Flexible modeling of the cumulative effects of time‐dependent exposures on the hazard

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Statistics in Medicine

• Publication date

  2009-11-30

• Fields of study

  Medicine, Mathematics

• Identifiers
  DOI 10.1002/sim.3701PMID 19708037
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Regression splines in the time‐dependent coefficient rates model for recurrent event data

  2008cited by this paper
• Comparison of algorithms to generate event times conditional on time‐dependent covariates

  2008cited by this paper
• Cardiovascular and respiratory hospitalizations and mortality among users of tiotropium in Denmark

  2007cited by this paper
• CAN ONE ESTIMATE THE UNCONDITIONAL DISTRIBUTION OF POST-MODEL-SELECTION ESTIMATORS?

  2007cited by this paper
• Joint estimation of time‐dependent and non‐linear effects of continuous covariates on survival

  2007cited by this paper
• Do Oscar Winners Live Longer than Less Successful Peers? A Reanalysis of the Evidence

  2006cited by this paper
• Selecting the Optimal Transformation of a Continuous Covariate in Cox's Regression: Implications for Hypothesis Testing

  2006cited by this paper
• Lifetime cumulative exposure to secondhand smoke and risk of myocardial infarction in never smokers: results from the Western New York health study, 1995-2001.

  2006cited by this paper
• Modeling cumulative dose and exposure duration provided insights regarding the associations between benzodiazepines and injuries.

  2006cited by this paper
• A 5‐Year Prospective Assessment of the Risk Associated with Individual Benzodiazepines and Doses in New Elderly Users

  2005cited by this paper
• A Varying‐Coefficient Cox Model for the Effect of Age at a Marker Event on Age at Menopause

  2005cited by this paper
• A review of uses of health care utilization databases for epidemiologic research on therapeutics.

  2005cited by this paper
• Survival bias associated with time-to-treatment initiation in drug effectiveness evaluation: a comparison of methods.

  2005cited by this paper
• Epidemiologic approaches to disasters: reducing our vulnerability.

  2005cited by this paper
• Longitudinal patterns of new Benzodiazepine use in the elderly

  2004cited by this paper
• Cholesterol lowering drugs and risk of age related maculopathy: prospective cohort study with cumulative exposure measurement

  2003cited by this paper
• Quantifying epidemiologic risk factors using non‐parametric regression: model selection remains the greatest challenge

  2003cited by this paper
• Effectiveness of inhaled corticosteroids in chronic obstructive pulmonary disease: immortal time bias in observational studies.

  2003cited by this paper
• Evaluating medication effects outside of clinical trials: new-user designs.

  2003cited by this paper
• Marginal and hazard ratio specific random data generation: Applications to semi-parametric bootstrapping

  2002cited by this paper
• Benzodiazepines and hip fractures in elderly people: case-control study

  2001cited by this paper
• Bayesian Information Criterion for Censored Survival Models

  2000cited by this paper
• Analysis of Exposure‐Time‐Response Relationships Using a Spline Weight Function

  2000cited by this paper
• Assessing the effect of intensity when exposure varies over time.

  1997cited by this paper
• Time-Dependent Hazard Ratio: Modeling and Hypothesis Testing with Application in Lupus Nephritis

  1996cited by this paper
• Applying Cox regression to competing risks.

  1995cited by this paper
• Varying‐Coefficient Models

  1993cited by this paper
• Flexible Methods for Analyzing Survival Data Using Splines, with Applications to Breast Cancer Prognosis

  1992cited by this paper
• Nonparametric density estimation for censored survival data: Regression‐spline approach

  1992cited by this paper
• The impact of model selection on inference in linear regression

  1990cited by this paper
• Monotone Regression Splines in Action

  1988cited by this paper
• Models for exposure-time-response relationships with applications to cancer epidemiology.

  1988cited by this paper
• [Generalized Additive Models]: Comment

  1986cited by this paper
• Multiplicative Models and Cohort Analysis

  1983cited by this paper
• Splines as a Useful and Convenient Statistical Tool

  1979cited by this paper
• Asbestosis: a study of dose-response relationships in an asbestos textile factory

  1979cited by this paper
• Estimating the Dimension of a Model

  1978cited by this paper
• Regression models and life tables (with discussion

  1972cited by this paper
• Regression Models and Life-Tables

  1972cited by this paper
• © 1999 Cancer Research Campaign Article no. bjoc.1999.0651 Colorectal cancer prevention by non-steroidal anti-inflammatory drugs: effects of dosage and timing

  year unknowncited by this paper

• Corticosteroid Use and Risk of Adverse Events in Metastatic Hormone-Sensitive Prostate Cancer.

  2026cites this paper
• Caution: Time-Varying Exposures Ahead.

  2026cites this paper
• Utility and anxiety in AI use: How train drivers make sense of AI adoption and what it means for railway safety

  2025cites this paper
• Keeping It Simple: The Use of a Weighted Cumulative Exposure to Examine the Relationship Between Severe Maternal Morbidity and Health Outcomes.

  2025cites this paper
• Weighted Cumulative Exposure Modelling to Assess the Association Between Reproductive Factors and Future Cardiovascular Disease in Women.

  2025cites this paper
• Time-Varying Associations Between Physical Activity and Injury Risk Among Children.

  2025cites this paper
• A lifetime of experiences: Modelling habitat quality through cumulative effects on individual survival

  2025cites this paper
• Wavelet‐Mixed Landmark Survival Models for the Effect of Short‐Term Changes of Potassium in Heart Failure Patients

  2025cites this paper
• Second primary cancers and hormonal therapies for prostate cancer: A nested case–control study

  2025cites this paper
• Estimating associations between cumulative exposure and health via generalized distributed lag non-linear models using penalized splines.

  2025cites this paper
• Joint modeling of longitudinal CD4 count data and time to first occurrence of composite outcome

  2024cites this paper
• A guide to improving the design and analysis of observational studies on the long-term safety of topical corticosteroids.

  2024cites this paper
• Questioning a Sensible Result.

  2024cites this paper
• Impact of airborne particulate matter exposure on hospital admission for Alzheimer's disease and the attributable economic burden: evidence from a time-series study in Sichuan, China

  2024cites this paper
• A Bayesian functional approach to test models of life course epidemiology over continuous time

  2024cites this paper
• Immunosuppression and cancer risk in kidney transplant recipients: A retrospective cohort study

  2024cites this paper
• The accumulated impact of critical incident exposure on correctional officers’ mental health

  2024cites this paper
• Delayed kernels for longitudinal survival analysis and dynamic prediction

  2024cites this paper
• Weighted biomarker variability in joint analysis of longitudinal and time-to-event data

  2024cites this paper
• Dynamic Prediction Using Landmark Historical Functional Cox Regression

  2024cites this paper
• The accumulated impact of direct and indirect workplace violence exposure on mental health and physiological activity among correctional officers

  2024cites this paper
• Predicted 25-hydroxyvitamin D over the adult lifetime and the risk of ovarian cancer

  2024cites this paper
• Impact of anti-VEGF treatment for diabetic macular oedema on progression to proliferative diabetic retinopathy: data-driven insights from a multicentre study

  2023cites this paper
• Drug dosage modifications in 24 million in-patient prescriptions covering eight years: A Danish population-wide study of polypharmacy

  2023cites this paper
• Flexible parametrization of graph‐theoretical features from individual‐specific networks for prediction

  2023cites this paper
• Importance of accounting for timing of time‐varying exposures in association studies: Hydrochlorothiazide and non‐melanoma skin cancer

  2023influential citation
• Reverse causation biases weighted cumulative exposure model estimates, but can be investigated in sensitivity analyses.

  2023cites this paper
• Modeling biomarker variability in joint analysis of longitudinal and time-to-event data

  2023cites this paper
• Comparison of Different Modeling Approaches for Prescription Opioid Use and Its Association With Adverse Events

  2023cites this paper
• The Application of Lag Times in Cancer Pharmacoepidemiology: A Narrative Review.

  2023cites this paper
• Comparison of cohort and nested case‐control designs for estimating the effect of time‐varying drug exposure on the risk of adverse event in the presence of ties

  2023cites this paper
• ESTIMATION AND INFERENCE FOR EXPOSURE EFFECTS WITH LATENCY IN THE COX PROPORTIONAL HAZARDS MODEL IN THE PRESENCE OF EXPOSURE MEASUREMENT ERROR.

  2023cites this paper
• Assessing cumulative effects of medication use: New insights and new challenges

  2023influential citation
• Measures of Longitudinal Immune Dysfunction and Risk of AIDS and Non-AIDS Defining Malignancies in Antiretroviral-Treated People With Human Immunodeficiency Virus

  2023cites this paper
• Are patients with primary glomerular disease at increased risk of malignancy?

  2023cites this paper
• Temporal effect of imatinib adherence on time to remission in chronic myeloid leukemia patients

  2023cites this paper
• The weighted cumulative exposure method and its application to pharmacoepidemiology: A narrative review

  2023influential citation
• The association between exacerbation of chronic obstructive pulmonary disease and timing of paracetamol use: a cohort study in elderly Australians

  2022cites this paper
• Opioid Drug-Drug-Drug Interactions and Unintentional Traumatic Injury: Screening to Detect Three-Way Drug Interaction Signals

  2022cites this paper
• A competing risks regression model for the association between time-varying opioid exposure and risk of overdose

  2022cites this paper
• Assessing the cumulative effect of long-term training load on the risk of injury in team sports

  2022cites this paper
• Association of Prenatal Exposure to Benzodiazepines With Development of Autism Spectrum and Attention-Deficit/Hyperactivity Disorders

  2022cites this paper
• A data-driven pipeline to extract potential adverse drug reactions through prescription, procedures and medical diagnoses analysis: application to a cohort study of 2,010 patients taking hydroxychloroquine with an 11-year follow-up

  2022cites this paper
• Adapting SIMEX to correct for bias due to interval‐censored outcomes in survival analysis with time‐varying exposure

  2022cites this paper
• Protein intake and outcome of critically ill patients: analysis of a large international database using piece-wise exponential additive mixed models

  2022cites this paper
• Positive impact on 10-year outcome of the window of opportunity for conventional synthetic DMARDs in rheumatoid arthritis: results from the ESPOIR cohort

  2022cites this paper
• Metformin Treatment Among Men With Diabetes and the Risk of Prostate Cancer: A Population-Based Historical Cohort Study

  2021cites this paper
• Assessing long-term effectiveness of MS treatment — a matter of debate

  2021cites this paper
• Equity and the JAMA Network.

  2021cites this paper
• Long-term brain network reorganization predicts responsive neurostimulation outcomes for focal epilepsy

  2021cites this paper
• Association of Enzyme-Inducing Antiseizure Drug Use With Long-term Cardiovascular Disease.

  2021cites this paper
• Evaluating Montréal’s harm reduction interventions for people who inject drugs: protocol for observational study and cost-effectiveness analysis

  2021cites this paper
• Impact of time-varying cumulative bevacizumab exposures on survival: re-analysis of data from randomized clinical trial in patients with metastatic colo-rectal cancer

  2021cites this paper
• Latency of tobacco smoking for head and neck cancer among HPV‐positive and HPV‐negative individuals

  2020cites this paper
• Imputing missing time-dependent covariate values for the discrete time Cox model

  2020cites this paper
• Modeling of cumulative effects of time-varying drug exposures on within-subject changes in a continuous outcome

  2020influential citation
• Nonlinear and time‐dependent effects of sparsely measured continuous time‐varying covariates in time‐to‐event analysis

  2020cites this paper
• Constructing treatment episodes from concomitant medication logs: a prospective observational study

  2020cites this paper
• A Cautionary Note on Extended Kaplan-Meier Curves for Time-varying Covariates.

  2020cites this paper
• Lagged WQS regression for mixtures with many components

  2020cites this paper
• Determination of the time-dependent association between ciprofloxacin consumption and ciprofloxacin resistance using a weighted cumulative exposure model compared with standard models.

  2020cites this paper
• Psychosocial work exposures of the job strain model and cardiovascular mortality in France: results from the STRESSJEM prospective study

  2020cites this paper
• Analysis of time‐to‐event for observational studies: Guidance to the use of intensity models

  2020cites this paper
• The impact of employment on recovery among individuals who are homeless with severe mental illness in the Vancouver At Home/Chez Soi trial

  2020cites this paper
• Time-varying associations between an exposure history and a subsequent health outcome: a landmark approach to identify critical windows

  2020cites this paper
• Latency estimation for chronic disease risk: a damped exponential weighting model

  2020cites this paper
• Joint modeling of time-varying exposure history and subsequent health outcomes: identification of critical windows

  2020influential citation
• Modelling of heat stress in a robotic dairy farm. Part 4: Time constant and cumulative effects of heat stress

  2020cites this paper
• The Risk of Cardiovascular Events Associated With Disease-modifying Antirheumatic Drugs in Rheumatoid Arthritis

  2020cites this paper
• Evaluating the intended and unintended consequences of opioid-prescribing interventions on primary care in British Columbia, Canada: protocol for a retrospective population-based cohort study

  2020cites this paper
• Classification of drug use patterns

  2020cites this paper
• Nurse staffing practices and adverse events in acute care hospitals: The research protocol of a multisite patient‐level longitudinal study

  2020influential citation
• The dynamic effect of direct‐acting antiviral treatments on the risk of hepatocellular carcinoma in patients with cirrhosis and chronic hepatitis C

  2019cites this paper
• Penalized estimation of complex, non‐linear exposure‐lag‐response associations

  2019cites this paper
• Competing risks modeling of cumulative effects of time-varying drug exposures

  2019cites this paper
• Comparaison par simulations de modèles de survie pour la prise en compte de l’effet cumulé d’une exposition longitudinale

  2019cites this paper
• Risks and Benefits of Attention-Deficit/Hyperactivity Disorder Medication on Behavioral and Neuropsychiatric Outcomes: A Qualitative Review of Pharmacoepidemiology Studies Using Linked Prescription Databases.

  2019cites this paper
• Flexible Modeling of the Association Between Cumulative Exposure to Low-Dose Ionizing Radiation from Cardiac Procedures and the Malignancy Risk in Adults with Congenital Heart Disease.

  2019cites this paper
• Using flexible methods to determine risk factors for ventilator-associated pneumonia in the Netherlands

  2019cites this paper
• Metformin Treatment and Cancer Risk: Cox Regression Analysis, With Time-Dependent Covariates, of 320,000 Persons With Incident Diabetes Mellitus

  2019influential citation
• Clinical Nutrition in Critical Care Medicine - Guideline of the German Society for Nutritional Medicine (DGEM).

  2019cites this paper
• Risk of Serious Infection in Patients With Rheumatoid Arthritis Treated With Biologic Versus Nonbiologic Disease‐Modifying Antirheumatic Drugs

  2019cites this paper
• Prospective associations of psychosocial work exposures with mortality in France: STRESSJEM study protocol

  2019cites this paper
• DGEM-Leitlinie: „Klinische Ernährung in der Intensivmedizin“

  2018cites this paper
• Risk of acute myocardial infarction with real‐world NSAIDs depends on dose and timing of exposure

  2018cites this paper
• Modeling time‐varying exposure using inverse probability of treatment weights

  2018cites this paper
• Prediction of Drug-Related Risks Using Clinical Context Information in Longitudinal Claims Data.

  2018cites this paper
• The limitations of using simple definitions of glucocorticoid exposure to predict fracture risk: A cohort study

  2018cites this paper
• Acute vs cumulative benefits of metformin use in patients with type 2 diabetes and heart failure

  2018cites this paper
• A Bayesian approach to investigate life course hypotheses involving continuous exposures

  2018cites this paper
• Effect of cumulative exposure to corticosteroid and DMARD on radiographic progression in rheumatoid arthritis: results from the ESPOIR cohort

  2018cites this paper
• Time-dependent effect of intensity of smoking and of occupational exposure to asbestos on the risk of lung cancer: results from the ICARE case–control study

  2018cites this paper
• Methods for time‐varying exposure related problems in pharmacoepidemiology: An overview

  2017cites this paper
• Risk of acute myocardial infarction with NSAIDs in real world use: bayesian meta-analysis of individual patient data

  2017cites this paper
• Dose-time-response association between occupational asbestos exposure and pleural mesothelioma

  2017cites this paper
• A penalized framework for distributed lag non‐linear models

  2017cites this paper
• Using Multiple Pharmacovigilance Models Improves the Timeliness of Signal Detection in Simulated Prospective Surveillance

  2017cites this paper
• Does the association between adherence to statin medications and mortality depend on measurement approach? A retrospective cohort study

  2017cites this paper
• Extension of the association structure in joint models to include weighted cumulative effects

  2017cites this paper
• Quantifying risk over the life course – latency, age‐related susceptibility, and other time‐varying exposure metrics

  2016cites this paper