Proton MRS reveals frontal lobe metabolite abnormalities in idiopathic generalized epilepsy

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Neurology

• Publication date

  2003-10-14

• Fields of study

  Medicine

• Identifiers
  DOI 10.1212/01.WNL.0000086903.69738.DCPMID 14557556
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A Proton Magnetic Resonance Spectroscopy Study of Metabolites in the Occipital Lobes in Epilepsy

  2003cited by this paper
• In vivo GABA+ measurement at 1.5T using a PRESS‐localized double quantum filter

  2002cited by this paper
• Valproate‐induced Encephalopathy: Assessment with MR Imaging and 1H MR Spectroscopy

  2002cited by this paper
• Modulation of cerebral GABA by topiramate, lamotrigine, and gabapentin in healthy adults

  2002cited by this paper
• A Short‐echo‐time Proton Magnetic Resonance Spectroscopic Imaging Study of Temporal Lobe Epilepsy

  2002cited by this paper
• Neuropsychological assessment in children with absence epilepsy

  2001cited by this paper
• Variability and asymmetry in the human precentral motor system. A cytoarchitectonic and myeloarchitectonic brain mapping study.

  2001cited by this paper
• Homocarnosine and seizure control in juvenile myoclonic epilepsy and complex partial seizures

  2001cited by this paper
• Homocarnosine elevations A cause or a sign of seizure control?

  2001cited by this paper
• Automatic quantitation of localized in vivo 1H spectra with LCModel

  2001cited by this paper
• Effects of Vigabatrin on Brain GABA+/CR Signals in Patients with Epilepsy Monitored by 1H‐NMR‐Spectroscopy: Responder Characteristics

  2001cited by this paper
• Structural asymmetries in the human brain: a voxel-based statistical analysis of 142 MRI scans.

  2001cited by this paper
• In Vivo Short Echo Time 1H-Magnetic Resonance Spectroscopic Imaging (MRSI) of the Temporal Lobes

  2001cited by this paper
• In vivo detection of postictal perturbations of cerebral metabolism by use of proton MR spectroscopy: preliminary results in a canine model of prolonged generalized seizures.

  2001cited by this paper
• Brain GABA editing without macromolecule contamination

  2001cited by this paper
• Depression and Anxiety in Patients with Epilepsy

  2001cited by this paper
• Proton MRS: GABA and glutamate.

  2000cited by this paper
• Quantitative analysis of short echo time 1H‐MRSI of cerebral gray and white matter

  2000cited by this paper
• The high affinity inositol transport system--implications for the pathophysiology and treatment of bipolar disorder.

  2000cited by this paper
• Fear recognition deficits after focal brain damage

  2000cited by this paper
• Chronic lithium and sodium valproate both decrease the concentration of myo-inositol and increase the concentration of inositol monophosphates in rat brain.

  2000cited by this paper
• MR Spectroscopy Shows Reduced Frontal Lobe Concentrations of N‐Acetyl Aspartate in Patients with Juvenile Myoclonic Epilepsy

  2000cited by this paper
• Short echo time single‐voxel 1H magnetic resonance spectroscopy in magnetic resonance imaging–negative temporal lobe epilepsy: Different biochemical profile compared with hippocampal sclerosis

  1999cited by this paper
• Acute Effects of Vigabatrin on Brain GABA and Homocarnosine in Patients with Complex Partial Seizures

  1999cited by this paper
• Abnormal cerebral structure in juvenile myoclonic epilepsy demonstrated with voxel-based analysis of MRI.

  1999cited by this paper
• Simultaneous in vivo spectral editing and water suppression

  1998cited by this paper
• GABA and Epileptogenesis

  1997cited by this paper
• Quantitative MRI in patients with idiopathic generalized epilepsy. Evidence of widespread cerebral structural changes.

  1997cited by this paper
• In vivo detection of GABA in human brain using a localized double‐quantum filter technique

  1997cited by this paper
• Low brain GABA level is associated with poor seizure control

  1996cited by this paper
• Asymmetry in the human motor cortex and handedness.

  1996cited by this paper
• Visual working memory in primary generalized epilepsy

  1996cited by this paper
• Primary (Idiopathic) Generalized Epilepsy and Underlying Mechanisms

  1996cited by this paper
• Symbiosis between in vivo and in vitro NMR spectroscopy: the creatine, N-acetylaspartate, glutamate, and GABA content of the epileptic human brain.

  1995cited by this paper
• Compartmentation of cerebral glutamate in situ as detected by 1H/13C n.m.r.

  1994cited by this paper
• 1H Magnetic resonance spectroscopy of extracts of human epileptic neocortex and hippocampus

  1993cited by this paper
• Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain.

  1993cited by this paper
• Nuclear magnetic resonance study of cerebrospinal fluid from patients with multiple sclerosis.

  1993cited by this paper
• Excitatory Amino Acids Modulate Phosphoinositide Signal Transduction in Human Epileptic Neocortex

  1992cited by this paper
• Excitatory amino acids are elevated in human epileptic cerebral cortex

  1988cited by this paper

• Glutamate to GABA ratio is elevated in patients with IDH-mutant lower-grade gliomas and seizures

  2025cites this paper
• Denoising magnetic resonance spectroscopy (MRS) data using stacked autoencoder for improving signal-to-noise ratio and speed of MRS.

  2023cites this paper
• Denoising Magnetic Resonance Spectroscopy (MRS) Data Using Stacked Autoencoder for Improving Signal-to-Noise Ratio and Speed of MRS.

  2023cites this paper
• γ-Aminobutyric acid as a biomarker of the lateralizing and monitoring drug effect in patients with magnetic resonance imaging-negative temporal lobe epilepsy

  2023influential citation
• Neurophysiology of Juvenile and Progressive Myoclonic Epilepsy

  2022cites this paper
• Cambios estructurales cerebrales en la epilepsia mioclónica juvenil farmacorresistente

  2022cites this paper
• Glutamic acid and total creatine as predictive markers for epilepsy in glioblastoma by using magnetic resonance spectroscopy prior to surgery.

  2022cites this paper
• Quantitative 1H-MRS reveals metabolic difference between subcategories of malformations of cortical development

  2021cites this paper
• Metabolic alterations of the dorsolateral prefrontal cortex in sleep‐related hypermotor epilepsy: A proton magnetic resonance spectroscopy study

  2021cites this paper
• A systematic review of resting-state and task-based fmri in juvenile myoclonic epilepsy

  2021cites this paper
• Investigation of Patients With Eye Closure Sensitive Epilepsy With Magnetic Resonance Spectroscopy

  2021cites this paper
• Executive functions and personality traits of juvenile myoclonic epilepsy patients: a single-center experience of 23 cases

  2021cites this paper
• Structural and Functional Brain Abnormalities in Mouse Models of Lafora Disease

  2020cites this paper
• Neurochemicals of limbic system and thalamofrontal cortical network: Are they different between patients with idiopathic generalized epilepsy and psychogenic nonepileptic seizure?

  2020cites this paper
• Seven‐tesla quantitative magnetic resonance spectroscopy of glutamate, γ‐aminobutyric acid, and glutathione in the posterior cingulate cortex/precuneus in patients with epilepsy

  2020cites this paper
• In Vivo Imaging of Neuroinflammatory Targets in Treatment-Resistant Epilepsy

  2020cites this paper
• The Use of Proton MR Spectroscopy in Epilepsy: A Methodological Review

  2019cites this paper
• Subtle Brain Developmental Abnormalities in the Pathogenesis of Juvenile Myoclonic Epilepsy

  2019cites this paper
• Attention and inhibitory control deficits in patients with genetic generalized epilepsy and psychogenic nonepileptic seizure.

  2019cites this paper
• Macromolecule-suppressed GABA measurements correlate more strongly with behavior than macromolecule-contaminated GABA+ measurements.

  2018cites this paper
• Altered Structural and Functional Connectivity of Juvenile Myoclonic Epilepsy: An fMRI Study

  2018cites this paper
• Two-Dimensional Proton Magnetic Resonance Spectroscopy versus J-Editing for GABA Quantification in Human Brain: Insights from a GABA-Aminotransferase Inhibitor Study

  2018cites this paper
• Towards a theory of functional magnetic resonance spectroscopy (fMRS): A meta-analysis and discussion of using MRS to measure changes in neurotransmitters in real time.

  2018cites this paper
• In Vivo Multimodal Magnetic Resonance Imaging Changes After N-Methyl-d-Aspartate-Triggered Spasms in Infant Rats

  2018cites this paper
• The effect of neurobiological changes in the brain of children with schizophrenia, ultra high-risk for psychosis and epilepsy: clinical correlations with EEG and neuroimagistic abnormalities.

  2017cites this paper
• Imaging Biomarkers of Anti-Epileptic Drug Action: Insights from Magnetic Resonance Imaging.

  2017cites this paper
• Juvenile myoclonic epilepsy may be a disorder of cortex rather than thalamus: An effective connectivity analysis.

  2017cites this paper
• Diagnostic Value of magnetic resonance spectroscopy in Morphometrical Analysis of basal ganglia in patients with Idiopathic Generalized Epilepsy

  2017cites this paper
• Grey and White Matter Alterations in Juvenile Myoclonic Epilepsy: A Comprehensive Review

  2017cites this paper
• Evaluation of cognitive functions of juvenile myoclonic epileptic patients by magnetic resonance spectroscopy and neuropsychiatric cognitive tests concurrently

  2016cites this paper
• Investigation of Magnetic Resonance Spectroscopy Findings in Patients with Absence Status Epilepticus

  2016influential citation
• Longitudinal metabolic changes in the thalamus of macaque brain during 42-day head down tilt.

  2016cites this paper
• Focal interictal epileptiform discharges in idiopathic generalized epilepsy

  2016cites this paper
• Neuroimaging of functional and structural alterations in Juvenile Myoclonic Epilepsy and Frontal Lobe Epilepsy

  2016cites this paper
• What graph theory actually tells us about resting state interictal MEG epileptic activity

  2015influential citation
• Types of Epilepsies and Findings EEG- LORETA about Epilepsy

  2015cites this paper
• Contributions of GABA to alcohol responsivity during adolescence: Insights from preclinical and clinical studies

  2015cites this paper
• Metabolic and functional MR biomarkers of antiepileptic drug effectiveness: A review.

  2015cites this paper
• Investigation of glutamine and GABA levels in patients with idiopathic generalized epilepsy using MEGAPRESS

  2015influential citation
• Proton magnetic resonance spectroscopy in epilepsy: key findings

  2015cites this paper
• Autoantibodies in CNS Trauma and Neuropsychiatric Disorders: A New Generation of Biomarkers

  2015cites this paper
• Functional magnetic resonance spectroscopic imaging of the mouse brain: overcoming current sensitivity limitations

  2015cites this paper
• Reprint of "Structural and functional correlates of epileptogenesis--does gender matter?".

  2014cites this paper
• Altered thalamocortical functional connectivity in idiopathic generalized epilepsy

  2014cites this paper
• Sex differences in human epilepsy.

  2014cites this paper
• Gannet: A batch‐processing tool for the quantitative analysis of gamma‐aminobutyric acid–edited MR spectroscopy spectra

  2014cites this paper
• Juvenile Myoclonic Epilepsy — A Maturation Syndrome Coming of Age

  2014cites this paper
• Structural and functional correlates of epileptogenesis - does gender matter?

  2014cites this paper
• Juvenile Myoclonic Epilepsy: An Update

  2014influential citation
• Focal abnormalities in idiopathic generalized epilepsy: A critical review of the literature

  2014cites this paper
• Title Structural-functional coupling changes in temporal lobe epilepsy

  2014cites this paper
• Effects of normal aging and SCN1A risk‐gene expression on brain metabolites: evidence for an association between SCN1A and myo‐inositol

  2014cites this paper
• GABAergic contributions to alcohol responsivity during adolescence: insights from preclinical and clinical studies.

  2014cites this paper
• Frontal and thalamic changes of GABA concentration indicate dysfunction of thalamofrontal networks in juvenile myoclonic epilepsy

  2014cites this paper
• Personality traits in juvenile myoclonic epilepsy: evidence of cortical abnormalities from a surface morphometry study.

  2013cites this paper
• GABA-Based Evaluation of Neurologic Conditions: MR Spectroscopy

  2013cites this paper
• Volumetric and shape analysis of thalamus in idiopathic generalized epilepsy

  2013cites this paper
• Juvenile myoclonic epilepsy--neuroimaging findings.

  2013cites this paper
• GABA-Based Evaluation of Neurologic Conditions:

  2013cites this paper
• Hippocampal atrophy and memory dysfunction in patients with juvenile myoclonic epilepsy.

  2013cites this paper
• Increased ratio of glutamate/glutamine to creatine in the right hippocampus contributes to depressive symptoms in patients with epilepsy.

  2013cites this paper
• Studio neuroradiologico (morfologico e funzionale) nei pazienti con Epilessia Frontale Notturna

  2013cites this paper
• Resting-State Functional Connectivity in Treatment-Resistant Idiopathic Generalized Epilepsy

  2013cites this paper
• Unedited in vivo detection and quantification of γ‐aminobutyric acid in the occipital cortex using short‐TE MRS at 3 T

  2013cites this paper
• In vivo magnetic resonance spectroscopy of GABA: a methodological review.

  2012cites this paper
• Bildgebung bei idiopathisch generalisierten Epilepsien

  2012cites this paper
• Magnetic Resonance Spectroscopy as applied to epilepsy

  2012cites this paper
• Microstructural white matter abnormality and frontal cognitive dysfunctions in juvenile myoclonic epilepsy

  2012cites this paper
• Proton MR Spectroscopy–Detectable Major Neurotransmitters of the Brain: Biology and Possible Clinical Applications

  2012cites this paper
• Focal structural changes and cognitive dysfunction in juvenile myoclonic epilepsy

  2011cites this paper
• The evaluation of treatment-resistant epilepsy.

  2011cites this paper
• Structural abnormalities of the thalamus in juvenile myoclonic epilepsy.

  2011cites this paper
• 1H MRSI and social communication deficits in pediatric complex partial seizures

  2011cites this paper
• Extracellular Glutamate, Glutamine, and GABA in the Hippocampus and Cortex of Refractory Epilepsy Patients

  2010cites this paper
• The dopamine system in idiopathic generalized epilepsies: Identification of syndrome-related changes

  2010cites this paper
• Attention networks in children with idiopathic generalized epilepsy.

  2010cites this paper
• Evidence that juvenile myoclonic epilepsy is a disorder of frontotemporal corticothalamic networks

  2010cites this paper
• Multi-voxel magnetic resonance spectroscopy at 3 T in patients with idiopathic generalised epilepsy.

  2010cites this paper
• Update on neuroimaging in epilepsy

  2010cites this paper
• Magnetic Resonance Spectroscopy Findings in Photosensitive Idiopathic Generalized Epilepsy

  2010cites this paper
• The integrity of corpus callosum and cluster B personality disorders: a quantitative MRI study in juvenile myoclonic epilepsy.

  2010cites this paper
• Correlation between quantitative EEG and MRI in idiopathic generalized epilepsy

  2010cites this paper
• Current themes in neuroimaging of epilepsy: brain networks, dynamic phenomena, and clinical relevance.

  2010cites this paper
• Proton MR spectroscopy of metabolite concentrations in temporal lobe epilepsy and effect of temporal lobe resection.

  2009influential citation
• Personality traits related to juvenile myoclonic epilepsy: MRI reveals prefrontal abnormalities through a voxel-based morphometry study.

  2009influential citation
• Thalamo-cortical network pathology in idiopathic generalized epilepsy: Insights from MRI-based morphometric correlation analysis

  2009cites this paper
• 1H‐MR spectroscopy indicates prominent cerebellar dysfunction in benign adult familial myoclonic epilepsy

  2009cites this paper
• Proton MR Spectroscopy Correlates of Frontal Lobe Function in Healthy Children

  2009cites this paper
• Estudo anátomo-funcional por ressonância magnética em pacientes com epilepsia mioclônica juvenil

  2009influential citation
• Are personality traits of juvenile myoclonic epilepsy related to frontal lobe dysfunctions? A proton MRS study

  2009influential citation
• Magnetic resonance spectroscopy reveals an epileptic network in juvenile myoclonic epilepsy

  2009influential citation
• Voxel-based morphometry evaluation of patients with photosensitive juvenile myoclonic epilepsy.

  2009cites this paper
• Lithium and valproate and their possible effects on themyo-inositol second messenger system in healthy volunteers and bipolar patients

  2009cites this paper
• Frontal cognitive dysfunction in juvenile myoclonic epilepsy

  2008cites this paper
• Metabolic changes in temporal lobe structures measured by HR-MAS NMR at early stage of electrogenic rat epilepsy.

  2008cites this paper
• The effect of epileptic seizures on proton MRS visible neurochemical concentrations.

  2008cites this paper
• The effect of sodium valproate on proton MRS visible neurochemical concentrations.

  2007cites this paper
• Spectroscopie par résonance magnétique du proton. Quelles indications neurologiques en 2007

  2007cites this paper
• Magnetic Resonance Spectroscopy of Thalamus in Idiopathic Generalized and Focal Epilepsies

  2007cites this paper
• BRAIN IMAGING STUDIES OF HUMAN EPILEPSY

  2007cites this paper