The role of cytokines in the development of normal-tissue reactions after radiotherapy.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Strahlentherapie und Onkologie (Print)

• Publication date

  1998-11-01

• Fields of study

  Medicine, Environmental Science

• Identifiers
  PMID 9830449
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• IL-6 cytokine family and signal transduction: a model of the cytokine system

  2004cited by this paper
• Keratinocyte growth factor protects mice from chemotherapy and radiation-induced gastrointestinal injury and mortality.

  1998cited by this paper
• Differentiation state of skin fibroblast cultures versus risk of subcutaneous fibrosis after radiotherapy.

  1998cited by this paper
• Latent transforming growth factor β1 activation in situ: quantitative and functional evidence after low‐dose γ‐irradiation 1

  1997cited by this paper
• Increased transforming growth factor beta (TGF-beta) immunoreactivity is independently associated with chronic injury in both consequential and primary radiation enteropathy.

  1997cited by this paper
• Induction of interleukin 6 by ionizing radiation in a human epithelial cell line: control by corticosteroids.

  1997cited by this paper
• Latent transforming growth factor-beta: structural features and mechanisms of activation.

  1997cited by this paper
• Changes in plasma transforming growth factor beta during radiotherapy and the risk of symptomatic radiation-induced pneumonitis.

  1997cited by this paper
• Association of transforming growth factor beta (TGF-beta) immunoreactivity with specific histopathologic lesions in subacute and chronic experimental radiation enteropathy.

  1996cited by this paper
• Early and persistent alterations in the expression of interleukin-1 alpha, interleukin-1 beta and tumor necrosis factor alpha mRNA levels in fibrosis-resistant and sensitive mice after thoracic irradiation.

  1996cited by this paper
• Radiotherapy-related lung fibrosis enhanced by tamoxifen.

  1996cited by this paper
• Long-term expression of transforming growth factor TGF beta 1 in mouse skin after localized beta-irradiation.

  1996cited by this paper
• Radiation-induced alteration of rat mesangial cell transforming growth factor-beta and expression of the genes associated with the extracellular matrix.

  1996cited by this paper
• Differences in correlation of mRNA gene expression in mice sensitive and resistant to radiation-induced pulmonary fibrosis.

  1995cited by this paper
• Release and activation of platelet latent TGF–β in blood clots during dissolution with plasmin

  1995cited by this paper
• A perpetual cascade of cytokines postirradiation leads to pulmonary fibrosis.

  1995cited by this paper
• Cellular basis of radiation-induced fibrosis.

  1995cited by this paper
• Fibrogenic cytokines and connective tissue production

  1994cited by this paper
• Expression of fibrogenic cytokines in rat small intestine after fractionated irradiation.

  1994cited by this paper
• Transforming growth factor-beta activation in irradiated murine mammary gland.

  1994cited by this paper
• Cytokine regulation of metalloproteinase gene expression

  1993cited by this paper
• Temporal modulation of TGF-beta 1 and beta-actin gene expression in pig skin and muscular fibrosis after ionizing radiation.

  1993cited by this paper
• Release of interleukin-1 by human alveolar macrophages after in vitro irradiation.

  1993cited by this paper
• Radiation-induced transforming growth factor beta and subsequent extracellular matrix reorganization in murine mammary gland.

  1993cited by this paper
• Molecular biology mechanisms in the radiation induction of pulmonary injury syndromes: interrelationship between the alveolar macrophage and the septal fibroblast.

  1992cited by this paper
• Cytokine release from mononuclear cells in patients irradiated for breast cancer.

  1991cited by this paper
• Tumor necrosis factor gene expression is mediated by protein kinase C following activation by ionizing radiation.

  1991cited by this paper
• Interleukin-1 and interleukin-1 antagonism.

  1991cited by this paper
• Modulation of gene expression in Syrian hamster embryo cells following ionizing radiation.

  1990cited by this paper
• TGF-beta induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop.

  1990cited by this paper
• Transforming growth factor beta: a promotor of late connective tissue injury following radiotherapy?

  1990cited by this paper
• Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation.

  1989cited by this paper
• Interleukin-1 mitogenic activity for fibroblasts and smooth muscle cells is due to PDGF-AA.

  1989cited by this paper
• Tumor necrosis factor-induced expression of platelet-derived growth factor A-chain messenger RNA in fibroblasts.

  1989cited by this paper
• Transforming growth factor beta (TGF beta) causes a persistent increase in steady-state amounts of type I and type III collagen and fibronectin mRNAs in normal human dermal fibroblasts.

  1987cited by this paper
• Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor.

  1987cited by this paper

• Curcumin as a modulator of IL-18: A promising therapeutic approach for inflammatory diseases

  2026cites this paper
• Pain-relieving Effects of Autologous Fat Grafting in Breast Cancer Surgery: A Scoping Review

  2024cites this paper
• Outcomes of Dermal Regeneration Templates in Irradiated and Nonirradiated Scalp Defects

  2024cites this paper
• Determining the optimal radiation‐surgery interval (RSI) for oncologic proctectomy following radiotherapy for rectal adenocarcinoma

  2023cites this paper
• Radiation-induced skin and heart toxicity in patients with breast cancer treated with adjuvant proton radiotherapy: a comparison with photon radiotherapy.

  2023cites this paper
• Management of Radiation-induced Tissue Injuries: A Review of Current Treatment Strategies

  2023cites this paper
• Urinary Bladder Matrix Improves Irradiated Wound Healing in a Murine Model

  2022cites this paper
• P144 a Transforming Growth Factor Beta Inhibitor Peptide, Generates Antifibrogenic Effects in a Radiotherapy Induced Fibrosis Model

  2022cites this paper
• Improved prediction of radiation pneumonitis by combining biological and radiobiological parameters using a data-driven Bayesian network analysis

  2022cites this paper
• Gamma-Linolenic Acid (GLA) Protects against Ionizing Radiation-Induced Damage: An In Vitro and In Vivo Study

  2022cites this paper
• Effects of radiation on endothelial barrier and vascular integrity

  2021cites this paper
• Various acute cutaneous manifestations in Head and Neck cancer patients treated with radiation therapy

  2020cites this paper
• Pediatric Radiotherapy: Surgical Considerations, Sequelae, and Future Directions

  2020cites this paper
• Neoadjuvant Radiotherapy-Related Wound Morbidity in Soft Tissue Sarcoma: Perspectives for Radioprotective Agents

  2020cites this paper
• Lymphocyte count changes in cancer patients under radiation therapy-A prospective study

  2020cites this paper
• Biological mesh used to repair perineal hernias following abdominoperineal resection for anorectal cancer.

  2020cites this paper
• Within-person changes in cancer-related distress predict breast cancer survivors' inflammation across treatment.

  2020cites this paper
• High-intensity interval training can modulate the systemic inflammation and HSP70 in the breast cancer: a randomized control trial

  2019cites this paper
• Transcutaneous oxegen measurement in the area of soft tissue radiation-induced fibrosis in patients with breast cancer

  2018cites this paper
• Effect of fresh human amniotic membrane on radiation-induced wounds in a murine experimental model

  2018cites this paper
• The Role of the Mammalian Target of Rapamycin (mTOR) in Pulmonary Fibrosis

  2018cites this paper
• Soluble interleukin-6 receptor mediated fatigue highlights immunological heterogeneity of patients with early breast cancer who undergo radiation therapy

  2018cites this paper
• Topical Fibronectin Improves Wound Healing of Irradiated Skin

  2017cites this paper
• Biology of high single doses of IORT: RBE, 5 R’s, and other biological aspects

  2017cites this paper
• Mindfulness Meditation for Fibromyalgia: Mechanistic and Clinical Considerations

  2017cites this paper
• Impaired wound healing after radiation therapy: A systematic review of pathogenesis and treatment

  2017cites this paper
• YORGUNLUK YAŞAYAN KANSERLİ BİREYLERDE BÜTÜNLEŞİK SAĞLIK UYGULAMASI: AKUPRES

  2017cites this paper
• Effect of Radiotherapy on the Oral Cavity

  2017cites this paper
• Radiogenomics: A systems biology approach to understanding genetic risk factors for radiotherapy toxicity?

  2016cites this paper
• Is there a place for a biological mesh in perineal hernia repair?

  2016cites this paper
• [Reconstruction of Defects after Oncologic Resection and Radiation - Indications for Microsurgical Reconstruction].

  2015cites this paper
• Effect of radiation on hepatic fat metabolism in rat and mouse: A role of radiation-induced TNF-α in the regulation of FAT/CD36

  2015cites this paper
• The Impact of Chemotherapy and Radiation Therapy on the Remodeling of Acellular Dermal Matrices in Staged, Prosthetic Breast Reconstruction

  2015cites this paper
• Acute adaptive immune response correlates with late radiation-induced pulmonary fibrosis in mice

  2015cites this paper
• Potenzial adipogener Stammzellen bei radiogenen Wundheilungsstörungen

  2015cites this paper
• 3‐aminobenzamide, a poly (ADP ribose) polymerase inhibitor, enhances wound healing in whole body gamma irradiated model

  2015cites this paper
• Triptolide Mitigates Radiation-Induced Pulmonary Fibrosis

  2015influential citation
• Defektrekonstruktion nach onkologischer Resektion und Bestrahlung – Indikationen zur mikrochirurgischen Rekonstruktion

  2015cites this paper
• [Potential of adipose-derived stem cells concerning the treatment of wound healing complications after radiotherapy].

  2015cites this paper
• Investigation into the role of the cholinergic system in radiation-induced damage in the rat liver and ileum

  2014cites this paper
• Radiotherapy Induced Achalasia-like Esophageal Motor Disorder

  2014cites this paper
• Mesenchymal stem cells are sensitive to treatment with kinase inhibitors and ionizing radiation

  2014cites this paper
• Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology.

  2014cites this paper
• Stomach, Small and Large Intestines

  2014cites this paper
• Molecular Mechanisms of Radiation Induced Injury

  2014cites this paper
• Inhibition of radiation-induced skin fibrosis with imatinib

  2013cites this paper
• Wound healing after radiation therapy: Review of the literature

  2012cites this paper
• Molecular Pathways: Emerging Pathways Mediating Growth, Invasion, and Metastasis of Tumors Progressing in an Irradiated Microenvironment

  2012influential citation
• Post-cancer fatigue is not associated with immune activation or altered cytokine production.

  2012cites this paper
• Consequences of Radiotherapy for Breast Reconstruction

  2012cites this paper
• Radiation fibrosis of the vocal fold: From man to mouse

  2012cites this paper
• Impact of radiotherapy on clinical outcome in reconstructive surgery

  2012cites this paper
• Randomised clinical trial: preventive treatment with topical rectal beclomethasone dipropionate reduces post‐radiation risk of bleeding in patients irradiated for prostate cancer

  2011cites this paper
• Muscle endurance, cancer‐related fatigue, and radiotherapy in prostate cancer survivors

  2011cites this paper
• “Pelvic radiation disease”: New understanding and new solutions for a new disease in the era of cancer survivorship

  2011cites this paper
• Strahlendermatitis

  2010cites this paper
• Exercise, sleep quality, and mediators of sleep in breast and prostate cancer patients receiving radiation therapy.

  2010cites this paper
• Fatigue during radiotherapy for early-stage breast cancer and its relationship to irradiated volumes, IL-6sR and anxiety and depression : towards a prognostic model

  2010cites this paper
• Effect of tumour necrosis factor‐α and irradiation alone or in combination on the viability of hepatocellular and biliary adenocarcinoma cell lines in vitro

  2009cites this paper
• Comparison of Expression Profiles of Several Fibroblast Growth Factor Receptors in the Mouse Jejunum: Suggestive Evidence for a Differential Radioprotective Effect among Major FGF Family Members and the Potency of FGF1

  2009cites this paper
• Positive affect and radiation-induced inflammation: insights into inflammatory regulation?

  2009cites this paper
• Biological Effect of Single, Very Large Dose Fractions as Used in Intraoperative Radiotherapy (IORT)

  2009cites this paper
• Lovastatin attenuates ionizing radiation-induced normal tissue damage in vivo.

  2009cites this paper
• Free flap transfer in cranio-maxillofacial surgery: a review of the current data

  2008cites this paper
• Pathophysiologie der chronischen Wunde

  2008cites this paper
• TGF-beta antisense oligonucleotides modulate expression of matrix metalloproteinases in isolated fibroblasts from radiated skin.

  2008cites this paper
• Approaches to the prevention and management of radiation colitis

  2008cites this paper
• Abrogation of TGF-beta by antisense oligonucleotides modulates expression of VEGF and increases angiogenic potential in isolated fibroblasts from radiated skin.

  2008cites this paper
• Inhibition of the Tumor Necrosis Factor-α Pathway Is Radioprotective for the Lung

  2008cites this paper
• Chitosan application to X-ray irradiated wound in dogs.

  2007cites this paper
• Cancer-related fatigue: links with inflammation in cancer patients and survivors.

  2007cites this paper
• Quality of Life following Chemoradiation and Postoperative Radiation for Locally Advanced Head and Neck Cancer

  2007cites this paper
• x-Irradiation in rat liver: consequent upregulation of hepcidin and downregulation of hemojuvelin and ferroportin-1 gene expression.

  2007cites this paper
• Molecular mechanisms of late normal tissue injury.

  2007cites this paper
• Using biological markers to predict risk of radiation injury.

  2007cites this paper
• Impact of swallowing therapy on aspiration rate following treatment for locally advanced head and neck cancer.

  2007cites this paper
• Increase of hepcidin plasma and urine levels is associated with acute proctitis and changes in hemoglobin levels in primary radiotherapy for prostate cancer

  2007cites this paper
• Cancer related fatigue: A focus on breast cancer and Hodgkin's disease survivors

  2007cites this paper
• Ionizing radiation induces degranulation of human mast cells and release of tryptase

  2007cites this paper
• TGFbeta-1 dependent fast stimulation of ATM and p53 phosphorylation following exposure to ionizing radiation does not involve TGFbeta-receptor I signalling.

  2007cites this paper
• Zur Interaktion von Strahlentherapie und Tamoxifen beim Mammakarzinom

  2007cites this paper
• Radiation dermatitis: implicated factors, clinical aspects, possible prevention, and medical care.

  2007cites this paper
• Osteoradionecrosis of the mandible: Etiology, prevention, diagnosis and treatment

  2007cites this paper
• [On the interaction of adjuvant radiotherapy and tamoxifen treatment for breast cancer].

  2007cites this paper
• Die prognostische Bedeutung des TGF-beta1 Plasmaspiegels für die radiogene Pneumonitis und das Tumoransprechen bei der Radiotherapie des Bronchialkarzinoms

  2007cites this paper
• TGFβ-1 dependent fast stimulation of ATM and p53 phosphorylation following exposure to ionizing radiation does not involve TGFβ-receptor I signalling

  2007cites this paper
• x-Irradiation in Rat Liver: ConsequentUpregulationofHepcidin andDownregulationofHemojuvelin

  2007cites this paper
• The treatment of osteoradionecrosis of the mandible: the case for hyperbaric oxygen and bone graft reconstruction.

  2006cites this paper
• The association between fatigue and in X ammatory marker levels in cancer patients : A quantitative review

  2006cites this paper
• Inflammatory Biomarkers for Persistent Fatigue in Breast Cancer Survivors

  2006cites this paper
• Management of skin and related reactions to radiotherapy.

  2006cites this paper
• Curcumin protects against radiation-induced acute and chronic cutaneous toxicity in mice and decreases mRNA expression of inflammatory and fibrogenic cytokines.

  2006cites this paper
• Selective Radioprotection of Normal Tissues by Bowman-Birk Proteinase Inhibitor (BBI) in Mice

  2005cites this paper
• Radiation Induced Lung Reactions in Breast Cancer Therapy

  2005cites this paper
• Der Einfluss ionisierender Strahlen auf die Entwicklung der Sekundärkatarakt in vitro

  2005cites this paper
• Experimental study of mineralization in mandibular bone distraction with irradiation during the consolidation phase.

  2005cites this paper
• Radiotherapy and wound healing

  2005cites this paper
• Influence of locoregional radiation treatment on tumor necrosis factor-alpha and interleukin-6 in the serum of patients with head and neck cancer.

  2005cites this paper
• [The influence of ionizing radiation on the development of posterior capsule opacification in vitro].

  2005cites this paper
• Oral complications of radiotherapy in head and neck cancer

  2004cites this paper