Kim et al. identify a novel shear stress–induced pathway involving protein kinase A, CREB, and bone morphogenetic protein that regulates hematopoietic stem cell generation in the embryonic aorta.
Flow-induced protein kinase A–CREB pathway acts via BMP signaling to promote HSC emergence
P. Kim,H. Nakano,Partha P. Das,Michael J. Chen,R. G. Rowe,Stephanie S. Chou,Samantha Ross,K. Sakamoto,L. Zon,T. Schlaeger,Stuart H. Orkin,A. Nakano,G. Daley
Published 2015 in Journal of Experimental Medicine
ABSTRACT
PUBLICATION RECORD
- Publication year
2015
- Venue
Journal of Experimental Medicine
- Publication date
2015-04-27
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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