Computational analysis of microRNA profiles and their target genes suggests significant involvement in breast cancer antiestrogen resistance

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Bioinform.

• Publication date

  2009-02-01

• Fields of study

  Biology, Medicine, Computer Science

• Identifiers
  DOI 10.1093/bioinformatics/btn646PMID 19091772PMCID PMC2642642
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• miR‐15b and miR‐16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells

  2008cited by this paper
• MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN (Cancer Research (2008) 68, (425-433))

  2008cited by this paper
• Widespread changes in protein synthesis induced by microRNAs

  2008cited by this paper
• The impact of microRNAs on protein output

  2008cited by this paper
• MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN.

  2008cited by this paper
• miR2Disease: a manually curated database for microRNA deregulation in human disease

  2008cited by this paper
• An Integrated Approach to the Prediction of Chemotherapeutic Response in Patients with Breast Cancer

  2008cited by this paper
• Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer

  2008cited by this paper
• MicroRNAs modulate the chemosensitivity of tumor cells

  2008cited by this paper
• Genome analysis of the platypus reveals unique signatures of evolution

  2008cited by this paper
• Epigenetic gene silencing in the Wnt pathway in breast cancer

  2008cited by this paper
• The role of site accessibility in microRNA target recognition

  2007cited by this paper
• MicroRNAs in human cancer: from research to therapy

  2007cited by this paper
• microRNAs and cancer: role in tumorigenesis, patient classification and therapy

  2007cited by this paper
• Tumour invasion and metastasis initiated by microRNA-10b in breast cancer

  2007cited by this paper
• A systems biology approach for pathway level analysis.

  2007cited by this paper
• MicroRNA-cancer connection: the beginning of a new tale.

  2006cited by this paper
• Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant.

  2006cited by this paper
• Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines.

  2006cited by this paper
• Fulvestrant (ICI 182,780)-dependent Interacting Proteins Mediate Immobilization and Degradation of Estrogen Receptor-α*

  2006cited by this paper
• A microRNA expression signature of human solid tumors defines cancer gene targets

  2006cited by this paper
• RAS is regulated by the let-7 microRNA family.

  2005cited by this paper
• A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation.

  2005cited by this paper
• Dual role of transforming growth factor beta in mammary tumorigenesis and metastatic progression.

  2005cited by this paper
• The Widespread Impact of Mammalian MicroRNAs on mRNA Repression and Evolution

  2005cited by this paper
• The molecular pharmacology of estrogen receptor modulators: implications for the treatment of breast cancer.

  2005cited by this paper
• MicroRNA expression profiles classify human cancers

  2005cited by this paper
• Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

  2005cited by this paper
• MicroRNA gene expression deregulation in human breast cancer.

  2005cited by this paper
• Accumulation of miR-155 and BIC RNA in human B cell lymphomas.

  2005cited by this paper
• Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation.

  2005cited by this paper
• Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets.

  2005cited by this paper
• Clinical development of fulvestrant ("Faslodex").

  2005cited by this paper
• miR-15 and miR-16 induce apoptosis by targeting BCL2.

  2005cited by this paper
• Role of transforming growth factor beta in breast carcinogenesis.

  2004cited by this paper
• A custom microarray platform for analysis of microRNA gene expression

  2004cited by this paper
• Role of transforming growth factor in breast carcinogenesis

  2004cited by this paper
• Reduced Expression of the let-7 MicroRNAs in Human Lung Cancers in Association with Shortened Postoperative Survival

  2004cited by this paper
• Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells

  2003cited by this paper
• The NEDD8 pathway is required for proteasome-mediated degradation of human estrogen receptor (ER)-alpha and essential for the antiproliferative activity of ICI 182,780 in ERalpha-positive breast cancer cells.

  2003cited by this paper
• Future use of selective estrogen receptor modulators and aromatase inhibitors.

  2001cited by this paper
• β-Catenin, a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression

  2000cited by this paper
• Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression.

  2000cited by this paper
• Faslodex (ICI 182780). an oestrogen receptor downregulator.

  2000cited by this paper
• Cluster analysis and display of genome-wide expression patterns.

  1998cited by this paper

• A DNA nanowire based-DNAzyme walker for amplified imaging of microRNA in tumor cells.

  2024cites this paper
• MicroRNA-143 as a potential tumor suppressor in cancer: An insight into molecular targets and signaling pathways.

  2023cites this paper
• MiR-590-5p promotes cisplatin resistance via targeting hMSH2 in ovarian cancer

  2023cites this paper
• MicroRNAs as Molecular Biomarkers for the Characterization of Basal-like Breast Tumor Subtype

  2023cites this paper
• MicroRNAs and drug resistance in colorectal cancer with special focus on 5-fluorouracil

  2022cites this paper
• Genosensors, a nanomaterial-based platform for microRNA-21 detection, non-invasive methods in early detection of cancer.

  2022cites this paper
• A Survey on Computational Methods for Investigation on ncRNA-Disease Association through the Mode of Action Perspective

  2022cites this paper
• MicroRNA as a Potential Therapeutic Molecule in Cancer

  2022cites this paper
• Strategies for Improving Photodynamic Therapy Through Pharmacological Modulation of the Immediate Early Stress Response.

  2022cites this paper
• Molecular Mechanisms of Anti-Estrogen Therapy Resistance and Novel Targeted Therapies

  2022cites this paper
• Predicting drug-resistant miRNAs in cancer

  2022cites this paper
• The effects of estrogen on targeted cancer therapy drugs.

  2022cites this paper
• Crosstalk between non-coding RNAs expression profile, drug resistance and immune response in breast cancer.

  2021cites this paper
• Effects of miR-125b-5p on Preadipocyte Proliferation and Differentiation in Chicken

  2021cites this paper
• miRNA Expression Profiles in Luminal A Breast Cancer—Implications in Biology, Prognosis, and Prediction of Response to Hormonal Treatment

  2020cites this paper
• The Emerging Role of MicroRNAs in Breast Cancer

  2020cites this paper
• Exosome as a Natural Gene Delivery Vector for Cancer Treatment.

  2020cites this paper
• MicroRNAs in breast cancer: New maestros defining the melody.

  2020cites this paper
• Machine learning-based analysis of multi-omics data on the cloud for investigating gene regulations

  2020cites this paper
• Regulation of breast cancer metastasis signaling by miRNAs

  2020cites this paper
• Identification of potential plasma biomarkers in early-stage nasopharyngeal carcinoma-derived exosomes based on RNA sequencing

  2020cites this paper
• Transcriptome Characterization of Repressed Embryonic Myogenesis Due to Maternal Calorie Restriction

  2020cites this paper
• Decoding novel mechanisms and emerging therapeutic strategies in breast cancer resistance.

  2020cites this paper
• Polyphenols from mango (Mangifera indica L.) modulate PI3K/AKT/mTOR-associated micro-RNAs and reduce inflammation in non-cancer and induce cell death in breast cancer cells

  2019cites this paper
• Adaptive boosting-based computational model for predicting potential miRNA-disease associations

  2019cites this paper
• Differential microRNA expression profiles determined by next-generation sequencing in three fulvestrant-resistant human breast cancer cell lines

  2019cites this paper
• Emerging roles of exosomal miRNAs in breast cancer drug resistance

  2019cites this paper
• LOMDA: Linear optimization for miRNA-disease association prediction

  2019cites this paper
• A voltammetric hybridization assay for microRNA-21 using carboxylated graphene oxide decorated with gold-platinum bimetallic nanoparticles

  2019cites this paper
• Genome-Wide Profiling of Cardinium-Responsive MicroRNAs in the Exotic Whitefly, Bemisia tabaci (Gennadius) Biotype Q

  2018cites this paper
• Up-regulation of HOXB cluster genes are epigenetically regulated in tamoxifen-resistant MCF7 breast cancer cells

  2018cites this paper
• Estrogen Receptor Regulation of MicroRNAs in Breast Cancer

  2018cites this paper
• Seven shades of tamoxifen resistance : Molecular mechanisms of drug resistance in breast cancer

  2018cites this paper
• Role of MIR-29B-1 and MIR-29A in endocrine-resistant breast cancer.

  2017cites this paper
• Inferring MicroRNA-Disease Associations by Random Walk on a Heterogeneous Network with Multiple Data Sources

  2017cites this paper
• Small non-coding RNA and cancer

  2017cites this paper
• Oncogenic mechanisms of Lin28 in breast cancer: new functions and therapeutic opportunities

  2017cites this paper
• The role of exosomes and miRNAs in drug‐resistance of cancer cells

  2017cites this paper
• MicroRNAs in Breast Cancer: One More Turn in Regulation.

  2016cites this paper
• Critical role of miR-125b in lipogenesis by targeting stearoyl-CoA desaturase-1 (SCD-1).

  2016cites this paper
• Brain-metastatic Breast Cancer: Clinical Considerations and Pharmacological Approaches.

  2016cites this paper
• Iterative segmented least square method for functional microRNA-mRNA module discovery in breast cancer

  2016cites this paper
• Identification of targets of miRNA-221 and miRNA-222 in fulvestrant-resistant breast cancer

  2016cites this paper
• MiRSEA: Discovering the pathways regulated by dysfunctional MicroRNAs

  2016cites this paper
• Integrated analysis of omics data using microRNA-target mRNA network and PPI network reveals regulation of Gnai1 function in the spinal cord of Ews/Ewsr1 KO mice

  2016cites this paper
• miREFRWR: a novel disease-related microRNA-environmental factor interactions prediction method.

  2016cites this paper
• Alteraciones moleculares de la señalización estrogénica en el Cáncer de Mama con receptores hormonales positivos

  2016cites this paper
• The effect of Tamoxifen and Fulvestrant on pro-inflammatory markers in oestrogen receptor positive breast cancer

  2016cites this paper
• Bioinformatics Prediction and In Vitro Analysis Revealed That miR‐17 Targets Cyclin D1 mRNA in Triple Negative Breast Cancer Cells

  2016cites this paper
• miR-141 as potential suppressor of β-catenin in breast cancer

  2015cites this paper
• MicroRNA Profile in Response to Doxorubicin Treatment in Breast Cancer

  2015cites this paper
• Roles for miRNAs in endocrine resistance in breast cancer.

  2015cites this paper
• A Computational Approach to Identifying Gene-microRNA Modules in Cancer

  2015cites this paper
• BioVLAB-MMIA-NGS: microRNA-mRNA integrated analysis using high-throughput sequencing data

  2015cites this paper
• PlantMirnaT: miRNA and mRNA integrated analysis fully utilizing characteristics of plant sequencing data.

  2015cites this paper
• Bioinformatic tools for microRNA dissection

  2015cites this paper
• The Role of MicroRNAs in Kidney Disease

  2015cites this paper
• Molecular Modification of Metadherin/MTDH Impacts the Sensitivity of Breast Cancer to Doxorubicin

  2015cites this paper
• miRNA clusters as therapeutic targets for hormone-resistant breast cancer

  2015cites this paper
• Integration Analysis of MicroRNA and mRNA Expression Profiles in Human Peripheral Blood Lymphocytes Cultured in Modeled Microgravity

  2014cites this paper
• Prediction of therapeutic microRNA based on the human metabolic network

  2014cites this paper
• Semi-supervised learning for potential human microRNA-disease associations inference

  2014cites this paper
• Prediction of disease-related microRNAs by incorporating functional similarity and common association information.

  2014cites this paper
• Mechanisms associated with resistance to tamoxifen in estrogen receptor-positive breast cancer (review).

  2014cites this paper
• MicroRNAs and anticancer drugs.

  2014cites this paper
• Revisiting STAT3 signalling in cancer: new and unexpected biological functions

  2014cites this paper
• MicroRNAs in pathogenesis of breast cancer: Implications in diagnosis and treatment.

  2014cites this paper
• MicroRNA and Cancer Drug Resistance

  2014cites this paper
• TARGETED THERAPY FOR LIVER FIBROSIS AND CANCER

  2014cites this paper
• Functional interpretation of microRNA-mRNA association in biological systems using R

  2014cites this paper
• Control of Receptor Function by MicroRNAs in Breast Cancer

  2013cites this paper
• Endocrine resistance in breast cancer: Current status and a perspective on the roles of miRNAs (Review)

  2013influential citation
• Inhibition of p38 mitogen-activated protein kinase alters microRNA expression and reverses epithelial-to-mesenchymal transition

  2013cites this paper
• Comprehensive Analysis of MicroRNA (miRNA) Targets in Breast Cancer Cells*

  2013cites this paper
• miR-181b modulates glioma cell sensitivity to temozolomide by targeting MEK1

  2013cites this paper
• Characterization and Comparative Profiling of miRNAs in Invasive Bemisia tabaci (Gennadius) B and Q

  2013cites this paper
• Computational regulatory network construction from microRNA and transcription factor perspectives

  2013cites this paper
• MicroRNAs and drug resistance of breast cancer: basic evidence and clinical applications

  2013cites this paper
• MEK5/ERK5 Signaling Suppresses Estrogen Receptor Expression and Promotes Hormone-Independent Tumorigenesis

  2013cites this paper
• Comprehensive Analysis of miRNA Targets in Breast Cancer Cells *

  2013cites this paper
• Endocrine resistance in breast cancer: biological mechanisms and clinical implications to develop new treatment strategies

  2013cites this paper
• Integrated analysis of microRNA and mRNA expression: adding biological significance to microRNA target predictions

  2013cites this paper
• Mechanisms of Resistance to Endocrine Therapy in Breast Cancer: Focus on Signaling Pathways, miRNAs and Genetically Based Resistance

  2012cites this paper
• BioVLAB-MMIA: A Cloud Environment for microRNA and mRNA Integrated Analysis (MMIA) on Amazon EC2

  2012cites this paper
• The miRNA-drug resistance connection: a new era of personalized medicine using noncoding RNA begins.

  2012cites this paper
• Predicting miRNA-mediated gene silencing mode based on miRNA-target duplex features

  2012cites this paper
• miRNAs and estrogen action.

  2012cites this paper
• Molecular profiling: an essential technology enabling personalized medicine in breast cancer.

  2012cites this paper
• Epigenetic landscape and miRNA involvement during neural crest development

  2012cites this paper
• RWRMDA: predicting novel human microRNA-disease associations.

  2012cites this paper
• Analysis of miRNA and mRNA Expression Profiles Highlights Alterations in Ionizing Radiation Response of Human Lymphocytes under Modeled Microgravity

  2012cites this paper
• Differential expression of microRNA expression in tamoxifen-sensitive MCF-7 versus tamoxifen-resistant LY2 human breast cancer cells.

  2011cites this paper
• Roles of microRNA-29 a in the Antifibrotic Effect of Farnesoid X Receptor in Hepatic Stellate Cells

  2011cites this paper
• Epigenetic Regulation of microRNA Expression: Targeting the Triple-Negative Breast Cancer Phenotype

  2011influential citation
• Emerging role of microRNAs in drug-resistant breast cancer.

  2011cites this paper
• MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways

  2011cites this paper
• Role of MicroRNAs in Anti-cancer Drug Resistance

  2011cites this paper
• MicroRNAs and drug modulation in cancer: an intertwined new story

  2011cites this paper
• The DNA-Damage Response to Ionizing Radiation in Human Lymphocytes

  2011cites this paper
• Integrated Analysis of miRNA and mRNA Expression in Childhood Medulloblastoma Compared with Neural Stem Cells

  2011cites this paper