Development of Heart Failure in Chronic Hypertensive Dahl Rats: Focus on Heart Failure With Preserved Ejection Fraction

No abstract is available for this paper.

• Publication year

  2006

• Venue

  HYPERTENSION

• Publication date

  2006-05-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1161/01.HYP.0000215579.81408.8ePMID 16585423
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Exercise intolerance.

  2008cited by this paper
• Ventricular volume and length in hypertensive diastolic heart failure.

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• Ventricular Structure and Function in Aged Dogs With Renal Hypertension: A Model of Experimental Diastolic Heart Failure

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• Diastolic heart failure--abnormalities in active relaxation and passive stiffness of the left ventricle.

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• Hospitalization for heart failure in the presence of a normal left ventricular ejection fraction: results of the New York Heart Failure Registry.

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• Congestive heart failure in the elderly: the Cardiovascular Health Study.

  2004cited by this paper
• Increased left ventricular mass is a risk factor for the development of a depressed left ventricular ejection fraction within five years: the Cardiovascular Health Study.

  2004cited by this paper
• Diastolic heart failure.

  2004cited by this paper
• Lack of relationship between Doppler indices of diastolic function and left ventricular pressure transients in patients with definite diastolic heart failure.

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• Impaired Ca2+ handling in perfused hypertrophic hearts from Dahl salt-sensitive rats.

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  2000cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1997cited by this paper
• Impact of exercise training on ventricular properties in a canine model of congestive heart failure.

  1997cited by this paper
• Left ventricular volumetric conductance catheter for rats.

  1996cited by this paper
• Two-dimensional echocardiographic calculation of left ventricular mass as recommended by the American Society of Echocardiography: correlation with autopsy and M-mode echocardiography.

  1996cited by this paper
• Gender differences in older patients with pressure-overload hypertrophy of the left ventricle.

  1995cited by this paper
• Serial echocardiographic-Doppler assessment of left ventricular geometry and function in rats with pressure-overload hypertrophy. Chronic angiotensin-converting enzyme inhibition attenuates the transition to heart failure.

  1995cited by this paper
• Assessment of left ventricular function by the midwall fractional shortening/end-systolic stress relation in human hypertension.

  1994cited by this paper
• Characterization of new inbred strains of Dahl-Iwai salt-sensitive and salt-resistant rats.

  1994cited by this paper
• Why does pulmonary venous pressure rise after onset of LV dysfunction: a theoretical analysis.

  1993cited by this paper
• Ultrasound beam orientation during standard two-dimensional imaging: assessment by three-dimensional echocardiography.

  1992cited by this paper
• Salt and Hypertension Lessons From Animal Models That Relate to Human Hypertension

  1991cited by this paper
• Left ventricular diastolic dysfunction limits use of maximum systolic elastance as an index of contractile function.

  1991cited by this paper
• Clinical assessment of diastolic function.

  1990cited by this paper
• Left ventricular chamber filling and midwall fiber lengthening in patients with left ventricular hypertrophy: overestimation of fiber velocities by conventional midwall measurements.

  1985cited by this paper
• Echocardiographic Determination of Left Ventricular Mass in Man: Anatomic Validation of the Method

  1977cited by this paper
• Hemodynamic determinants of the time-course of fall in canine left ventricular pressure.

  1976cited by this paper
• Salt and hypertension.

  1972cited by this paper

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