Identification of C/EBP basic region residues involved in DNA sequence recognition and half-site spacing preference

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Molecular and Cellular Biology

• Publication date

  1993-11-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1128/mcb.13.11.6919-6930.1993PMID 8413284PMCID PMC364754
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Identification of three residues in the basic regions of the bZIP proteins GCN4, C/EBP and TAF‐1 that are involved in specific DNA binding.

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• Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia.

  1992cited by this paper
• The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted alpha helices: crystal structure of the protein-DNA complex.

  1992influential reference
• Conservation and evolution of transcriptional mechanisms in eukaryotes.

  1992cited by this paper
• A tobacco bZip transcription activator (TAF‐1) binds to a G‐box‐like motif conserved in plant genes.

  1991cited by this paper
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  1991cited by this paper
• DNA-induced increase in the alpha-helical content of C/EBP and GCN4.

  1991cited by this paper
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  1991cited by this paper
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  1991cited by this paper
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  1991cited by this paper
• The leucine zipper symmetrically positions the adjacent basic regions for specific DNA binding.

  1991cited by this paper
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  1991cited by this paper
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  1991cited by this paper
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  1991cited by this paper
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  1990influential reference
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  1990cited by this paper
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  1990cited by this paper
• Defining Target Sequences of DNA-Binding Proteins by Random Selection and PCR: Determination of the GCN4 Binding Sequence Repertoire

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  1990cited by this paper
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  1990influential reference
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  1990cited by this paper
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  1990cited by this paper
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  1990cited by this paper
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  1990cited by this paper
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  1990cited by this paper
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  1990cited by this paper
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  1989cited by this paper
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  1989cited by this paper
• Leucine zippers of fos, jun and GCN4 dictate dimerization specificity and thereby control DNA binding

  1989cited by this paper
• Two tobacco DNA-binding proteins with homology to the nuclear factor CREB

  1989cited by this paper
• Two functionally different regions in Fos are required for the sequence-specific DNA interaction of the Fos/Jun protein complex

  1989cited by this paper
• Parallel association of Fos and Jun leucine zippers juxtaposes DNA binding domains.

  1989cited by this paper
• Yeast YAP1 encodes a novel form of the jun family of transcriptional activator proteins.

  1989cited by this paper
• Leucine repeats and an adjacent DNA binding domain mediate the formation of functional cFos-cJun heterodimers.

  1989cited by this paper
• The basic region of Fos mediates specific DNA binding.

  1989cited by this paper
• Precise gene fusion by PCR.

  1989cited by this paper
• Biochemical analysis of transcriptional activation by Jun: differential activity of c- and v-Jun.

  1989cited by this paper
• jun-D: a third member of the jun gene family.

  1989cited by this paper
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  1989cited by this paper
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  1989cited by this paper
• Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers.

  1989cited by this paper
• Evidence that the leucine zipper is a coiled coil.

  1989cited by this paper
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  1989cited by this paper
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  1989cited by this paper
• Defining the sequence specificity of DNA-binding proteins by selecting binding sites from random-sequence oligonucleotides: analysis of yeast GCN4 protein

  1989cited by this paper
• Cognate DNA binding specificity retained after leucine zipper exchange between GCN4 and C/EBP.

  1989cited by this paper
• Scissors-grip model for DNA recognition by a family of leucine zipper proteins.

  1989influential reference
• A gene activated by growth factors is related to the oncogene v-jun.

  1988cited by this paper
• Isolation of a recombinant copy of the gene encoding C/EBP.

  1988cited by this paper
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  1988cited by this paper
• The role of the leucine zipper in the fos–jun interaction

  1988cited by this paper
• Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain

  1988cited by this paper
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  1988cited by this paper
• Amino acid preferences for specific locations at the ends of alpha helices.

  1988cited by this paper
• fra-1: aSerum-Inducible, Cellular Immediate-Early GeneThat Encodes aFos-Related Antigen

  1988cited by this paper
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  1988cited by this paper
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  1988cited by this paper
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  1987cited by this paper
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  1987cited by this paper
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  1987cited by this paper
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  1987cited by this paper
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  1987cited by this paper
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  1987cited by this paper
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  1987cited by this paper
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  1985cited by this paper
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  1984cited by this paper
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  1984cited by this paper
• Protein-DNA recognition.

  1984cited by this paper
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  1984cited by this paper
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  1983cited by this paper
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  1983cited by this paper

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