Increased uptake of fatty acids by the isolated rat liver after raising the fatty acid binding protein concentration with clofibrate.

No abstract is available for this paper.

• Publication year

  1978

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  1978-01-30

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/0006-291X(78)90680-0PMID 623666
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Effect of clofibrate administration on several biochemical parameters of normal and thyroidectomized rats.

  1977cited by this paper
• Reduced concentrations of Z protein in Morris hepatomas. Possible role in abnormal regulation of lipid metabolism.

  1977cited by this paper
• Increase in the hepatic glucuronidation and clearance of bilirubin in clofibrate-treated rats.

  1977cited by this paper
• Reversal of orotic acid-induced fatty liver in rats by clofibrate.

  1977cited by this paper
• A fatty acyl-CoA oxidizing system in rat liver peroxisomes; enhancement by clofibrate, a hypolipidemic drug.

  1976cited by this paper
• Fatty acid binding protein. Role in esterification of absorbed long chain fatty acid in rat intestine.

  1976cited by this paper
• The role of fatty acid binding protein on the metabolism of fatty acids in isolated rat hepatocytes.

  1976cited by this paper
• Z protein in hepatic uptake and esterification of long-chain fatty acids.

  1975cited by this paper
• Stimulation of monoacylglycerophosphate formation

  1974cited by this paper
• Stimulation of monoacylglycerophosphate formation by Z protein.

  1974cited by this paper
• The binding of long chain fatty acid CoA to Z, a cytoplasmic protein present in liver and other tissues of the rat.

  1974cited by this paper
• Lipid metabolism of rat liver isolated and perfused in hypoxia.

  1974cited by this paper
• Fatty acid-binding protein in small intestine. Identification, isolation, and evidence for its role in cellular fatty acid transport.

  1974cited by this paper
• Study of Y and Z, two cytoplasmic bilirubin binding proteins. Their development in the liver of foetal and newborn Wistar and Gunn rats.

  1973cited by this paper
• Influence of chain length and degree of unsaturation on plasma free fatty acid uptake by the perfused rat liver.

  1973cited by this paper
• A Binding Protein for Fatty Acids in Cytosol of Intestinal Mucosa, Liver, Myocardium, and Other Tissues

  1972cited by this paper
• The binding of fatty acids to cytoplasmic proteins: binding to Z protein in liver and other tissues of the rat.

  1972cited by this paper
• Analysis of ribosomes and polysomes derived from rabbit mammary glands during pregnancy and lactation.

  1971cited by this paper
• Phenobarbital-induced alterations in phosphatidylcholine and triglyceride synthesis in hepatic endoplasmic reticulum.

  1971cited by this paper
• A modified method for the isolation of the plasma membrane from rat liver.

  1970cited by this paper
• Effects of chlorophenoxyisobutyrate (CPIB) on liver composition and triglyceride synthesis in rats

  1966cited by this paper
• Titration of free fatty acids of plasma: a study of current methods and a new modification.

  1960cited by this paper
• A simple method for the isolation and purification of total lipides from animal tissues.

  1957cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper
• A revision of the Schoenheimer-Sperry method for cholesterol determination.

  1950cited by this paper
• THE COLORIMETRIC DETERMINATION OF PHOSPHORUS

  1925cited by this paper

• Stearic acid induces proinflammatory cytokine production partly through activation of lactate-HIF1α pathway in chondrocytes

  2015cites this paper
• A novel prodrug strategy for extremely hydrophobic agents: conjugation to symmetrically branched glycerol trimer improves pharmacological and pharmacokinetic properties of fenofibrate.

  2013cites this paper
• Isolation and characterization of binder IIIA, a new protein which binds corticosteroid anions.

  2005cites this paper
• Effects of linoleic and gamma-linolenic acids (efamol evening primrose oil) on fatty acid-binding proteins of rat liver

  2004influential citation
• Cytosolic fatty acid binding proteins catalyze two distinct steps in intracellular transport of their ligands

  2002cites this paper
• Induction of hepatic cytosolic fatty acid binding protein with clofibrate accelerates both membrane and cytoplasmic transport of palmitate.

  2000cites this paper
• Characterisation of monolysocardiolipin acyltransferase activity

  2000cites this paper
• Cytosolic fatty acid binding protein enhances rat hepatocyte [3H]palmitate uptake.

  1999cites this paper
• Hepatic VLDL secretion of genetically obese Zucker rats is inhibited by a high-fat diet.

  1996cites this paper
• Inhibition of hepatic very-low-density lipoprotein secretion in obese Zucker rats adapted to a high-protein diet.

  1995cites this paper
• Effects of microsomal enzyme inducers on glutathione S-transferase isoenzymes in livers of rats and hamsters.

  1994cites this paper
• Transport of organic anions in the liver. An update on bile acid, fatty acid, monocarboxylate, anionic amino acid, cholephilic organic anion, and anionic drug transport.

  1994cites this paper
• Fatty‐acid metabolism and the pathogenesis of hepatocellular carcinoma: Review and hypothesis

  1993cites this paper
• Dietary clofibric acid increases intestinal fatty acid binding protein activity and apparent lipid digestibility in weanling swine.

  1993cites this paper
• Endocytic Components: Identification and Characterization

  1993cites this paper
• The endocytic compartments of normal and regenerating liver.

  1993cites this paper
• Rat brain fatty acid-binding protein during development.

  1992cites this paper
• Structural and functional features of different types of cytoplasmic fatty acid-binding proteins.

  1991cites this paper
• In situ binding of fatty acids to the liver fatty acid binding protein: analysis using 3-[125I]iodo-4-azido-N-hexadecylsalicylamide.

  1991cites this paper
• Interaction of LY171883 and other peroxisome proliferators with fatty-acid-binding protein isolated from rat liver.

  1991cites this paper
• Functions of fatty acid binding proteins

  1990cites this paper
• Intracellular fatty-acid-binding proteins. Characteristics and function.

  1990cites this paper
• Effects of dietary corn oil and salmon oil on the oxidation of fatty acids and prostaglandin E2 in rat gastric mucosa.

  1989cites this paper
• The hepatocellular transport of sulfobromophthalein-glutathione by clofibrate treated, perfused rat liver

  1989cites this paper
• Intracellular fatty acid trafficking and the role of cytosolic lipid binding proteins.

  1989cites this paper
• Mechanism of hepatic fatty acid uptake.

  1989cites this paper
• A relationship between retinol and cellular retinol-binding protein concentrations in human squamous cell carcinomas.

  1989cites this paper
• Effects of ciprofibrate and 2-[5-(4-chlorophenyl)pentyl]oxirane-2-carboxylate (POCA) on the distribution of carnitine and CoA and their acyl-esters and on enzyme activities in rats. Relation between hepatic carnitine concentration and carnitine acetyltransferase activity.

  1988cites this paper
• Choline-deficient diet increases Z protein concentration in rat liver.

  1988cites this paper
• Pharmacokinetics and enterohepatic circulation of 2-n-propyl-4-pentenoic acid in the rat.

  1988cites this paper
• The cellular fatty acid binding proteins: aspects of structure, regulation, and function.

  1988cites this paper
• Studies on sterol carrier protein

  1988cites this paper
• Sex differences in membrane potential in the intact perfused rat liver.

  1988cites this paper
• Influence of genetic obesity and of fat-feeding on hepatic FABP concentration and activity.

  1988cites this paper
• Metabolic fate of arachidonic acid in hepatocytes of continuously endotoxemic rats.

  1988cites this paper
• The metabolic significance of mammalian fatty-acid-binding proteins: abundant proteins in search of a function.

  1987cites this paper
• Studies on fatty acid-binding proteins. The diurnal variation shown by rat liver fatty acid-binding protein.

  1987cites this paper
• Sterol carrier and lipid transfer proteins.

  1987cites this paper
• THE METABOLIC SIGNIFICANCE OF MAMMALIAN FATTY-ACID­

  1987cites this paper
• TRANSPORT IN EUKARYOTES

  1987cites this paper
• Analysis of the tissue-specific expression, developmental regulation, and linkage relationships of a rodent gene encoding heart fatty acid binding protein.

  1987cites this paper
• Interaction of Lipid-Lowering Drugs with Fatty Acid-Binding Proteins

  1987cites this paper
• Organic aciduria in rats made resistant to hypoglycin toxicity by pretreatment with clofibrate.

  1987cites this paper
• Effect of liver fatty acid binding protein on fatty acid movement between liposomes and rat liver microsomes.

  1987cites this paper
• Intracellular lipid transport in eukaryotes.

  1987cites this paper
• Hepatocellular uptake of organic anions.

  1986cites this paper
• Selective inhibition of long-chain fatty acid uptake in short-term cultured rat hepatocytes by an antibody to the rat liver plasma membrane fatty acid-binding protein.

  1986cites this paper
• The nucleotide sequence of the rat liver fatty acid-binding protein gene. Evidence that exon 1 encodes an oligopeptide domain shared by a family of proteins which bind hydrophobic ligands.

  1986cites this paper
• Hepatocellular influx of [14C]oleate reflects membrane transport rather than intracellular metabolism or binding.

  1986cites this paper
• Studies on fatty acid-binding proteins. The detection and quantification of the protein from rat liver by using a fluorescent fatty acid analogue.

  1986cites this paper
• Studies on Hepatocellular Uptake of Fatty Acids

  1986cites this paper
• Fatty acid-binding capacity of cytosolic proteins of various rat tissues: effect of postnatal development, starvation, sex, clofibrate feeding and light cycle.

  1986cites this paper
• Hepatocellular uptake of oleate is energy dependent, sodium linked, and inhibited by an antibody to a hepatocyte plasma membrane fatty acid binding protein.

  1986cites this paper
• A protein of the Z class of liver cytosolic proteins in the rat that preferentially binds heme.

  1985cites this paper
• Dietary and nutritional aspects of fatty acid binding proteins.

  1985cites this paper
• Concomitant increase by peroxisome proliferators of fatty acid-binding protein, peroxisomal beta-oxidation and cytosolic acyl-CoA hydrolase in liver.

  1985cites this paper
• Tissue specific expression and developmental regulation of two genes coding for rat fatty acid binding proteins.

  1985cites this paper
• Turnover and short-term regulation of fatty acid binding protein in liver.

  1985cites this paper
• Chapter 2 Control mechanisms in sterol uptake and biosynthesis

  1985cites this paper
• Regulation of the biosynthesis of two distinct fatty acid-binding proteins in rat liver and intestine. Influences of sex difference and of clofibrate.

  1985cites this paper
• Protection of rats by clofibrate against the hypoglycaemic and toxic effects of hypoglycin and pent-4-enoate. An ultrastructural and biochemical study.

  1985cites this paper
• Role of sterol carrier protein in cholesterol metabolism.

  1985cites this paper
• Function and regulation of hepatic and intestinal fatty acid binding proteins.

  1985cites this paper
• Intracellular fatty acid-binding proteins.

  1985cites this paper
• Free fatty-acid uptake by isolated rat hepatocytes.

  1985cites this paper
• Analyzing the structures, functions and evolution of two abundant gastrointestinal fatty acid binding proteins with recombinant DNA and computational techniques.

  1985cites this paper
• Diurnal variation of cytosolic fatty acid-binding protein content and of palmitate oxidation in rat liver and heart.

  1984cites this paper
• Mechanisms of bile formation, hepatic uptake, and biliary excretion.

  1984cites this paper
• Regulation of lipid metabolism by a lipid-carrying protein.

  1984cites this paper
• Expression of a mammalian fatty acid-binding protein in Escherichia coli.

  1984cites this paper
• Glucuronidation and elimination of diflunisal in the isolated perfused rat liver: effect of pretreatment with phenobarbitone, clofibric acid and spironolactone.

  1984cites this paper
• Concomitant increase in hepatic triacylglycerol biosynthesis and cytosolic fatty-acid-binding-protein content after feeding rats with a cholestyramine-containing diet.

  1983cites this paper
• Effects of peroxisome proliferators on fatty acid-binding protein in rat liver.

  1983cites this paper
• Effect of clofibrate on the metabolism of oleate in the perfused rat liver.

  1983cites this paper
• Cytosolic modulators of activities of microsomal enzymes of cholesterol biosynthesis. Effects of Acyl-CoA inhibition and cytosolic Z-protein.

  1983cites this paper
• Carnitine--metabolism and functions.

  1983cites this paper
• Quantitation of hepatic fatty acid-binding proteins by post-chromatographic ligand binding assay.

  1983cites this paper
• Stimulation of fatty acid utilization by sodium clofibrate in rat and monkey hepatocytes.

  1983cites this paper
• The nucleotide sequence of rat liver fatty acid binding protein mRNA.

  1983cites this paper
• 15 – The Regulation of Long Chain Fatty Acid Oxidation

  1983cites this paper
• Liver cytosolic fatty acid-binding proteins. Effect of diabetes and starvation.

  1983cites this paper
• The role of albumin in hepatic uptake processes.

  1982cites this paper
• [Polypeptide spectra of subcellular fractions of hepatocytes isolated from normal rats and from rats treated with clofibrate].

  1982cites this paper
• [Endogenous lipid pattern, organ distribution and effect of diet on a fatty acid binding protein fraction of rat liver cytosol].

  1982cites this paper
• Fatty acid binding protein. Isolation from rat liver, characterization, and immunochemical quantification.

  1982cites this paper
• Effects of some hypolipidemic drugs and phthalic acid esters on fatty acid binding protein in rat liver.

  1982cites this paper
• Membrane traffic at the hepatocyte's sinusoidal and canalicular surface domains

  1981cites this paper
• Changes in peroxisomal fatty acid oxidation in the diabetic rat liver.

  1981cites this paper
• Possible involvement of fatty acid binding protein in peroxisomal beta-oxidation of fatty acids.

  1980cites this paper
• A biochemical dissection of the functional polarity of the plasma membrane of the hepatocyte.

  1980cites this paper
• A biochemical dissection of the functional polarity of the plasma membrane of the hepatocyte

  1980cites this paper
• Possible involvement of fatty acid binding protein in peroxisomal β-oxidation of fatty acids

  1980cites this paper
• Glycogenolytic and hypolipidemic effect of clofibrate (CPIB) in the hypothyroid chick.

  1980cites this paper
• Effect of clofibrate on the enzyme activity of rat liver plasma membranes

  1980cites this paper
• Mitochondrial and peroxisomal fatty acid oxidation in liver homogenates and isolated hepatocytes from control and clofibrate-treated rats.

  1979cites this paper
• Effect of clofibrate on the CoA thioester profile in rat liver.

  1979cites this paper
• Protection of rats against hypoglycin and pent-4-enoate toxicity by pretreatment with clofibrate [proceedings].

  1979cites this paper
• Regulation of palmitoyl-CoA inhibition of mitochondrial adenine nucleotide transport by cytosolic fatty acid binding protein.

  1979cites this paper
• [Induction of fatty acid oxidation in peroxisomes of rat liver by magnesium-4 chlorophenoxyisobutyrate (Mg-CPIB)].

  1979cites this paper
• Utilization of long chain fatty acids by rat liver: studies of the role of fatty acid binding protein.

  1979cites this paper