Urocortins and corticotropin releasing factor type 2 receptors in the hypothalamus and the cardiovascular system.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Peptides

• Publication date

  2004-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.PEPTIDES.2004.05.024PMID 15476938
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Urocortin-II and urocortin-III are cardioprotective against ischemia reperfusion injury: an essential endogenous cardioprotective role for corticotropin releasing factor receptor type 2 in the murine heart.

  2004cited by this paper
• Expression of urocortin III/stresscopin in human heart and kidney.

  2004cited by this paper
• Effect of Stress and Adrenalectomy on Urocortin II mRNA Expression in the Hypothalamic Paraventricular Nucleus of the Rat

  2003cited by this paper
• Corticotropin-releasing factor receptor-2-deficient mice display abnormal homeostatic responses to challenges of increased dietary fat and cold.

  2003cited by this paper
• Vasodilative Effects of Urocortin II via Protein Kinase A and a Mitogen-activated Protein Kinase in Rat Thoracic Aorta

  2003cited by this paper
• Modulation of corticotropin-releasing hormone receptor type 2 mRNA expression by CRH deficiency or stress in the mouse heart.

  2003cited by this paper
• Effects of a selective agonist and antagonist of CRF2 receptors on cardiovascular function in the rat.

  2003cited by this paper
• Locomotor suppressive and anxiolytic-like effects of urocortin 3, a highly selective type 2 corticotropin-releasing factor agonist.

  2003cited by this paper
• Protective effects of the urocortin homologues stresscopin (SCP) and stresscopin-related peptide (SRP) against hypoxia/reoxygenation injury in rat neonatal cardiomyocytes.

  2003cited by this paper
• Human Urocortin II, a Selective Agonist for the Type 2 Corticotropin-Releasing Factor Receptor, Decreases Feeding and Drinking in the Rat

  2003cited by this paper
• Corticotropin-releasing factor receptor type 2 messenger ribonucleic acid in rat pituitary: localization and regulation by immune challenge, restraint stress, and glucocorticoids.

  2003cited by this paper
• Glucocorticoids regulate the expression of the mouse urocortin II gene: a putative connection between the corticotropin-releasing factor receptor pathways.

  2003cited by this paper
• Down-regulation of corticotropin-releasing hormone receptor type 2beta mRNA expression in the rat cardiovascular system following food deprivation.

  2002cited by this paper
• Intracisternal urocortin inhibits vagally stimulated gastric motility in rats: role of CRF2

  2002cited by this paper
• Corticotropin-releasing factor receptors 1 and 2 in anxiety and depression.

  2002cited by this paper
• Urocortin-deficient mice show hearing impairment and increased anxiety-like behavior

  2002cited by this paper
• Pharmacological evidence supporting a role for central corticotropin-releasing factor(2) receptors in behavioral, but not endocrine, response to environmental stress.

  2002cited by this paper
• Mice Deficient for Both Corticotropin-Releasing Factor Receptor 1 (CRFR1) and CRFR2 Have an Impaired Stress Response and Display Sexually Dichotomous Anxiety-Like Behavior

  2002cited by this paper
• Urocortin III-Immunoreactive Projections in Rat Brain: Partial Overlap with Sites of Type 2 Corticotrophin-Releasing Factor Receptor Expression

  2002cited by this paper
• Urocortin-Deficient Mice Display Normal Stress-Induced Anxiety Behavior and Autonomic Control but an Impaired Acoustic Startle Response

  2002cited by this paper
• Human urocortin II: mild locomotor suppressive and delayed anxiolytic-like effects of a novel corticotropin-releasing factor related peptide.

  2002cited by this paper
• Expression of urocortin and corticotropin-releasing factor receptor subtypes in the human heart.

  2002cited by this paper
• Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor

  2001cited by this paper
• Coronary vasodilation and positive inotropism by urocortin in the isolated rat heart.

  2001cited by this paper
• Urocortin II: A member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors

  2001cited by this paper
• Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor

  2001cited by this paper
• Regulation of the hypothalamic-pituitary-adrenocortical system in mice deficient for CRH receptors 1 and 2.

  2001cited by this paper
• Attenuation of fear conditioning by antisense inhibition of brain corticotropin releasing factor-2 receptor.

  2001cited by this paper
• Antagonism of CRF(2) receptors produces anxiolytic behavior in animal models of anxiety.

  2001cited by this paper
• Urocortin protects against ischemic injury via a MAPK-dependent pathway.

  2001cited by this paper
• Regulation of the Hypothalamic-Pituitary-Adrenocortical System in Mice Deficient for CRH Receptors 1 and 2.

  2001cited by this paper
• Urocortin, a member of the corticotropin-releasing factor family, in normal and diseased heart.

  2000cited by this paper
• Regulation of type-2 corticotropin-releasing hormone receptor mRNA in rat heart by glucocorticoids and urocortin.

  2000cited by this paper
• Regulation of corticotropin-releasing factor receptor type 2 beta messenger ribonucleic acid in the rat cardiovascular system by urocortin, glucocorticoids, and cytokines.

  2000cited by this paper
• Regulation of Corticotropin-Releasing Factor Receptor Type 2β Messenger Ribonucleic Acid in the Rat Cardiovascular System by Urocortin, Glucocorticoids, and Cytokines.

  2000cited by this paper
• Urocortin in the ventromedial hypothalamic nucleus acts as an inhibitor of feeding behavior in rats.

  2000cited by this paper
• Oral administration of a corticotropin-releasing hormone receptor antagonist significantly attenuates behavioral, neuroendocrine, and autonomic responses to stress in primates.

  2000cited by this paper
• Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress

  2000cited by this paper
• Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin-releasing hormone receptor-2

  2000cited by this paper
• The Role of the CRH Type 1 Receptor in Autonomic Responses to Corticotropin-Releasing Hormone in the Rat

  2000cited by this paper
• Vasopressin and Oxytocin Neurones of Hypothalamic Supraoptic and Paraventricular Nuclei Co‐Express mRNA for Type‐1 andType‐2 Corticotropin‐Releasing Hormone Receptors

  2000cited by this paper
• Role of corticotropin-releasing factor (CRF) receptors in the anorexic syndrome induced by CRF.

  2000cited by this paper
• Deletion of Crhr2 reveals an anxiolytic role for corticotropin-releasing hormone receptor-2

  2000cited by this paper
• Modulation of Learning and Anxiety by Corticotropin-Releasing Factor (CRF) and Stress: Differential Roles of CRF Receptors 1 and 2

  1999cited by this paper
• The impact of the nonpeptide corticotropin-releasing hormone antagonist antalarmin on behavioral and endocrine responses to stress.

  1999cited by this paper
• Leptin Effects on the Expression of Type‐2 CRH Receptor mRNA in the Ventromedial Hypothalamus in the Rat

  1999cited by this paper
• Differential behavioural effects of chronic infusion of CRH 1 and CRH 2 receptor antisense oligonucleotides into the rat brain.

  1999cited by this paper
• Decreased Type 2 Corticotropin-Releasing Hormone Receptor mRNA Expression in the Ventromedial Hypothalamus during Repeated Immobilization Stress

  1999cited by this paper
• Urocortin Expression in Rat Brain: Evidence Against a Pervasive Relationship of Urocortin‐Containing Projections With Targets Bearing Type 2 CRF Receptors

  1999cited by this paper
• Feeding and body-weight regulation by hypothalamic neuropeptides--mediation of the actions of leptin.

  1999cited by this paper
• Receptor binding, behavioral, and electrophysiological profiles of nonpeptide corticotropin-releasing factor subtype 1 receptor antagonists CRA1000 and CRA1001.

  1999cited by this paper
• Stress-induced behaviors require the corticotropin-releasing hormone (CRH) receptor, but not CRH.

  1999cited by this paper
• Printed in U.S.A. Copyright © 2000 by The Endocrine Society Modulation of Urocortin-Induced Hypophagia and Weight Loss by Corticotropin-Releasing Factor Receptor 1 Deficiency in Mice*

  1999cited by this paper
• Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development.

  1998cited by this paper
• Hypothalamic corticotropin-releasing hormone is a mediator of the anorexigenic effect of leptin.

  1998cited by this paper
• Altered expression of type 2 CRH receptor mRNA in the VMH by glucocorticoids and starvation.

  1998cited by this paper
• Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1

  1998cited by this paper
• Effect of urocortin on ACTH secretion from rat anterior pituitary in vitro and in vivo: comparison with corticotropin-releasing hormone.

  1998cited by this paper
• Urocortin, a newly identified corticotropin-releasing factor-related mammalian peptide, stimulates atrial natriuretic peptide and brain natriuretic peptide secretions from neonatal rat cardiomyocytes.

  1998cited by this paper
• Altered expression of type 2 CRH receptor mRNA in the VMH by glucocorticoids and starvation.

  1998cited by this paper
• Central administration of urocortin inhibits vasopressin release in conscious rats.

  1998cited by this paper
• The role of CRF2 receptors in corticotropin‐releasing factor‐and urocortin‐induced anorexia

  1998cited by this paper
• Type 2 corticotropin-releasing hormone receptor mRNA expression in the heart in hypertensive rats.

  1998cited by this paper
• Leptin affects food intake via CRF-receptor-mediated pathways

  1998cited by this paper
• Neuroendocrine Responses to Starvation and Weight Loss

  1997cited by this paper
• A new functional isoform of the human CRF2 receptor for corticotropin-releasing factor.

  1997cited by this paper
• Corticotropin-releasing Factor and Adrenocorticotrophic Hormone as Potential Central Mediators of OB Effects*

  1997cited by this paper
• Differential regulation of type-1 and type-2alpha corticotropin-releasing hormone receptor mRNA in the hypothalamic paraventricular nucleus of the rat.

  1997cited by this paper
• Leptin inhibition of the hypothalamic-pituitary-adrenal axis in response to stress.

  1997cited by this paper
• Cardiac inotropic actions of urocortin in conscious sheep.

  1997cited by this paper
• Seminars in medicine of the Beth Israel Deaconess Medical Center. Neuroendocrine responses to starvation and weight loss.

  1997cited by this paper
• Functional activation of CRH neurons and expression of the genes encoding CRH and its receptors in food-deprived lean (Fa/?) and obese (fa/fa) Zucker rats.

  1997cited by this paper
• Stimulation of corticotrophin‐releasing hormone release by the obese (ob) gene product, leptin, from hypothalamic explants

  1997cited by this paper
• Endotoxin regulates corticotropin-releasing hormone receptor 2 in heart and skeletal muscle.

  1997cited by this paper
• Localization of urocortin messenger RNA in rat brain and pituitary.

  1996cited by this paper
• Cloning and characterization of human urocortin.

  1996cited by this paper
• Appetite-Suppressing Effects of Urocortin, a CRF-Related Neuropeptide

  1996cited by this paper
• Cloning and characterization of the human corticotropin-releasing factor-2 receptor complementary deoxyribonucleic acid.

  1996cited by this paper
• Identification of targets of leptin action in rat hypothalamus.

  1996cited by this paper
• CP-154,526: a potent and selective nonpeptide antagonist of corticotropin releasing factor receptors.

  1996cited by this paper
• Expression of corticotropin-releasing factor and its receptors in the brain of lean and obese Zucker rats.

  1996cited by this paper
• Cardiac and behavioral responses of long-term obese and lean Zucker rats to emotional stress.

  1995cited by this paper
• CRF2 alpha and CRF2 beta receptor mRNAs are differentially distributed between the rat central nervous system and peripheral tissues.

  1995cited by this paper
• Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor

  1995cited by this paper
• Identification of a second corticotropin-releasing factor receptor gene and characterization of a cDNA expressed in heart.

  1995cited by this paper
• Chronic infusion of a CRH1 receptor antisense oligodeoxynucleotide into the central nucleus of the amygdala reduced anxiety-related behavior in socially defeated rats.

  1995cited by this paper
• Cloning and characterization of a functionally distinct corticotropin-releasing factor receptor subtype from rat brain.

  1995cited by this paper
• Localization of corticotropin-releasing hormone (CRH) receptor mRNA in adult rat brain by in situ hybridization histochemistry.

  1994cited by this paper
• Cloning and functional expression of a rat brain corticotropin releasing factor (CRF) receptor.

  1993cited by this paper
• Endogenous corticotropin-releasing factor modulates feeding induced by neuropeptide Y or a tail-pinch stressor.

  1992cited by this paper
• Central regulation of stress responses: regulation of the autonomic nervous system and visceral function by corticotrophin releasing factor-41.

  1991cited by this paper
• Hypothalamic food intake regulating areas are involved in the homeostasis of blood glucose and plasma FFA levels.

  1988cited by this paper
• Corticotropin-releasing factor receptor antagonist: effects on the autonomic nervous system and cardiovascular function.

  1986cited by this paper
• Organization of ovine corticotropin-releasing factor immunoreactive cells and fibers in the rat brain: an immunohistochemical study.

  1983cited by this paper
• Corticotropin-releasing factor: actions on the sympathetic nervous system and metabolism.

  1982cited by this paper
• Printed in U.S.A. Copyright © 1999 by The Endocrine Society The Impact of the Nonpeptide Corticotropin-Releasing Hormone Antagonist Antalarmin on Behavioral and Endocrine Responses to Stress*

  year unknowncited by this paper

• Unlocking the potential: How acupuncture reshapes the liver-centered lipid metabolism pattern to fight obesity.

  2024cites this paper
• The Caudal Neurosecretory System: A Still Enigmatic Second Neuroendocrine Complex in Fish

  2024cites this paper
• Mental Stress and Its Effects on Vascular Health

  2022cites this paper
• Pharmacological Evaluation of a Pegylated Urocortin-1 Peptide in Experimental Autoimmune Disease Models

  2022cites this paper
• Effects of Psychological Stress on Vascular Physiology: Beyond the Current Imaging Signal

  2020cites this paper
• Leptin in teleost fish Marloes Vissers ,

  2019cites this paper
• Natural and synthetic peptides in the cardiovascular diseases: An update on diagnostic and therapeutic potentials.

  2019cites this paper
• Epigenetic Programming of Synthesis, Release, and/or Receptor Expression of Common Mediators Participating in the Risk/Resilience for Comorbid Stress-Related Disorders and Coronary Artery Disease

  2018cites this paper
• Urocortins: Actions in health and heart failure.

  2017cites this paper
• The Role of Corticotropin-Releasing Hormone-Binding Protein in Binge Drinking and Alcohol Dependence

  2017cites this paper
• Nesfatin-1 influences the excitability of gastric distension-responsive neurons in the ventromedial hypothalamic nucleus of rats.

  2017cites this paper
• Altered functionality of the corticotrophin-releasing hormone receptor-2 in the hypothalamic paraventricular nucleus of hyperphagic maternally separated rats.

  2017cites this paper
• High-Sensitivity Sandwich ELISA for Plasma NT-proUcn2: Plasma Concentrations and Relationship to Mortality in Heart Failure.

  2016cites this paper
• Sex and estrogen affect the distribution of urocortin-1 immunoreactivity in brainstem autonomic nuclei of the rat.

  2015cites this paper
• Female protection from slow‐pressor effects of angiotensin II involves prevention of ROS production independent of NMDA receptor trafficking in hypothalamic neurons expressing angiotensin 1A receptors

  2015cites this paper
• Evidence for the role of corticotropin-releasing factor in major depressive disorder.

  2015influential citation
• Increased anxiety in corticotropin-releasing factor type 2 receptor-null mice requires recent acute stress exposure and is associated with dysregulated serotonergic activity in limbic brain areas

  2014cites this paper
• Edinburgh Research Explorer Increased anxiety in corticotropin-releasing factor type 2 receptor-null mice requires recent acute stress exposure and is associated with dysregulated serotonergic activity in limbic brain areas

  2014cites this paper
• Chapter 194 – Urocortins

  2013cites this paper
• Central urocortin 3 and type 2 corticotropin-releasing factor receptor in the regulation of energy homeostasis: critical involvement of the ventromedial hypothalamus

  2013cites this paper
• Exaggerated anorexigenic response to restraint stress in A(y) mice is associated with elevated CRFR2 mRNA expression in the hypothalamus.

  2013cites this paper
• Mechanisms of cardiovascular actions of urocortins in the hypothalamic arcuate nucleus of the rat.

  2013cites this paper
• Effects of Stresscopin on Rat Hypothalamic Paraventricular Nucleus Neurons In Vitro

  2013cites this paper
• Abrogation of Anthracycline and Ischemia-Reperfusion Induced Injury by Cell Signaling Modulators

  2013cites this paper
• Hormones, 2. Peptides and Proteins: Hypothalamic–Pituitary and Calcitropic Hormones

  2013cites this paper
• Novel Management of Heart Failure

  2013cites this paper
• CRF system and mood disorders.

  2013cites this paper
• Role of NUCB2/Nesfatin-1 in the Hypothalamic Control of Energy Homeostasis

  2013cites this paper
• Hypothalamic expression of urocortin 3 and the type 2 corticotropin-releasing factor receptor is regulated according to feeding state in lean but not obese Zucker rats.

  2012cites this paper
• Effects of Corticotropin-Releasing Factor 1 Receptor Antagonism on the Hypothalamic-Pituitary-Adrenal Axis of Rodents

  2012cites this paper
• Urocortins and CRF type 2 receptor isoforms expression in the rat stomach are regulated by endotoxin: role in the modulation of delayed gastric emptying.

  2012cites this paper
• Activation of corticotropin releasing factor receptor type 2 in the heart by corticotropin releasing factor offers cytoprotection against ischemic injury via PKA and PKC dependent signaling.

  2012cites this paper
• regulated by endotoxin: role in the modulation of delayed gastric emptying

  2012cites this paper
• Splicing and Multiple Binding Proteins in the Corticotropin-Releasing Hormone Stress System.

  2011cites this paper
• Prolonged Urocortin 2 Administration in Experimental Heart Failure: Sustained Hemodynamic, Endocrine, and Renal Effects

  2011cites this paper
• Reduction of high-fat diet-induced obesity after chronic administration of brain-derived neurotrophic factor in the hypothalamic ventromedial nucleus.

  2011cites this paper
• Molecular signaling and translational significance of the corticotropin releasing factor system.

  2011cites this paper
• Corticotropin-releasing factor signaling and visceral response to stress

  2010cites this paper
• Corticotropin-releasing hormone receptor-1 in cerebral microvessels changes during development and influences urocortin transport across the blood-brain barrier.

  2010cites this paper
• Neuroendocrine mechanisms in pregnancy and parturition.

  2010cites this paper
• Male and female odors induce Fos expression in chemically defined neuronal population.

  2010cites this paper
• The CRF system, stress, depression and anxiety—insights from human genetic studies

  2010cites this paper
• Leptin in Teleost Fish

  2010cites this paper
• Participation of corticotropin-releasing factor type 2 receptors in the acute, chronic and withdrawal actions of nicotine associated with feeding behavior in rats.

  2009cites this paper
• A novel corticotropin‐releasing factor receptor splice variant exhibits dominant negative activity: a putative link to stress‐induced heart disease

  2009cites this paper
• Novel expression of type 1 corticotropin-releasing hormone receptor in multiple endocrine cell types in the murine anterior pituitary.

  2009cites this paper
• Rôle du thalamus médian dorsal dans la régulation de l'axe hypophyso-cortico-surrénalien et le comportement alimentaire

  2008cites this paper
• Urocortin and the brain.

  2008cites this paper
• Abbreviated title: Novel pituitary CRH-R1 expression

  2008cites this paper
• Hormone-dependent gynaecological disorders: a pathophysiological perspective for appropriate treatment.

  2008cites this paper
• Emerging Anxiolytics: Corticotropin‐Releasing Factor Receptor Antagonists

  2007cites this paper
• Delayed Satiety-Like Actions and Altered Feeding Microstructure by a Selective Type 2 Corticotropin-Releasing Factor Agonist in Rats: Intra-Hypothalamic Urocortin 3 Administration Reduces Food Intake by Prolonging the Post-Meal Interval

  2007cites this paper
• Physiology, pharmacology, and therapeutic relevance of urocortins in mammals: ancient CRF paralogs.

  2007cites this paper
• A Comparison between the Cardiovascular Actions of Urocortin 1 and Urocortin 2 (Stresscopin-Related Peptide) in Conscious Rats

  2007cites this paper
• Emerging drugs for eating disorder treatment

  2006cites this paper
• Cardiovascular actions of the stress-related neurohormonal peptides, corticotropin-releasing factor and urotensin-I in the trout Oncorhynchus mykiss.

  2006cites this paper
• Distribution of urocortin 3 neurons innervating the ventral premammillary nucleus in the rat brain.

  2006cites this paper
• Central Pharmacological Targets

  2005cites this paper
• Urocortins of the South African clawed frog, Xenopus laevis: conservation of structure and function in tetrapod evolution.

  2005cites this paper
• 1 Hormones in the Physiology and Pharmacology of Pregnancy The Neuroendocrinology of Pregnancy

  year unknowncites this paper