SLAC, a complex between Sla1 and Las17, regulates actin polymerization during clathrin-mediated endocytosis

During endocytosis, actin polymerization nucleated by the Arp2/3 complex provides force needed to drive internalization. Las17 is the strongest activator of the Arp2/3 complex in yeast cells. This study shows that Las17 is associated into a stable complex with Sla1, an adaptor that inhibits Las17 activity both in vitro and in vivo.

• Publication year

  2012

• Venue

  Molecular Biology of the Cell

• Publication date

  2012-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1091/mbc.E11-12-1022PMID 22973053PMCID 3484103
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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