Intracellular nucleotides and polyamines inhibit the Ca2+-activated cation channel TRPM4b

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Pflügers Archiv

• Publication date

  2004-01-31

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1007/s00424-003-1221-xPMID 14758478
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Reduction of ionic strength activates single volume-regulated anion channels (VRAC) in endothelial cells

  2014cited by this paper
• Mg2+-dependent Gating and Strong Inward Rectification of the Cation Channel TRPV6

  2003cited by this paper
• Regulation by voltage and adenine nucleotides of a Ca2+‐activated cation channel from hamster vomeronasal sensory neurons

  2003cited by this paper
• Polyvalent cations as permeant probes of MIC and TRPM7 pores.

  2003cited by this paper
• TRPM5 is a transient Ca2+-activated cation channel responding to rapid changes in [Ca2+]i

  2003cited by this paper
• Subunit-Dependent Modulation of Kainate Receptors by Extracellular Protons and Polyamines

  2003cited by this paper
• Voltage Dependence of the Ca2+-activated Cation Channel TRPM4*

  2003cited by this paper
• Molecular Determinants of Permeation through the Cation Channel TRPV4*

  2002cited by this paper
• Current understanding of mammalian TRP homologues.

  2002cited by this paper
• TRPM4 Is a Ca2 -Activated Nonselective Cation Channel Mediating Cell Membrane Depolarization

  2002influential reference
• A mechanogated nonselective cation channel in proximal tubule that is ATP sensitive.

  2002cited by this paper
• Characterization of a Ca2+-activated Nonselective Cation Channel during Dedifferentiation of Cultured Rat Ventricular Cardiomyocytes

  2002cited by this paper
• Adenosine 5?-Monophosphate Is a Selective Inhibitor of the Brown Adipocyte Nonselective Cation Channel

  2002cited by this paper
• ATP and nitric oxide modulate a Ca2+-activated non-selective cation current in macrovascular endothelial cells

  2002cited by this paper
• Control of rectification and permeation by two distinct sites after the second transmembrane region in Kir2.1 K+ channel

  2001cited by this paper
• CaT1 and the Calcium Release-activated Calcium Channel Manifest Distinct Pore Properties*

  2001cited by this paper
• Modulation of the epithelial calcium channel, ECaC, by intracellular Ca2+.

  2001cited by this paper
• The trp ion channel family

  2001cited by this paper
• Pharmacological modulation of monovalent cation currents through the epithelial Ca2+ channel ECaC1

  2001cited by this paper
• Block of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by polyamines and polyamine toxins.

  1996cited by this paper
• [K+] dependence of polyamine-induced rectification in inward rectifier potassium channels (IRK1, Kir2.1)

  1996cited by this paper
• Extracellular and intracellular effects of polyamines on smooth muscle contractions.

  1995cited by this paper

• Multidimensional pan cancer analysis of the sodium induced cell death gene TRPM4

  2025cites this paper
• Transient Receptor Potential channels (TRP) in GtoPdb v.2025.4

  2025cites this paper
• The Role of Metabolites in Cell–Cell Communication: A Review of Databases and Computational Tools

  2025cites this paper
• Persistent activation of TRPM4 triggers necrotic cell death characterized by sodium overload

  2025cites this paper
• Mechanisms of dual modulatory effects of spermine on the mitochondrial calcium uniporter complex

  2025cites this paper
• The TRP Channels Serving as Chemical-to-Electrical Signal Converter.

  2025cites this paper
• Ion channels in respiratory rhythm generation and sensorimotor integration.

  2025cites this paper
• Structural landscape of activation, desensitization and inhibition in the human TRPM4 channel

  2025cites this paper
• Necrotic cell death through sodium overload provides a potential mechanism against neurodegenerative diseases.

  2025cites this paper
• Molecular basis of TRPV3 channel blockade by intracellular polyamines

  2025cites this paper
• Targeting the TRPM4 Channel for Neurologic Diseases: Opportunity and Challenge

  2025cites this paper
• Physiological temperature drives TRPM4 ligand recognition and gating

  2024influential citation
• Transient Receptor Potential (TRP) Channels in Cochlear Function: Looking Beyond Mechanotransduction

  2024cites this paper
• TRPM3, TRPM4, and TRPM5 as thermo-sensitive channels

  2024cites this paper
• Hyperosmolality activates polycystin-2 and TRPM4 in renal primary cilium

  2024cites this paper
• Blockade of TRPV channels by intracellular spermine

  2023cites this paper
• Transient Receptor Potential channels (TRP) in GtoPdb v.2023.2

  2023cites this paper
• Knockdown of the TRPM4 channel alters cardiac electrophysiology and hemodynamics in a sex‐ and age‐dependent manner in mice

  2023cites this paper
• Plasma Membrane Channel TRPM4 Mediates Immunogenic Therapy-Induced Necrosis.

  2023cites this paper
• Handbook of Ion Channels

  2023cites this paper
• Mechanisms of dual modulatory effects of spermine on the mitochondrial calcium uniporter complex

  2023cites this paper
• New Drug Targets and Preclinical Modelling Recommendations for Treating Acute Myocardial Infarction.

  2023cites this paper
• Transient Receptor Potential channels (TRP) in GtoPdb v.2023.1

  2023cites this paper
• Exploring the role of TRPM4 in calcium‐dependent triggered activity and cardiac arrhythmias

  2023cites this paper
• TRPM4 Participates in Irradiation-Induced Aortic Valve Remodeling in Mice

  2022cites this paper
• Knockdown of the TRPM4 channel alters cardiac electrophysiology and hemodynamics in a sex- and age-dependent manner in mice

  2022cites this paper
• Pharmacological Modulation and (Patho)Physiological Roles of TRPM4 Channel—Part 1: Modulation of TRPM4

  2022influential citation
• A glibenclamide-sensitive TRPM4-mediated component of CA1 excitatory postsynaptic potentials appears in experimental autoimmune encephalomyelitis

  2022cites this paper
• Transient Receptor Potential channels (TRP) in GtoPdb v.2022.1

  2022cites this paper
• Cell death modulation by transient receptor potential melastatin channels TRPM2 and TRPM7 and their underlying molecular mechanisms.

  2021cites this paper
• Electrophysiological Effects of the Transient Receptor Potential Melastatin 4 Channel Inhibitor (4-Chloro-2-(2-chlorophenoxy)acetamido) Benzoic Acid (CBA) in Canine Left Ventricular Cardiomyocytes

  2021cites this paper
• Viewpoints on the Role of Transient Receptor Potential Melastatin Channels in Cardiovascular System and disease: A Systematic Review.

  2021cites this paper
• Glibenclamide Directly Prevents Neuroinflammation by Targeting SUR1-TRPM4-Mediated NLRP3 Inflammasome Activation In Microglia

  2021cites this paper
• Glibenclamide Directly Prevents Neuroin�ammation by Targeting SUR1-TRPM4-Mediated NLRP3 In�ammasome Activation in Microglia

  2021cites this paper
• Upregulation of transient receptor potential melastatin 4 (TRPM4) in ventricular fibroblasts from heart failure patients

  2021cites this paper
• Deletion of Trpm4 Alters the Function of the Nav1.5 Channel in Murine Cardiac Myocytes

  2021cites this paper
• Systematic Understanding of Pathophysiological Mechanisms of Oxidative Stress-Related Conditions—Diabetes Mellitus, Cardiovascular Diseases, and Ischemia–Reperfusion Injury

  2021cites this paper
• TRPM4 Conductances in Thalamic Reticular Nucleus Neurons Generate Persistent Firing during Slow Oscillations

  2020cites this paper
• conductances in thalamic reticular nucleus neurons generate persistent firing 1 during slow oscillations 2 Abbreviated title : TRPM 4 mediates PF in TRN

  2020cites this paper
• Molecular Regulations and Functions of the Transient Receptor Potential Channels of the Islets of Langerhans and Insulinoma Cells

  2020cites this paper
• TRPM4 modulates right ventricular remodeling under pressure load accompanied with decreased expression level.

  2020cites this paper
• Deletion of Trpm4 alters the function and expression of NaV1.5 channel in murine cardiac myocytes

  2020cites this paper
• TRPM Channels in Human Diseases

  2020influential citation
• Transient Receptor Potential channels (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

  2019cites this paper
• Trpm4 ion channels in pre-Bötzinger complex interneurons are essential for breathing motor pattern but not rhythm

  2019cites this paper
• Transient receptor potential channels in cardiac health and disease

  2019cites this paper
• TRP ion channels: Proteins with conformational flexibility

  2019cites this paper
• 2019 HRS expert consensus statement on evaluation, risk stratification, and management of arrhythmogenic cardiomyopathy.

  2019cites this paper
• Transient receptor potential melastatin 4 contributes to early-stage endothelial injury induced by arsenic trioxide.

  2019cites this paper
• Identification and classification of a new TRPM3 variant (γ subtype)

  2019cites this paper
• Shared CaM‐ and S100A1‐binding epitopes in the distal TRPM4 N terminus

  2018cites this paper
• Structure of full-length human TRPM4

  2018cites this paper
• Transient Receptor Potential Melastatin 4 Induces Astrocyte Swelling But Not Death after Diffuse Traumatic Brain Injury

  2018cites this paper
• Neuropathic Pain: Delving into the Oxidative Origin and the Possible Implication of Transient Receptor Potential Channels

  2018cites this paper
• Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation

  2018cites this paper
• TRPM4 activation by chemically- and oxygen deprivation-induced ischemia and reperfusion triggers neuronal death

  2017cites this paper
• Studies on molecular mechanisms in calcium signaling and cellular energy consumption

  2017cites this paper
• Respiratory Rhythm Generation: The Whole Is Greater Than the Sum of the Parts.

  2017cites this paper
• Structures of the Calcium-activated Non-Selective Cation Channel TRPM4

  2017cites this paper
• Smooth Muscle Ion Channels and Regulation of Vascular Tone in Resistance Arteries and Arterioles.

  2017cites this paper
• Uncovering the arrhythmogenic potential of TRPM4 activation in atrial-derived HL-1 cells using novel recording and numerical approaches

  2017cites this paper
• Transient receptor potential melastatin 4 cation channel in pediatric heart block.

  2017cites this paper
• Instructions for use Title Negatively Charged Amino Acids Near and in Transient Receptor Potential ( TRP ) Domain of TRPM 4 Channel Are One Determinant of Its Ca 2 + Sensitivity

  2016cites this paper
• TRPM4 non‐selective cation channels influence action potentials in rabbit Purkinje fibres

  2016cites this paper
• argets of polyamine dysregulation in major depression and suicide : ctivity-dependent feedback , excitability , and neurotransmission

  2016cites this paper
• Structural and Functional Characterisation of Heterologously Expressed Human Transient Receptor Potential Cation Channel, Subfamily M, Member 4 (TRPM4)

  2016influential citation
• Channels and Volume Changes in the Life and Death of the Cell

  2016cites this paper
• A TRPM4-dependent current in murine renal primary cilia.

  2015cites this paper
• Mechanisms Controlling Stem Cell Differentiation

  2015cites this paper
• TRPM4 in cardiac electrical activity.

  2015cites this paper
• from Background Currents Physiological Roles of the TRPM4 Channel Extracted

  2015cites this paper
• Enhanced β-adrenergic cardiac reserve in Trpm4⁻/⁻ mice with ischaemic heart failure.

  2015cites this paper
• Biophysical and Molecular Features of Thermosensitive TRP Channels Involved in Sensory Transduction

  2015cites this paper
• TRP Channels in the Sensation of Heat

  2015cites this paper
• Negatively Charged Amino Acids Near and in Transient Receptor Potential (TRP) Domain of TRPM4 Channel Are One Determinant of Its Ca2+ Sensitivity*

  2014cites this paper
• Glycosylation of TRPM4 and TRPM5 channels: molecular determinants and functional aspects

  2014influential citation
• Molecular Mechanisms Involved In The Generation Of Calcium Signals In Insulin Secreting Cells.

  2014cites this paper
• The TRPM4 channel inhibitor 9‐phenanthrol

  2014cites this paper
• Glycosylation of TRPM 4 and TRPM 5 channels : molecular determinants and functional aspects

  2014cites this paper
• Regulation of Cerebral Artery Smooth Muscle Membrane Potential by Ca2+‐Activated Cation Channels

  2013cites this paper
• Calmodulin and calmodulin kinase II mediate emergent bursting activity in the brainstem respiratory network (preBötzinger complex)

  2013cites this paper
• Biochemical, single-channel, whole-cell patch clamp, and pharmacological analyses of endogenous TRPM4 channels in HEK293 cells.

  2013cites this paper
• Oxidative stress-modulated TRPM ion channels in cell dysfunction and pathological conditions in humans.

  2013cites this paper
• The TRPM4 non-selective cation channel contributes to the mammalian atrial action potential.

  2013cites this paper
• Transient Receptor Potential Melastatin 4 Channel Controls Calcium Signals and Dental Follicle Stem Cell Differentiation

  2013cites this paper
• Elevated polyamines in urothelial cells from OAB subjects mediate oxotremorine-evoked rapid intracellular calcium rise and delayed acetylcholine release.

  2013cites this paper
• TRPM4 channels in smooth muscle function

  2013cites this paper
• TRPM4 channels in the cardiovascular system: physiology, pathophysiology, and pharmacology.

  2012cites this paper
• Sulfonylurea receptor 1 in central nervous system injury: a focused review

  2012cites this paper
• Transient receptor potential melastatin 4 and cell death

  2012cites this paper
• TMEM16F forms a Ca2+-activated cation channel required for lipid scrambling in platelets during blood coagulation.

  2012cites this paper
• On Potential Interactions between Non-selective Cation Channel TRPM4 and Sulfonylurea Receptor SUR1*

  2012cites this paper
• Endogenous cytosolic Ca(2+) buffering is necessary for TRPM4 activity in cerebral artery smooth muscle cells.

  2012cites this paper
• The Pathophysiological Implications of TRP Channels in Cardiac Arrhythmia

  2012cites this paper
• TRPs to Cardiovascular Disease

  2012cites this paper
• Determination of clonal pattern and the role of TRPM2/TRPM7 ion channels in malignant mesothelioma

  2012cites this paper
• The Ca 2+-Activated Monovalent Cation-Selective Channels TRPM4 and TRPM5

  2012cites this paper
• TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis

  2012cites this paper
• The non-selective monovalent cationic channels TRPM4 and TRPM5.

  2011influential citation
• TRP channels of islets.

  2011cites this paper