Effects of insulin and antioxidant on plasma 8-hydroxyguanine and tissue 8-hydroxydeoxyguanosine in streptozotocin-induced diabetic rats.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Diabetes

• Publication date

  2001-12-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.2337/DIABETES.50.12.2837PMID 11723068
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Serum 8-hydroxy-guanine levels are increased in diabetic patients.

  2001cited by this paper
• Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

  2000cited by this paper
• What is oxidative stress?

  2000cited by this paper
• Glycoxidation, and protein and DNA oxidation in patients with diabetes mellitus.

  1998cited by this paper
• Review

  1998cited by this paper
• DNA oxidation matters: the HPLC-electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine.

  1998cited by this paper
• Probucol and multivitamins in the prevention of restenosis after coronary angioplasty. Multivitamins and Probucol Study Group.

  1997cited by this paper
• New biomarker evidence of oxidative DNA damage in patients with non‐insulin‐dependent diabetes mellitus

  1997cited by this paper
• [32P]ATP mediates formation of 8-hydroxy-2'-deoxyguanosine from 2'-deoxyguanosine, a possible problem in the 32P-postlabeling assay.

  1997cited by this paper
• Oxidative Stress and Diabetic Vascular Complications

  1996cited by this paper
• Oxidative damage to DNA in diabetes mellitus.

  1996cited by this paper
• Assays of oxidative DNA damage biomarkers 8-oxo-2'-deoxyguanosine and 8-oxoguanine in nuclear DNA and biological fluids by high-performance liquid chromatography with electrochemical detection.

  1994influential reference
• DNA damage in the kidneys of diabetic rats exhibiting microalbuminuria.

  1994cited by this paper
• Vitamin E consumption and the risk of coronary heart disease in men.

  1993cited by this paper
• Vitamin E consumption and the risk of coronary disease in women.

  1993cited by this paper
• Oxidative DNA damage estimated by 8-hydroxydeoxyguanosine excretion in humans: influence of smoking, gender and body mass index.

  1992cited by this paper
• Assay of excised oxidative DNA lesions: isolation of 8-oxoguanine and its nucleoside derivatives from biological fluids with a monoclonal antibody column.

  1992cited by this paper
• An endonuclease activity in human polymorphonuclear neutrophils that removes 8-hydroxyguanine residues from DNA+.

  1991cited by this paper
• 8-oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity.

  1991cited by this paper
• Protein glycation and oxidative stress in diabetes mellitus and ageing.

  1991cited by this paper
• Role of Oxidative Stress in Development of Complications in Diabetes

  1991cited by this paper
• [54] In vivo oxidative DNA damage : measurement of 8-hydroxy-2'-deoxyguanosine in DNA and urine by high-performance liquid chromatography with electrochemical detection

  1990cited by this paper
• In vivo oxidative DNA damage: measurement of 8-hydroxy-2'-deoxyguanosine in DNA and urine by high-performance liquid chromatography with electrochemical detection.

  1990cited by this paper
• Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine.

  1990cited by this paper
• Endogenous oxidative DNA damage, aging, and cancer.

  1989cited by this paper
• Lipid peroxides and atherosclerosis.

  1989cited by this paper
• Urinary 8-hydroxy-2'-deoxyguanosine as a biological marker of in vivo oxidative DNA damage.

  1989cited by this paper
• Free radicals and diabetes.

  1988cited by this paper
• Normal oxidative damage to mitochondrial and nuclear DNA is extensive.

  1988cited by this paper
• Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair.

  1986cited by this paper

• Mechanisms in diabetes mellitus: Relationships to metabolism and/or neoplasia.

  2026cites this paper
• Reappraisal of cardiometabolic stress in type 2 diabetes mellitus patients receiving glimepiride versus insulin under bitherapy

  2025cites this paper
• Hepatoprotective Effects of Curcumin on Liver Injury in Streptozocin-induced Diabetic Rats

  2024cites this paper
• Diabetic Neuropathy: An Overview of Molecular Pathways and Protective Mechanisms of Phytobioactives.

  2023cites this paper
• Recent progress in the development of fluorescent probes for imaging pathological oxidative stress.

  2023cites this paper
• In Vivo Evaluation of Nanoemulsion Formulations for Metformin and Repaglinide Alone and Combination.

  2023cites this paper
• Cardioprotective Effect of Pistacia vera L. (Green Pistachio) Hull Extract in Wistar Albino Rats with Doxorubicin-Induced Cardiac Damage

  2023cites this paper
• Mechanistic Insight into Oxidative Stress-Triggered Signaling Pathways and Type 2 Diabetes

  2022cites this paper
• Erythrina subumbrans leaves extracts improved Diabetic condition by reducing MDA and 8-OHDG on Rat model

  2022cites this paper
• Eurasian Journal of Veterinary Sciences

  2022cites this paper
• Aerobic exercise training alleviates renal injury in db/db mice through inhibiting Nox4-mediated NLRP3 inflammasome activation.

  2022cites this paper
• Antioxidant Activity, Metal Chelating Ability and DNA Protective Effect of the Hydroethanolic Extracts of Crocus sativus Stigmas, Tepals and Leaves

  2022cites this paper
• Potential Protective Effects of Strawberry (Fragaria Ananassa) Leaves Against Alloxan Induced Type 2 Diabetes in Rats: Molecular, Biological and Biochemical Studies

  2022cites this paper
• Effect of oligosaccharides on the antioxidant, lipid and inflammatory profiles of rats with streptozotocin-induced diabetes mellitus

  2022cites this paper
• Roles of mTOR in Diabetic Kidney Disease

  2021cites this paper
• Investigation of the Effects of L-carnitine and magnesium on Oxidative Stress and Cytokines in the Tissue of Experimental diabetic rats

  2021cites this paper
• Association of 8-hydroxy-2’-deoxyguanosine with various demographic and biochemical parameter in a group of hemodialysis patients

  2020cites this paper
• Effects of Moringa oleifera on oxidative stress, apoptotic and inflammatory biomarkers in streptozotocin-induced diabetic animal model

  2020cites this paper
• 8-Oxo-7,8-Dihydro-2′-Deoxyguanosine (8-oxodG) and 8-Hydroxy-2′-Deoxyguanosine (8-OHdG) as a Potential Biomarker for Gestational Diabetes Mellitus (GDM) Development

  2020cites this paper
• Effect of dapagliflozin alone and in combination with insulin in a rat model of type 1 diabetes

  2020cites this paper
• Effects of Hydroalcoholic Leaf Extract of Avicennia marina on Apoptotic, Inflammatory, Oxidative Stress, and Lipid Peroxidation Indices and Liver Histology of Type 1 Diabetic Rats

  2020cites this paper
• Kecombrang (Etlingera elatior) Leaves Ethanol Extract Effect to Lens and Erythrocyte Aldose Reductase Activity in Wistar strain white rats (Rattus norvegicus) Streptozotocin induced

  2019cites this paper
• Molecular mechanism of diabetic neuropathy and its pharmacotherapeutic targets

  2018cites this paper
• The Effect of Lycopene Treatment on Oxidative DNA Damage of Experimental Diabetic Rats

  2018cites this paper
• Medicinal Plants with Multiple Effects on Diabetes Mellitus and Its Complications: a Systematic Review

  2018cites this paper
• Investigation of role magnetized water used in supplementary feeding for honeybees to modulate the genotoxic side effects induced by cyclophosphamide in mice bone marrow cells

  2017cites this paper
• Potential application of the oxidative nucleic acid damage biomarkers in detection of diseases

  2017cites this paper
• Furan induced ovarian damage in non-diabetic and diabetic rats and cellular protective role of lycopene

  2017cites this paper
• The effects of caffeic acid phenethyl ester on streptozotocin-induced diabetic liver injury.

  2016cites this paper
• The research and development on the antioxidants in prevention of diabetic complications.

  2016cites this paper
• Evidence of Anti-hyperglycemic and Anti-oxidant Effect of Passiflora edulis flavicarpa (Sims.) in Streptozotocin Induced Diabetic Rats

  2015influential citation
• EFFECTS OF PALM DATES (PHOENIX DACTYLIFERA L) EXTRACTS ON HEPATIC DYSFUNCTIONS IN TYPE 2 DIABETIC RAT MODEL

  2015cites this paper
• Analysis of the oxidative damage of DNA, RNA, and their metabolites induced by hyperglycemia and related nephropathy in Sprague Dawley rats

  2015cites this paper
• Liken Ekstrelerinin Sağlıklı Ratlar Üzerindeki Etkileri ve Bu Ekstrelerin Diyabete Bağlı Çoklu Organ Yetmezliğinin Önlenmesinde Medikal Kullanımı

  2015cites this paper
• Effects of kolaviron on hepatic oxidative stress in streptozotocin induced diabetes

  2015cites this paper
• Effects of Metalloporphyrins on Reducing Inflammation and Autoimmunity

  2014cites this paper
• Tissue specific oxidative stress profile in relation to glycaemic regulation in mice

  2014cites this paper
• Role of Dietary and Endogenous Antioxidants in Diabetes

  2014cites this paper
• The relationship among serum levels of manganese superoxide dismutase and mtDNA 8-hydroxy-2'-deoxyguanosine, and dietary antioxidants intake in Type 2 Diabetes

  2014cites this paper
• Oxidative Stress and Diabetic Complications: The Role of Antioxidant Vitamins and Flavonoids

  2014cites this paper
• The Effects of Lichens Extracts in The Healthy Rats and The Medical Utility of These Extracts in The Prevention of Diabetes-Associated Multiple Organ Failures

  2014cites this paper
• Effects of metformin plus gliclazide versus metformin plus glimepiride on cardiovascular risk factors in patients with type 2 diabetes mellitus.

  2014cites this paper
• Hepatoprotective effects of melatonin against pronecrotic cellular events in streptozotocin-induced diabetic rats

  2014cites this paper
• IMPACT OF OXIDATIVE STRESS IN DEVELOPMENT OF DIABETIC RETINOPATHY AND ANTIOXIDANTS AS TREATMENT OPTION

  2014cites this paper
• The Effect of Lithospermic Acid, an Antioxidant, on Development of Diabetic Retinopathy in Spontaneously Obese Diabetic Rats

  2014cites this paper
• Kolaviron, a biflavonoid complex of Garcinia kola seeds modulates apoptosis by suppressing oxidative stress and inflammation in diabetes-induced nephrotoxic rats.

  2014cites this paper
• Diabetes, an inflammatory process: Oxidative Stress and TNF-alpha involved in hepatic complication

  2013cites this paper
• Role of Liver in Glucose Metabolism

  2013cites this paper
• The role of antioxidants and other agents in alleviating hyperglycemia mediated oxidative stress and injury in liver.

  2013cites this paper
• Antioxidant, anti-diabetic and renal protective properties of Stevia rebaudiana.

  2013cites this paper
• The effects of dietary supplementation of tomato peel ultrafine powder on glycemic response in streptozotocin-induced diabetic rats and blood lipids in high-fat diet rats

  2013influential citation
• 8-hydroxyguanine in urine and serum as an oxidative stress marker: effects of diabetes and aging.

  2013cites this paper
• Xanthomonas campestris pv. campestris race 1 is the main causal agent of black rot of Brassicas in Southern Mozambique

  2013cites this paper
• Effect of the magnetized water supplementation on blood glucose, lymphocyte DNA damage, antioxidant status, and lipid profiles in STZ-induced rats

  2013cites this paper
• Ameliorative effects of resveratrol on liver injury in streptozotocin‐induced diabetic rats

  2012cites this paper
• Relationship between NADPH oxidase p22phox C242T, PARP-1 Val762Ala polymorphisms, angiographically verified coronary artery disease and myocardial infarction in South Indian patients with type 2 diabetes mellitus.

  2012cites this paper
• Redox-regulating role of insulin: the essence of insulin effect.

  2012cites this paper
• 8-Hydroxydeoxyguanosine: not mere biomarker for oxidative stress, but remedy for oxidative stress-implicated gastrointestinal diseases.

  2012cites this paper
• Glycemic and oxidative status of patients with type 2 diabetes mellitus following oral administration of alpha-lipoic acid: a randomized double-blinded placebo-controlled study.

  2012cites this paper
• Determinants of myocardial and vascular function in young subjects with Type 1 diabetes mellitus

  2012cites this paper
• Alkaline, Endo III and FPG modified comet assay as biomarkers for the detection of oxidative DNA damage in rats with experimentally induced diabetes.

  2011cites this paper
• Cytochrome P450 2E1 and hyperglycemia-induced liver injury

  2011cites this paper
• Urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine as a biomarker in type 2 diabetes.

  2011cites this paper
• Aldose Reductase Inhibitor Fidarestat Prevents Diabetic Ocular Complications in Spontaneously Diabetic Torii Rats

  2011cites this paper
• Rôle du stress oxydant en période néonatale dans l'hypertension artérielle et la dysfonction vasculaire et métabolique de l'adulte

  2011cites this paper
• Oxidative and Anti-oxidative Status in Blood of Streptozotocin-induced Diabetic Piglets

  2011cites this paper
• Antioxidant and Radical Scavenging Properties of Garlic Oil in Streptozotocin Induced Diabetic Rats

  2011cites this paper
• The role of vitamin E and oxidative stress in diabetes complications.

  2010cites this paper
• Hyperglycemia induces apoptosis in rat liver through the increase of hydroxyl radical: new insights into the insulin effect.

  2010cites this paper
• ANTIDIABETIC, ANTIATHEROSCLEROTIC AND HEPATOPROTECTIVE PROPERTIES OF DECALEPIS HAMILTONII IN STREPTOZOTOCIN‐INDUCED DIABETIC RATS

  2010cites this paper
• Role of nitric oxide, superoxide, peroxynitrite and PARP in diabetic retinopathy.

  2009cites this paper
• Reversal of the Mitochondrial Phenotype and Slow Development of Oxidative Biomarkers of Aging in Long-lived Mclk1+/− Mice*

  2009cites this paper
• Lipid peroxidation in early type 1 diabetes mellitus is unassociated with oxidative damage to DNA.

  2009cites this paper
• Influence of pyridoxylidene aminoguanidine on biomarkers of the oxidative stress and selected metabolic parameters of rats with diabetes mellitus.

  2009cites this paper
• Hypothesis for the Formation and Maintenance of Chronic Wounds

  2009cites this paper
• Aerobic Performance and Antioxidant Protection in Runners

  2009cites this paper
• Immunolocalization of 8-OHdG and OGG1 in pancreatic islets of streptozotocin-induced diabetic rats.

  2009cites this paper
• Hyperglycemia induced changes in liver: in vivo and in vitro studies.

  2009cites this paper
• 8-OHdG sensing with MIP based solid phase extraction and QCM technique

  2009cites this paper
• Intermittent High Glucose Stimulate MCP-l, IL-18, and PAI-1, but Inhibit Adiponectin Expression and Secretion in Adipocytes Dependent of ROS

  2009cites this paper
• Effect of the antioxidant α-lipoic acid on apoptosis in human umbilical vein endothelial cells induced by high glucose

  2008cites this paper
• Pharmacological Intervention by Exogenous Superoxide Dismutase Attenuates Diabetes-Induced Oxidative and Nitrosative Stress Mediated Renal Damage

  2008cites this paper
• PPARGC1A Variation Associated With DNA Damage, Diabetes, and Cardiovascular Diseases

  2008cites this paper
• The Effect of Muscle-Damaging Exercise on Blood and Skeletal Muscle Oxidative Stress

  2008cites this paper
• Glutathione Peroxidase 3 Mediates the Antioxidant Effect of Peroxisome Proliferator-Activated Receptor γ in Human Skeletal Muscle Cells

  2008cites this paper
• Primary role of superoxide anion generation in the cascade of events leading to endothelial dysfunction and damage in high glucose treated HUVEC.

  2007cites this paper
• Free Radicals, Antioxidants and Diabetes: Embryopathy, Retinopathy, Neuropathy, Nephropathy and Cardiovascular Complications

  2007cites this paper
• Probucol and atorvastatin decrease urinary 8-hydroxy-2'-deoxyguanosine in patients with diabetes and hypercholesterolemia.

  2006cites this paper
• DNA oxidation and superoxide dismutase in the kidney of diabetic animals: effects of pioglitazone and repaglinide

  2006cites this paper
• Mechanism of Developing Diabetic Vascular Complication by Oxidative Stress

  2006cites this paper
• Effect of curcumin on proliferation of human retinal endothelial cells under in vitro conditions.

  2006cites this paper
• Induction of 8-Hydroxydeoxyguanosine Formation in DNA by Fructose and Glucose in the Presence of Copper

  2006cites this paper
• INHIBITORY ACTIVITY OF FLAVONOIDS ON THE LENS ALDOSE REDUCTASE OF HEALTHY AND DIABETIC RATS

  2006cites this paper
• Valores de 8-hidroxi-2'-desoxiguanosina y de peroxidación lipídica en pacientes con insuficiencia cardiaca

  2006cites this paper
• Valores de 8-hidroxi-2-desoxiguanosina y de peroxidación lipídica en pacientes con insuficiencia cardiaca

  2006cites this paper
• [8-hydroxy-2'-deoxyguanosine and lipid peroxidation in patients with heart failure].

  2006cites this paper
• What influences the level of oxidative stress as measured by 8-hydroxy-2'-deoxyguanosine in patients on hemodialysis?

  2006cites this paper
• Enhanced hypothalamic AMP-activated protein kinase activity contributes to hyperphagia in diabetic rats.

  2005cites this paper
• Role of Poly(ADP-Ribose) Polymerase-1 Activation in the Pathogenesis of Diabetic Complications: Endothelial Dysfunction, as a Common Underlying Theme

  2005cites this paper
• Poly(ADP-Ribose) Polymerase Activation and Nitrosative Stress in the Development of Cardiovascular Disease in Diabetes

  2005cites this paper