Regulation of Alternative Polyadenylation by U1 snRNPs and SRp20

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Molecular and Cellular Biology

• Publication date

  1998-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/MCB.18.9.4977PMID 9710581PMCID PMC109082
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase.

  1998cited by this paper
• Human pre-mRNA cleavage factor Im is related to spliceosomal SR proteins and can be reconstituted in vitro from recombinant subunits.

  1998cited by this paper
• Transcription units as RNA processing units.

  1997cited by this paper
• Distribution of pre-mRNA splicing factors at sites of RNA polymerase II transcription.

  1997cited by this paper
• Alternative poly(A) site selection in complex transcription units: means to an end?

  1997cited by this paper
• 5'-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II.

  1997cited by this paper
• Mechanism and regulation of mRNA polyadenylation.

  1997cited by this paper
• The C-terminal domain of RNA polymerase II couples mRNA processing to transcription

  1997cited by this paper
• Transcription factor TFIID recruits factor CPSF for formation of 3′ end of mRNA

  1997cited by this paper
• Control of alternative pre-mRNA splicing by distributed pentameric repeats.

  1997cited by this paper
• The HIV‐1 5′ LTR poly(A) site is inactivated by U1 snRNP interaction with the downstream major splice donor site

  1997cited by this paper
• The splicing factor SRp20 modifies splicing of its own mRNA and ASF/SF2 antagonizes this regulation

  1997cited by this paper
• mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain.

  1997cited by this paper
• Role of the Modular Domains of SR Proteins in Subnuclear Localization and Alternative Splicing Specificity

  1997cited by this paper
• Regulated expression and RNA processing of transcripts from the Srp20 splicing factor gene during the cell cycle

  1997cited by this paper
• Involvement of the carboxyl terminus of vertebrate poly(A) polymerase in U1A autoregulation and in the coupling of splicing and polyadenylation.

  1997cited by this paper
• A hyperphosphorylated form of the large subunit of RNA polymerase II is associated with splicing complexes and the nuclear matrix.

  1996cited by this paper
• Functional properties of p54, a novel SR protein active in constitutive and alternative splicing

  1996cited by this paper
• The biochemistry of polyadenylation.

  1996cited by this paper
• Interaction between the U1 snRNP-A protein and the 160-kD subunit of cleavage-polyadenylation specificity factor increases polyadenylation efficiency in vitro.

  1996cited by this paper
• The SR protein family: pleiotropic functions in pre-mRNA splicing.

  1996cited by this paper
• The cap and the 3' splice site similarly affect polyadenylation efficiency

  1996cited by this paper
• The polyadenylation factor CstF-64 regulates alternative processing of IgM heavy chain pre-mRNA during B cell differentiation.

  1996cited by this paper
• An intron enhancer recognized by splicing factors activates polyadenylation.

  1996cited by this paper
• The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins.

  1996cited by this paper
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  1996cited by this paper
• SR proteins and splicing control.

  1996cited by this paper
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  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
• Poly(A) site selection in the HIV-1 provirus: inhibition of promoter-proximal polyadenylation by the downstream major splice donor site.

  1995cited by this paper
• A 32-nucleotide exon-splicing enhancer regulates usage of competing 5' splice sites in a differential internal exon

  1995cited by this paper
• An intron enhancer containing a 5' splice site sequence in the human calcitonin/calcitonin gene-related peptide gene

  1995cited by this paper
• New proteins related to the Ser-Arg family of splicing factors.

  1995cited by this paper
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  1995cited by this paper
• Regulation of poly(A) site use during mouse B-cell development involves a change in the binding of a general polyadenylation factor in a B-cell stage-specific manner

  1995cited by this paper
• The 64-kilodalton subunit of the CstF polyadenylation factor binds to pre-mRNAs downstream of the cleavage site and influences cleavage site location

  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
• The calcitonin exon and its flanking intronic sequences are sufficient for the regulation of human calcitonin/calcitonin gene-related peptide alternative RNA splicing.

  1994cited by this paper
• Sequences homologous to 5' splice sites are required for the inhibitory activity of papillomavirus late 3' untranslated regions

  1994cited by this paper
• Two different sequence elements within exon 4 are necessary for calcitonin-specific splicing of the human calcitonin/calcitonin gene-related peptide I pre-mRNA

  1994cited by this paper
• Protein–protein interactions and 5'-splice-site recognition in mammalian mRNA precursors

  1994cited by this paper
• Direct interaction of the U1 snRNP-A protein with the upstream efficiency element of the SV40 late polyadenylation signal.

  1994cited by this paper
• Specific interactions between proteins implicated in splice site selection and regulated alternative splicing.

  1993cited by this paper
• Functional analysis of pre‐mRNA splicing factor SF2/ASF structural domains.

  1993cited by this paper
• Evidence for two active sites in the spliceosome provided by stereochemistry of pre-mRNA splicing

  1993cited by this paper
• Distinct functions of SR proteins in alternative pre-mRNA splicing.

  1993cited by this paper
• The mechanism of somatic inhibition of Drosophila P-element pre-mRNA splicing: multiprotein complexes at an exon pseudo-5' splice site control U1 snRNP binding.

  1992cited by this paper
• Identification of exon sequences and an exon binding protein involved in alternative RNA splicing of calcitonin/CGRP.

  1992cited by this paper
• SR proteins: a conserved family of pre-mRNA splicing factors.

  1992cited by this paper
• A differentially expressed murine RNA encoding a protein with similarities to two types of nucleic acid binding motifs.

  1991cited by this paper
• Mutation of the AAUAAA polyadenylation signal depresses in vitro splicing of proximal but not distal introns.

  1991cited by this paper
• Purification and characterization of pre-mRNA splicing factor SF2 from HeLa cells.

  1990cited by this paper
• In vitro polyadenylation is stimulated by the presence of an upstream intron.

  1990cited by this paper
• The essential pre-mRNA splicing factor SF2 influences 5' splice site selection by activating proximal sites.

  1990cited by this paper
• A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro.

  1990cited by this paper
• Multiple factors are required for specific RNA cleavage at a poly(A) addition site.

  1988cited by this paper
• Neuron-specific alternative RNA processing in transgenic mice expressing a metallothionein-calcitonin fusion gene.

  1987cited by this paper
• A compensatory base change in U1 snRNA suppresses a 5' splice site mutation.

  1986cited by this paper
• Alternative RNA processing: determining neuronal phenotype.

  1984cited by this paper
• Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei.

  1983influential reference
• Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products

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• Regulation of polyadenylation site choice in plant nuclear mRNA

  2025cites this paper
• The competition between splicing and 3′ processing shapes the human transcriptome

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• Oncogenic SRSF3 in health and diseases

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• SRSF3 and SRSF7 modulate 3′UTR length through suppression or activation of proximal polyadenylation sites and regulation of CFIm levels

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