H19 mediates methotrexate resistance in colorectal cancer through activating Wnt/&bgr;‐catenin pathway

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Experimental Cell Research

• Publication date

  2017-01-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.yexcr.2016.12.003PMID 27919747
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2015cited by this paper
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  2015cited by this paper
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  2015cited by this paper
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  2014cited by this paper
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  2011cited by this paper
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  2011cited by this paper
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  2011cited by this paper
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  2011cited by this paper
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  2010cited by this paper
• Long noncoding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

  2010cited by this paper
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  2010cited by this paper
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  2009cited by this paper
• Long non-coding RNAs: insights into functions

  2009cited by this paper
• The H19 Non-Coding RNA Is Essential for Human Tumor Growth

  2007cited by this paper
• Riboregulator H19 induction of MDR1-associated drug resistance in human hepatocellular carcinoma cells

  2007cited by this paper
• [Systemic therapy for colorectal cancer].

  2005cited by this paper
• H19 mRNA-like Noncoding RNA Promotes Breast Cancer Cell Proliferation through Positive Control by E2F1*

  2005cited by this paper
• Global Cancer Statistics, 2002

  2005cited by this paper
• Systemic therapy for colorectal cancer.

  2005cited by this paper
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  2000cited by this paper
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  1998cited by this paper
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  1996cited by this paper
• New concepts for the development and use of antifolates.

  1996cited by this paper
• Loss of H19 imprinting in esophageal cancer.

  1996cited by this paper
• New Concepts for the Development and Use of Antifolates

  1996cited by this paper
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  1995cited by this paper
• Tumour-suppressor activity of H19 RNA

  1993cited by this paper
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  1993cited by this paper
• Glucose starvation and acidosis: effect on experimental metastatic potential, DNA content and MTX resistance of murine tumour cells.

  1991cited by this paper
• Dihydrofolate reductase as a therapeutic target

  1990cited by this paper
• Gene amplification in cultured cells.

  1988cited by this paper
• The functional human dihydrofolate reductase gene.

  1984cited by this paper

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  2023cites this paper
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  2022cites this paper
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  2022cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2017cites this paper