Clinical deterioration in probable Alzheimer's disease correlates with progressive metabolic impairment of association areas.

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Dementia

• Publication date

  1994-01-12

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1159/000106692PMID 8156085
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Alzheimer's disease affects limbic nuclei of the thalamus

  2004cited by this paper
• Differences of regional cerebral glucose metabolism between presenile and senile dementia of Alzheimer type.

  1992cited by this paper
• Predictors of decline in Alzheimer's disease.

  1991cited by this paper
• High-resolution PET studies in Alzheimer's disease.

  1991cited by this paper
• Nerve cell loss in the thalamus in Alzheimer's disease and Parkinson's disease.

  1991cited by this paper
• Progression of Cognitive Impairment in Alzheimer's Disease

  1991cited by this paper
• Longitudinal study of cerebral metabolic asymmetries and associated neuropsychological patterns in early dementia of the Alzheimer type.

  1990cited by this paper
• Longitudinal evaluation of dementia of the Alzheimer type

  1990cited by this paper
• Alzheimer's disease with prominent visual symptoms. Clinical and metabolic evaluation.

  1989cited by this paper
• Crossed cerebellar and uncrossed basal ganglia and thalarnic diaschisis in Alzheimer's disease

  1989cited by this paper
• Longitudinal study of the early neuropsychological and cerebral metabolic changes in dementia of the Alzheimer type.

  1988cited by this paper
• Validation of clinical diagnostic criteria for Alzheimer's disease

  1988cited by this paper
• Longitudinal studies of regional cerebral metabolism in Alzheimer's disease

  1988cited by this paper
• Alzheimer's disease: Neurofibrillary tangles in nuclei that project to the cerebral cortex

  1987cited by this paper
• Age at Onset and Rate of Progression of Alzheimer's Disease

  1987cited by this paper
• A longitudinal, behavioral study of senile dementia of the Alzheimer type.

  1986cited by this paper
• Stability of metabolic and neuropsychological asymmetries in dementia of the Alzheimer type

  1986cited by this paper
• Positron emission tomography in Alzheimer's disease

  1986cited by this paper
• Positron emission tomography in patients with clinically diagnosed Alzheimer's disease.

  1986cited by this paper
• Subcortical degeneration in Alzheimer's disease

  1985cited by this paper
• Computer Assisted Mapping in Quantitative Analysis of Cerebral Positron Emission Tomograms

  1985cited by this paper
• Estimation of Local Cerebral Glucose Utilization by Positron Emission Tomography of [18F]2-Fluoro-2-Deoxy-D-Glucose: A Critical Appraisal of Optimization Procedures

  1985cited by this paper
• Clinical diagnosis of Alzheimer's disease

  1984cited by this paper
• Alzheimer's disease and the parietal lobe.

  1983cited by this paper
• Regional Cerebral Metabolic Alterations in Dementia of the Alzheimer Type: Positron Emission Tomography with [1818] Fluorodeoxyglucose

  1983cited by this paper
• The fluorodeoxyglucose 18F scan in Alzheimer's disease and multi-infarct dementia.

  1983cited by this paper
• Alzheimer's disease

  1983cited by this paper
• Pathological verification of ischemic score in differentiation of dementias

  1980cited by this paper
• The [18F]Fluorodeoxyglucose Method for the Measurement of Local Cerebral Glucose Utilization in Mane

  1979cited by this paper

• Electro-Calcium uncoupling precedes neurodegeneration in Alzheimer’s disease

  2026cites this paper
• Liver X receptor alpha ensures blood-brain barrier function by suppressing SNAI2

  2023cites this paper
• Experimental Approach to Alzheimer’s Disease with Emphasis on Insulin Resistance in the Brain

  2021cites this paper
• Frontal Cortex Segmentation of Brain PET Imaging Using Deep Neural Networks

  2021cites this paper
• Modifiable, Non-Modifiable, and Clinical Factors Associated with Progression of Alzheimer’s Disease

  2021cites this paper
• Cerebral blood flow decrease as an early pathological mechanism in Alzheimer's disease

  2020cites this paper
• Molecular and Imaging Biomarkers in Alzheimer’s Disease: A Focus on Recent Insights

  2020cites this paper
• Prognostic value of complementary biomarkers of neurodegeneration in a mixed memory clinic cohort

  2020cites this paper
• Computational identification of key genes that may regulate gene expression reprogramming in Alzheimer’s patients

  2019cites this paper
• Calpain I Activation Causes GLUT3 Proteolysis and Downregulation of O-GlcNAcylation in Alzheimer’s Disease Brain

  2018cites this paper
• ACCELERATED EVALUATION OF TREATMENTS TO PREVENT CLINICAL ONSET OF ALZHEMERS DISEASE

  2017cites this paper
• Differential Effect of APOE Alleles on Brain Glucose Metabolism in Targeted Replacement Mice: An [18F]FDG-μPET Study

  2017cites this paper
• An 8-week open label trial of l-Threonic Acid Magnesium Salt in patients with mild to moderate dementia

  2017cites this paper
• Imaging Biomarkers in Alzheimer’s Disease: A Practical Guide for Clinicians

  2017cites this paper
• Human ApoE ɛ2 Promotes Regulatory Mechanisms of Bioenergetic and Synaptic Function in Female Brain: A Focus on V-type H+-ATPase

  2016cites this paper
• brain human functionally distinct regions of the normal aged Gene expression profiles in anatomically and

  2015cites this paper
• Brain aerobic glycolysis functions and Alzheimer’s disease

  2015cites this paper
• O-GlcNAc and neurodegeneration: biochemical mechanisms and potential roles in Alzheimer's disease and beyond.

  2014cites this paper
• Gene Expression Profiles of Entorhinal Cortex in Alzheimer’s Disease

  2014influential citation
• Positron Emission Tomography

  2013cites this paper
• Experimental approach to Alzheimer's disease

  2013cites this paper
• Neural correlates of the DemTect in Alzheimer's disease and frontotemporal lobar degeneration – A combined MRI & FDG-PET study

  2013cites this paper
• Development of functional tools to study the role of O-GlcNAc in tau biology

  2013cites this paper
• O-GlcNAc cycling: a link between metabolism and chronic disease.

  2013cites this paper
• Cognition, glucose metabolism and amyloid burden in Alzheimer's disease.

  2012influential citation
• Use of FDG PET as an imaging biomarker in clinical trials of Alzheimer's disease.

  2012cites this paper
• Glucose administration attenuates spatial memory deficits induced by chronic low-power-density microwave exposure.

  2012cites this paper
• Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation.

  2012cites this paper
• Unveiling Molecular Events in the Brain by Noninvasive Imaging

  2011cites this paper
• Molecular Imaging in Alzheimer ’ s Disease

  2011cites this paper
• Lectin‐affinity chromatography brain glycoproteomics and Alzheimer disease: Insights into protein alterations consistent with the pathology and progression of this dementing disorder

  2011cites this paper
• PET/CT in diagnosis of dementia

  2011cites this paper
• Perfusion SPECT and FDG-PET

  2011cites this paper
• Spatial correlation between brain aerobic glycolysis and amyloid-β (Aβ) deposition

  2010cites this paper
• Neuronal gene expression in non-demented individuals with intermediate Alzheimer's Disease neuropathology.

  2010cites this paper
• Regional cerebral glucose uptake in the 3xTG model of Alzheimer's disease highlights common regional vulnerability across AD mouse models.

  2010cites this paper
• Twelve-month metabolic declines in probable Alzheimer's disease and amnestic mild cognitive impairment assessed using an empirically pre-defined statistical region-of-interest: Findings from the Alzheimer's Disease Neuroimaging Initiative

  2010cites this paper
• Brain SPECT Findings of Anosognosia in Alzheimer's Disease

  2010cites this paper
• PL‐05‐03: Metabolic and molecular imaging markers throughout the course of Alzheimer's disease

  2010cites this paper
• Modeling Sporadic Alzheimer's Disease: The Insulin Resistant Brain State Generates Multiple Long-Term Morphobiological Abnormalities Including Hyperphosphorylated Tau Protein and Amyloid-β

  2009cites this paper
• Regional cerebral glucose metabolism and postmortem pathology in Alzheimer’s disease

  2009cites this paper
• Association between FDG uptake, CSF biomarkers and cognitive performance in patients with probable Alzheimer’s disease

  2009cites this paper
• Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease.

  2009cites this paper
• Fluoro-2-deoxy-D-glucose (FDG)-PET in APOEepsilon4 carriers in the Australian population.

  2008cites this paper
• Functional neuroimaging of cognition.

  2008cites this paper
• Imaging of Dementia

  2008cites this paper
• Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set.

  2008cites this paper
• Fluoro-2-Deoxy-D-Glucose (FDG)-PET in APOEε4 Carriers in the Australian Population

  2008cites this paper
• Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons

  2008cites this paper
• Inherited and Acquired Disorders of Platelet Function

  2007cites this paper
• Quantitative Cytochrome Oxidase Histochemistry: Applications in Human Alzheimer's Disease and Animal Models

  2007cites this paper
• Dementia: The Significance of Cerebral Metabolic Disturbances in Alzheimer's Disease. Relation to Parkinson's Disease

  2007cites this paper
• Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain.

  2007cites this paper
• Beyond symptomatic therapy: a re-examination of acetylcholinesterase inhibitors in Alzheimer’s disease

  2007cites this paper
• Gene expression profiles of metabolic enzyme transcripts in Alzheimer's disease.

  2007cites this paper
• Alzheimer Disease—No Target for Statin Treatment. A Mini Review

  2007cites this paper
• Long-term abnormalities in brain glucose/energy metabolism after inhibition of the neuronal insulin receptor: implication of tau-protein.

  2007cites this paper
• Positron emission tomography imaging in dementia.

  2007cites this paper
• Reduced functional brain activity response in cognitively intact apolipoprotein E ε4 carriers

  2006cites this paper
• Alois Alzheimer revisited: differences in origin of the disease carrying his name

  2006cites this paper
• Propyl gallate‐induced platelet aggregation in patients with end‐stage renal disease: The influence of the haemodialysis procedure

  2006cites this paper
• Elevated fibrinogen fragment levels in uremic plasma inhibit platelet function and expression of glycoprotein IIb‐IIIa

  2006cites this paper
• Effects of Nafamostat Mesilate on ADP-Induced Platelet Aggregation and Disaggregation in Hemodialysis Patients

  2006cites this paper
• Reduced functional brain activity response in cognitively intact apolipoprotein E epsilon4 carriers.

  2006cites this paper
• What Constitutes Clinical Evidence for Neuroprotection in Alzheimer Disease: Support for the Cholinesterase Inhibitors?

  2006cites this paper
• Age- and transgene-related changes in regional cerebral metabolism in PSAPP mice.

  2006cites this paper
• Vascular determinants of cholinergic deficits in Alzheimer disease and vascular dementia.

  2006cites this paper
• Impaired platelet mitochondrial activity in Alzheimer's disease and mild cognitive impairment.

  2006cites this paper
• Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications

  2005cites this paper
• [Functional disorders of FOF1-ATPase in submitochondrial particles obtained from platelets of patients with a diagnosis of probable Alzheimer's disease].

  2005cites this paper
• Functional studies of cholinergic activity in normal and Alzheimer disease states by imaging technique.

  2004cites this paper
• The Living Brain and Alzheimer’s Disease

  2004cites this paper
• Positron Emission Tomography and Magnetic Resonance Imaging in the Study of Cognitively Normal Persons at Differential Genetic Risk for Alzheimer’s Dementia

  2004cites this paper
• Quantitative EEG and dynamic susceptibility contrast MRI in Alzheimer's disease: a correlative study.

  2003cites this paper
• Imaging Alzheimer's disease: clinical applications.

  2003cites this paper
• Reactivation of atrophic neurons in Alzheimer's disease

  2003cites this paper
• Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia

  2003cites this paper
• Donepezil HCl (E2020) maintains functional brain activity in patients with Alzheimer disease: results of a 24-week, double-blind, placebo-controlled study.

  2003cites this paper
• [PET and SPECT investigations in Alzheimer's disease].

  2003cites this paper
• Imaging-based measures of disease progression in clinical trials of disease-modifying drugs for Alzheimer disease.

  2003cites this paper
• Nuklearmedizin und Demenz—Anwendung bei Morbus Alzheimer

  2003cites this paper
• Functional Activation Studies in Alzheimer Patients and Strategies in Drug Evaluation

  2002cites this paper
• Effects of Image Resolution on Autoradiographic Measurements of Posterior Cingulate Activity in PDAPP Mice: Implications for Functional Brain Imaging Studies of Transgenic Mouse Models of Alzheimer's Disease

  2002cites this paper
• Brain Glucose Hypometabolism after Perirhinal Lesions in Baboons: Implications for Alzheimer Disease and Aging

  2002cites this paper
• Brain aging and Alzheimer's disease; use it or lose it.

  2002cites this paper
• Use of Positron Emission Tomography and Other Neuroimaging Techniques in the Diagnosis and Management of Alzheimer’s Disease and Dementia

  2001cites this paper
• Martin Sarter query " Could we train individuals to activate appropriate brain regions and thereby enhance their abilities ?

  2001cites this paper
• Preclinical cognitive decline in late middle-aged asymptomatic apolipoprotein E-e4/4 homozygotes: a replication study.

  2001cites this paper
• Clinical Aspects of Alzheimer’s Disease

  2001cites this paper
• Effect of Mitochondrial Electron Transport Chain Inhibitors on Superoxide Radical Generation in Rat Hippocampal and Striatal Slices

  2001cites this paper
• Diffusion and perfusion MR imaging in cases of Alzheimer's disease: correlations with cortical atrophy and lesion load.

  2001cites this paper
• Mitochondrial dysfunction in neurodegenerative disorders and ageing.

  2001cites this paper
• Patterns of cortical activity and memory performance in Alzheimer's disease.

  2001cites this paper
• Positronen-Emissions-Tomographie (PET)

  2001cites this paper
• Statistical maps of cerebral blood flow deficits in Alzheimer’s disease

  2000cites this paper
• Discrimination of Alzheimer's disease and mild cognitive impairment by equivalent EEG sources: a cross-sectional and longitudinal study.

  2000cites this paper
• Early Diagnosis of Alzheimer Disease With Positron Emission Tomography

  2000cites this paper
• PRECLINICAL EVIDENCE OF ALZHEIMER’S DISEASE IN PERSONS HOMOZYGOUS FOR THE

  2000cites this paper
• Abnormal platelet cytoskeletal assembly in hemodialyzed patients results in deficient tyrosine phosphorylation signaling.

  2000cites this paper
• Severe degenerative cortical and cerebellar atrophy and progressive dementia in a young adult

  2000cites this paper