Distal connectivity causes summation and division across mouse visual cortex

Neurons in different locations across the cortex are connected through polysynaptic networks involving both excitation and inhibition. To probe the functional effect of such networks, we used optogenetic stimulation to trigger antidromic spikes in a local region of primary visual cortex (V1). This local activity had two effects at distal V1 locations: summation and division. The balance between the two depended on visual contrast, and a normalization model precisely captured these effects.

• Publication year

  2013

• Venue

  Nature Neuroscience

• Publication date

  2013-11-17

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1038/nn.3585PMID 24241394PMCID 5953407
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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