Functional interaction of the v-Rel and c-Rel oncoproteins with the TATA-binding protein and association with transcription factor IIB

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Molecular and Cellular Biology

• Publication date

  1993-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/mcb.13.11.6733-6741.1993PMID 8413269PMCID PMC364736
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The viral and cellular Rel oncoproteins induce the differentiation of P19 embryonal carcinoma cells

  1995cited by this paper
• The viral and cellular Rel oncoproteins induce the differentiation of P19 embryonal carcinoma cells.

  1994cited by this paper
• Genetic evidence that an activation domain of GAL4 does not require acidity and may form a β sheet

  1993cited by this paper
• Two novel functions associated with the Rel oncoproteins: DNA replication and cell-specific transcriptional activation.

  1993cited by this paper
• Multiple functional domains of human transcription factor IIB: distinct interactions with two general transcription factors and RNA polymerase II.

  1993cited by this paper
• Direct interaction between the transcriptional activation domain of human p53 and the TATA box-binding protein.

  1993cited by this paper
• The acidic activation domains of the GCN4 and GAL4 proteins are not α helical but form β sheets

  1993cited by this paper
• The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB.

  1993cited by this paper
• Genetic evidence that an activation domain of GAL4 does not require acidity and may form a beta sheet.

  1993cited by this paper
• Structure(?) and function of acidic transcription activators

  1993cited by this paper
• Initiation of transcription by RNA polymerase II: a multi-step process.

  1993cited by this paper
• Interaction between a transcriptional activator and transcription factor IIB in vivo

  1993cited by this paper
• Structure(?) and function of acidic transcription activators.

  1993cited by this paper
• The acidic activation domains of the GCN4 and GAL4 proteins are not alpha helical but form beta sheets.

  1993cited by this paper
• Transformation by the vRel oncoprotein requires sequences carboxy-terminal to the Rel homology domain.

  1993cited by this paper
• Transcriptional activity of rel family proteins.

  1992cited by this paper
• A lymphoid cell-specific nuclear factor containing c-Rel-like proteins preferentially interacts with interleukin-6 kappa B-related motifs whose activities are repressed in lymphoid cells

  1992cited by this paper
• The RxxRxRxxC motif conserved in all Rel/kappa B proteins is essential for the DNA-binding activity and redox regulation of the v-Rel oncoprotein

  1992cited by this paper
• The human cytomegalovirus 80-kilodalton but not the 72-kilodalton immediate-early protein transactivates heterologous promoters in a TATA box-dependent mechanism and interacts directly with TFIID

  1992cited by this paper
• NF-κB and related proteins: Rel/dorsal homologies meet ankyrin-like repeats

  1992cited by this paper
• Advances in RNA polymerase II transcription.

  1992cited by this paper
• NF-kappa B and related proteins: Rel/dorsal homologies meet ankyrin-like repeats.

  1992cited by this paper
• The Rel family: models for transcriptional regulation and oncogenic transformation.

  1992cited by this paper
• Wild-type p53 binds to the TATA-binding protein and represses transcription.

  1992cited by this paper
• Riding high on the TATA box

  1992cited by this paper
• Transcription. Riding high on the TATA box.

  1992cited by this paper
• The v-rel oncogene: insights into the mechanism of transcriptional activation, repression, and transformation

  1992cited by this paper
• A protein kinase-A recognition sequence is structurally linked to transformation by p59v-rel and cytoplasmic retention of p68c-rel

  1991cited by this paper
• Binding of general transcription factor TFIIB to an acidic activating region

  1991cited by this paper
• Adenovirus E1A activation domain binds the basic repeat in the TATA box transcription factor.

  1991cited by this paper
• vRel is an inactive member of the Rel family of transcriptional activating proteins

  1991cited by this paper
• Direct interaction between adenovirus E1A protein and the TATA box binding transcription factor IID.

  1991cited by this paper
• Mechanism of action of an acidic transcriptional activator in vitro.

  1991cited by this paper
• c-rel activates but v-rel suppresses transcription from kappa B sites.

  1991cited by this paper
• Isolation of a rel-related human cDNA that potentially encodes the 65-kD subunit of NF-kappa B.

  1991cited by this paper
• The Zta trans-activator protein stabilizes TFIID association with promoter DNA by direct protein-protein interaction.

  1991cited by this paper
• Cloning of the p50 DNA binding subunit of NF-kappa B: homology to rel and dorsal.

  1990cited by this paper
• Cloning and expression of a chicken c-rel cDNA: unlike p59v-rel, p68c-rel is a cytoplasmic protein in chicken embryo fibroblasts.

  1990cited by this paper
• Differential transcriptional activation by Oct-1 and Oct-2: interdependent activation domains induce Oct-2 phosphorylation.

  1990cited by this paper
• The mouse c-rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain

  1990cited by this paper
• The N-terminal env-derived amino acids of v-rel are required for full transforming activity.

  1990cited by this paper
• The v-rel oncogene encodes a kappa B enhancer binding protein that inhibits NF-kappa B function.

  1990cited by this paper
• Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIID

  1990cited by this paper
• The v-rel oncogene encodes a κB enhancer binding protein that inhibits NF-κB function

  1990cited by this paper
• Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal

  1990cited by this paper
• Oncogenic transformation by vrel requires an amino-terminal activation domain

  1990cited by this paper
• Mechanism of transcriptional activation by Sp1: evidence for coactivators.

  1990cited by this paper
• Transcription activation by the adenovirus E1a protein

  1989cited by this paper
• New retrovirus helper cells with almost no nucleotide sequence homology to retrovirus vectors

  1989cited by this paper
• Synergistic activation and repression of transcription by Drosophila homeobox proteins.

  1989cited by this paper
• p59v-rel, the transforming protein of reticuloendotheliosis virus, is complexed with at least four other proteins in transformed chicken lymphoid cells

  1988cited by this paper
• GAL4-VP16 is an unusually potent transcriptional activator

  1988cited by this paper
• v-rel oncoproteins in the nucleus and in the cytoplasm transform chicken spleen cells

  1988cited by this paper
• High-efficiency transformation of mammalian cells by plasmid DNA.

  1987cited by this paper
• A novel rapid assay for chloramphenicol acetyltransferase gene expression

  1987cited by this paper
• Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells

  1982cited by this paper
• Empirical predictions of protein conformation.

  1978cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper
• c-rel activates but v-rel suppresses transcription from KB sites

  year unknowncited by this paper

• Exploring in vivo consequences of c-Rel overexpression in terminal B cell differentiation

  2016cites this paper
• Interleukin-4-Induced Transcription Association and Synergistic Activation of B: Direct κ Interaction of Stat6 and NF-

  2013cites this paper
• Intracellular mechanisms of cocaine-memory reconsolidation in the basolateral amygdala and dorsal hippocampus

  2013cites this paper
• Molecular Basis of Oncogenesis by NF-κB: From a Bird's Eye View to a RELevant Role in Cancer

  2013cites this paper
• TNFα induced FOXP3-NFκB interaction dampens the tumor suppressor role of FOXP3 in gastric cancer cells.

  2013cites this paper
• of c-Rel and v-Rel by distinct mechanisms. I(kappa)B-alpha regulates cellular localization by I(kappa)B-alpha: evidence that PEST-dependent cytoplasmic retention of v-Rel

  2012cites this paper
• Roles of c-Rel signalling in inflammation and disease.

  2012cites this paper
• The c-Rel Transcription Factor in Development and Disease.

  2011cites this paper
• Molecular Regulation of Inducible Nitric Oxide Synthase

  2010cites this paper
• The DEAD‐box RNA helicase DDX1 interacts with RelA and enhances nuclear factor kappaB‐mediated transcription

  2009cites this paper
• Biphasic Regulation of Il2 Transcription in CD4+ T Cells: Roles for TNF-α Receptor Signaling and Chromatin Structure1

  2008cites this paper
• CAPERα Is a Novel Rel-TAD-Interacting Factor That Inhibits Lymphocyte Transformation by the Potent Rel/NF-κB Oncoprotein v-Rel

  2008cites this paper
• Activation of Nuclear Factor-κB

  2006cites this paper
• Molecular Basis of Oncogenesis by NF-κB

  2006cites this paper
• Regulation of Nuclear NF-_B Action: A Key Role for Posttranslational Modification

  2006cites this paper
• Activation function 1 of glucocorticoid receptor binds TATA-binding protein in vitro and in vivo.

  2006cites this paper
• Cooperative Binding and Synergistic Activation by ReIA and C / EBPIJ on the Intercellular Adhesion Molecule-I Promoter 1

  2005cites this paper
• Shaping the nuclear action of NF-κB

  2004cites this paper
• RNA helicase A interacts with nuclear factor kappaB p65 and functions as a transcriptional coactivator.

  2004cites this paper
• Nuclear factor‐KappaB modulation as a therapeutic approach in hematologic malignancies

  2004cites this paper
• Divergent C-terminal transactivation domains of Rel/NF-κB proteins are critical determinants of their oncogenic potential in lymphocytes

  2004cites this paper
• Shaping the nuclear action of NF-kappaB.

  2004cites this paper
• Transcription factor c-Rel enhances C-reactive protein expression by facilitating the binding of C/EBPbeta to the promoter.

  2003cites this paper
• Dufau among EAR 3 / COUP-TFI , Sp 1 / Sp 3 , and TFIIB Receptor Gene Promoter by Cross Talk Repression of the Luteinizing Hormone

  2003cites this paper
• Repression of the Luteinizing Hormone Receptor Gene Promoter by Cross Talk among EAR3/COUP-TFI, Sp1/Sp3, and TFIIB

  2003cites this paper
• RING Finger Protein AO7 Supports NF-κB-mediated Transcription by Interacting with the Transactivation Domain of the p65 Subunit*

  2003cites this paper
• NF-κB-Dependent Assembly of an Enhanceosome-Like Complex on the Promoter Region of Apoptosis Inhibitor Bfl-1/A1

  2003cites this paper
• Mutations in the v-Rel Transactivation Domain Indicate Altered Phosphorylation and Identify a Subset of NF-κB-Regulated Cell Death Inhibitors Important for v-Rel Transforming Activity

  2003cites this paper
• Activation of second messenger pathways in alveolar macrophages by endotoxin

  2002cites this paper
• Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF‐κB

  2002cites this paper
• Activation of Nuclear Factor-κB

  2001cites this paper
• LPS induction of gene expression in human monocytes.

  2001cites this paper
• Comparison of RANTES chemokine induction by Th1 cytokines in human astroglial cell lines.

  2001cites this paper
• Involvement of the Pro-oncoprotein TLS (Translocated in Liposarcoma) in Nuclear Factor-κB p65-mediated Transcription as a Coactivator*

  2001cites this paper
• Transcriptional Regulation of the E-Selectin Gene

  2001cites this paper
• Regulation of nuclear factor kappa B transactivation. Implication of phosphatidylinositol 3-kinase and protein kinase C zeta in c-Rel activation by tumor necrosis factor alpha.

  2001cites this paper
• Influence of HMG-1 and Adenovirus Oncoprotein E1A on Early Stages of Transcriptional Preinitiation Complex Assembly*

  2000cites this paper
• A constitutive active MEK --> ERK pathway negatively regulates NF-kappa B-dependent gene expression by modulating TATA-binding protein phosphorylation.

  2000cites this paper
• NF-κB and HIV: Linking viral and immune activation

  2000cites this paper
• cRel-TD kinase: a serine/threonine kinase binding in vivo and in vitro c-Rel and phosphorylating its transactivation domain

  2000cites this paper
• Chapter 8 – Molecular Regulation of Inducible Nitric Oxide Synthase

  2000cites this paper
• Tumor Necrosis Factor-α Activation of NF-κB Requires the Phosphorylation of Ser-471 in the Transactivation Domain of c-Rel*

  2000cites this paper
• Octamer Motif is Required for the NF-κB-mediated Induction of the Inducible Nitric Oxide Synthase Gene Expression in RAW 264.7 Macrophages

  1999cites this paper
• The p38 mitogen-activated protein kinase is required for NF-kappaB-dependent gene expression. The role of TATA-binding protein (TBP).

  1999cites this paper
• The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-κB that blocks TNFα-induced apoptosis

  1999cites this paper
• LIM domain-containing protein trip6 can act as a coactivator for the v-Rel transcription factor.

  1999cites this paper
• The Activation Domain of Herpesvirus Saimiri R Protein Interacts with the TATA-Binding Protein

  1999cites this paper
• Multiple mutations contribute to the oncogenicity of the retroviral oncoprotein v-Rel

  1999cites this paper
• The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis.

  1999cites this paper
• Aberrant rel/nfkb genes and activity in human cancer

  1999cites this paper
• The p38 Mitogen-activated Protein Kinase Is Required for NF-κB-dependent Gene Expression

  1999cites this paper
• Activation of Serum Response Factor by RhoA Is Mediated by the Nuclear Factor-κB and C/EBP Transcription Factors*

  1999cites this paper
• Octamer motif is required for the NF-kappaB-mediated induction of the inducible nitric oxide synthase gene expression in RAW 264.7 macrophages.

  1999cites this paper
• Transcriptional repression by the zinc finger protein REST is mediated by titratable nuclear factors

  1999cites this paper
• The partial homeodomain of the transcription factor Pax-5 (BSAP) is an interaction motif for the retinoblastoma and TATA-binding proteins.

  1999cites this paper
• Mapping of a Serine-Rich Domain Essential for the Transcriptional, Antiapoptotic, and Transforming Activities of the v-Rel Oncoprotein

  1999influential citation
• Functional Characterization of Multiple Transactivating Elements in β-Catenin, Some of Which Interact with the TATA-binding Proteinin Vitro *

  1999cites this paper
• The Gcn4p Activation Domain Interacts Specifically In Vitro with RNA Polymerase II Holoenzyme, TFIID, and the Adap-Gcn5p Coactivator Complex

  1998cites this paper
• Interaction of Stat6 and NF-κB: Direct Association and Synergistic Activation of Interleukin-4-Induced Transcription

  1998cites this paper
• Gélinas Cytoplasm and in the Nucleus Regulate c-Rel in the α B κ Distinct Domains of I

  1998cites this paper
• Oncoprotein Transforming Activities of the v-Rel for the Transcriptional , Antiapoptotic , and Mapping of a Serine-Rich Domain Essential

  1998influential citation
• Distinct domains of IkappaBalpha regulate c-Rel in the cytoplasm and in the nucleus.

  1998cites this paper
• Cooperative binding and synergistic activation by RelA and C/EBPbeta on the intercellular adhesion molecule-1 promoter.

  1998cites this paper
• Rel blocks both anti-Fas- and TNFα-induced apoptosis and an intact Rel transactivation domain is essential for this effect

  1998cites this paper
• Distinct Domains of IκBα Regulate c-Rel in the Cytoplasm and in the Nucleus

  1998cites this paper
• Bcl3, an IκB Protein, as a Novel Transcription Coactivator of the Retinoid X Receptor*

  1998cites this paper
• Cross-talk between transcription factors NF-κB and C/EBP in the transcriptional regulation of genes

  1997cites this paper
• and Sp 1 B κ Immunodeficiency Virus Promoter by NF-Transcriptional Activation of the Human Involvement of TFIID and USA Components in

  1997influential citation
• Role of NF-kappaB in the control of apoptotic and proliferative responses in IL-2-responsive T cells.

  1997cites this paper
• Regulation of the tissue factor gene in human monocytic cells. Role of AP-1, NF-kappa B/Rel, and Sp1 proteins in uninduced and lipopolysaccharide-induced expression.

  1997cites this paper
• Divergent transcriptional regulation among expanding human immunodeficiency virus type 1 subtypes

  1997cites this paper
• Rel/NF-kappa B and I kappa B factors in oncogenesis.

  1997cites this paper
• Synergy between Interferon-γ and Tumor Necrosis Factor-α in Transcriptional Activation Is Mediated by Cooperation between Signal Transducer and Activator of Transcription 1 and Nuclear Factor κB*

  1997cites this paper
• A threshold nuclear level of the v-Rel oncoprotein is required for transformation of avian lymphocytes

  1997cites this paper
• Conserved interaction of the papillomavirus E2 transcriptional activator proteins with human and yeast TFIIB proteins

  1997cites this paper
• Role of cyclic AMP response element-binding protein in cyclic AMP inhibition of NF-kappaB-mediated transcription.

  1997cites this paper
• Differences in κB DNA-binding properties of v-Rel and c-Rel are the result of oncogenic mutations in three distinct functional regions of the Rel protein

  1997cites this paper
• v-Rel prevents apoptosis in transformed lymphoid cells and blocks TNFα-induced cell death

  1997cites this paper
• Cross-talk between transcription factors NF-kappa B and C/EBP in the transcriptional regulation of genes.

  1997cites this paper
• CD40 cross-linking induces Ig epsilon germline transcripts in B cells via activation of NF-kappaB: synergy with IL-4 induction.

  1997cites this paper
• A mutant Rel-homology domain promotes transcription by p50/NFkappaB1.

  1997cites this paper
• NF-kappa B-mediated chromatin reconfiguration and transcriptional activation of the HIV-1 enhancer in vitro.

  1996cites this paper
• The reverse two-hybrid system: a genetic scheme for selection against specific protein/protein interactions.

  1996cites this paper
• Identification of seven hydrophobic clusters in GCN4 making redundant contributions to transcriptional activation

  1996cites this paper
• Interferon regulatory factors and TFIIB cooperatively regulate interferon-responsive promoter activity in vivo and in vitro

  1996cites this paper
• Characterization of the interaction between the acidic activation domain of VP16 and the RNA polymerase II initiation factor TFIIB.

  1996cites this paper
• A role for the Msx-1 homeodomain in transcriptional regulation: residues in the N-terminal arm mediate TATA binding protein interaction and transcriptional repression.

  1996cites this paper
• PEST-dependent cytoplasmic retention of v-Rel by I(kappa)B-alpha: evidence that I(kappa)B-alpha regulates cellular localization of c-Rel and v-Rel by distinct mechanisms

  1996cites this paper
• The Retinoblastoma Gene Product (Rb) Induces Binding of a Conformationally Inactive Nuclear Factor-κB*

  1996cites this paper
• Transcriptional regulation of human polyomavirus JC: evidence for a functional interaction between RelA (p65) and the Y-box-binding protein, YB-1

  1996cites this paper
• Synergistic stimulation of avian I kappa B alpha transcription by rel and fos/jun factors.

  1996cites this paper
• Heterogeneous nuclear ribonucleoprotein K is a transcription factor

  1996cites this paper
• The NF-kappaB transcription factor in oncogenesis.

  1996cites this paper
• PEST-Dependent Cytoplasmic Retention of v-Rel by IkB-a: Evidence that IkB-aRegulates Cellular Localization of c-Rel and v-Rel by Distinct Mechanisms

  1996cites this paper
• CCAAT/enhancer binding protein‐alpha amino acid motifs with dual TBP and TFIIB binding ability co‐operate to activate transcription in both yeast and mammalian cells.

  1995cites this paper
• Chromosomes and expression mechanisms

  1995cites this paper
• Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation.

  1995cites this paper
• A mutant v-rel with increased ability to transform B lymphocytes

  1995cites this paper
• Differential Transcriptional Activation in Vitro by NF-B/Rel Proteins (*)

  1995cites this paper
• GAL4 interacts with TATA-binding protein and coactivators

  1995cites this paper