The sodium channel blocker RS100642 reverses down-regulation of the sodium channel α-subunit Nav 1.1 expression caused by transient ischemic brain injury in rats

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Neurotoxicity research

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/BF03033382PMID 12835116
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Down-regulation of sodium channel Nav1.1 expression by veratridine and its reversal by a novel sodium channel blocker, RS100642, in primary neuronal cultures

  2009cited by this paper
• The importance of voltage-dependent sodium channels in cerebral ischaemia

  2005cited by this paper
• Differential pattern of expression of voltage-gated sodium channel genes following ischemic brain injury in rats

  2002cited by this paper
• Quantitative Real-Time RT—PCR Analysis of Inflammatory Gene Expression Associated with Ischemia—Reperfusion Brain Injury

  2002cited by this paper
• Neuroprotective effects of the sodium channel blocker RS100642 and attenuation of ischemia-induced brain seizures in the rat.

  2002cited by this paper
• RS-100642-198, a novel sodium channel blocker, provides differential neuroprotection against hypoxia/hypoglycemia, veratridine or glutamate-mediated neurotoxicity in primary cultures of rat cerebellar neurons

  2001cited by this paper
• Regulation of Na+ channel distribution in the nervous system.

  2001cited by this paper
• Review : Gene Expression after Cerebral Ischemia

  1999cited by this paper
• Neuroprotection (focal ischemia) and neurotoxicity (electroencephalographic) studies in rats with AHN649, a 3-amino analog of dextromethorphan and low-affinity N-methyl-D-aspartate antagonist.

  1999cited by this paper
• Anoxic and Ischemic Injury of Myelinated Axons in CNS White Matter: From Mechanistic Concepts to Therapeutics

  1998cited by this paper
• Distribution of the Tetrodotoxin-Resistant Sodium Channel PN3 in Rat Sensory Neurons in Normal and Neuropathic Conditions

  1998cited by this paper
• The role of polypeptide growth factors in recovery from stroke.

  1997cited by this paper
• Global Ischemia Induces Downregulation of Glur2 mRNA and Increases AMPA Receptor-Mediated Ca2+ Influx in Hippocampal CA1 Neurons of Gerbil

  1997cited by this paper
• Apoptosis Repressor Genes Bcl-2 and Bcl-x-Long are Expressed in the Rat Brain following Global Ischemia

  1997cited by this paper
• A Novel Tetrodotoxin-sensitive, Voltage-gated Sodium Channel Expressed in Rat and Human Dorsal Root Ganglia*

  1997cited by this paper
• A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons

  1996cited by this paper
• Structure and Function of a Novel Voltage-gated, Tetrodotoxin-resistant Sodium Channel Specific to Sensory Neurons (*)

  1996cited by this paper
• A novel, abundant sodium channel expressed in neurons and glia

  1995cited by this paper
• The ischaemic penumbra: twenty years on.

  1995cited by this paper
• Type III sodium channel mRNA is expressed in embryonic but not adult spinal sensory neurons, and is reexpressed following axotomy.

  1994cited by this paper
• Comparative study of voltage-sensitive sodium channel blockers in focal ischaemia and electric convulsions in rodents.

  1994cited by this paper
• Postnatal development of voltage sensitive Na+ channels in rat brain

  1994influential reference
• Differential Expression of the Immediate Early Genes c-Fos, c-Jun, JunB, and NGFI-B in the Rat Brain following Transient Forebrain Ischemia

  1994cited by this paper
• Human neocortical excitability is decreased during anoxia via sodium channel modulation.

  1993cited by this paper
• Cellular and molecular biology of voltage-gated sodium channels.

  1992cited by this paper
• Differential responses of neocortical neurons to glucose and/or O2 deprivation in the human and rat.

  1992cited by this paper
• Downregulation of sodium channels during anoxia: a putative survival strategy of turtle brain.

  1992cited by this paper
• The glial voltage-gated sodium channel: cell- and tissue-specific mRNA expression.

  1992cited by this paper
• Down-regulation of voltage-dependent sodium channels initiated by sodium influx in developing neurons.

  1990influential reference
• Cerebral hypoxia: some new approaches and unanswered questions

  1990cited by this paper
• Anoxia produces smaller changes in synaptic transmission, membrane potential, and input resistance in immature rat hippocampus.

  1989cited by this paper
• ATP and Brain Function

  1989cited by this paper
• A rat brain Na+ channel alpha subunit with novel gating properties.

  1988cited by this paper
• Primary structure of rat brain sodium channel III deduced from the cDNA sequence

  1988cited by this paper
• A rat brain na + channel α subunit with novel gating properties

  1988cited by this paper
• Existence of distinct sodium channel messenger RNAs in rat brain

  1986cited by this paper
• Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence

  1984cited by this paper

• HF-rTMS improves swallowing function in rats with poststroke dysphagia by increasing nucleus tractus solitarius excitability through the NMDAR1-Npas4-Nav1.1 pathway.

  2025cites this paper
• Neuroprotective effects of the new Na channel blocker rs100642 in global ischemic brain injury

  2019cites this paper
• A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.

  2014cites this paper
• Effect of electroacupuncture therapy on the expression of Na(v)1.1 and Na(v)1.6 in rat after acute cerebral ischemia

  2010cites this paper
• Effect of electroacupuncture on the expression of Nav1·1 in rat after acute cerebral ischemia

  2010cites this paper
• Neuroproteomics: A Biochemical Means To Discriminate the Extent and Modality of Brain Injury

  2010cites this paper
• Effect of the proteasome inhibitor MLN519 on the expression of inflammatory molecules following middle cerebral artery occlusion and reperfusion in the rat

  2009cites this paper
• The methodology of neuroproteomics.

  2009cites this paper
• Gene Expression in Cerebral Ischemia: A New Approach for Neuroprotection

  2006cites this paper
• Down-regulation of the sodium channel Na(v)1.1 alpha-subunit following focal ischemic brain injury in rats: in situ hybridization and immunohistochemical analysis.

  2005cites this paper
• Microarray analysis of acute and delayed gene expression profile in rats after focal ischemic brain injury and reperfusion

  2004cites this paper