CAMTA1, a 1p36 tumor suppressor candidate, inhibits growth and activates differentiation programs in neuroblastoma cells.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Cancer Research

• Publication date

  2011-04-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1158/0008-5472.CAN-10-3014PMID 21385898
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• [Oncogene].

  2019cited by this paper
• Handbook of statistics in clinical oncology

  2013cited by this paper
• Transcriptional repression of SKP2 is impaired in MYCN-amplified neuroblastoma.

  2010cited by this paper
• Predicting outcomes for children with neuroblastoma using a multigene-expression signature: a retrospective SIOPEN/COG/GPOH study.

  2009cited by this paper
• High-throughput detection and multiplex identification of cell contaminations

  2009cited by this paper
• Anti-neuroblastoma activity of Helminthosporium carbonum (HC)-toxin is superior to that of other differentiating compounds in vitro.

  2008cited by this paper
• Histone deacetylase inhibitors: apoptotic effects and clinical implications (Review).

  2008cited by this paper
• 1p36 is a preferential target of chromosome 1 deletions in astrocytic tumours and homozygously deleted in a subset of glioblastomas

  2008cited by this paper
• Histone deacetylase inhibitor Helminthosporium carbonum (HC)‐toxin suppresses the malignant phenotype of neuroblastoma cells

  2007cited by this paper
• CAMTAs: Calmodulin‐binding transcription activators from plants to human

  2007cited by this paper
• Allelic variants of CAMTA1 and FLJ10737 within a commonly deleted region at 1p36 in neuroblastoma.

  2007influential reference
• Cross-study analysis of gene expression data for intermediate neuroblastoma identifies two biological subtypes

  2007cited by this paper
• CHD5 is a tumor suppressor at human 1p36.

  2007cited by this paper
• Customized oligonucleotide microarray gene expression-based classification of neuroblastoma patients outperforms current clinical risk stratification.

  2006influential reference
• Recurrent genomic alterations with impact on survival in colorectal cancer identified by genome-wide array comparative genomic hybridization.

  2006cited by this paper
• Differential Expression of Neuronal Genes Defines Subtypes of Disseminated Neuroblastoma with Favorable and Unfavorable Outcome

  2006cited by this paper
• Reduced Expression of CAMTA1 Correlates with Adverse Outcome in Neuroblastoma Patients

  2006influential reference
• Prognostic significance of gene expression profiles of metastatic neuroblastomas lacking MYCN gene amplification.

  2006cited by this paper
• Molecular and Developmental Biology of Neuroblastoma

  2005cited by this paper
• Differential expression with the Bioconductor Project

  2005cited by this paper
• Definition and characterization of a region of 1p36.3 consistently deleted in neuroblastoma

  2005cited by this paper
• Prognostic Factor Studies

  2005cited by this paper
• Allelic losses at 1p36 and 19q13 in gliomas: correlation with histologic classification, definition of a 150-kb minimal deleted region on 1p36, and evaluation of CAMTA1 as a candidate tumor suppressor gene.

  2005cited by this paper
• Cell cycle-dependent transcriptional regulation of calmodulin-binding transcription activator 1 in neuroblastoma cells.

  2004cited by this paper
• Confidence intervals for the effect of a prognostic factor after selection of an ‘optimal’ cutpoint

  2004cited by this paper
• Expression with the Bioconductor Project

  2004cited by this paper
• GOTree Machine (GOTM): a web-based platform for interpreting sets of interesting genes using Gene Ontology hierarchies

  2004cited by this paper
• Expression profiling and characterization of 4200 genes cloned from primary neuroblastomas: identification of 305 genes differentially expressed between favorable and unfavorable subsets

  2003cited by this paper
• A Novel Family of Calmodulin-binding Transcription Activators in Multicellular Organisms*

  2002cited by this paper
• Smallest region of overlapping deletion in 1p36 in human neuroblastoma: A 1 Mbp cosmid and PAC contig

  2001cited by this paper
• Loss of heterozygosity at 1p36 independently predicts for disease progression but not decreased overall survival probability in neuroblastoma patients: a Children's Cancer Group study.

  2000cited by this paper
• Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid. Children's Cancer Group.

  1999cited by this paper
• Flow cytometric DNA analysis and chromosomal aberrations in malignant glioblastomas.

  1999cited by this paper
• Treatment of High-Risk Neuroblastoma with Intensive Chemotherapy, Radiotherapy, Autologous Bone Marrow Transplantation, and 13-cis-Retinoic Acid

  1999cited by this paper
• Induction of axon-like and dendrite-like processes in neuroblastoma cells

  1998cited by this paper
• Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

  1998cited by this paper
• Sodium valproate inhibits in vivo growth of human neuroblastoma cells.

  1997cited by this paper
• Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.

  1996cited by this paper
• Maximally selected rank statistics

  1992cited by this paper

• Methylome analysis of FTLD patients with TDP-43 pathology identifies epigenetic signatures specific to pathological subtypes

  2025cites this paper
• Mediating role of whole epigenome DNA methylation signatures in the association between copper and SGA.

  2025cites this paper
• Predicting somatic mutation origins in cell-free DNA by semi-supervised GAN models

  2024cites this paper
• [MiR-132-3p negatively regulates CAMTA1 to promote Schwann cell proliferation and migration and alleviates I-125 seeds-induced exacerbation of facial nerve injury in rats].

  2024cites this paper
• Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing associated with therapeutic response to splicing inhibitor

  2024cites this paper
• Collateral lethality: A unique type of synthetic lethality in cancers.

  2024cites this paper
• Linking Gene Fusions to Bone Marrow Failure and Malignant Transformation in Dyskeratosis Congenita

  2024cites this paper
• Single-cell multiome sequencing clarifies enteric glial diversity and identifies an intraganglionic population poised for neurogenesis

  2023cites this paper
• CAMTA1‐related disorder: Phenotypic and molecular characterization of 26 new individuals and literature review

  2023cites this paper
• Metabolic reprogramming of cancer cells by JMJD 6-mediated pre-mRNA splicing is associated 1 with therapeutic response to splicing inhibitor 2 3

  2023cites this paper
• A single nuclei atlas of aging human abdominal subcutaneous white adipose tissue

  2023cites this paper
• Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing is associated with therapeutic response to splicing inhibitor

  2023cites this paper
• Current Model Systems for Investigating Epithelioid Haemangioendothelioma

  2023cites this paper
• Allele-specific expression reveals genes with recurrent cis-regulatory alterations in high-risk neuroblastoma

  2022cites this paper
• The TAZ-CAMTA1 Fusion Protein Promotes Tumorigenesis via Connective Tissue Growth Factor and Ras–MAPK Signaling in Epithelioid Hemangioendothelioma

  2022cites this paper
• The role of Calmodulin Binding Transcription Activator 1 (CAMTA1) gene and its putative genetic partners in the human nervous system

  2022cites this paper
• Single-nucleus chromatin accessibility and RNA sequencing reveal impaired brain development in prenatally e-cigarette exposed neonatal rats

  2022cites this paper
• Unraveling the Biology of Epithelioid Hemangioendothelioma, a TAZ–CAMTA1 Fusion Driven Sarcoma

  2022cites this paper
• Abnormally increased DNA methylation in chorionic tissue might play an important role in development of ectopic pregnancy

  2021cites this paper
• Research Progress on Regulating LncRNAs of Hepatocellular Carcinoma Stem Cells

  2021cites this paper
• Copy Number Alterations in Hepatoblastoma: Literature Review and a Brazilian Cohort Analysis Highlight New Biological Pathways

  2021cites this paper
• OTT_A_289064 917..927

  2021cites this paper
• Allele-specific expression links diverse cis-regulatory mutations to recurrent gene dysregulation in high-risk neuroblastoma

  2021cites this paper
• Epigenetic regulation of DAT gene promoter modulates the risk of Externalizing and Internalizing behaviors on a normative population: an explorative study.

  2021cites this paper
• Hypoxia Predicts Poor Prognosis in Neuroblastoma Patients and Associates with Biological Mechanisms Involved in Telomerase Activation and Tumor Microenvironment Reprogramming

  2020cites this paper
• DNA methylation of the 5'-UTR DAT 1 gene in Parkinson's disease patients.

  2020cites this paper
• Super enhancers define regulatory subtypes and cell identity in neuroblastoma

  2020cites this paper
• Expanding the molecular spectrum and the neurological phenotype related to CAMTA1 variants

  2020cites this paper
• Sex-Specific Transcriptome Differences in Human Adipose Mesenchymal Stem Cells

  2020cites this paper
• Role of Genetic and Epigenetic Alterations in Pathogenesis of Neuroblastoma

  2019cites this paper
• Genome-wide association study and a post replication analysis revealed a promising genomic region and candidate genes for chicken eggshell blueness

  2019cites this paper
• LINC01355 suppresses breast cancer growth through FOXO3-mediated transcriptional repression of CCND1

  2019cites this paper
• Integrative Omic Analysis of Neuroblastoma

  2019cites this paper
• Effect of ghost pepper on cell proliferation, apoptosis, senescence and global proteomic profile in human renal adenocarcinoma cells

  2018cites this paper
• Proteomic Dissection of Nanotopography-Sensitive Mechanotransductive Signaling Hubs that Foster Neuronal Differentiation in PC12 Cells

  2018influential citation
• Epithelioid Hemangioendothelioma as a Model of YAP/TAZ-Driven Cancer: Insights from a Rare Fusion Sarcoma

  2018cites this paper
• Oncogenic ALK signaling in neuroblastoma

  2017cites this paper
• Platelet-targeted pharmacologic treatments as anti-cancer therapy

  2017cites this paper
• The role of KIF1Bß in neuroblastoma tumour suppression during sympathetic neuron development

  2017cites this paper
• A Novel Combination Therapy of Cisplatin with a Molecular Promoter for Cancer Treatment

  2017cites this paper
• MiRNA-124-3p Reduces Cell Viability in Cisplatin Resistant Neuroblastoma Cell Models.

  2017influential citation
• Molecular Genetics of Neuroblastoma

  2017cites this paper
• Heparin‐binding epidermal growth factor‐like growth factor promotes neuroblastoma differentiation

  2017influential citation
• Long Noncoding RNA lncCAMTA1 Promotes Proliferation and Cancer Stem Cell-Like Properties of Liver Cancer by Inhibiting CAMTA1

  2016cites this paper
• Mechanism of action of a WWTR1(TAZ)-CAMTA1 fusion oncoprotein

  2016cites this paper
• Neuroblastoma: A Tough Nut to Crack.

  2016cites this paper
• microRNAs Regulate Host Immune Response and Pathogenesis During Influenza Infection in Rhesus Macaques

  2016cites this paper
• Neuroblastoma patient outcomes, tumor differentiation, and ERK activation are correlated with expression levels of the ubiquitin ligase UBE4B

  2016cites this paper
• Integrator of Stress Responses Calmodulin Binding Transcription Activator 1 (Camta1) Regulates miR-212/miR-132 Expression and Insulin Secretion*

  2016cites this paper
• Antitumor effect of antiplatelet agents in gastric cancer cells: an in vivo and in vitro study

  2016cites this paper
• miR-20b Inhibits T Cell Proliferation and Activation via NFAT Signaling Pathway in Thymoma-Associated Myasthenia Gravis

  2016cites this paper
• Unveiling MYCN regulatory networks in neuroblastoma via integrative analysis of heterogeneous genomics data

  2016cites this paper
• Research progress of neuroblastoma related gene variations

  2016cites this paper
• A recellularized human colon model identifies cancer driver genes

  2016cites this paper
• Integrative Genome-Scale Analysis Identifies Epigenetic Mechanisms of Transcriptional Deregulation in Unfavorable Neuroblastomas.

  2016cites this paper
• Characterization of CAMTA1 and Nkx2.2 in the context of glioblastoma cancer stem cell biology

  2016influential citation
• The calmodulin-binding transcription activator CAMTA1 is required for long-term memory formation in mice

  2016cites this paper
• Transcriptome Profiling Reveals Disruption of Innate Immunity in Chronic Heavy Ethanol Consuming Female Rhesus Macaques

  2016cites this paper
• The Role of Stromal-Derived Factors in Neuroblastoma Differentiation

  2016cites this paper
• Importance of rare gene copy number alterations for personalized tumor characterization and survival analysis

  2016cites this paper
• Collateral Lethality: A new therapeutic strategy in oncology.

  2015cites this paper
• Mechanistic Implications and Characterization of Anaplastic Lymphoma Kinase (ALK) mutations in Neuroblastoma

  2015cites this paper
• Intragenic CAMTA1 deletions are associated with a spectrum of neurobehavioral phenotypes

  2015cites this paper
• DNA Copy Number Changes and Beyond

  2015cites this paper
• Identification of long non-coding RNAs that regulate apoptosis in human

  2015cites this paper
• Pancreatic Cancer Patient Survival Correlates with DNA Methylation of Pancreas Development Genes

  2015cites this paper
• p19-INK4d inhibits neuroblastoma cell growth, induces differentiation and is hypermethylated and downregulated in MYCN-amplified neuroblastomas.

  2014influential citation
• Ataxia and Purkinje cell degeneration in mice lacking the CAMTA1 transcription factor

  2014cites this paper
• Therapeutic targets for neuroblastomas

  2014cites this paper
• Neuropsychological and neuroimaging phenotype induced by a CAMTA1 mutation.

  2014cites this paper
• UBE4B levels are correlated with clinical outcomes in neuroblastoma patients and with altered neuroblastoma cell proliferation and sensitivity to epidermal growth factor receptor inhibitors

  2013cites this paper
• Analisis de la expresión y la función del receptor sensor de calcio en tumores del desarrollo

  2013cites this paper
• Low p14ARF expression in neuroblastoma cells is associated with repressed histone mark status, and enforced expression induces growth arrest and apoptosis.

  2013cites this paper
• CDK4 inhibition restores G₁-S arrest in MYCN-amplified neuroblastoma cells in the context of doxorubicin-induced DNA damage

  2013cites this paper
• The calcium-sensing receptor is silenced by genetic and epigenetic mechanisms in unfavorable neuroblastomas and its reactivation induces ERK1/2-dependent apoptosis

  2013cites this paper
• Genetic Instability and Intratumoral Heterogeneity in Neuroblastoma with MYCN Amplification Plus 11q Deletion

  2013cites this paper
• Molecular diagnostics complementing morphology in superficial mesenchymal tumors.

  2013cites this paper
• MicroRNA-124 Suppresses the Transactivation of Nuclear Factor of Activated T Cells by Targeting Multiple Genes and Inhibits the Proliferation of Pulmonary Artery Smooth Muscle Cells*

  2013cites this paper
• The role of genetic and epigenetic alterations in neuroblastoma disease pathogenesis

  2013cites this paper
• A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival.

  2013cites this paper
• Children's Oncology Group's 2013 blueprint for research: Neuroblastoma

  2013cites this paper
• Low p 14 ARF expression in neuroblastoma cells is associated with repressed histone mark status , and enforced expression induces growth arrest and apoptosis

  2013cites this paper
• Passenger Deletions Generate Therapeutic Vulnerabilities in Cancer

  2012cites this paper
• 1p36 tumor suppression--a matter of dosage?

  2012influential citation
• New prognostic markers in neuroblastoma.

  2012cites this paper
• The role of molecular testing in the diagnosis of cutaneous soft tissue tumors.

  2012cites this paper
• Anaplastic Lymphoma Kinase mutations and downstream signalling

  2012cites this paper
• The calcium-sensing receptor is silenced by genetic and epigenetic mechanisms in unfavorable neuroblastomas and its reactivation induces ERK1/2-dependent apoptosis.

  2012cites this paper
• A Matter of Dosage ? − − 1 p 36 Tumor Suppression

  2012influential citation
• Calcium Dependent CAMTA1 in Adult Stem Cell Commitment to a Myocardial Lineage

  2012cites this paper
• Intragenic CAMTA1 rearrangements cause non-progressive congenital ataxia with or without intellectual disability

  2012cites this paper
• Tumor Suppression — A Matter of Dosage ?

  2012influential citation
• Biomarqueurs d'inactivation de gène collatérale et cibles pour une thérapie anticancéreuse

  2012cites this paper
• CAMTA 1 is a novel tumour suppressor regulated by miR-9 / 9 * in glioblastoma stem cells

  2011cites this paper
• Refinement of 1p36 Alterations Not Involving PRDM16 in Myeloid and Lymphoid Malignancies

  2011cites this paper
• CAMTA1 is a novel tumour suppressor regulated by miR‐9/9* in glioblastoma stem cells

  2011cites this paper
• Monosomal complex karyotype in pediatric mixed phenotype acute leukemia.

  2011cites this paper
• Genetic stratification of neuroblastoma for treatment tailoring.

  2011cites this paper
• Neuroblastoma genetics and phenotype: a tale of heterogeneity.

  2011cites this paper