Apolipoprotein J/Clusterin Prevents a Progressive Glomerulopathy of Aging

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Molecular and Cellular Biology

• Publication date

  2002-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/MCB.22.6.1893-1902.2002PMID 11865066PMCID PMC135592
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Clusterin is up-regulated in glomerular mesangial cells in complement-mediated injury.

  2001cited by this paper
• Effects of a vitamin E-modified dialysis membrane on neutrophil superoxide anion radical production.

  2001cited by this paper
• Apolipoprotein J/clusterin limits the severity of murine autoimmune myocarditis.

  2000cited by this paper
• Administration of IgG Fc Fragments Prevents Glomerular Injury in Experimental Immune Complex Nephritis1

  2000cited by this paper
• Systemic lupus erythematosus, a disease associated with low levels of clusterin/apoJ, an antiinflammatory protein.

  1999cited by this paper
• Glomerular Capillary Wall Basement Membrane Really Does Have Laminae Lucidae: A Defense

  1999cited by this paper
• Glomerular inflammation: use of genetically deficient mice to elucidate the roles of leukocyte adhesion molecules and Fc-gamma receptors in vivo.

  1999cited by this paper
• Immune complex size and complement regulate cytokine production by peripheral blood mononuclear cells.

  1999cited by this paper
• Clusterin Has Chaperone-like Activity Similar to That of Small Heat Shock Proteins*

  1999cited by this paper
• Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis.

  1998cited by this paper
• Distinct contribution of Fc receptors and angiotensin II-dependent pathways in anti-GBM glomerulonephritis.

  1998cited by this paper
• Resistance of Fc receptor- deficient mice to fatal glomerulonephritis.

  1998cited by this paper
• In vitro induction of proinflammatory cytokine secretion by juvenile rheumatoid arthritis synovial fluid immune complexes.

  1997cited by this paper
• Clusterin and the kidney.

  1995cited by this paper
• Fc receptors: rubor redux.

  1994cited by this paper
• Clusterin depletion enhances immune glomerular injury in the isolated perfused kidney.

  1994cited by this paper
• The role of clusterin in tissue injury.

  1994cited by this paper
• Clusterin binds by a multivalent mechanism to the Fc and Fab regions of IgG.

  1992cited by this paper
• Membrane attack complex (MAC) deposits in skin are not always accompanied by S-protein and clusterin.

  1992cited by this paper
• Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease

  1992cited by this paper
• SP‐40,40, a protein involved in the control of the complement pathway, possesses a unique array of disulphide bridges

  1992cited by this paper
• The glomerular mesangium: role in initiation and progression of renal injury.

  1991cited by this paper
• Localization of clusterin in the epimembranous deposits of passive Heymann nephritis.

  1991cited by this paper
• Molecular structure and functional characterization of a human complement cytolysis inhibitor found in blood and seminal plasma: identity to sulfated glycoprotein 2, a constituent of rat testis fluid.

  1989cited by this paper
• Localization of Terminal Complement Components, S‐Protein and Sp‐40,40 in Renal Biopsies

  1989cited by this paper
• A specific Fc gamma receptor on cultured rat mesangial cells.

  1989cited by this paper
• SP-40,40, a newly identified normal human serum protein found in the SC5b-9 complex of complement and in the immune deposits in glomerulonephritis.

  1988cited by this paper
• The glomerular mesangium: I. Kinetic studies of macromolecular uptake in normal and nephrotic rats

  1972cited by this paper
• Immune complex disease. II. The role of circulatory dynamics and glomerular filtration in the development of experimental glomerulonephritis.

  1967cited by this paper
• Immune complex disease. II. The role of circulatory dynamics and glomerular filtration in the development of experimental glomerulonephritis.

  1967cited by this paper

• Apolipoprotein J-mediated hepato-renal crosstalk drives renal injury in chronic kidney disease.

  2026cites this paper
• Elucidating the function of clusterin in the progression of diabetic kidney disease

  2025cites this paper
• Cockayne syndrome mice reflect human kidney disease and are defective in de novo NAD biosynthesis

  2025cites this paper
• Revisiting Glomerulopathy in Clusterin Knockout Mice: A Mouse Model of Human Immunotactoid Glomerulopathy

  2025cites this paper
• Chaperone-Mediated Responses and Mitochondrial–Endoplasmic Reticulum Coupling: Emerging Insight into Alzheimer’s Disease

  2025cites this paper
• Apoc1 Knockdown Alleviates High Glucose-induced Oxidative Stress and Apoptosis of Renal Tubular Cells by Binding to Clusterin

  2024cites this paper
• 1,25 DIHYDROXYVITAMIN D3-MEDIATED EFFECTS ON BOVINE INNATE IMMUNITY AND ON BIOFILM-FORMING Staphylococcus spp. ISOLATED FROM CATTLE WITH MASTITIS.

  2024cites this paper
• The Ins and Outs of Clusterin: Its Role in Cancer, Eye Diseases and Wound Healing

  2023cites this paper
• Clusterin is a Potential Therapeutic Target in Alzheimer’s Disease

  2023cites this paper
• A 3-Mbp fragment on rat chromosome 1 affects susceptibility both to stroke and kidney injury under salt loading in the stroke-prone spontaneously hypertensive rat: a genetic approach using multiple congenic strains

  2022cites this paper
• The functions of clusterin in renal mesenchymal stromal cells: Promotion of cell growth and regulation of macrophage activation.

  2022cites this paper
• Membrane attack complexes, endothelial cell activation, and direct allorecognition

  2022cites this paper
• The Roles of Fatty Acids and Apolipoproteins in the Kidneys

  2022cites this paper
• Clusterin, other extracellular chaperones, and eye disease.

  2021cites this paper
• Genetic signature of human longevity in PKC and NF‐κB signaling

  2021cites this paper
• The Functions of Clusterin Expression in Renal Mesenchymal Stromal Cells: Regulation of Cell Proliferation and Macrophage Activation

  2021cites this paper
• Evaluation of urinary clusterin and cystatin B as biomarkers for renal injury in dogs envenomated by the European adder (Vipera berus).

  2021cites this paper
• Therapeutic Potential of the Molecular Chaperone and Matrix Metalloproteinase Inhibitor Clusterin for Dry Eye

  2020cites this paper
• Complement in Neurologic Disease.

  2020cites this paper
• Clusterin regulates macrophage expansion, polarization and phagocytic activity in response to inflammation in the kidneys

  2020cites this paper
• Clusterin Deficiency Predisposes C57BL/6j Mice to Cationic Bovine Serum Albumin-Induced Glomerular Inflammation

  2020cites this paper
• Identification of Novel Putative Urinary Markers of Endometriosis by High-Resolution Quantitative Proteomics

  2020cites this paper
• Heparan sulfate is a clearance receptor for aberrant extracellular proteins

  2020cites this paper
• Glomerular clusterin expression is increased in diabetic nephropathy and protects against oxidative stress-induced apoptosis in podocytes

  2020cites this paper
• Salient Genetic and Proteomic Pathways in Glaucoma

  2020cites this paper
• High serum clusterin levels are associated with premature coronary artery disease in a Chinese population

  2019cites this paper
• Hepatocyte-specific clusterin overexpression attenuates diet-induced nonalcoholic steatohepatitis.

  2018cites this paper
• Urinary clusterin—a novel urinary biomarker associated with pediatric lupus renal histopathologic features and renal survival

  2018cites this paper
• Clusterin deficiency induces lipid accumulation and tissue damage in kidney.

  2018cites this paper
• A Role for Clusterin in Exfoliation Syndrome and Exfoliation Glaucoma?

  2018cites this paper
• Toll-like receptor 4 signaling is required for clusterin-induced tumor necrosis factor-α secretion in macrophage.

  2017cites this paper
• Urine clusterin/apolipoprotein J is linked to tubular damage and renal outcomes in patients with type 2 diabetes mellitus

  2017cites this paper
• Protective effect of clusterin on rod photoreceptor in rat model of retinitis pigmentosa

  2017cites this paper
• Clusterin as a therapeutic target

  2017cites this paper
• Clusterin facilitates in vivo clearance of extracellular misfolded proteins

  2016cites this paper
• Clusterin in cancer: Dual role as a tumor suppressor gene and an oncogene

  2016cites this paper
• Apolipoprotein (a) as a Predictor of Cardiovascular Diseases among Type 2 Diabetes patients in Gaza Strip

  2016cites this paper
• Clusterin in the eye: An old dog with new tricks at the ocular surface.

  2016cites this paper
• Implication of Molten Globule on the Function and Toxicity of a Protein

  2016cites this paper
• Requirement of clusterin expression for prosurvival autophagy in hypoxic kidney tubular epithelial cells.

  2016cites this paper
• Mining kidney toxicogenomic data by using gene co-expression modules

  2016cites this paper
• Relationship of clusterin with renal inflammation and fibrosis after the recovery phase of ischemia-reperfusion injury

  2016cites this paper
• The Role of Clusterin in Carcinogenesis and its Potential Utility as Therapeutic Target.

  2016cites this paper
• The CLU-files: disentanglement of a mystery

  2016cites this paper
• The Role of proteases and chaperones in extracellular proteostasis

  2015cites this paper
• Clusterin Seals the Ocular Surface Barrier in Mouse Dry Eye

  2015cites this paper
• Inhibition of intracellular clusterin attenuates cell death in nephropathic cystinosis.

  2015cites this paper
• MOLECULAR ASPECTS OF APOPROTEIN J

  2015cites this paper
• Promotion of cell proliferation by clusterin in the renal tissue repair phase after ischemia-reperfusion injury.

  2014cites this paper
• Chronic Neurodegeneration Brain-restricted Production of Clusterin in Astrocytic Signature and Highlights the ME7 Prion Disease Reveals a Predominant Analysis of the Hippocampal Proteome in Neurobiology:

  2014cites this paper
• Cholesterol in brain disease: sometimes determinant and frequently implicated

  2014cites this paper
• From Humans to Experimental Models: The Cytoprotective Role of Clusterin in the Kidney

  2014cites this paper
• The physiological roles of apolipoprotein J/clusterin in metabolic and cardiovascular diseases

  2014cites this paper
• Unfolded protein response‐induced ERdj3 secretion links ER stress to extracellular proteostasis

  2014cites this paper
• Clusterin/Apolipoprotein J Attenuates Angiotensin II-Induced Renal Fibrosis

  2014cites this paper
• Extracellular chaperones.

  2013cites this paper
• The clusterin gene in mouse inner ear development: expression analysis and generation of reporter constructs

  2013cites this paper
• Extracellular chaperones and proteostasis.

  2013cites this paper
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  2013cites this paper
• Urinary clusterin as a renal marker in dogs

  2012cites this paper
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  2012cites this paper
• Clusterin attenuates the development of renal fibrosis.

  2012cites this paper
• Extracellular Chaperones

  2012cites this paper
• Over-expression of human clusterin increases stress resistance and extends lifespan in Drosophila melanogaster.

  2012cites this paper
• Novel Urinary Protein Biomarkers Predicting the Development of Microalbuminuria and Renal Function Decline in Type 1 Diabetes

  2012cites this paper
• Clusterin in Alzheimer's disease.

  2012cites this paper
• Interaction of clusterin and matrix metalloproteinase-9 and its implication for epithelial homeostasis and inflammation.

  2012cites this paper
• Proteomic Candidate Biomarkers of Drug-Induced Nephrotoxicity in the Rat

  2012cites this paper
• Preclinical perspective of urinary biomarkers for the detection of nephrotoxicity: what we know and what we need to know.

  2011cites this paper
• Differential effects of growth hormone versus insulin-like growth factor-I on the mouse plasma proteome.

  2011cites this paper
• Clusterin facilitates in vivo clearance of extracellular misfolded proteins

  2011cites this paper
• Proteomic Analyses of Host and Pathogen Responses during Bovine Mastitis

  2011cites this paper
• Apolipoprotein-J Prevention of Cardiac Myobalst Apoptosis Induced by Ethanol

  2011cites this paper
• Comparative profile of commercially available urinary biomarkers in preclinical drug-induced kidney injury and recovery in rats.

  2011cites this paper
• The Translationally Controlled Tumor Protein (TCTP) associates to and destabilizes the Circadian Factor Period 2 (Per2)

  2010cites this paper
• The proteomic advantage: label-free quantification of proteins expressed in bovine milk during experimentally induced coliform mastitis.

  2010cites this paper
• Clusterin induces CXCR4 expression and migration of cardiac progenitor cells.

  2010cites this paper
• Clusterin/Apo J protein expression in plasma samples of an elderly Sardinian population

  2010cites this paper
• Low Clusterin Levels in High-Density Lipoprotein Associate With Insulin Resistance, Obesity, and Dyslipoproteinemia

  2010cites this paper
• Loss of clusterin expression worsens renal ischemia-reperfusion injury.

  2010cites this paper
• Clusterin : A Multifacet Protein at the Crossroad of Inflammation and Autoimmunity

  2009cites this paper
• Chapter 9: Oxidative stress in malignant progression: The role of Clusterin, a sensitive cellular biosensor of free radicals.

  2009cites this paper
• Structural Characterization of Clusterin-Chaperone Client Protein Complexes*

  2009cites this paper
• A Proteomic Approach to Identify Biomarkers for Growth Hormone and Aging

  2009cites this paper
• Differential Regulation of Clusterin Isoforms by the Androgen Receptor

  2009cites this paper
• Identification of Human Plasma Proteins as Major Clients for the Extracellular Chaperone Clusterin*

  2009cites this paper
• The role of clusterin (CLU) in extracellular protein folding quality control.

  2009cites this paper
• Chapter 6: The chaperone action of Clusterin and its putative role in quality control of extracellular protein folding.

  2009cites this paper
• Expression of clusterin in normal and preeclamptic placentas

  2008cites this paper
• The effects of ACE inhibitor and angiotensin receptor blocker on clusterin and apoptosis in the kidney tissue of streptozotocin-diabetic rats

  2008cites this paper
• Structure and function studies of recombinant clusterin

  2007cites this paper
• The role of clusterin in retinal development and free radical damage

  2007cites this paper
• Effects of glycosylation on the structure and function of the extracellular chaperone clusterin.

  2007cites this paper
• Apolipoprotein-J prevention of fetal cardiac myoblast apoptosis induced by ethanol.

  2007cites this paper
• Beneficial effects of r-h-CLU on disease severity in different animal models of peripheral neuropathies.

  2007cites this paper
• Chapter 2 Pathogenesis of Renal Disease: Complement

  2007cites this paper
• Glomerular clusterin is associated with PKC-α/β regulation and good outcome of membranous glomerulonephritis in humans

  2007cites this paper
• Clusterin deficiency in eyes with pseudoexfoliation syndrome may be implicated in the aggregation and deposition of pseudoexfoliative material.

  2006cites this paper
• The complement system in renal diseases

  2006cites this paper
• Glomerular clusterin is associated with PKC-alpha/beta regulation and good outcome of membranous glomerulonephritis in humans.

  2006cites this paper