Air pollution particles mediated oxidative DNA base damage in a cell free system and in human airway epithelial cells in relation to particulate metal content and bioreactivity.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Chemical Research in Toxicology

• Publication date

  2001-06-28

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1021/TX010022EPMID 11453735
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Interleukin-8 levels in human lung epithelial cells are increased in response to coal fly ash and vary with the bioavailability of iron, as a function of particle size and source of coal.

  2000cited by this paper
• Enhancement of 2'-deoxyguanosine hydroxylation and DNA damage by coal and oil fly ash in relation to particulate metal content and availability.

  2000cited by this paper
• Ambient air particles: effects on cellular oxidant radical generation in relation to particulate elemental chemistry.

  1999cited by this paper
• Mobilization of iron from coal fly ash was dependent upon the particle size and the source of coal.

  1998cited by this paper
• Cytokine production by human airway epithelial cells after exposure to an air pollution particle is metal-dependent.

  1997cited by this paper
• Formation, Prevention, and Repair of DNA Damage by Iron/Hydrogen Peroxide*

  1997cited by this paper
• In vivo evidence of free radical formation in the rat lung after exposure to an emission source air pollution particle.

  1997cited by this paper
• Mobilization of iron from urban particulates leads to generation of reactive oxygen species in vitro and induction of ferritin synthesis in human lung epithelial cells.

  1997cited by this paper
• LUMINOL-ENHANCED CHEMILUMINESCENCE AFTER IN VITRO EXPOSURES OF RAT ALVEOLAR MACROPHAGES TO OIL FLY ASH IS METAL DEPENDENT

  1997cited by this paper
• HUMIC-LIKE SUBSTANCES IN AIR POLLUTION PARTICULATES CORRELATE WITH CONCENTRATIONS OF TRANSITION METALS AND OXIDANT GENERATION

  1996cited by this paper
• Vanadium(IV)-mediated free radical generation and related 2'-deoxyguanosine hydroxylation and DNA damage.

  1996cited by this paper
• Oxidative Damage to DNA Constituents by Iron-mediated Fenton Reactions

  1996cited by this paper
• Oxidative Damage to DNA Constituents by Iron-mediated Fenton Reactions

  1996cited by this paper
• Oxidant Generation and Lung Injury after Particulate Air Pollutant Exposure Increase with the Concentrations of Associated Metals

  1996cited by this paper
• Oxidative mechanisms in the toxicity of metal ions.

  1995cited by this paper
• Metal-catalyzed oxidative degradation of DNA: base damage and mechanistic aspects.

  1994cited by this paper
• Air pollution and daily mortality: a review and meta analysis.

  1994cited by this paper
• Concentrations of Metal Elements in Mouse Lung After Intratracheal Administration of Coal Fly Ash

  1994cited by this paper
• The Structure and Reaction Processes of Coal

  1994cited by this paper
• The effect of crystallinity on hydroxyapatite‐induced production of reactive oxygen metabolites by polymorphonuclear leukocytes

  1993cited by this paper
• Radical oxidation reactions of the purine moiety of 2'-deoxyribonucleosides and DNA by iron-containing minerals.

  1993cited by this paper
• An association between air pollution and mortality in six U.S. cities.

  1993cited by this paper
• Particulate air pollution and hospitalization for asthma.

  1992cited by this paper
• Assays for 8-hydroxy-2'-deoxyguanosine: a biomarker of in vivo oxidative DNA damage.

  1991cited by this paper
• Iron Mobilization from Crocidolite Results in Enhanced Iron-Catalyzed Oxygen Consumption and Hydroxyl Radical Generation in the Presence of Cysteine

  1991cited by this paper
• Fenton chemistry. Amino acid oxidation.

  1991cited by this paper
• Urban air quality and chronic respiratory disease

  1990cited by this paper
• Enhancement of hydroxylation and deglycosylation of 2'-deoxyguanosine by carcinogenic nickel compounds.

  1989cited by this paper
• Phagocytosis of latex particles by leucocytes. I. Dependence of phagocytosis on the size and surface potential of particles.

  1986cited by this paper
• Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents.

  1984cited by this paper

• Multi-dimensional assessment of metal welding fumes exposure and oxidative stress-driven health risks: Insights from external monitoring, respiratory replica monitoring, and DTT activity.

  2026cites this paper
• Emission dynamics of reactive oxygen species and oxidative potential in particles from a petrol car and wood stove

  2025cites this paper
• Oxidative potential of atmospheric aerosols: Research progress on pollution characteristics and mechanism.

  2025cites this paper
• Pro-Inflammatory and Oxidative Responses to Burn Pit Relevant Desert Particulate Matter in Macrophages: A Role for TLR2 Signaling.

  2025cites this paper
• Dysfunction of Nrf2-regulated cellular defence system and JNK activation induced by high dose of fly Ash particles are associated with pulmonary injury in mouse lungs.

  2024cites this paper
• Effects of Particulate Matter Inhalation during Exercise on Oxidative Stress and Mitochondrial Function in Mouse Skeletal Muscle

  2024cites this paper
• Wildfire Smoke: Health Effects, Mechanisms, and Mitigation.

  2024cites this paper
• Molecular characterization of major oxidative potential active species in ambient PM2.5: Emissions from biomass burning and ship exhaust.

  2024cites this paper
• Reactive oxygen species, environmentally persistent free radicals, and oxidative potential of outdoor and indoor particulate matter in Wintertime Fairbanks, Alaska

  2024cites this paper
• Effects of differential regional PM2.5 induced hepatic steatosis and underlying mechanism.

  2023cites this paper
• Carbon nanotubes: Structural defects as stressors inducing lung cell toxicity.

  2023cites this paper
• An Automated Online Field Instrument to Quantify the Oxidative Potential of Aerosol Particles via Ascorbic Acid Oxidation

  2023cites this paper
• PARTICULATE MATTER AIR POLLUTION IS A SIGNIFICANT RISK FACTOR FOR CARDIOVASCULAR DISEASE.

  2023cites this paper
• Rapid Assessment of Oxidative Damage Potential: A Comparative Study of Engineered Stone Dusts Using a Deoxyguanosine Assay

  2022cites this paper
• A comparative study of persistent DNA oxidation and chromosomal instability induced in vitro by oxidizers and reference airborne particles.

  2022cites this paper
• Physicochemical characterization and oxidative potential of size fractionated Particulate Matter: Uptake, genotoxicity and mutagenicity in V-79 cells.

  2022cites this paper
• Oxidative potential of size-segregated particulate matter in the dust-storm impacted Hotan, northwest China

  2022cites this paper
• Seasonal variation of driving factors of ambient PM2.5 oxidative potential in Shenzhen, China.

  2022cites this paper
• Mechanisms underlying the health effects of desert sand dust

  2021cites this paper
• Environmental Exposures and Lung Aging: Molecular Mechanisms and Implications for Improving Respiratory Health

  2021cites this paper
• PM2.5 and Trace Elements in Underground Shopping Districts in the Seoul Metropolitan Area, Korea

  2021cites this paper
• Pemberian Glutathion Setelah Aktivitas Fisik Submaksimal Mampu Menurunkan Kadar MDA (Malondialdehyde) Plasma Darah

  2021cites this paper
• Comparison of indoor and outdoor oxidative potential of PM2.5: pollution levels, temporal patterns, and key constituents.

  2021cites this paper
• Predicting Spatial Variations in Multiple Measures of Oxidative Burden for Outdoor Fine Particulate Air Pollution across Canada.

  2021cites this paper
• Pulmonary oxidative stress and apoptosis in mice chronically exposed to hydrothermal volcanic emissions

  2021cites this paper
• IMPACT OF POLYCYCLIC AROMATIC HYDROCARBONS ON MALE REPRODUCTIVE HEALTH IN COAL TAR WORKERS

  2020cites this paper
• Characterization of water-insoluble oxidative potential of PM2.5 using the dithiothreitol assay

  2020cites this paper
• Integration between Monitoring and Bio-monitoring Systems to Assessment the Impacts of Normal Levels of Environmental Pollutants

  2020cites this paper
• Toxicity of fine and quasi-ultrafine particles: Focus on the effects of organic extractable and non-extractable matter fractions.

  2020cites this paper
• The effect of toxic components on metabolomic response of male SD rats exposed to fine particulate matter.

  2020cites this paper
• Correlation of α/γ-Fe2O3 nanoparticles with the toxicity of particulate matter originating from subway tunnels in Seoul stations, Korea.

  2020cites this paper
• Long-term exposure to atmospheric metals assessed by mosses and mortality in France.

  2019cites this paper
• Role of Chemical Exposure in Oxidant-Mediated Lung Diseases

  2019cites this paper
• Review of Acellular Assays of Ambient Particulate Matter Oxidative Potential: Methods and Relationships with Composition, Sources, and Health Effects.

  2019cites this paper
• Using Nrf2/antioxidant response element-dependent signaling to assess the toxicity potential of fly ash particles.

  2019cites this paper
• The use of Sentinel Organisms to evaluate the health of metal contaminated forest ecosystems in the Western Cape, South Africa

  2019cites this paper
• Short-term effects of particle size fractions on lung function of late adolescents

  2018cites this paper
• 5 Ambient Air Pollution and Reproductive Health

  2018cites this paper
• Soil Quality and Human Health

  2018cites this paper
• Airborne Particulate Matter: Human Exposure and Health Effects

  2018cites this paper
• PM2.5 Meets Blood: In vivo Damages and Immune Defense

  2018cites this paper
• Particulate matter air pollution and respiratory impact on humans and animals

  2018cites this paper
• Environmentally Persistent Free Radicals: Insights on a New Class of Pollutants.

  2018cites this paper
• Spatiotemporal modeling of PM2.5 oxidative potential using source impact and model fusion techniques

  2018influential citation
• Les particules diesel : impact sur la santé et moyens de lutte en France

  2017cites this paper
• Oxidative Stress: Comparing Sub-Maximal Physical Activities as a Self-Reminder for Human Health System

  2017cites this paper
• Effects of Fine Particulate Matter on Erectile Function and Its Potential Mechanism in Rats.

  2017cites this paper
• Predictive and Prognostic Biomarkers of Respiratory Diseases due to Particulate Matter Exposure

  2017cites this paper
• Analytical methods to assess the oxidative potential of nanoparticles: a review

  2017cites this paper
• Protective effects of chebulic acid on alveolar epithelial damage induced by urban particulate matter

  2017cites this paper
• Evaluation of Sources and Patterns of Elemental Composition of PM2.5 at Three Low-Income Neighborhood Schools and Residences in Quito, Ecuador

  2017cites this paper
• Air pollution and childhood bronchitis: Interaction with xenobiotic, immune regulatory and DNA repair genes.

  2016cites this paper
• Cytotoxicity and genotoxicity induced in vitro by solvent-extractable organic matter of size-segregated urban particulate matter.

  2016cites this paper
• Atmospheric particulate matter (PM10) exposure-induced cell cycle arrest and apoptosis evasion through STAT3 activation via PKCζ and Src kinases in lung cells.

  2016cites this paper
• Multiple exposures to environmental pollutants and oxidative stress: Is there a sex specific risk of developmental complications for fetuses?

  2016cites this paper
• Speciation of water soluble iron in size segregated airborne particulate matter using LED based liquid waveguide with a novel dispersive absorption spectroscopic measurement technique.

  2016cites this paper
• PM10 mass concentration and oxidative capacity of moxa smoke.

  2015cites this paper
• Toxicity of particulate matter from incineration of nanowaste

  2015cites this paper
• Production of hydroxyl radicals from Fe-containing fine particles in Guangzhou, China

  2015cites this paper
• Reactive Oxygen Species Production Mediated by Humic-like Substances in Atmospheric Aerosols: Enhancement Effects by Pyridine, Imidazole, and Their Derivatives.

  2015cites this paper
• Magnetic nanoparticles – DNA interactions: design and applications of nanobiohybrid systems

  2014cites this paper
• Source and mixing state of iron-containing particles in Shanghai by individual particle analysis.

  2014cites this paper
• Effect of Copper Oxide Concentration on the Formation and Persistency of Environmentally Persistent Free Radicals (EPFRs) in Particulates

  2014cites this paper
• Mammalian cell-transforming potential of traffic-linked ultrafine particulate matter PM0.056 in urban roadside atmosphere.

  2014cites this paper
• Vanadate from Air Pollutant Inhibits Hrs-Dependent Endosome Fusion and Augments Responsiveness to Toll-Like Receptors

  2014cites this paper
• The Protective Role of Antioxidants in the Defence against ROS/RNS-Mediated Environmental Pollution

  2014cites this paper
• Oxidative stress and inflammation generated DNA damage by exposure to air pollution particles.

  2014cites this paper
• The association of PM(2.5) with full term low birth weight at different spatial scales.

  2014cites this paper
• Oxidative capacities of size-segregated haze particles in a residential area of Beijing.

  2014cites this paper
• Superoxo radical scavenging action by common analgesic drug paracetamol: A model kinetic study

  2013cites this paper
• Determination of aerosol oxidative activity using silver nanoparticle aggregation on paper-based analytical devices.

  2013cites this paper
• An evaluation of the toxicological aspects and potential doses from the inhalation of coal combustion products

  2013influential citation
• Regular exercise training attenuates pulmonary inflammatory responses to inhaled alumina refinery dust in mice.

  2013cites this paper
• Chronic exposure to volcanogenic air pollution as cause of lung injury.

  2013cites this paper
• ATR-IR study of ozone initiated heterogeneous oxidation of squalene in an indoor environment.

  2013cites this paper
• ORAL ARGUMENT NOT YET SCHEDULED IN THE UNITED STATES COURT OF APPEALS FOR THE DISTRICT OF COLUMBIA CIRCUIT

  2013cites this paper
• Ultrafine Particles Alter Endothelial Phenotype Through Oxidant Signaling

  2013cites this paper
• Cytotoxicity in the age of nano: the role of fourth period transition metal oxide nanoparticle physicochemical properties.

  2013cites this paper
• Cell cycle alterations induced by urban PM2.5 in bronchial epithelial cells: characterization of the process and possible mechanisms involved

  2013cites this paper
• Mechanisms of allergic diseases

  2013cites this paper
• Interactive enhancements of ascorbic acid and iron in hydroxyl radical generation in quinone redox cycling.

  2012cites this paper
• Genotoxic effects and oxidative stress induced by organic extracts of particulate matter(PM 10)collected from a subway tunnel in Seoul, Korea.

  2012cites this paper
• Toxicology of ambient particulate matter.

  2012cites this paper
• Composition of Air Pollution Particles and Oxidative Stress in Cells, Tissues, and Living Systems

  2012cites this paper
• Global gene expression changes in human embryonic lung fibroblasts induced by organic extracts from respirable air particles

  2012cites this paper
• Molecular, Clinical and Environmental Toxicology

  2012cites this paper
• Environment, Epigenetics, and Cardiovascular Health

  2012cites this paper
• Reactive oxygen species, inflammation, and lung diseases.

  2012cites this paper
• From particles to patients: oxidative stress and the cardiovascular effects of air pollution.

  2012cites this paper
• Formation of hydroxyl radical from San Joaquin Valley particles extracted in a cell-free surrogate lung fluid.

  2011influential citation
• Caractérisation physicochimique et étude des effets toxiques sur des cellules pulmonaires BEAS-2B des polluants particulaires de la ville de Dakar (Sénégal)

  2011cites this paper
• Airborne particulate matter, hydroxyl radical production and cellular toxicity

  2011cites this paper
• Formation and Stabilization of Combustion-Generated Environmentally Persistent Free Radicals on Transition Metal Oxides Supported on Silica

  2011cites this paper
• Oxidative stress and DNA damage responses in rat and mouse lung to inhaled carbon nanoparticles

  2011cites this paper
• Potential of In Vitro Methods for Mechanistic Studies of Particulate Matter–Induced Cardiopulmonary Toxicity

  2011cites this paper
• Project 2 (NAS): Cognitive Decline, Cardiovascular Changes, and Biological Aging in Response to Air Pollution

  2011cites this paper
• Organic extracts of urban air pollution particulate matter (PM2.5)-induced genotoxicity and oxidative stress in human lung bronchial epithelial cells (BEAS-2B cells).

  2011cites this paper
• Low dose of fine particulate matter (PM2.5) can induce acute oxidative stress, inflammation and pulmonary impairment in healthy mice

  2011cites this paper
• Ambient Air Pollution and Reproductive Health

  2011cites this paper
• In vitro studies: Ups and downs of cellular uptake.

  2011cites this paper