Cryptic peroxisomal targeting via alternative splicing and stop codon read-through in fungi

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Nature

• Publication date

  2012-05-23

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/nature11051PMID 22622582
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A peroxisomal carrier delivers NAD⁺ and contributes to optimal fatty acid degradation during storage oil mobilization.

  2012cited by this paper
• Alternative splicing directs dual localization of Candida albicans 6-phosphogluconate dehydrogenase to cytosol and peroxisomes.

  2012cited by this paper
• Alternative Splicing Regulates Targeting of Malate Dehydrogenase in Yarrowia lipolytica

  2012cited by this paper
• Fungal evo-devo: organelles and multicellular complexity.

  2011cited by this paper
• A proteomic approach towards the identification of the matrix protein content of the two types of microbodies in Neurospora crassa

  2010cited by this paper
• Peroxisome diversity and evolution

  2010cited by this paper
• Peroxisomal protein translocation.

  2010cited by this paper
• Matching the proteome to the genome: the microbody of penicillin-producing Penicillium chrysogenum cells

  2009cited by this paper
• The Vienna RNA Websuite

  2008cited by this paper
• Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes

  2008cited by this paper
• Seed storage oil mobilization.

  2008cited by this paper
• Coordination of cytokinesis and cell separation by endosomal targeting of a Cdc42-specific guanine nucleotide exchange factor in Ustilago maydis.

  2008cited by this paper
• Metabolite transport across the peroxisomal membrane.

  2007cited by this paper
• Formation of peroxisomes: present and past.

  2006cited by this paper
• The import receptor Pex7p and the PTS2 targeting sequence.

  2006cited by this paper
• Insights from the genome of the biotrophic fungal plant pathogen Ustilago maydis

  2006cited by this paper
• Peroxisome Function Regulates Growth on Glucose in the Basidiomycete Fungus Cryptococcus neoformans

  2006cited by this paper
• Peroxisomal beta-oxidation--a metabolic pathway with multiple functions.

  2006cited by this paper
• The ins and outs of peroxisomes: co-ordination of membrane transport and peroxisomal metabolism.

  2006cited by this paper
• Peroxisome targeting signal 1: is it really a simple tripeptide?

  2006cited by this paper
• Peroxisomal β-oxidation—A metabolic pathway with multiple functions

  2006cited by this paper
• Metabolic functions of glycosomes in trypanosomatids.

  2006cited by this paper
• PEX Genes in Fungal Genomes: Common, Rare or Redundant

  2006cited by this paper
• Contribution of the endoplasmic reticulum to peroxisome formation.

  2005cited by this paper
• A reverse genetic approach for generating gene replacement mutants in Ustilago maydis

  2004cited by this paper
• A reverse genetic approach for generating gene replacement mutants in Ustilago maydis

  2004cited by this paper
• A versatile toolbox for PCR‐based tagging of yeast genes: new fluorescent proteins, more markers and promoter substitution cassettes

  2004cited by this paper
• Prediction of peroxisomal targeting signal 1 containing proteins from amino acid sequence.

  2003cited by this paper
• Recoding: translational bifurcations in gene expression.

  2002cited by this paper
• Molecular Cloning: A Laboratory Manual

  2001cited by this paper
• Peroxisome biogenesis.

  2001cited by this paper
• A homologue of the transcriptional repressor Ssn6p antagonizes cAMP signalling in Ustilago maydis

  2001cited by this paper
• Identification of Peroxisomal Acyl-CoA Thioesterases in Yeast and Humans*

  1999cited by this paper
• The danger of metabolic pathways with turbo design.

  1998cited by this paper
• The Saccharomyces cerevisiae Peroxisomal 2,4-Dienoyl-CoA Reductase Is Encoded by the Oleate-inducible GeneSPS19 *

  1997cited by this paper
• Peroxisome biogenesis

  1997cited by this paper
• Green fluorescent protein (GFP) as a new vital marker in the phytopathogenic fungus Ustilago maydis.

  1996cited by this paper
• Green fluorescent protein (GFP) as a new vital marker in the phytopathogenic fungus

  1996cited by this paper
• The membrane of peroxisomes in Saccharomyces cerevisiae is impermeable to NAD(H) and acetyl‐CoA under in vivo conditions.

  1995cited by this paper
• The b alleles of U. maydis, whose combinations program pathogenic development, code for polypeptides containing a homeodomain-related motif.

  1990cited by this paper
• A conserved tripeptide sorts proteins to peroxisomes

  1989cited by this paper
• A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli.

  1987cited by this paper
• Present and Past

  1981cited by this paper
• Peroxisomes (microbodies and related particles).

  1966cited by this paper

• Adaptive Plasticity of Phytochelatin Synthase Under Chromium Stress and Sulfur Availability in Scenedesmus acutus

  2026cites this paper
• Jasmonate-Mediated Defense Coordination in the Cereal–Pathogen Arms Race

  2026cites this paper
• Exploring glycolytic enzymes in disease: potential biomarkers and therapeutic targets in neurodegeneration, cancer and parasitic infections

  2025cites this paper
• Homology-mediated transformation of frog-killing fungus Batrachochytrium dendrobatidis illuminates chytrid development and pathogenesis

  2025cites this paper
• Bulk and selective autophagy cooperate to remodel a fungal proteome in response to changing nutrient availability.

  2025cites this paper
• Light controls gene functions through alternative splicing in fungi

  2025cites this paper
• A non-canonical fungal peroxisome PTS-1 signal, SYM, and its evolutionary aspects

  2025influential citation
• Mechanistic and structural insights into the itaconate-producing trans-aconitate decarboxylase Tad1

  2025cites this paper
• Two gene clusters are required for mannosylerythritol lipid biosynthesis in Sporisorium reilianum

  2025cites this paper
• Peroxisomal core structures segregate diverse metabolic pathways

  2025cites this paper
• New insights into the functions of ACBD4/5-like proteins using a combined phylogenetic and experimental approach across model organisms

  2024cites this paper
• Proteins that carry dual targeting signals can act as tethers between peroxisomes and partner organelles

  2024cites this paper
• Readthrough events in plants reveal plasticity of stop codons.

  2024cites this paper
• Host-pathogen interaction between pitaya and Neoscytalidium dimidiatum reveals the mechanisms of immune response associated with defense regulators and metabolic pathways

  2024cites this paper
• Human eRT1 Translation Regulation

  2024cites this paper
• Transcriptome analysis of two isolates of the tomato pathogen Cladosporium fulvum, uncovers genome-wide patterns of alternative splicing during a host infection cycle

  2024cites this paper
• Salmonella Typhimurium effector SseI regulates host peroxisomal dynamics to acquire lysosomal cholesterol

  2024cites this paper
• Bulk and selective autophagy cooperate to remodel a fungal proteome in response to changing nutrient availability

  2024cites this paper
• Human eRF1 Translation Regulation

  2024cites this paper
• Environment modulates protein heterogeneity through transcriptional and translational stop codon readthrough

  2024cites this paper
• Distal nucleotides affect the rate of stop codon read‐through

  2023cites this paper
• Environment Modulates Protein Heterogeneity Through Transcriptional and Translational Stop Codon Miscoding

  2023cites this paper
• Peroxin Pex14/17 Is Required for Trap Formation, and Plays Pleiotropic Roles in Mycelial Development, Stress Response, and Secondary Metabolism in Arthrobotrys oligospora

  2023cites this paper
• Salmonella Typhimurium effector SseI regulates host peroxisomal dynamics to acquire lysosomal cholesterol for better intracellular growth

  2023cites this paper
• The RNA world of fungal pathogens

  2023cites this paper
• Reconstruction of compartmentalized genome-scale metabolic models using deep learning for over 800 fungi

  2023cites this paper
• C-terminal sequence stability profiling in Saccharomyces cerevisiae reveals protective protein quality control pathways

  2023cites this paper
• Investigating the Inhibition of FTSJ1, a Tryptophan tRNA-Specific 2′-O-Methyltransferase by NV TRIDs, as a Mechanism of Readthrough in Nonsense Mutated CFTR

  2023cites this paper
• Widespread readthrough events in plants reveal unprecedented plasticity of stop codons

  2023cites this paper
• A novel function for eukaryotic elongation factor 3: Inhibition of stop codon readthrough in yeast.

  2023cites this paper
• Two Pex5 Proteins With Different Cargo Specificity Are Critical for Peroxisome Function in Ustilago maydis

  2022influential citation
• Alternative splicing reprogramming in fungal pathogen Sclerotinia sclerotiorum at different infection stages on Brassica napus

  2022cites this paper
• Sharing the wealth: The versatility of proteins targeted to peroxisomes and other organelles

  2022influential citation
• Delineating transitions during the evolution of specialised peroxisomes: Glycosome formation in kinetoplastid and diplonemid protists

  2022influential citation
• Import and Export of Mannosylerythritol Lipids by Ustilago maydis

  2022cites this paper
• Unraveling usnic acid: a comparison of biosynthetic gene clusters between two reindeer lichen (Cladonia rangiferina and C. uncialis).

  2022cites this paper
• Phenotypic mutations contribute to protein diversity and shape protein evolution

  2022cites this paper
• Dually targeted proteins regulate proximity between peroxisomes and partner organelles

  2022cites this paper
• Exploring Yeast Diversity to Produce Lipid-Based Biofuels from Agro-Forestry and Industrial Organic Residues

  2022cites this paper
• Recognition of 3′ nucleotide context and stop codon readthrough are determined during mRNA translation elongation

  2022cites this paper
• Peroxins in Peroxisomal Receptor Export System Contribute to Development, Stress Response, and Virulence of Insect Pathogenic Fungus Beauveria bassiana

  2022cites this paper
• Recent Advances in Research on Molecular Mechanisms of Fungal Signaling

  2022cites this paper
• Evasion of plant immunity by microbial pathogens

  2022cites this paper
• Biogenesis and metabolic homeostasis of trypanosomatid glycosomes: New insights and new questions

  2022cites this paper
• Neofunctionalization of Glycolytic Enzymes: An Evolutionary Route to Plant Parasitism in the Oomycete Phytophthora nicotianae

  2022cites this paper
• BiFC Method Based on Intraorganellar Protein Crowding Detects Oleate-Dependent Peroxisomal Targeting of Pichia pastoris Malate Dehydrogenase

  2021cites this paper
• Versatile allosteric properties in Pex5‐like tetratricopeptide repeat proteins to induce diverse downstream function

  2021cites this paper
• Nonsense suppression therapies in human genetic diseases

  2021cites this paper
• Eukaryotic ribosome recognizes 3′ context and stimulates stop codon readthrough

  2021cites this paper
• Evolucija ključnih peroksisomalnih proteina

  2021cites this paper
• Silent control: microbial plant pathogens evade host immunity without coding sequence changes.

  2021cites this paper
• Systematic multi‐level analysis of an organelle proteome reveals new peroxisomal functions

  2021cites this paper
• Landscape, complexity and regulation of a filamentous fungal transcriptome

  2021cites this paper
• Pex7 selectively imports PTS2 target proteins to peroxisomes and is required for anthracnose disease development in Colletotrichum scovillei.

  2021cites this paper
• Intron distribution and emerging role of alternative splicing in fungi.

  2021cites this paper
• Versatile CRISPR/Cas9 Systems for Genome Editing in Ustilago maydis

  2021cites this paper
• Translational read-through promotes aggregation and shapes stop codon identity

  2020cites this paper
• Origin, conservation, and loss of alternative splicing events that diversify the proteome in Saccharomycotina budding yeasts

  2020cites this paper
• A Global Analysis of Enzyme Compartmentalization to Glycosomes

  2020cites this paper
• Biochemical and molecular investigations of benzoic acid metabolism in Hypericum calycinum cell cultures

  2020cites this paper
• Non-AUG Translation Initiation Generates Peroxisomal Isoforms of 6-Phosphogluconate Dehydrogenase in Fungi

  2020cites this paper
• The occurrence and function of alternative splicing in fungi

  2020cites this paper
• Genome‐wide alternative splicing profiling in the fungal plant pathogen Sclerotinia sclerotiorum during the colonization of diverse host families

  2020cites this paper
• Deciphering the molecular mechanism of stop codon readthrough

  2020cites this paper
• A promiscuous CoA ligase provides benzoyl-CoA for xanthone biosynthesis in Hypericum.

  2020cites this paper
• Expression of the translation termination factor eRF1 is autoregulated by translational readthrough and 3'UTR intron‐mediated NMD in Neurospora crassa

  2020cites this paper
• Stop codon readthrough of a POU transcription factor regulates steroidogenesis and developmental transitions

  2020cites this paper
• Genome-wide alternative splicing profiling in the fungal plant pathogen Sclerotinia sclerotiorum during the colonization of diverse host families

  2020cites this paper
• Peroxisomal targeting of a protein phosphatase type 2C via mitochondrial transit

  2020cites this paper
• Translational readthrough goes unseen by natural selection

  2019cites this paper
• Reconstructing the complex evolutionary history of the fused Aco2 gene in fission yeast

  2019cites this paper
• Stop codon context influences genome-wide stimulation of termination codon readthrough by aminoglycosides

  2019cites this paper
• Translational recoding: canonical translation mechanisms reinterpreted

  2019cites this paper
• Membrane-Associated RNA-Binding Proteins Orchestrate Organelle-Coupled Translation.

  2019cites this paper
• Interrogation of Eukaryotic Stop Codon Readthrough Signals by in Vitro RNA Selection.

  2019cites this paper
• A-to-I mRNA editing in fungi: occurrence, function, and evolution

  2018cites this paper
• UGA stop codon readthrough to translate intergenic region of Plautia stali intestine virus does not require RNA structures forming internal ribosomal entry site

  2018influential citation
• The Obvious and the Hidden: Prediction and Function of Fungal Peroxisomal Matrix Proteins.

  2018cites this paper
• Predicting Peroxisomal Targeting Signals to Elucidate the Peroxisomal Proteome of Mammals.

  2018cites this paper
• Stop codon readthrough generates a C-terminally extended variant of the human vitamin D receptor with reduced calcitriol response

  2018cites this paper
• Adapt your shuttling proteins for virulence: a lesson from the corn smut fungus Ustilago maydis.

  2018cites this paper
• The Proteome of Fruit Peroxisomes: Sweet Pepper (Capsicum annuum L.) as a Model.

  2018cites this paper
• Multiple Localization by Functional Translational Readthrough.

  2018cites this paper
• EVOLUTION VIA GENE DUPLICATION AND ALTERNATIVE SPLICING IN THE EUKARYOTIC SKI7 AND HBS1 GENES

  2018influential citation
• A community-driven reconstruction of the Aspergillus niger metabolic network

  2018cites this paper
• Mitochondrial targeting of glycolysis in a major lineage of eukaryotes

  2018cites this paper
• The causes of evolvability and their evolution

  2018cites this paper
• Novel variant of the human vitamin D receptor

  2018cites this paper
• Contribution of peroxisomal protein importer AflPex5 to development and pathogenesis in the fungus Aspergillus flavus

  2018cites this paper
• Virulence function of the Ustilago maydis sterol carrier protein 2.

  2018cites this paper
• Peroxisomes and peroxisomal transketolase and transaldolase enzymes are essential for xylose alcoholic fermentation by the methylotrophic thermotolerant yeast, Ogataea (Hansenula) polymorpha

  2018cites this paper
• Mitochondrial Glycolysis in a Major Lineage of Eukaryotes

  2018cites this paper
• Robustness by intrinsically disordered C-termini and translational readthrough

  2018cites this paper
• Peroxisomal Dysfunction in Age-Related Diseases.

  2017cites this paper
• Transcriptome analysis reveals the host selection fitness mechanisms of the Rhizoctonia solani AG1IA pathogen

  2017cites this paper
• Genomic and Proteomic Evidence for the Presence of a Peroxisome in the Apicomplexan Parasite Toxoplasma gondii and Other Coccidia

  2017cites this paper
• Expression of the eRF1 translation termination factor is controlled by an autoregulatory circuit involving readthrough and nonsense-mediated decay in plants

  2017cites this paper
• Neue Isoformen für alte Enzyme durch translationalen readthrough

  2017cites this paper
• Alternative splicing affects the targeting sequence of peroxisome proteins in Arabidopsis

  2017cites this paper
• Triphenyltin degradation and proteomic response by an engineered Escherichia coli expressing cytochrome P450 enzyme.

  2017cites this paper