Resistance of HIV‐1 to antiretroviral agents in blood and seminal plasma: implications for transmission

No abstract is available for this paper.

• Publication year

  1998

• Venue

  AIDS (London)

• Publication date

  1998-10-22

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1097/00002030-199815000-00003PMID 9814860
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Evolutionary trees from DNA sequences: A maximum likelihood approach

  2005cited by this paper
• Simultaneous vs sequential initiation of therapy with indinavir, zidovudine, and lamivudine for HIV-1 infection: 100-week follow-up.

  1998cited by this paper
• Human Immunodeficiency Virus Type 1 Populations in Blood and Semen

  1998cited by this paper
• Comparative Performance of High-Density Oligonucleotide Sequencing and Dideoxynucleotide Sequencing of HIV Type 1 pol from Clinical Samples

  1998cited by this paper
• Heterosexual HIV-1 transmission and viral load in hemophilic patients.

  1998cited by this paper
• Association between culturable human immunodeficiency virus type 1 (HIV-1) in semen and HIV-1 RNA levels in semen and blood: evidence for compartmentalization of HIV-1 between semen and blood.

  1998cited by this paper
• Sexual transmission of an HIV-1 variant resistant to multiple reverse-transcriptase and protease inhibitors.

  1998cited by this paper
• Reduction of concentration of HIV-1 in semen after treatment of urethritis: implications for prevention of sexual transmission of HIV-1. AIDSCAP Malawi Research Group.

  1997cited by this paper
• High viral load in semen of human immunodeficiency virus type 1-infected men at all stages of disease and its reduction by therapy with protease and nonnucleoside reverse transcriptase inhibitors

  1997cited by this paper
• Effects of reverse transcriptase inhibitor therapy on the HIV-1 viral burden in semen.

  1997cited by this paper
• Effect of antiviral treatment on the shedding of HIV‐1 in semen

  1997cited by this paper
• Transmission of human immunodeficiency virus type 1 resistant to nevirapine and zidovudine. Sydney Primary HIV Infection Study Group.

  1997cited by this paper
• HIV-1 in semen: an isolated virus reservoir.

  1997cited by this paper
• Quantification of HIV in semen: correlation with antiviral treatment and immune status

  1997cited by this paper
• Sexual transmission of HIV.

  1997cited by this paper
• A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team.

  1997cited by this paper
• Maintaining the integrity of human immunodeficiency virus sequence databases

  1996cited by this paper
• Host-parasite dynamics and outgrowth of virus containing a single K70R amino acid change in reverse transcriptase are responsible for the loss of human immunodeficiency virus type 1 RNA load suppression by zidovudine.

  1996cited by this paper
• Significance of amino acid variation at human immunodeficiency virus type 1 reverse transcriptase residue 210 for zidovudine susceptibility

  1996cited by this paper
• Genetic characterization of human immunodeficiency virus type 1 in blood and genital secretions: evidence for viral compartmentalization and selection during sexual transmission

  1996cited by this paper
• Antiviral and resistance studies of AG1343, an orally bioavailable inhibitor of human immunodeficiency virus protease

  1996cited by this paper
• Correlation of HIV-1 RNA levels in plasma and heterosexual transmission of HIV-1 from infected transfusion recipients.

  1996cited by this paper
• In vivo sequence diversity of the protease of human immunodeficiency virus type 1: presence of protease inhibitor-resistant variants in untreated subjects

  1996cited by this paper
• Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor

  1996cited by this paper
• Ordered accumulation of mutations in HIV protease confers resistance to ritonavir

  1996cited by this paper
• Extensive polymorphisms observed in HIV–1 clade B protease gene using high–density oligonucleotide arrays

  1996cited by this paper
• Quantitation of human immunodeficiency virus type 1 RNA in cell free seminal plasma: comparison of NASBA with Amplicor reverse transcription-PCR amplification and correlation with quantitative culture.

  1996cited by this paper
• The Effect of High-Dose Saquinavir on Viral Load and CD4+ T-Cell Counts in HIV-Infected Patients

  1996cited by this paper
• Maternal viral load, zidovudine treatment, and the risk of transmission of human immunodeficiency virus type 1 from mother to infant. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group.

  1996cited by this paper
• An in vivo mutation from leucine to tryptophan at position 210 in human immunodeficiency virus type 1 reverse transcriptase contributes to high-level resistance to 3'-azido-3'-deoxythymidine

  1996cited by this paper
• Factors influencing human immunodeficiency virus type 1 transmission by blood transfusion. Transfusion Safety Study Group.

  1996cited by this paper
• In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors

  1995cited by this paper
• Maternal plasma human immunodeficiency virus type 1 RNA level: a determinant and projected threshold for mother-to-child transmission.

  1995cited by this paper
• A one-tube quantitative HIV-1 RNA NASBA nucleic acid amplification assay using electrochemiluminescent (ECL) labelled probes.

  1994cited by this paper
• Detection and biologic characterization of infectious HIV-1 in semen of seropositive men

  1994cited by this paper
• Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during therapy

  1994cited by this paper
• Resistance to 2',3'-dideoxycytidine conferred by a mutation in codon 65 of the human immunodeficiency virus type 1 reverse transcriptase

  1994cited by this paper
• Resistance of clinical isolates of human immunodeficiency virus to antiretroviral agents

  1993cited by this paper
• Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase.

  1993cited by this paper
• Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides

  1993cited by this paper
• Brief report: primary infection with zidovudine-resistant human immunodeficiency virus type 1.

  1993cited by this paper
• The same mutation that encodes low-level human immunodeficiency virus type 1 resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine confers high-level resistance to the (-) enantiomer of 2',3'-dideoxy-3'-thiacytidine

  1993cited by this paper
• Ordered appearance of zidovudine resistance mutations during treatment of 18 human immunodeficiency virus-positive subjects.

  1992cited by this paper
• Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine.

  1992cited by this paper
• Human immunodeficiency virus type 1 pol gene mutations which cause decreased susceptibility to 2',3'-dideoxycytidine

  1992cited by this paper
• CLUSTAL V: improved software for multiple sequence alignment

  1992cited by this paper
• Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT).

  1989cited by this paper
• Evaluation of the maximum likelihood estimate of the evolutionary tree topologies from DNA sequence data, and the branching order in hominoidea

  1989cited by this paper
• Concurrent zidovudine levels in semen and serum determined by radioimmunoassay in patients with AIDS or AIDS-related complex.

  1988cited by this paper
• The neighbor-joining method: a new method for reconstructing phylogenetic trees.

  1987cited by this paper
• CONFIDENCE LIMITS ON PHYLOGENIES: AN APPROACH USING THE BOOTSTRAP

  1985cited by this paper
• A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences

  1980cited by this paper

• Modeling the effects of cross immunity and control measures on competitive dynamics of SARS-CoV-2 variants in the USA, UK, and Brazil.

  2025cites this paper
• EFdA efficiently suppresses HIV replication in the male genital tract and prevents penile HIV acquisition

  2023cites this paper
• Different features identified by machine learning associated with the HIV compartmentalization in semen.

  2022cites this paper
• Mutations make pandemics worse or better: modeling SARS-CoV-2 variants and imperfect vaccination

  2022influential citation
• HIV Compartmentalization in Male Genital Tract: Relevance for Viral Eradication

  2021influential citation
• Transmission of HIV-1 drug resistance mutations within partner-pairs: A cross-sectional study of a primary HIV infection cohort

  2018cites this paper
• DYNAMICAL BEHAVIORS OF AN INFLUENZA EPIDEMIC MODEL WITH VIRUS MUTATION

  2018cites this paper
• Human Immunodeficiency Virus (HIV) Infection

  2018cites this paper
• HIV-1 Viral Load and Resistance in Genital Secretions in Patients Taking Protease-Inhibitor-Based Second-Line Therapy in Africa

  2017cites this paper
• HIV Trafficking Between Blood and Semen During Early Untreated HIV Infection

  2017cites this paper
• No Substantial Evidence for Sexual Transmission of Minority HIV Drug Resistance Mutations in Men Who Have Sex with Men

  2017cites this paper
• Latent TGF‐β1 is Compartmentalized Between Blood and Seminal Plasma of HIV‐Positive Men and Its Activation in Semen is Negatively Correlated with Viral Load and Immune Activation

  2015cites this paper
• HIV Reservoir Dynamics in the Face of Highly Active Antiretroviral Therapy

  2015cites this paper
• 121 – Epidemiology and Prevention of Acquired Immunodeficiency Syndrome and Human Immunodeficiency Virus Infection

  2015cites this paper
• Pharmacokinetics of Antiretrovirals in Genital Secretions and Anatomic Sites of HIV Transmission: Implications for HIV Prevention

  2014cites this paper
• Cerebrospinal fluid can be used for HIV genotyping when it fails in blood.

  2014cites this paper
• Virologic determinants of breast milk transmission of HIV-1.

  2012cites this paper
• Interplay between HIV-1 and Host Genetic Variation: A Snapshot into Its Impact on AIDS and Therapy Response

  2012cites this paper
• The Male Genital Tract in the Era of Highly Active Antiretroviral Therapy (HAART): Implication for Antioxidant Therapy

  2012cites this paper
• On the Dynamics of a Two-Strain Influenza Model with Isolation

  2012cites this paper
• The Male Genital Tract in the Era of Highly Active Antiretroviral Therapy (HAART): Implication for Antioxidant Therapy

  2012cites this paper
• The Male Genital Tract in the Era of Highly Active Antiretroviral Therapy (HAART): Implication for Antioxidant Therapy

  2012cites this paper
• Lopinavir/Ritonavir

  2012cites this paper
• HIV compartmentalization: a review on a clinically important phenomenon.

  2012cites this paper
• Antiviral agents and HIV prevention: controversies, conflicts, and consensus.

  2012cites this paper
• Antiretroviral Treatment Interruptions Predict Female Genital Shedding of Genotypically Resistant HIV-1 RNA

  2012cites this paper
• Immunopathology and Infectious Diseases Human Immunodeficiency Virus Infects Human Seminal Vesicles in Vitro and in Vivo

  2011cites this paper
• Genital Tract Sequestration of SIV following Acute Infection

  2011cites this paper
• Evolutionary mechanisms of retroviral persistence.

  2011cites this paper
• Is expanded HIV treatment preventing new infections? Impact of antiretroviral therapy on sexual risk behaviors in the developing world

  2011cites this paper
• Tissue-specific HIV-1 infection: why it matters.

  2011cites this paper
• Pharmacokinetics of Antiretroviral Drugs in Anatomical Sanctuary Sites: The Male and Female Genital Tract

  2011cites this paper
• Human immunodeficiency virus infects human seminal vesicles in vitro and in vivo.

  2011cites this paper
• Gonadotoxicity Evaluation of Oral Administration of Zidolam in Male Albino Rats

  2010cites this paper
• The HIV epidemic in the United States: a time for action. Introduction.

  2010cites this paper
• Antiretroviral therapy as HIV prevention: status and prospects.

  2010cites this paper
• Treatment to prevent transmission of HIV-1.

  2010cites this paper
• Chemoprophylaxis for HIV Prevention: New Opportunities and New Questions

  2010cites this paper
• Fertility control Human immunodeficiency virus serodiscordant couples on highly active antiretroviral therapies with undetectable viral load : conception by unprotected sexual intercourse or by assisted reproduction techniques ?

  2010cites this paper
• Cross-immunity in multi-strain infectious diseases.

  2010influential citation
• HIV-1 Populations in Semen Arise through Multiple Mechanisms

  2010cites this paper
• Human immunodeficiency virus serodiscordant couples on highly active antiretroviral therapies with undetectable viral load: conception by unprotected sexual intercourse or by assisted reproduction techniques?

  2010cites this paper
• HIV infection of the male genital tract – consequences for sexual transmission and reproduction

  2010influential citation
• Maraviroc Concentrates in the Cervicovaginal Fluid and Vaginal Tissue of HIV-Negative Women

  2009cites this paper
• Monotypic Human Immunodeficiency Virus Type 1 Genotypes across the Uterine Cervix and in Blood Suggest Proliferation of Cells with Provirus

  2009cites this paper
• Exploring the impact of target cell heterogeneity on HIV loads in a within-host model.

  2009cites this paper
• Determining Seminal Plasma Human Immunodeficiency Virus Type 1 Load in the Context of Efficient Highly Active Antiretroviral Therapy

  2009cites this paper
• Monotypic Human Immunodeficiency Virus Type 1 Genotypes across the Uterine Cervix and in Blood Suggest Proliferation of Cells with Provirus (cid:1)

  2009cites this paper
• Using antiretrovirals to prevent HIV transmission

  2009cites this paper
• Assays for the determination of HIV-1 load in semen: a review of indications, methods and performance in vitro.

  2008cites this paper
• The Pharmacokinetics and Viral Activity of Tenofovir in the Male Genital Tract

  2008cites this paper
• Article Commentary: HIV Transmission Hunting – the Chase for Low Risk Events

  2008cites this paper
• Human Immunodeficiency Virus Viral Load in Blood Plasma and Semen: Review and Implications of Empirical Findings

  2008cites this paper
• Differential Extracellular and Intracellular Concentrations of Zidovudine and Lamivudine in Semen and Plasma of HIV-1-Infected Men

  2008cites this paper
• IGA MEDIATED DEFENSES AGAINST HIV-1

  2008cites this paper
• Infection of Semen-Producing Organs by SIV during the Acute and Chronic Stages of the Disease

  2008cites this paper
• Correlation between HIV-1 RNA load in blood and seminal plasma depending on antiretroviral treatment status, regimen and penetration of semen by antiretroviral drugs.

  2008cites this paper
• Effect of Semen Sampling Frequency on Seminal Antiretroviral Drug Concentration

  2008cites this paper
• Persistent differences in the antiviral effects of highly active antiretroviral therapy in the blood and male genital tract.

  2008cites this paper
• Therapeutic monitoring is necessary for the association itraconazole and efavirenz in a patient with AIDS and disseminated histoplasmosis.

  2008cites this paper
• Narrative Review: Antiretroviral Therapy to Prevent the Sexual Transmission of HIV-1

  2007cites this paper
• Le tractus gnital masculin: un hte pour le VIH

  2007cites this paper
• Antiretroviral therapy : efficacy and toxicity in the ARES study and responses in the male genital tract

  2007cites this paper
• Transmitted Resistance: An Overview and Its Potential Relevance to the Management of HIV-Infected Persons in Resource-Limited Settings

  2007cites this paper
• Transmitted HIV-1 drug resistance: are we seeing just the tip of an epidemiological iceberg?

  2007cites this paper
• [The male genital tract: A host for HIV].

  2007cites this paper
• The Spread of HIV-1 Subtypes B and CRF01_AE Among Injecting Drug Users in Bangkok, Thailand

  2007cites this paper
• Quantification of antiretroviral drugs for HIV‐1 in the male genital tract: current data, limitations and implications for laboratory analysis

  2007cites this paper
• No Virological Failure in Semen During Properly Suppressive Antiretroviral Therapy Despite Subtherapeutic Local Drug Concentrations

  2006cites this paper
• Lower levels of HIV RNA in semen in HIV-2 compared with HIV-1 infection: implications for differences in transmission

  2006cites this paper
• Decreased semen volume and spermatozoa motility in HIV-1-infected patients under antiretroviral treatment.

  2006cites this paper
• Thomas Parran Award Lecture: Transmission and Prevention of Transmission of HIV-1

  2006cites this paper
• HIV-1 in genital compartments: vexing viral reservoirs

  2006cites this paper
• HIV transmission and primary drug resistance.

  2006cites this paper
• Penetration of didanosine in semen of HIV-1-infected men.

  2006cites this paper
• Role of the HIV/AIDS Case Manager: Analysis of a Case Management Adherence Training and Coordination Program in North Carolina

  2006cites this paper
• Undetectable viral load is associated with sexual risk taking in HIV serodiscordant gay couples in Sydney

  2005cites this paper
• HIV Treatment Meets Prevention: Antiretroviral Therapy as Prophylaxis

  2005cites this paper
• XENOBIOTIC AND ENDOBIOTIC TRANSPORTER MRNA EXPRESSION IN THE BLOOD-TESTIS BARRIER

  2005cites this paper
• Pathophysiology of HIV-1 in semen: current evidence for compartmentalisation and penetration by antiretroviral drugs.

  2005cites this paper
• Acute HIV Infection: Implications for HIV Spread, Disease Progression, and Vaccine Development

  2005cites this paper
• HIV in semen: Still more to be learned

  2005cites this paper
• Impact des inhibiteurs nucléosidiques de la transcriptase inverse sur l’ADN mitochondrial et génomique des spermatozoïdes lors de l’Assistance Médicale à la Procréation

  2004cites this paper
• [Conservation of human embryos in straws: safety in terms of human immunodeficiency virus 1].

  2004cites this paper
• Conservation en paillettes des gamètes et embryons humains : sécurité vis-à-vis du virus de type 1 de l'immunodéficience humaine

  2004cites this paper
• Differences between semen and plasma of nucleoside reverse transcriptase resistance mutations in HIV-infected patients, using a rapid assay.

  2004cites this paper
• Diminished Representation of HIV-1 Variants Containing Select Drug Resistance-Conferring Mutations in Primary HIV-1 Infection

  2004cites this paper
• Transmission of HIV-1 drug resistance.

  2004cites this paper
• Causes of HIV treatment failure

  2004cites this paper
• Evidence of genotypic resistance diversity of archived and circulating viral strains in blood and semen of pre-treated HIV-infected men

  2004cites this paper
• Risk management and harm reduction among gay men in Sydney

  2004cites this paper
• Offering HIV Post-Exposure Prophylaxis (PEP) Following Non-Occupational Exposures Recommendations for Health Care Providers in the State of California

  2004cites this paper
• Medically assisted reproduction in the presence of chronic viral diseases.

  2004cites this paper
• The role of sexually transmitted diseases in HIV transmission

  2004cites this paper
• Molecular characterization of HIV-1 Subtype C strains from KwaZulu-Natal, South Africa, with a special emphasis on viral fitness and drug resistance.

  2004cites this paper
• Epidemiological Models for Mutating Pathogens

  2004cites this paper
• Primary HIV infection as source of HIV transmission within steady and casual partnerships among homosexual men

  2004cites this paper
• XENOBIOTIC AND ENDOBIOTIC TRANSPORTER mRNA EXPRESSION IN

  2004cites this paper
• Is the male genital tract really a sanctuary site for HIV? Arguments that it is not.

  2004cites this paper
• Viruses in semen and male genital tissues--consequences for the reproductive system and therapeutic perspectives.

  2004cites this paper