Pre-clinical and clinical evaluation of nuclear tracers for the molecular imaging of vulnerable atherosclerosis: an overview.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Current Medicinal Chemistry

• Publication date

  2009-03-31

• Fields of study

  Medicine

• Identifiers
  DOI 10.2174/092986709787909596PMID 19355903PMCID PMC2930153
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Annual Congress of the European Association of Nuclear Medicine

  2011cited by this paper
• J Nucl Med

  2010cited by this paper
• Preparation and bioevaluation of 99mTc-HYNIC-annexin B1 as a novel radioligand for apoptosis imaging

  2008cited by this paper
• The lectin-like oxidized low-density-lipoprotein receptor: a pro-inflammatory factor in vascular disease.

  2008cited by this paper
• Role of smooth muscle cells in the initiation and early progression of atherosclerosis.

  2008cited by this paper
• Small-Animal SPECT and SPECT/CT: Important Tools for Preclinical Investigation*

  2008cited by this paper
• Targeting of Lectinlike Oxidized Low-Density Lipoprotein Receptor 1 (LOX-1) with 99mTc-Labeled Anti–LOX-1 Antibody: Potential Agent for Imaging of Vulnerable Plaque

  2008cited by this paper
• Detection of Neovessels in Atherosclerotic Plaques of Rabbits Using Dynamic Contrast Enhanced MRI and 18F-FDG PET

  2008cited by this paper
• Noninvasive In Vivo Imaging of Monocyte Trafficking to Atherosclerotic Lesions

  2008cited by this paper
• Radionuclide imaging: a molecular key to the atherosclerotic plaque.

  2008cited by this paper
• Atherosclerotic lesion development and Toll like receptor 2 and 4 responsiveness.

  2008cited by this paper
• Nanoparticle PET-CT Imaging of Macrophages in Inflammatory Atherosclerosis

  2008cited by this paper
• A 18F-radiolabeled analogue of CGS 27023A as a potential agent for assessment of matrix-metalloproteinase activity in vivo.

  2007cited by this paper
• Current diagnostic modalities for vulnerable plaque detection.

  2007cited by this paper
• Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular, and vascular behavior.

  2007cited by this paper
• Human Antibody Against C Domain of Tenascin-C Visualizes Murine Atherosclerotic Plaques Ex Vivo

  2007cited by this paper
• (18)Fluorodeoxyglucose positron emission tomography imaging of atherosclerotic plaque inflammation is highly reproducible: implications for atherosclerosis therapy trials.

  2007cited by this paper
• Molecular Imaging of Inflammation in Atherosclerosis With Targeted Ultrasound Detection of Vascular Cell Adhesion Molecule-1

  2007cited by this paper
• The nonpeptidyl caspase binding radioligand (S)-1-(4-(2-[18F]Fluoroethoxy)-benzyl)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin ([18F]CbR) as potential positron emission tomography-compatible apoptosis imaging agent.

  2007cited by this paper
• Broad and specific caspase inhibitor-induced acute repression of apoptosis in atherosclerotic lesions evaluated by radiolabeled annexin A5 imaging.

  2007cited by this paper
• Response to 'Laurberg JM, Olsen AK, Hansen SB, et al. Imaging of vulnerable atherosclerotic plaques with FDG-microPET: no FDG accumulation' [Atherosclerosis 2006].

  2007cited by this paper
• Heart disease and stroke statistics--2008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee.

  2007cited by this paper
• Nuclear medicine applications in molecular imaging: 2007 update.

  2007cited by this paper
• The prevalence of inflammation in carotid atherosclerosis: analysis with fluorodeoxyglucose-positron emission tomography.

  2007cited by this paper
• Plaque neovascularization and antiangiogenic therapy for atherosclerosis.

  2007cited by this paper
• Radiolabeled Monocyte Chemotactic Protein 1 for the Detection of Inflammation in Experimental Atherosclerosis

  2007cited by this paper
• Vascular inflammation.

  2007cited by this paper
• 99mTc-Annexin A5 for noninvasive characterization of atherosclerotic lesions: imaging and histological studies in myocardial infarction-prone Watanabe heritable hyperlipidemic rabbits

  2007cited by this paper
• Imaging of vulnerable atherosclerotic plaques with FDG-microPET: no FDG accumulation.

  2007cited by this paper
• Novel fluorinated derivatives of the broad-spectrum MMP inhibitors N-hydroxy-2(R)-[[(4-methoxyphenyl)sulfonyl](benzyl)- and (3-picolyl)-amino]-3-methyl-butanamide as potential tools for the molecular imaging of activated MMPs with PET.

  2007cited by this paper
• Molecular imaging of vascular cell adhesion molecule-1 expression in experimental atherosclerotic plaques with radiolabelled B2702-p

  2007influential reference
• Comparison of 99mTc-annexin A5 with 18F-FDG for the detection of atherosclerosis in ApoE−/− mice

  2007cited by this paper
• Vascular inflammation evaluated by [18F]-fluorodeoxyglucose positron emission tomography is associated with the metabolic syndrome.

  2007cited by this paper
• CD40 and its ligand in atherosclerosis.

  2007influential reference
• State-of-the-art of PET, SPECT and CT for small animal imaging

  2007cited by this paper
• Molecular imaging of cell death in vivo by a novel small molecule probe

  2006cited by this paper
• Noninvasive imaging of atherosclerotic lesions in apolipoprotein E-deficient and low-density-lipoprotein receptor-deficient mice with annexin A5.

  2006cited by this paper
• Heart disease and stroke statistics--2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee.

  2006cited by this paper
• Atherosclerosis and the Lectin-like OXidized low-density lipoprotein scavenger receptor.

  2006cited by this paper
• Tissue Factor in Cardiovascular Diseases: Molecular Mechanisms and Clinical Implications

  2006cited by this paper
• Noninvasive Vascular Cell Adhesion Molecule-1 Imaging Identifies Inflammatory Activation of Cells in Atherosclerosis

  2006cited by this paper
• From vulnerable plaque to vulnerable patient--Part III: Executive summary of the Screening for Heart Attack Prevention and Education (SHAPE) Task Force report.

  2006cited by this paper
• Endothelial mechanotransduction, nitric oxide and vascular inflammation

  2006cited by this paper
• Radionuclide imaging for the detection of inflammation in vulnerable plaques.

  2006cited by this paper
• In vivo 18F-fluorodeoxyglucose positron emission tomography imaging provides a noninvasive measure of carotid plaque inflammation in patients.

  2006cited by this paper
• Do metalloproteinases destabilize vulnerable atherosclerotic plaques?

  2006cited by this paper
• Positron autoradiography for intravascular imaging: feasibility evaluation

  2006cited by this paper
• Application of 18F-FDG PET for monitoring the therapeutic effect of antiinflammatory drugs on stabilization of vulnerable atherosclerotic plaques.

  2006cited by this paper
• Colony-stimulating factor-1 in immunity and inflammation.

  2006cited by this paper
• Intravascular radiation detectors for the detection of vulnerable atheroma.

  2006cited by this paper
• Simvastatin attenuates plaque inflammation: evaluation by fluorodeoxyglucose positron emission tomography.

  2006cited by this paper
• A catheter-based intravascular radiation detector of vulnerable plaques.

  2006cited by this paper
• Fluorocholine PET/CT in patients with prostate cancer: initial experience.

  2005cited by this paper
• Atherothrombosis and high-risk plaque: part I: evolving concepts.

  2005influential reference
• C-5-disubstituted barbiturates as potential molecular probes for noninvasive matrix metalloproteinase imaging.

  2005cited by this paper
• 131I-labeled peptides as caspase substrates for apoptosis imaging.

  2005cited by this paper
• Detection of Vascular Adhesion Molecule-1 Expression Using a Novel Multimodal Nanoparticle

  2005cited by this paper
• 18F-Choline Images Murine Atherosclerotic Plaques Ex Vivo

  2005cited by this paper
• Noninvasive in vivo measurement of vascular inflammation with F-18 fluorodeoxyglucose positron emission tomography

  2005cited by this paper
• 99mTc-annexin V imaging for in vivo detection of atherosclerotic lesions in porcine coronary arteries.

  2005cited by this paper
• Resolution of apoptosis in atherosclerotic plaque by dietary modification and statin therapy.

  2005cited by this paper
• Noninvasive detection of plaque instability with use of radiolabeled annexin A5 in patients with carotid-artery atherosclerosis.

  2004cited by this paper
• Molecular Imaging of Atherosclerotic Plaques Using a Human Antibody Against the Extra-Domain B of Fibronectin

  2004cited by this paper
• (18)F-FDG accumulation in atherosclerotic plaques: immunohistochemical and PET imaging study.

  2004influential reference
• Intravascular ultrasound molecular imaging of atheroma components in vivo.

  2004cited by this paper
• Plaque Neovascularization Is Increased in Ruptured Atherosclerotic Lesions of Human Aorta: Implications for Plaque Vulnerability

  2004cited by this paper
• Role of Toll‐like receptor 4 in the initiation and progression of atherosclerotic disease

  2004cited by this paper
• Detection of Injury-Induced Vascular Remodeling by Targeting Activated &agr;vβ3 Integrin In Vivo

  2004cited by this paper
• Molecular imaging of atherosclerotic plaques with technetium-99m-labelled antisense oligonucleotides

  2004cited by this paper
• 18F-choline in experimental soft tissue infection assessed with autoradiography and high-resolution PET

  2004cited by this paper
• Vulnerable plaque: the devil is in the details.

  2004cited by this paper
• Anti-genes: siRNA, ribozymes and antisense.

  2004cited by this paper
• Low density lipoprotein labelling characterizes experimentally induced atherosclerotic lesions in rabbits in vivo as to presence of foam cells and endothelial coverage

  2004cited by this paper
• Reduced In Vivo Aortic Uptake of Radiolabeled Oxidation-Specific Antibodies Reflects Changes in Plaque Composition Consistent With Plaque Stabilization

  2004cited by this paper
• Detection of injury-induced vascular remodeling by targeting activated alphavbeta3 integrin in vivo.

  2004cited by this paper
• Uptake of 18F-fluorocholine, 18F-fluoroethyl-L-tyrosine, and 18F-FDG in acute cerebral radiation injury in the rat: implications for separation of radiation necrosis from tumor recurrence.

  2004cited by this paper
• Scintigraphic Imaging of Matrix Metalloproteinase Activity in the Arterial Wall In Vivo

  2004cited by this paper
• A catheter-based radiation detector for endovascular detection of atheromatous plaques

  2004cited by this paper
• Synthesis and preliminary biological evaluation of new radioiodinated MMP inhibitors for imaging MMP activity in vivo.

  2004cited by this paper
• Safety, biodistribution, and dosimetry of 99mTc-HYNIC-annexin V, a novel human recombinant annexin V for human application.

  2003cited by this paper
• From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II.

  2003cited by this paper
• Targeting of Apoptotic Macrophages and Experimental Atheroma With Radiolabeled Annexin V: A Technique With Potential for Noninvasive Imaging of Vulnerable Plaque

  2003cited by this paper
• Atlas of Atherosclerosis Progression and Regression

  2003influential reference
• From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I.

  2003cited by this paper
• Targeting of endothelin receptors for molecular imaging of atherosclerosis in rabbits.

  2002cited by this paper
• Nuclear medicine applications in molecular imaging

  2002cited by this paper
• Noninvasive imaging of oxidized low-density lipoprotein in atherosclerotic plaques with tagged oxidation-specific antibodies.

  2002cited by this paper
• Imaging Atherosclerotic Plaque Inflammation With [18F]-Fluorodeoxyglucose Positron Emission Tomography

  2002cited by this paper
• Atherogenesis in perspective: Hypercholesterolemia and inflammation as partners in crime

  2002cited by this paper
• Detection of atherosclerosis using a novel positron-sensitive probe and 18-fluorodeoxyglucose (FDG)

  2001cited by this paper
• Coronary intravascular ultrasound: implications for understanding the development and potential regression of atherosclerosis.

  2001cited by this paper
• VCAM-1 is critical in atherosclerosis.

  2001cited by this paper
• c-myc activation in early coronary lesions in experimental hypercholesterolemia.

  2001cited by this paper
• Atherosclerosis The Road Ahead

  2001cited by this paper
• Detection of Monocyte Chemoattractant Protein-1 Receptor Expression in Experimental Atherosclerotic Lesions: An Autoradiographic Study

  2001cited by this paper
• Apoptosis as a Determinant of Atherothrombosis

  2001cited by this paper
• Tc-99m-labeled endothelin derivative for imaging of experimentally induced atherosclerosis.

  2001cited by this paper
• Endothelial function and coronary artery disease

  2001cited by this paper
• Atlas of atherosclerosis progression and regression. Herbert C. Stary, Parthenon publishing, ISBN 1-85070-480-5

  2001cited by this paper
• NF-κB: pivotal mediator or innocent bystander in atherogenesis?

  2001cited by this paper

• In vivo SPECT/CT molecular imaging of LFA-1 in atherosclerotic inflammatory development with radiolabeled DANBIRT

  2016cites this paper
• Modélisation, simulation et quantification de lésions athéromateuses en tomographie par émission de positons. (Numerical modeling, simulation and quantification of atheromatous lesions in positron emission tomography)

  2015cites this paper
• Higher reliability of 18F-FDG target background ratio compared to standardized uptake value in vulnerable carotid plaque detection: a pilot study

  2014cites this paper
• Vaskuläre Pharmakodiagnostik und Pharmakotherapie

  2014cites this paper
• Inflammation, Atherosclerosis, and Coronary Artery Disease: PET/CT for the Evaluation of Atherosclerosis and Inflammation

  2014cites this paper
• Visualizing the atherosclerotic plaque: a chemical perspective.

  2014cites this paper
• Advances in Radiotracer Development for Molecular Imaging

  2014cites this paper
• Radioiodinated peptide probe for selective detection of oxidized low density lipoprotein in atherosclerotic plaques.

  2013cites this paper
• Positron Emission Tomography Imaging of Atherosclerosis

  2013cites this paper
• In Vivo Molecular Imaging of Atherosclerotic Lesions in ApoE−/− Mice Using VCAM-1–Specific, 99mTc-Labeled Peptidic Sequences

  2013cites this paper
• In Vivo Molecular Imaging of Atherosclerotic Lesions in ApoE-/-mice using VCAM-1-Specific , 99 m Tc-Labeled Peptidic Sequences

  2013cites this paper
• Attenuation of Apoptosis by Telmisartan in Atherosclerotic Plaques of Apolipoprotein E−/− Mice: Evaluation Using Technetium 99m–Annexin A5

  2013cites this paper
• Caractérisation et imagerie moléculaire de la plaque d'athérome : études pré-cliniques

  2013cites this paper
• Small animal positron emission tomography imaging and in vivo studies of atherosclerosis

  2013cites this paper
• Nanobodies Targeting Mouse/Human VCAM1 for the Nuclear Imaging of Atherosclerotic Lesions

  2012cites this paper
• Radiolabelled probes for imaging of atherosclerotic plaques.

  2012cites this paper
• Vulnerable plaque and inflammation: potential clinical strategies.

  2011cites this paper
• Molecular Imaging Probe Development using Microfluidics.

  2011cites this paper
• Regional Atherosclerotic Plaque Properties in ApoE–/– Mice Quantified by Atomic Force, Immunofluorescence, and Light Microscopy

  2011cites this paper
• Mechanics of atherosclerosis, hypertension induced growth, and arterial remodeling

  2011cites this paper
• The Vulnerable Atherosclerotic Plaque: Scope of the Literature

  2010cites this paper
• Number 3 Vulnerable Atherosclerotic Plaque

  2010cites this paper
• Nanobodies as Tools for In Vivo Imaging of Specific Immune Cell Types

  2010cites this paper
• Do free radicals play causal role in atherosclerosis? Low density lipoprotein oxidation and vitamin E revisited

  2010cites this paper
• Appendix Table 1. References of Primary Studies and Narrative Review Articles

  year unknowncites this paper