Wnt signaling induces matrix metalloproteinase expression and regulates T cell transmigration.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Immunity

• Publication date

  2007-02-23

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.IMMUNI.2006.12.007PMID 17306568PMCID PMC1855210
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Overexpression of ICAT highlights a rolefor catenin‐mediated canonical Wnt signalling in early T cell development

  2006cited by this paper
• Dense fibrillar collagen matrices: a model to study myofibroblast behaviour during wound healing.

  2006influential reference
• Transcriptional Regulation of CD4 Gene Expression by T Cell Factor-1/β-Catenin Pathway

  2006cited by this paper
• Wnt Signaling: Multiple Pathways, Multiple Receptors, and Multiple Transcription Factors*

  2006cited by this paper
• Wnts induce migration and invasion of myeloma plasma cells.

  2005cited by this paper
• Regulation by the extracellular matrix (ECM) of prolactin‐induced αs1‐casein gene expression in rabbit primary mammary cells: Role of STAT5, C/EBP, and chromatin structure

  2005cited by this paper
• WNT signalling and haematopoiesis: a WNT–WNT situation

  2005cited by this paper
• Beta-catenin regulates the gene of MMP-26, a novel metalloproteinase expressed both in carcinomas and normal epithelial cells.

  2004cited by this paper
• A mechanism for Wnt coreceptor activation.

  2004cited by this paper
• β-Catenin regulates the gene of MMP-26, a novel matrix metalloproteinase expressed both in carcinomas and normal epithelial cells

  2004cited by this paper
• β-Catenin Is Dispensable for Hematopoiesis and Lymphopoiesis

  2004cited by this paper
• WNT and beta-catenin signalling: diseases and therapies.

  2004cited by this paper
• WNT and β-catenin signalling: diseases and therapies

  2004cited by this paper
• Wnt11 Signaling Promotes Proliferation, Transformation, and Migration of IEC6 Intestinal Epithelial Cells*

  2004influential reference
• The Wnt signaling pathway in development and disease.

  2004cited by this paper
• Wnt-1 signaling inhibits human umbilical vein endothelial cell proliferation and alters cell morphology.

  2003cited by this paper
• Amoeboid shape change and contact guidance: T-lymphocyte crawling through fibrillar collagen is independent of matrix remodeling by MMPs and other proteases.

  2003cited by this paper
• Abnormalities of basement membrane on blood vessels and endothelial sprouts in tumors.

  2003cited by this paper
• Redundant functions of TCF‐1 and LEF‐1 during T and NK cell development, but unique role of TCF‐1 for Ly49 NK cell receptor acquisition

  2003cited by this paper
• Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response.

  2003cited by this paper
• Deletion of β-catenin impairs T cell development

  2003cited by this paper
• The Writ-1 (in&l) Proto-Oncogene Is Required for Development of a Large Region of the Mouse Brain

  2003cited by this paper
• Deletion of beta-catenin impairs T cell development.

  2003cited by this paper
• Astilbin suppresses delayed‐type hypersensitivity by inhibiting lymphocyte migration

  2003influential reference
• Role of integrins in cell invasion and migration

  2002cited by this paper
• Promoter characterization of the novel human matrix metalloproteinase-26 gene: regulation by the T-cell factor-4 implies specific expression of the gene in cancer cells of epithelial origin.

  2002cited by this paper
• Networks and crosstalk: integrin signalling spreads

  2002cited by this paper
• Regulation of epithelial cell migration and tumor formation by beta-catenin signaling.

  2002influential reference
• Tensile mechanical properties of three-dimensional type I collagen extracellular matrices with varied microstructure.

  2002influential reference
• Regulation of leukemic cell adhesion, proliferation, and survival by beta-catenin.

  2002cited by this paper
• Matrilysin shedding of syndecan-1 regulates chemokine mobilization and transepithelial efflux of neutrophils in acute lung injury.

  2002cited by this paper
• Differential role of E-selectin and P-selectin in T lymphocyte migration to cutaneous inflammatory reactions induced by cytokines.

  2002cited by this paper
• From rolling to arrest on blood vessels: leukocyte tap dancing on endothelial integrin ligands and chemokines at sub-second contacts.

  2002cited by this paper
• Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma.

  2002influential reference
• Alpha lipoic acid inhibits T cell migration into the spinal cord and suppresses and treats experimental autoimmune encephalomyelitis.

  2002influential reference
• Wnt‐1 and Wnt‐4 regulate thymic cellularity

  2002cited by this paper
• CD99 plays a major role in the migration of monocytes through endothelial junctions

  2002cited by this paper
• Endothelial Cells Stimulate T Cell NFAT Nuclear Translocation in the Presence of Cyclosporin A: Involvement of the wnt/Glycogen Synthase Kinase-3β Pathway1

  2002influential reference
• DIRECT EVIDENCE FOR A ROLE OF β‐CATENIN/LEF‐1 SIGNALING PATHWAY IN INDUCTION OF EMT

  2002cited by this paper
• The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival.

  2001cited by this paper
• Endothelial Cell Laminin Isoforms, Laminins 8 and 10, Play Decisive Roles in T Cell Recruitment across the Blood–Brain Barrier in Experimental Autoimmune Encephalomyelitis

  2001influential reference
• The β-catenin–TCF-1 pathway ensures CD4+CD8+ thymocyte survival

  2001cited by this paper
• Cell Migration in the Immune System: the Evolving Inter-Related Roles of Adhesion Molecules and Proteinases

  2000influential reference
• LDL-receptor-related proteins in Wnt signal transduction

  2000influential reference
• Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation

  2000cited by this paper
• The Yin-Yang of TCF/beta-catenin signaling.

  2000cited by this paper
• Adhesion molecule cascades direct lymphocyte recirculation and leukocyte migration during inflammation

  2000cited by this paper
• Inhibition of matrix metalloproteinases prevents allergen-induced airway inflammation in a murine model of asthma.

  1999influential reference
• Identification of a Wnt-responsive signal transduction pathway in primary endothelial cells.

  1999cited by this paper
• The metalloproteinase matrilysin is a target of β-catenin transactivation in intestinal tumors

  1999influential reference
• The interrelationship of alpha4 integrin and matrix metalloproteinase-2 in the pathogenesis of experimental autoimmune encephalomyelitis.

  1998influential reference
• Mechanisms of Wnt signaling in development.

  1998influential reference
• Axin, an inhibitor of the Wnt signalling pathway, interacts with β‐catenin, GSK‐3β and APC and reduces the β‐catenin level

  1998cited by this paper
• Critical involvement of Tcf-1 in expansion of thymocytes.

  1998cited by this paper
• T cell adhesion to endothelial cells and extracellular matrix is modulated upon transendothelial cell migration.

  1997cited by this paper
• Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC−/− Colon Carcinoma

  1997cited by this paper
• Matrix metalloproteinases in immunity.

  1996cited by this paper
• The roles of adhesion molecules and proteinases in lymphocyte transendothelial migration.

  1996influential reference
• Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4

  1994cited by this paper
• Wnt-3a regulates somite and tailbud formation in the mouse embryo.

  1994cited by this paper
• PECAM-1 is required for transendothelial migration of leukocytes

  1993cited by this paper
• Endothelial cells augment T cell interleukin 2 production by a contact- dependent mechanism involving CD2/LFA-3 interaction

  1990cited by this paper
• Ultrastructural studies of perivascular cuffing cells in multiple sclerosis brain.

  1975cited by this paper

• When Healing Turns Fibrotic: Exploring Molecular Mechanisms and Therapeutic Strategies for Knee Arthrofibrosis.

  2026cites this paper
• Hemoglobin alpha regulates T-lymphocyte activation and mitochondrial function

  2026cites this paper
• SLC7A11 in Fibrosis: Molecular Mechanisms and Future Prospects

  2025cites this paper
• Cardiac Fibroblasts: Helping or Hurting

  2025cites this paper
• Recombinant human collagen XVII protects skin basement membrane integrity by inhibiting the MAPK and Wnt signaling pathways

  2025cites this paper
• Identification of MMP gene family and their expression profiles during scale development in Gymnocypris przewalskii.

  2025cites this paper
• CD200 Promotes Gastric Cancer Progression and Metastasis by Inducing the β‐catenin Signaling Pathway

  2025cites this paper
• Cell migration in diabetic wound healing: Molecular mechanisms and therapeutic strategies (Review)

  2025cites this paper
• Levobupivacaine Administration Suppressed Cell Metabolism in Human Adenocarcinoma A549 Cells

  2025cites this paper
• Wnt9b enables androgen action to maintain Wolffian ducts in mice.

  2025cites this paper
• Wnt signaling - using the bloodstream to send a message

  2025cites this paper
• OH2 oncolytic virus inhibits non-small-cell lung cancer metastasis via β-catenin pathway suppression

  2025cites this paper
• A diarylheptanoid derivative mediates glycogen synthase kinase 3β to promote the porcine muscle satellite cell proliferation: Implications for cultured meat production.

  2024cites this paper
• Transformation of macrophages into myofibroblasts in fibrosis-related diseases: emerging biological concepts and potential mechanism

  2024cites this paper
• In Vitro Investigation of the Anti-Fibrotic Effects of 1-Phenyl-2-Pentanol, Identified from Moringa oleifera Lam., on Hepatic Stellate Cells

  2024cites this paper
• Quercetin inhibits chronic stress-mediated progression of triple-negative breast cancer by blocking β2-AR/ERK1/2 pathway.

  2024cites this paper
• Effects of Lithium Ions on tPA-Induced Hemorrhagic Transformation under Stroke

  2024cites this paper
• Potential Rheumatoid Arthritis-Associated Interstitial Lung Disease Treatment and Computational Approach for Future Drug Development

  2024cites this paper
• Study on the mechanism of herb cake-partitioned moxibustion inhibiting tumor growth in colitis-associated colorectal cancer based on KDM4D receptor

  2024cites this paper
• PAX1 represses canonical Wnt signaling pathway and plays dual roles during endoderm differentiation

  2024cites this paper
• Tanshinone IIA potentiates the chemotherapeutic effect of doxorubicin against breast cancer cells and attenuates the cardiotoxicity of doxorubicin by regulating ERK1/2 pathway

  2024cites this paper
• Targeting Wnt/β-catenin signaling and its interplay with TGF-β and Notch signaling pathways for the treatment of chronic wounds

  2024cites this paper
• Apoptosis Inhibitor 5: A Multifaceted Regulator of Cell Fate

  2024cites this paper
• NG2-Glia Cause Diabetic Blood-Brain Barrier Disruption by Secreting MMP-9

  2024cites this paper
• Wnt/β-catenin signaling in corneal epithelium development, homeostasis, and pathobiology.

  2024cites this paper
• Presence of Fusobacterium nucleatum in relation to patient survival and an acidic environment in oesophagogastric junction and gastric cancers

  2024cites this paper
• Mechanotransduction in tumor dynamics modeling.

  2023cites this paper
• Investigation of somatic mutation profiles and tumor evolution of primary oropharyngeal cancer and sequential lymph node metastases using multiregional whole‐exome sequencing

  2023cites this paper
• Dihydroartemisinin inhibits the development of colorectal cancer by GSK-3β/TCF7/MMP9 pathway and synergies with capecitabine.

  2023cites this paper
• Wnt/β-catenin signaling induces axial elasticity patterns of Hydra extracellular matrix

  2023cites this paper
• Redefining metalloproteases specificity through network proteolysis.

  2023cites this paper
• Mechanical effects modulate drug resistance in MCF-7-derived organoids: Insights into the wnt/β-catenin pathway.

  2023cites this paper
• WntA and Wnt4 during the regeneration of internal organs in the holothurian Eupentacta fraudatrix

  2023cites this paper
• Epidermal–dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures

  2023cites this paper
• Novel pharmacological approaches in abdominal aortic aneurysm

  2023cites this paper
• Research Progress in the Molecular Mechanisms, Therapeutic Targets, and Drug Development of Idiopathic Pulmonary Fibrosis

  2022cites this paper
• Fusobacterium nucleatum induces colon anastomosis leak by activating epithelial cells to express MMP9

  2022cites this paper
• Tumor Suppressor miRNA-503 Inhibits Cell Invasion in Head and Neck Cancer through the Wnt Signaling Pathway via the WNT3A/MMP Molecular Axis

  2022cites this paper
• Adipocyte-derived CCDC3 promotes tumorigenesis in epithelial ovarian cancer through the Wnt/ß-catenin signalling pathway

  2022cites this paper
• Pulmonary Fibrosis as a Result of Acute Lung Inflammation: Molecular Mechanisms, Relevant In Vivo Models, Prognostic and Therapeutic Approaches

  2022cites this paper
• Rho-GTPase dependent leukocyte interaction generates pro-inflammatory thymic Tregs and causes arthritis.

  2022cites this paper
• Transcription factor 4 expression and correlation with tumor progression in gallbladder cancer

  2022cites this paper
• Long non-coding RNA SNHG4 enhances RNF14 mRNA stability to promote the progression of colorectal cancer by recruiting TAF15 protein

  2022cites this paper
• Matrix Metalloproteinases and Their Inhibitors in Pulmonary Fibrosis: EMMPRIN/CD147 Comes into Play

  2022cites this paper
• miR-181-5p attenuates neutrophilic inflammation in asthma by targeting DEK.

  2022cites this paper
• Increase in ADAR1p110 activates the canonical Wnt signaling pathway associated with aggressive phenotype in triple negative breast cancer cells.

  2022cites this paper
• Design, synthesis and evaluation of 4,7-disubstituted 8-methoxyquinazoline derivatives as potential cytotoxic agents targeting β-catenin/TCF4 signaling pathway

  2022cites this paper
• Characterizing the extracellular matrix transcriptome of cervical, endometrial, and uterine cancers

  2022cites this paper
• In vitro modelling of human proprioceptive sensory neurons in the neuromuscular system

  2022cites this paper
• Lutein Treatment Effects on the Redox Status and Metalloproteinase-9 (MMP-9) in Oral Cancer Squamous Cells—Are There Therapeutical Hopes?

  2021cites this paper
• Targeting the Host Response: Can We Manipulate Extracellular Matrix Metalloproteinase Activity to Improve Influenza Virus Infection Outcomes?

  2021cites this paper
• Integrin α9 regulates smooth muscle cell phenotype switching and vascular remodeling

  2021influential citation
• Lipopolysaccharide endotoxin injections elevated salivary TNFα and corneal temperatures and induced dynamic changes in circulating leukocytes, inflammatory cytokines, and metabolic indicators in wether lambs.

  2021cites this paper
• Matrix metalloproteinases inhibitors in idiopathic pulmonary fibrosis: Medicinal chemistry perspectives.

  2021cites this paper
• DZIP1 regulates mammalian cardiac valve development through a Cby1‐β‐catenin mechanism

  2021cites this paper
• Immunological Insights in Equine Recurrent Uveitis

  2021cites this paper
• Osteoporosis and Osteoarthritis

  2021cites this paper
• Nuclear Dishevelled targets gene regulatory regions and promotes tumor growth

  2021cites this paper
• Quantitative Molecular Models for Biological Processes: Modeling of Signal Transduction Networks with ANIMO.

  2021cites this paper
• The role of renin angiotensin system in the pathophysiology of rheumatoid arthritis

  2021cites this paper
• Unspliced XBP1 Counteracts β-Catenin to Inhibit Vascular Calcification

  2021cites this paper
• Lgr4 Regulates Oviductal Epithelial Secretion Through the WNT Signaling Pathway

  2021cites this paper
• Type I Interferon Signaling Increases Versican Expression and Synthesis in Lung Stromal Cells During Influenza Infection

  2021cites this paper
• Netrin-like domain of sFRP4, a Wnt antagonist inhibits stemness, metastatic and invasive properties by specifically blocking MMP-2 in cancer stem cells from human glioma cell line U87MG.

  2021cites this paper
• Wnt Signalling in Regenerative Dentistry

  2021cites this paper
• Extracellular Matrix Enzymes and Immune Cell Biology

  2021cites this paper
• The Role of miRNA in the Pathophysiology of Neuroendocrine Tumors

  2021cites this paper
• Genome-wide DNA methylation pattern in systemic sclerosis microvascular endothelial cells: Identification of epigenetically affected key genes and pathways

  2021cites this paper
• Emodin suppresses the migration and invasion of melanoma cells.

  2021cites this paper
• Ubiquitin-Specific Proteases: Players in Cancer Cellular Processes

  2021cites this paper
• Arctigenin Suppressed Epithelial-Mesenchymal Transition Through Wnt3a/β-Catenin Pathway in PQ-Induced Pulmonary Fibrosis

  2020cites this paper
• Epithelial

  2020cites this paper
• Clinicopathological significance of intelectin‐1 in colorectal cancer: Intelectin‐1 participates in tumor suppression and favorable progress

  2020cites this paper
• Tanshinone II A improves the chemosensitivity of breast cancer cells to doxorubicin by inhibiting β‐catenin nuclear translocation

  2020cites this paper
• RETRACTED ARTICLE: Upregulation of ARHGAP30 attenuates pancreatic cancer progression by inactivating the β-catenin pathway

  2020cites this paper
• WNT7A Expression is Downregulated in T Lymphocytes after T-Cell Receptor Activation Due to Histone Modifications and in T-ALL by DNA Methylation

  2020cites this paper
• Cell to cell communication is an early event in glioblastoma

  2020cites this paper
• HLY78 protects blood-brain barrier integrity through Wnt/β-catenin signaling pathway following subarachnoid hemorrhage in rats.

  2020cites this paper
• GSK3 modulation in acute lung injury, myocarditis and polycystic kidney disease-related aneurysm

  2020cites this paper
• TNFα/Grnd mediate JNK/MMPs activation during glioma progression and neurodegeneration

  2020cites this paper
• Role of Sirtuins in Tumor Angiogenesis

  2020cites this paper
• A Penicillin Derivative Exerts an Anti-Metastatic Activity in Melanoma Cells Through the Downregulation of Integrin αvβ3 and Wnt/β-Catenin Pathway

  2020cites this paper
• Dysbiosis in Peripheral Blood Mononuclear Cell Virome Associated With Systemic Lupus Erythematosus

  2020cites this paper
• Smooth-muscle-derived WNT5A augments allergen-induced airway remodelling and Th2 type inflammation

  2020cites this paper
• LncRNA ANRIL/miR-7-5p/TCF4 axis contributes to the progression of T cell acute lymphoblastic leukemia

  2020cites this paper
• Attenuation of Wnt/β-catenin signaling in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis

  2020cites this paper
• Low‐temperature plasma‐activated medium inhibited invasion and metastasis of melanoma cells via suppressing the Wnt/β‐catenin pathway

  2019cites this paper
• Matrix metalloproteinase: An upcoming therapeutic approach for idiopathic pulmonary fibrosis.

  2019cites this paper
• Glioblastoma cells vampirize WNT from neurons and trigger a JNK/MMP signaling loop that enhances glioblastoma progression and neurodegeneration

  2019cites this paper
• Wnt/β-catenin signalling in ovarian cancer: Insights into its hyperactivation and function in tumorigenesis

  2019cites this paper
• Regulatory T Cells Induce Metastasis by Activating Tgf-Β and Enhancing the Epithelial–Mesenchymal Transition

  2019cites this paper
• Wingless promotes JNK/MMPs positive feedback loop mediate tumour microtubes expansion, glioma progression and neurodegeneration

  2019cites this paper
• Protection of blood-brain barrier as a potential mechanism for enriched environments to improve cognitive impairment caused by chronic cerebral hypoperfusion.

  2019cites this paper
• Measuring Serum Sclerostin in Egyptian Patients With Systemic Lupus Erythematosus and Evaluating Its Effect on Disease Activity: A Case-Control Study.

  2019cites this paper
• Protective effects of febuxostat against paraquat‐induced lung toxicity in rats: Impact on RAGE/PI3K/Akt pathway and downstream inflammatory cascades

  2019cites this paper
• Novel Approaches for Extracellular Matrix Targeting in Disease Treatment.

  2019cites this paper
• Rapalog resistance is associated with mesenchymal-type changes in Tsc2-null cells

  2019cites this paper
• Quercetin improves blood-brain barrier dysfunction in rats with cerebral ischemia reperfusion via Wnt signaling pathway.

  2019cites this paper
• Postmortem vs. neoplastic gene expression: Clues to cancer development and therapy.

  2019cites this paper
• Oncolytic Ad co-expressing decorin and Wnt decoy receptor overcomes chemoresistance of desmoplastic tumor through degradation of ECM and inhibition of EMT.

  2019cites this paper