TRPC5 is a regulator of hippocampal neurite length and growth cone morphology

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Nature Neuroscience

• Publication date

  2003-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/nn1092PMID 12858178
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Lanthanides Potentiate TRPC5 Currents by an Action at Extracellular Sites Close to the Pore Mouth*

  2003cited by this paper
• Subunit composition of mammalian transient receptor potential channels in living cells

  2002cited by this paper
• The oncoprotein 18/stathmin family of microtubule destabilizers.

  2002cited by this paper
• SNARE-mediated membrane fusion

  2001cited by this paper
• LTRPC7 is a Mg·ATP-regulated divalent cation channel required for cell viability

  2001cited by this paper
• The cell biology of neuronal navigation

  2001cited by this paper
• TRPC1 and TRPC5 form a novel cation channel in mammalian brain.

  2001cited by this paper
• Filopodial Calcium Transients Promote Substrate-Dependent Growth Cone Turning

  2001cited by this paper
• The trp ion channel family

  2001cited by this paper
• Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation.

  2001cited by this paper
• Calcium, Calcineurin, and the Control of Transcription*

  2001cited by this paper
• Cortactin: coupling membrane dynamics to cortical actin assembly

  2001cited by this paper
• TRP-PLIK, a Bifunctional Protein with Kinase and Ion Channel Activities

  2001cited by this paper
• The versatility and universality of calcium signalling

  2000cited by this paper
• Coding of neuronal differentiation by calcium transients

  2000cited by this paper
• Receptor-mediated Regulation of the Nonselective Cation Channels TRPC4 and TRPC5*

  2000cited by this paper
• From worm to man: three subfamilies of TRP channels.

  2000cited by this paper
• Assembly of presynaptic active zones from cytoplasmic transport packets

  2000cited by this paper
• Localization and targeting of SCG10 to the trans‐Golgi apparatus and growth cone vesicles

  2000cited by this paper
• In vivo regulation of axon extension and pathfinding by growth-cone calcium transients

  1999cited by this paper
• Molecular and Functional Characterization of a Novel Mouse Transient Receptor Potential Protein Homologue TRP7

  1999cited by this paper
• Translocation of cortactin to the cell periphery is mediated by the small GTPase Rac1.

  1998cited by this paper
• Identification of a Novel Cortactin SH3 Domain-Binding Protein and Its Localization to Growth Cones of Cultured Neurons

  1998cited by this paper
• Visualization of the Dynamics of Synaptic Vesicle and Plasma Membrane Proteins in Living Axons

  1998cited by this paper
• Rac1-dependent actin filament organization in growth cones is necessary for beta1-integrin-mediated advance but not for growth on poly-D-lysine.

  1998cited by this paper
• Semaphorins A and E act as antagonists of neuropilin-1 and agonists of neuropilin-2 receptors

  1998cited by this paper
• Molecular Cloning and Functional Characterization of a Novel Receptor-activated TRP Ca2+ Channel from Mouse Brain*

  1998cited by this paper
• Neuronal calcium signaling.

  1998cited by this paper
• SCLIP: A Novel SCG10‐Like Protein of the Stathmin Family Expressed in the Nervous System

  1998cited by this paper
• The stathmin phosphoprotein family: intracellular localization and effects on the microtubule network.

  1998cited by this paper
• Evidence for Direct Physical Association between a K+Channel (Kir6.2) and an ATP-Binding Cassette Protein (SUR1) Which Affects Cellular Distribution and Kinetic Behavior of an ATP-Sensitive K+ Channel

  1998cited by this paper
• Purification, characterization, and in vitro phosphorylation of the neuron-specific membrane-associated protein SCG10.

  1997cited by this paper
• The stathmin family -- molecular and biological characterization of novel mammalian proteins expressed in the nervous system.

  1997cited by this paper
• Identification of a protein that interacts with tubulin dimers and increases the catastrophe rate of microtubules.

  1996cited by this paper
• Distinct aspects of neuronal differentiation encoded by frequency of spontaneous Ca2+ transients

  1995cited by this paper
• Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33

  1995cited by this paper
• Experimental observations on the development of polarity by hippocampal neurons in culture

  1989cited by this paper
• The NGF-inducible SCG10 mRNA encodes a novel membrane-bound protein present in growth cones and abundant in developing neurons.

  1988cited by this paper
• Early differentiation of vertebrate spinal neurons in the absence of voltage-dependent Ca2+ and Na+ influx.

  1984cited by this paper
• An electron microscopic study of the development of axons and dendrites by hippocampal neurons in culture. I. Cells which develop without intercellular contacts

  1984cited by this paper

• Identification and expression of transient receptor potential (TRP) genes in Urechis unicinctus and the role of TRPC5 in immune response.

  2026cites this paper
• Transient Receptor Potential channels (TRP) in GtoPdb v.2025.4

  2025cites this paper
• Structure–Function Diversity of Calcium-Binding Proteins (CaBPs): Key Roles in Cell Signalling and Disease

  2025cites this paper
• Thermo‐TRP regulation by endogenous factors and its physiological function at core body temperature

  2025cites this paper
• The Role of Ion Channels in the Development of the Nervous System

  2025cites this paper
• TRPC1 and TRPC5 in Colorectal Cancer: Mechanisms, Prognostic Markers, and Therapeutic Targets

  2025cites this paper
• Physiological functions and pharmacological targeting of transient receptor potential channels

  2025cites this paper
• Molecular architecture of the human TRPC1/C5 heteromeric channel

  2025cites this paper
• The odyssey of the TR(i)P journey to the cellular membrane

  2024cites this paper
• Microtubules, Membranes, and Movement: New Roles for Stathmin‐2 in Axon Integrity

  2024cites this paper
• Effects of TRPC1’s Lysines on Heteromeric TRPC5-TRPC1 Channel Function

  2024cites this paper
• Multi-omics combined to investigate potential druggable therapeutic targets for stroke: A systematic Mendelian randomization study and transcriptome verification.

  2024cites this paper
• The TRPC5 receptor as pharmacological target for pain and metabolic disease.

  2024cites this paper
• Mechanosensitive ion channels in glaucoma pathophysiology.

  2024cites this paper
• Transient Receptor Potential Channels in the Healthy and Diseased Blood–Brain Barrier

  2024cites this paper
• Selective Assembly of TRPC Channels in the Rat Retina during Photoreceptor Degeneration

  2024cites this paper
• Direct modulation of TRPC ion channels by Gα proteins

  2024cites this paper
• The small GTPase regulatory protein Rac1 drives podocyte injury independent of cationic channel protein TRPC5.

  2023cites this paper
• TRP Channels in Stroke

  2023cites this paper
• The SphK1/S1P Axis Regulates Synaptic Vesicle Endocytosis via TRPC5 Channels

  2023cites this paper
• Pathophysiological Roles of Transient Receptor Potential (Trp) Channels and Zinc Toxicity in Brain Disease

  2023cites this paper
• Amphetamines abuse and depression: Focus on TRPC channels.

  2023cites this paper
• Genome-wide association study identi fi es SESTD1 as a novel risk gene for lithium-responsive bipolar disorder

  2023cites this paper
• “ThermoTRP” Channel Expression in Cancers: Implications for Diagnosis and Prognosis (Practical Approach by a Pathologist)

  2023cites this paper
• Exendin-4 Increases the Firing Activity of Hippocampal CA1 Neurons Through TRPC4/5 channels.

  2023cites this paper
• The Roles of Transient Receptor Potential Ion Channels in Pathologies of Glaucoma

  2022cites this paper
• Synthesis of AC1903 analogs as potent transient receptor potential canonical channel 4/5 inhibitors and biological evaluation.

  2022cites this paper
• Interactions between the Polysialylated Neural Cell Adhesion Molecule and the Transient Receptor Potential Canonical Channels 1, 4, and 5 Induce Entry of Ca2+ into Neurons

  2022cites this paper
• Blockade of TRPC Channels Limits Cholinergic-Driven Hyperexcitability and Seizure Susceptibility After Traumatic Brain Injury

  2021cites this paper
• Evaluation of podocyte Rac-1 induced kidney disease by modulation of TRPC5

  2021cites this paper
• The Role of Thermosensitive Ion Channels in Mammalian Thermoregulation.

  2021cites this paper
• Novel localizations of TRPC5 channels suggest novel and unexplored roles: A study in the chick embryo brain

  2021cites this paper
• Upregulation of TRPC5 in hippocampal excitatory synapses improves memory impairment associated with neuroinflammation in microglia knockout IL-10 mice

  2021cites this paper
• TRPC5 mediates TMZ resistance in TMZ-resistant glioblastoma cells via NFATc3-P-gp pathway

  2021cites this paper
• Transient Receptor Potential Canonical Channels in Health and Disease: A 2020 Update

  2021cites this paper
• Memory Impairment Related to NLRP3 Inflammasome Activation and TRPC5 Decrease in Hippocampal Excitatory Synapses in Microglia Knockout IL-10 Mice

  2021cites this paper
• Contribution of TRPC Channels in Neuronal Excitotoxicity Associated With Neurodegenerative Disease and Ischemic Stroke

  2021cites this paper
• Role of Oxidative Stress and Ca2+ Signaling in Psychiatric Disorders

  2021cites this paper
• Minireview: Insights into the role of TRP channels in the retinal circulation and function

  2021cites this paper
• What Is the Role of Stathmin-2 in Axonal Biology and Degeneration?

  2021cites this paper
• TRPC1/4/5 channels contribute to morphine‐induced analgesic tolerance and hyperalgesia by enhancing spinal synaptic potentiation and structural plasticity

  2020cites this paper
• Evidence of a Role for the TRPC Subfamily in Mediating Oxidative Stress in Parkinson’s Disease

  2020cites this paper
• Transient Receptor Potential Canonical (TRPC) Channels: Then and Now

  2020cites this paper
• How TRPC Channels Modulate Hippocampal Function

  2020cites this paper
• TRPC channels: Structure, function, regulation and recent advances in small molecular probes.

  2020cites this paper
• Transient Receptor Potential Canonical 5-Scramblase Signaling Complex Mediates Neuronal Phosphatidylserine Externalization and Apoptosis

  2020cites this paper
• TRP Channels Regulation of Rho GTPases in Brain Context and Diseases

  2020cites this paper
• TRPV2 interacts with actin and reorganizes submembranous actin cytoskeleton

  2020cites this paper
• Transient Receptor Potential Canonical (TRPC) Channels as Modulators of Migration and Invasion

  2020cites this paper
• Canonical Transient Receptor Potential (TRPC) Channels in Nociception and Pathological Pain

  2020cites this paper
• The versatile Kv channels in the nervous system: actions beyond action potentials

  2020cites this paper
• TRPC1 Regulates the Activity of a Voltage-Dependent Nonselective Cation Current in Hippocampal CA1 Neurons

  2020cites this paper
• Roles of TRP Channels in Neurological Diseases

  2020cites this paper
• Regulation of TRPC5 currents by intracellular ATP: Single channel studies

  2020cites this paper
• Molecular composition of developing glutamatergic synapses

  2020cites this paper
• TRP Channels and Small GTPases Interplay in the Main Hallmarks of Metastatic Cancer

  2020cites this paper
• TRPC channels regulate Ca2+-signaling and short-term plasticity of fast glutamatergic synapses

  2019cites this paper
• Neuropsychiatric implications of transient receptor potential vanilloid (TRPV) channels in the reward system.

  2019cites this paper
• Trpc5 deficiency causes hypoprolactinemia and altered function of oscillatory dopamine neurons in the arcuate nucleus

  2019cites this paper
• TRPM2 channel regulates cytokines production in astrocytes and aggravates brain disorder during lipopolysaccharide-induced endotoxin sepsis.

  2019cites this paper
• TRPV2 activation reorganizes actin cytoskeleton, induces neurite initiation and branching by altering cAMP levels

  2019cites this paper
• DC and AC magnetic fields increase neurite outgrowth of SH-SY5Y neuroblastoma cells with and without retinoic acid

  2019cites this paper
• Transmembrane insertases and N-glycosylation critically determine synthesis, trafficking, and activity of the nonselective cation channel TRPC6

  2019cites this paper
• Development of a carbon-11 PET radiotracer for imaging TRPC5 in the brain.

  2019cites this paper
• A TR(i)P to Cell Migration: New Roles of TRP Channels in Mechanotransduction and Cancer

  2019cites this paper
• Structure–Function Relationship and Physiological Roles of Transient Receptor Potential Canonical (TRPC) 4 and 5 Channels

  2019cites this paper
• TRPC5 regulates axonal outgrowth in developing retinal ganglion cells

  2019cites this paper
• Effect of SKF-96365 on cardiomyocyte hypertrophy induced by angiotensin II

  2019cites this paper
• TRPC5 channel instability induced by depalmitoylation protects striatal neurons against oxidative stress in Huntington's disease.

  2019cites this paper
• Inhibition of TRPC 6 degradation suppresses ischemic brain damage in rats

  2018cites this paper
• The Effect of Magnetic Fields and Magnetic Nanoparticles on Cell Viability and Neurite Outgrowth of SH-SY5Y neuroblastoma cells

  2018cites this paper
• The Effect of Magnetic Fields and Magnetic Nanoparticles on Cell Viability and Neurite Outgrowth of SH-SY 5 Y neuroblastoma cells

  2018cites this paper
• TRPC5 is required for the NO-dependent increase in dendritic Ca2+ and GABA release from chick retinal amacrine cells.

  2018cites this paper
• Activation of TRPC1 Channel by Metabotropic Glutamate Receptor mGluR5 Modulates Synaptic Plasticity and Spatial Working Memory

  2018cites this paper
• Differential regulation of ion channels function by proteolysis.

  2018cites this paper
• Emerging Roles of Diacylglycerol-Sensitive TRPC4/5 Channels

  2018cites this paper
• Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory

  2017cites this paper
• The Role of TRPC6 in the Neuroprotection of Calycosin Against Cerebral Ischemic Injury

  2017cites this paper
• Activation of Transient Receptor Potential Vanilloid 4 Impairs the Dendritic Arborization of Newborn Neurons in the Hippocampal Dentate Gyrus through the AMPK and Akt Signaling Pathways

  2017influential citation
• Store-Operated Ca²⁺ Entry (SOCE) Pathways

  2017cites this paper
• New Aspects of the Contribution of ER to SOCE Regulation: TRPC Proteins as a Link Between Plasma Membrane Ion Transport and Intracellular Ca2+ Stores.

  2017cites this paper
• TRPC Channels and Neuron Development, Plasticity, and Activities.

  2017cites this paper
• TRPC Channel Downstream Signaling Cascades.

  2017cites this paper
• Erratum: Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder

  2017cites this paper
• A Presynaptic Role for Nitric Oxide at a GABAergic Synapse

  2017cites this paper
• TRPC Channels and Mental Disorders.

  2017cites this paper
• TrpC5 regulates differentiation through the Ca2+/Wnt5a signalling pathway in colorectal cancer.

  2017cites this paper
• A benzothiadiazine derivative and methylprednisolone are novel and selective activators of transient receptor potential canonical 5 (TRPC5) channels.

  2017cites this paper
• TRPC5-induced autophagy promotes drug resistance in breast carcinoma via CaMKKβ/AMPKα/mTOR pathway

  2017cites this paper
• Endothelial TRPV4 dysfunction in a streptozotocin-diabetic Rat Model

  2017cites this paper
• TRPC Channels and Programmed Cell Death.

  2017cites this paper
• Na+ entry through heteromeric TRPC4/C1 channels mediates (−)Englerin A-induced cytotoxicity in synovial sarcoma cells

  2017cites this paper
• Extremely Low-Frequency Electromagnetic Fields Promote In Vitro Neuronal Differentiation and Neurite Outgrowth of Embryonic Neural Stem Cells via Up-Regulating TRPC1

  2016cites this paper
• Regulation of pancreatic β-cell death and cancer cell migration by TPRM2 channels

  2016cites this paper
• Calcium Entry Through Thermosensory Channels.

  2016cites this paper
• Methacholine and PDGF activate store-operated calcium entry in neuronal precursor cells via distinct calcium entry channels

  2016cites this paper
• Calcium-permeable ion channels in the kidney.

  2016cites this paper
• Natural and synthetic flavonoid modulation of TRPC5 channels

  2016cites this paper
• TRPCs/Orai1-dependent Store-Operated Ca 2+ Channels, new targets of aldosterone in cardiomyocytes

  2016cites this paper
• Transient Receptor Potential Canonical (TRPC)/Orai1-dependent Store-operated Ca2+ Channels

  2016cites this paper