO α‐TOCOPHEROL IN SKIN OF HAIRLESS MICE

  1993cited by this paper
• Thiols as potential UV radiation protectors: an in vitro study.

  1993cited by this paper
• Dose-response effects of acute ultraviolet irradiation on antioxidants and molecular markers of oxidation in murine epidermis and dermis.

  1993cited by this paper
• Topical application and uptake of vitamin E acetate by the skin and conversion to free vitamin E.

  1993cited by this paper
• Reduction of sunburn damage to skin by topical application of vitamin E acetate following exposure to ultraviolet B radiation: effect of delaying application or of reducing concentration of vitamin E acetate applied.

  1993cited by this paper
• EVIDENCE FOR THE PHOTOPROTECTIVE EFFECTS OF VITAMIN E

  1993cited by this paper
• Loss of alpha-tocopherol upon exposure to nitric oxide or the sydnonimine SIN-1.

  1993cited by this paper
• Strategies of antioxidant defense.

  1993cited by this paper
• Loss of α‐tocopherol upon exposure to nitric oxide or the sydnonimine SIN‐1

  1993cited by this paper
• Antioxidant Functions of Vitamins

  1992cited by this paper
• The effect of topical L-selenomethionine on minimal erythema dose of ultraviolet irradiation in humans.

  1992cited by this paper
• Topical tocopherol acetate reduces post-UVB, sunburn-associated erythema, edema, and skin sensitivity in hairless mice.

  1992cited by this paper
• Formation of 8-hydroxydeoxyguanosine within DNA of mouse keratinocytes exposed in culture to UVB and H2O2.

  1992cited by this paper
• Distribution and redox state of ubiquinones in rat and human tissues.

  1992cited by this paper

• The Impacts of Non-Surgical Aesthetics on the Core Functional Triad of Skin

  2025cites this paper
• Evaluation of Cannabis sativa L. Callus Extract as a Novel Cosmetic Ingredient with Dual Anti-Inflammatory and Antioxidant Effects

  2025cites this paper
• Kombucha as a Potential Active Ingredient in Cosmetics—An Ex Vivo Skin Permeation Study

  2024cites this paper
• Differential effects of benzo[a]pyrene exposure on glutathione and purine metabolism in keratinocytes: Dose‐dependent and UV co‐exposure effects

  2024cites this paper
• Safe and Effective Antioxidant: The Biological Mechanism and Potential Pathways of Ergothioneine in the Skin

  2023cites this paper
• Effect of Lumenato oral supplementation on plasma carotenoid levels and improvement of visual and experiential skin attributes

  2022cites this paper
• Targeting Hydroxybenzoic Acids to Mitochondria as a Strategy to Delay Skin Ageing: An In Vitro Approach

  2022cites this paper
• The Role of Natural Antioxidants in Reducing Oxidative Stress in Cancer

  2021cites this paper
• Application of Carotenoids in Cosmetics

  2021cites this paper
• Anti-ageing effects of Ubiquinone and Ubiquinol in a senescence model of human dermal fibroblasts.

  2021cites this paper
• Marine-Derived Compounds with Potential Use as Cosmeceuticals and Nutricosmetics

  2020cites this paper
• Dietary lutein supplementation protects against ultraviolet-radiation-induced erythema: Results of a randomized double-blind placebo-controlled study

  2020cites this paper
• Formulation development and accelerated stability testing of a novel sunscreen cream for ultraviolet radiation protection in high altitude areas

  2019cites this paper
• Amelioration of UV radiation‐induced photoaging by a combinational sunscreen formulation via aversion of oxidative collagen degradation and promotion of TGF‐&bgr;‐Smad‐mediated collagen production

  2019cites this paper
• Biofunctional Textiles

  2019cites this paper
• Mathematical models for drug delivery from textile

  2019cites this paper
• The role of diet in maintaining healthy skin

  2018cites this paper
• Lutein, a versatile phyto-nutraceutical: An insight on pharmacology, therapeutic indications, challenges and recent advances in drug delivery

  2017cites this paper
• Modulation of cutaneous scavenger receptor B1 levels by exogenous stressors impairs "in vitro" wound closure.

  2017cites this paper
• An overview on natural antioxidants for oxidative stress reduction in cancers; a systematic review

  2017cites this paper
• Kwas α-liponowy – antyutleniacz antyutleniaczy : właściwości i metody oznaczania

  2017cites this paper
• Skin permeation and antioxidant efficacy of topically applied resveratrol

  2017cites this paper
• In vitro -study of antioxidant extracts from Garcinia mangostana pericarp and Riesling grape pomace – a contribution to by-products valorization as cosmetic ingredients

  2016cites this paper
• α-Lipoic acid can not prevent effet on cell viability, collagen synthesis inhibition, collagen degradation induction in ultraviolet A irradiated human fibroblast cell

  2015cites this paper
• Modified Cellulosic Materials with Antioxidant and AntimicrobialProperties for Pharmaceutical Applications

  2015cites this paper
• Oxidative Stress in Aging Human Skin

  2015cites this paper
• Preparation and properties of phenolic compound/BTCA treated cotton fabrics for functional textile applications

  2015cites this paper
• OPTIMATION OF GREEN TEA WASTE AXTRACTION USING MICROWAVE ASSISTED EXTRACTION TO YIELD GREEN TEA EXTRACT

  2015cites this paper
• Gallic acid vehiculized through liposomes or mixed micelles in biofunctional textiles

  2014cites this paper
• Textiles with gallic acid microspheres: in vitro release characteristics

  2014cites this paper
• Antioxidative effects and percutaneous absorption of five polyphenols.

  2014cites this paper
• Antioxidant cosmeto-textiles: skin assessment.

  2013cites this paper
• Elaboration of integrated microelectrodes for the detection of antioxidant species

  2013cites this paper
• Optimum conditions for Radix Rehmanniae polysaccharides by RSM and its antioxidant and immunity activity in UVB mice.

  2013cites this paper
• Cosmetotextiles with Gallic Acid: Skin Reservoir Effect

  2013cites this paper
• Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR‐induced depletion, and protects against the formation of DNA damage (8‐hydroxy‐2'‐deoxyguanosine) in ex vivo human skin

  2013cites this paper
• Cholesterol photosensitized oxidation in food and biological systems.

  2013cites this paper
• Elaboration of integrated microelectrodes for the detection of antioxidant species

  2013cites this paper
• Carotenoid Lutein: A Promising Candidate for Pharmaceutical and Nutraceutical Applications

  2012cites this paper
• CLINICAL EVIDENCE SHOWS LONG-TERM BENEFICIAL EFFECTS OF FLORAGLO ® LUTEIN ON HUMAN SKIN

  2012cites this paper
• Chemical and Biological Aspects of Marine Cosmeceuticals

  2011cites this paper
• Assessment of cumulative exposure to UVA through the study of asymmetrical facial skin aging

  2010cites this paper
• TRADITIONAL MALAYSIAN SALADS (ULAM) AS A SOURCE OF ANTIOXIDANTS

  2010cites this paper
• The photoprotective activity of nutraceuticals.

  2009cites this paper
• An ex vivo methodology to assess the lipid peroxidation in stratum corneum.

  2009cites this paper
• Efeito de extratros vegetais com potencial antioxidante em fibroblastos submetidos à radiação UV

  2009cites this paper
• Fruits are rich in antioxidants and ripe for topical therapy

  2009cites this paper
• Determination of the antioxidative capacity of an antioxidant complex and idebenone: an in vitro rapid and sensitive method

  2008cites this paper
• Electrochemical microsensors for cutaneous surface analysis: Application to the determination of pH and the antioxidant properties of stratum corneum

  2008cites this paper
• Efficacy of oleuropein against UVB irradiation: preliminary evaluation

  2008cites this paper
• Beneficial Long-Term Effects of Combined Oral/Topical Antioxidant Treatment with the Carotenoids Lutein and Zeaxanthin on Human Skin: A Double-Blind, Placebo-Controlled Study

  2007cites this paper
• Vitamin E in human skin: organ-specific physiology and considerations for its use in dermatology.

  2007influential citation
• Chapter 8 Voltammetric sensors for the determination of antioxidant properties in dermatology and cosmetics

  2007cites this paper
• Generation and distribution of reactive oxygen species in the skin of hairless mice under UVA: studies on in vivo chemiluminescent detection and tape stripping methods

  2006cites this paper
• Vitamins and Polyphenols in Systemic Photoprotection

  2006cites this paper
• Exploration of the global antioxidant capacity of the stratum corneum by cyclic voltammetry.

  2006cites this paper
• PRODRUG STRATEGIES AIMED AT IMPROVING TOPICAL DELIVERY OF DRUGS USING THE N-ALKYL-N-ALKYLOXYCARBONYLAMINOMETHYL (NANAOCAM) PROMOIETY

  2006cites this paper
• Permeability and Antioxidant Barriers in Aged Epidermis

  2006cites this paper
• Further investigations on the role of ascorbic acid in stratum corneum lipid models after UV exposure

  2005cites this paper
• Untersuchung oxidativer Prozesse anhand induzierter ultraschwacher Photonenemission (UPE) : Anwendung für dermatologische und kosmetische Fragestellungen

  2005cites this paper
• The repair enzyme peptide methionine-S-sulfoxide reductase is expressed in human epidermis and upregulated by UVA radiation.

  2005cites this paper
• Evaluation of antioxidant properties of dermocosmetic creams by direct electrochemical measurements.

  2005cites this paper
• Polyunsaturated fatty acids partially reproduce the role of melanocytes in the epidermal melanin unit

  2005cites this paper
• Evaluation of the Antioxidant Capacity and Preventive Effects of a Topical Emulsion and Its Vehicle Control on the Skin Response to UV Exposure

  2005cites this paper
• Allergic contact dermatitis is accompanied by severe abnormal changes in antioxidativity of blood.

  2004cites this paper
• Delivery of vitamin E to the skin by a novel liquid skin cleanser: comparison of topical versus oral supplementation.

  2004cites this paper
• Vitamin E Delivery to Human Skin by a Rinse-Off Product: Penetration of α-Tocopherol versus Wash-Out Effects of Skin Surface Lipids

  2004cites this paper
• Role of oxidative stress and the antioxidant network in cutaneous carcinogenesis

  2004cites this paper
• Melatonin suppresses reactive oxygen species induced by UV irradiation in leukocytes

  2004cites this paper
• Oral Supplementation with All‐Rac‐ and RRR‐α‐Tocopherol Increases Vitamin E Levels in Human Sebum after a Latency Period of 14‐21 Days

  2004cites this paper
• Nutritional protection against skin damage from sunlight.

  2004cites this paper
• Oxidative stress in malignant melanoma and non‐melanoma skin cancer

  2003cites this paper
• Ultraviolet a induces generation of squalene monohydroperoxide isomers in human sebum and skin surface lipids in vitro and in vivo.

  2003cites this paper
• Die protektive Rolle von Vitamin E bei der UV-induzierten Alterung der Haut (Photoaging)

  2003cites this paper
• Cutaneous photodamage, oxidative stress, and topical antioxidant protection.

  2003cites this paper
• A rapid, accurate, and facile method to quantify the antioxidative capacity of topical formulations

  2003cites this paper
• Role of topical and nutritional supplement to modify the oxidative stress *

  2002cites this paper
• Photoaging is associated with protein oxidation in human skin in vivo.

  2002cites this paper
• Role of Ascorbic Acid in Stratum Corneum Lipid Models Exposed to UV Irradiation

  2002cites this paper
• The antioxidant network of the stratum corneum.

  2001cites this paper
• Oxidative targets in the stratum corneum. A new basis for antioxidative strategies.

  2001cites this paper
• Oxidative Targets in the Stratum corneum

  2001cites this paper
• Chapter 29 - Protection against solar radiation — protective properties of antioxidants

  2001cites this paper
• Protective effects of topical antioxidants in humans.

  2001cites this paper
• Untersuchungen zum zytotoxischen und zytoprotektiven Potential ausgewählter Radikalfänger an humanen Keratinozyten

  2001cites this paper
• Clinical Interventions in Aging Dovepress Assessment of Cumulative Exposure to Uva through the Study of Asymmetrical Facial Skin Aging

  year unknowncites this paper