A common mechanism for mitotic inactivation of C2H2 zinc finger DNA-binding domains.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Genes & Development

• Publication date

  2002-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1101/GAD.1040502PMID 12464629PMCID PMC187490
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2000influential reference
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  1999cited by this paper
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  1999influential reference
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  1997cited by this paper
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  1987influential reference
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  1962cited by this paper

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