Representation of continuous hand and arm movements in macaque areas M1, F5, and AIP: a comparative decoding study

Objective. In the last decade, multiple brain areas have been investigated with respect to their decoding capability of continuous arm or hand movements. So far, these studies have mainly focused on motor or premotor areas like M1 and F5. However, there is accumulating evidence that anterior intraparietal area (AIP) in the parietal cortex also contains information about continuous movement. Approach. In this study, we decoded 27 degrees of freedom representing complete hand and arm kinematics during a delayed grasping task from simultaneously recorded activity in areas M1, F5, and AIP of two macaque monkeys (Macaca mulatta). Main results. We found that all three areas provided decoding performances that lay significantly above chance. In particular, M1 yielded highest decoding accuracy followed by F5 and AIP. Furthermore, we provide support for the notion that AIP does not only code categorical visual features of objects to be grasped, but also contains a substantial amount of temporal kinematic information. Significance. This fact could be utilized in future developments of neural interfaces restoring hand and arm movements.

• Publication year

  2015

• Venue

  Journal of Neural Engineering

• Publication date

  2015-09-11

• Fields of study

  Biology, Medicine, Physics, Psychology

• Identifiers
  DOI 10.1088/1741-2560/12/5/056016PMID 26355718
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Continuous detection and prediction of grasp states and kinematics from primate motor, premotor, and parietal cortex

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• Musculoskeletal Representation of a Large Repertoire of Hand Grasping Actions in Primates

  2015influential reference
• Decoding a Wide Range of Hand Configurations from Macaque Motor, Premotor, and Parietal Cortices

  2015cited by this paper
• Decoding motor imagery from the posterior parietal cortex of a tetraplegic human

  2015cited by this paper
• Closed-loop decoder adaptation shapes neural plasticity for skillful neuroprosthetic control.

  2014cited by this paper
• Reach and Gaze Representations in Macaque Parietal and Premotor Grasp Areas

  2013cited by this paper
• High-performance neuroprosthetic control by an individual with tetraplegia.

  2013cited by this paper
• State-based decoding of hand and finger kinematics using neuronal ensemble and LFP activity during dexterous reach-to-grasp movements.

  2013influential reference
• Reach and grasp by people with tetraplegia using a neurally controlled robotic arm

  2012cited by this paper
• Cognitive signals for brain–machine interfaces in posterior parietal cortex include continuous 3D trajectory commands

  2012cited by this paper
• Decoding 3D reach and grasp from hybrid signals in motor and premotor cortices: spikes, multiunit activity, and local field potentials.

  2012cited by this paper
• A new method of accurate hand- and arm-tracking for small primates

  2012influential reference
• Grasp Movement Decoding from Premotor and Parietal Cortex

  2011influential reference
• Relationships among low-frequency local field potentials, spiking activity, and three-dimensional reach and grasp kinematics in primary motor and ventral premotor cortices.

  2011cited by this paper
• Decoding Complete Reach and Grasp Actions from Local Primary Motor Cortex Populations

  2010influential reference
• Context-Specific Grasp Movement Representation in Macaque Ventral Premotor Cortex

  2010cited by this paper
• Projections of the hand field of the macaque ventral premotor area F5 to the brainstem and spinal cord

  2010cited by this paper
• Multimodal architectonic subdivision of the rostral part (area F5) of the macaque ventral premotor cortex

  2009cited by this paper
• Context-Specific Grasp Movement Representation in the Macaque Anterior Intraparietal Area

  2009cited by this paper
• Subdivisions of primary motor cortex based on cortico-motoneuronal cells

  2009cited by this paper
• Cortical control of a prosthetic arm for self-feeding

  2008cited by this paper
• Cortical connections of the macaque anterior intraparietal (AIP) area.

  2008cited by this paper
• Forward estimation of movement state in posterior parietal cortex

  2008cited by this paper
• Decoding M1 neurons during multiple finger movements.

  2007influential reference
• Encoding of reach and grasp by single neurons in premotor cortex is independent of recording site.

  2007cited by this paper
• Simultaneous recording of macaque premotor and primary motor cortex neuronal populations reveals different functional contributions to visuomotor grasp.

  2007influential reference
• Functional properties of grasping-related neurons in the ventral premotor area F5 of the macaque monkey.

  2006cited by this paper
• Assesment of metallic distortions of an electromagnetic tracking system

  2006cited by this paper
• Bayesian Population Decoding of Motor Cortical Activity Using a Kalman Filter

  2006cited by this paper
• Muscle representation in the macaque motor cortex: an anatomical perspective.

  2006cited by this paper
• Cortical Ensemble Adaptation to Represent Velocity of an Artificial Actuator Controlled by a Brain-Machine Interface

  2005cited by this paper
• Frontal Lobe Inputs to the Digit Representations of the Motor Areas on the Lateral Surface of the Hemisphere

  2005cited by this paper
• Coding and transmission of information by neural ensembles.

  2004cited by this paper
• Targeting Recovery: Priorities of the Spinal Cord-Injured Population

  2004cited by this paper
• Functional properties of grasping-related neurons in the dorsal premotor area F2 of the macaque monkey.

  2004cited by this paper
• On the relations between single cell activity in the motor cortex and the direction and magnitude of three-dimensional static isometric force

  2004cited by this paper
• Neurons related to goal-directed motor acts in inferior area 6 of the macaque monkey

  2004cited by this paper
• Unsupervised Spike Detection and Sorting with Wavelets and Superparamagnetic Clustering

  2004cited by this paper
• Functional organization of inferior area 6 in the macaque monkey

  2004cited by this paper
• Closed-loop neural control of cursor motion using a Kalman filter

  2004cited by this paper
• Guidelines for the care and use of mammals in neuroscience and behavioral research

  2003cited by this paper
• Prediction of muscle activity by populations of sequentially recorded primary motor cortex neurons.

  2003cited by this paper
• Learning to Control a Brain–Machine Interface for Reaching and Grasping by Primates

  2003cited by this paper
• Primary motor cortical neurons encode functional muscle synergies

  2002cited by this paper
• Comparison of neuronal firing rates in somatosensory and posterior parietal cortex during prehension

  2001cited by this paper
• Direction of action is represented in the ventral premotor cortex

  2001cited by this paper
• The cortical motor system.

  2001cited by this paper
• Cortical mechanism for the visual guidance of hand grasping movements in the monkey: A reversible inactivation study.

  2001cited by this paper
• Selectivity for the shape, size, and orientation of objects for grasping in neurons of monkey parietal area AIP.

  2000cited by this paper
• Real-time prediction of hand trajectory by ensembles of cortical neurons in primates

  2000cited by this paper
• Limited functional grouping of neurons in the motor cortex hand area during individuated finger movements: A cluster analysis.

  1999cited by this paper
• Facilitation of neuronal activity in somatosensory and posterior parietal cortex during prehension

  1999cited by this paper
• Neural representation of three-dimensional features of manipulation objects with stereopsis

  1999cited by this paper
• Muscle and movement representations in the primary motor cortex.

  1999cited by this paper
• Corticomotoneuronal postspike effects in shoulder, elbow, wrist, digit, and intrinsic hand muscles during a reach and prehension task.

  1998cited by this paper
• Force and the motor cortex.

  1997cited by this paper
• The TINS Lecture. The parietal association cortex in depth perception and visual control of hand action.

  1997cited by this paper
• Object representation in the ventral premotor cortex (area F5) of the monkey.

  1997influential reference
• Erratum to “Force and the motor cortex”: [Behavioural Brain Research 86 (1997) 1–15]1

  1997cited by this paper
• Corticomotoneuronal contribution to the fractionation of muscle activity during precision grip in the monkey.

  1996cited by this paper
• Grasping objects: the cortical mechanisms of visuomotor transformation.

  1995cited by this paper
• Neural mechanisms of visual guidance of hand action in the parietal cortex of the monkey.

  1995cited by this paper
• Multiple corticospinal neuron populations in the macaque monkey are specified by their unique cortical origins, spinal terminations, and connections.

  1994cited by this paper
• Deficit of hand preshaping after muscimol injection in monkey parietal cortex

  1994cited by this paper
• Welch & Bishop , An Introduction to the Kalman Filter 2 1 The Discrete Kalman Filter In 1960

  1994cited by this paper
• Movement parameters and neural activity in motor cortex and area 5.

  1994cited by this paper
• Topographic organization of corticospinal projections from the frontal lobe: motor areas on the lateral surface of the hemisphere

  1993cited by this paper
• Functional organization of inferior area 6 in the macaque monkey

  1988cited by this paper
• Neuronal population coding of movement direction.

  1986cited by this paper
• Corticospinal facilitation of hand muscles during voluntary movement in the conscious monkey.

  1986cited by this paper
• Modeling manufacturing grips and correlations with the design of robotic hands

  1986cited by this paper
• Afferent and efferent projections of the inferior area 6 in the macaque monkey

  1986cited by this paper
• Characteristics of corticomotoneuronal postspike facilitation and reciprocal suppression of EMG activity in the monkey.

  1985cited by this paper
• Functional classes of primate corticomotoneuronal cells and their relation to active force.

  1980cited by this paper
• Postspike facilitation of forelimb muscle activity by primate corticomotoneuronal cells.

  1980cited by this paper
• Frontal lobe inputs to primate motor cortex: evidence for four somatotopically organized 'premotor' areas.

  1979cited by this paper
• Magnetic Position and Orientation Tracking System

  1979cited by this paper
• Correlation of neural discharge with pattern and force of muscular activity, joint position, and direction of intended next movement in motor cortex and cerebellum.

  1978influential reference
• Effects of posterior parietal lesions on visually guided behavior in monkeys.

  1978cited by this paper
• A new approach to linear filtering and prediction problems" transaction of the asme~journal of basic

  1960cited by this paper
• A New Approach to Linear Filtering and Prediction Problems

  year unknowncited by this paper
• Decoding 3-d Reach and Grasp from Hybrid Signals in Motor and Premotor Cortices: Spikes, Multiunit Activity and Local Field Potentials

  year unknowncited by this paper

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• Spatio-temporal transformers for decoding neural movement control

  2024cites this paper
• The macaque ventral intraparietal functional connectivity patterns reveal an anterio-posterior specialization mirroring that described in human ventral intraparietal area

  2024cites this paper
• Accurate neural control of a hand prosthesis by posture-related activity in the primate grasping circuit

  2024influential citation
• Robust cortical encoding of 3D tongue shape during feeding in macaques

  2023cites this paper
• Deep Learning for Real-Time Neural Decoding of Grasp

  2023cites this paper
• Information-processing dynamics in neural networks of macaque cerebral cortex reflect cognitive state and behavior

  2021cites this paper
• The macaque ventral intraparietal area has expanded into three homologue human parietal areas.

  2021cites this paper
• Evolution of Parietal Cortex in Mammals: From Manipulation to Tool Use

  2020cites this paper
• Modeling behaviorally relevant neural dynamics enabled by preferential subspace identification

  2020cites this paper
• Unexpected complexity of everyday manual behaviors

  2019cites this paper
• Decoding hand kinematics from population responses in sensorimotor cortex during grasping

  2019influential citation
• Neural population dynamics in motor cortex are different for reach and grasp

  2019cites this paper
• State Estimation in Posterior Parietal Cortex: Distinct Poles of Environmental and Bodily States.

  2019cites this paper
• Biomechatronics: Harmonizing Mechatronic Systems with Human Beings

  2019cites this paper
• Enhancing gesture decoding performance using signals from posterior parietal cortex: a stereo-electroencephalograhy (SEEG) study

  2019cites this paper
• Single-Finger Neural Basis Information-Based Neural Decoder for Multi-Finger Movements

  2018cites this paper
• Cortical Decoding of Individual Finger Group Motions Using ReFIT Kalman Filter

  2018cites this paper
• Peripheral nervous system control for neuroprostheses

  2017cites this paper
• Stability of recording and neural tuning during intracortical brain-computer interface arm control

  2017cites this paper
• Decoding Lower Limb Muscle Activity and Kinematics from Cortical Neural Spike Trains during Monkey Performing Stand and Squat Movements

  2017cites this paper
• Encoding, coordination, and decision making in the primate fronto-parietal grasping network

  2017cites this paper
• Real-Time Decoding of Arm Kinematics During Grasping Based on F5 Neural Spike Data

  2017cites this paper
• Neural Dynamics of Variable Grasp-Movement Preparation in the Macaque Frontoparietal Network

  2017cites this paper
• Motor cortical activity changes during neuroprosthetic-controlled object interaction

  2017cites this paper
• Neural control of finger movement via intracortical brain–machine interface

  2017cites this paper
• Continuous detection and prediction of grasp states and kinematics from primate motor, premotor, and parietal cortex

  2015cites this paper