Trauma-induced coagulopathy

No abstract is available for this paper.

• Publication year

  2021

• Venue

  Nature Reviews Disease Primers

• Publication date

  2021-04-29

• Fields of study

  Medicine

• Identifiers
  DOI 10.1038/s41572-021-00270-5PMID 33927205
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The S100A10 Pathway Mediates an Occult Hyperfibrinolytic Subtype in Trauma Patients.

  2019cited by this paper
• The European guideline on management of major bleeding and coagulopathy following trauma: fifth edition

  2019cited by this paper
• Trauma-induced coagulopathy upon emergency room arrival: still a significant problem despite increased awareness and management?

  2019cited by this paper
• Trauma‐induced coagulopathy: The past, present, and future

  2019cited by this paper
• Trauma-induced coagulopathy. A narrative review of goal-directed hemostatic resuscitation

  2018cited by this paper
• Hemostatic Management of Trauma‐Induced Coagulopathy

  2017cited by this paper
• Damage control resuscitation: a practical approach for severely hemorrhagic patients and its effects on trauma surgery

  2017cited by this paper
• The impact of early thromboelastography directed therapy in trauma resuscitation

  2017cited by this paper
• Goal-directed Hemostatic Resuscitation of Trauma-induced Coagulopathy: A Pragmatic Randomized Clinical Trial Comparing a Viscoelastic Assay to Conventional Coagulation Assays

  2016cited by this paper
• Triad of death: the importance of temperature monitoring in trauma patients.

  2016cited by this paper
• Viscoelastic Methods of Blood Clotting Assessment – A Multidisciplinary Review

  2015cited by this paper
• An International Normalized Ratio–Based Definition of Acute Traumatic Coagulopathy Is Associated With Mortality, Venous Thromboembolism, and Multiple Organ Failure After Injury

  2015cited by this paper
• Recent Advances of Hemorrhage Management in Severe Trauma

  2014cited by this paper
• An Update on the Coagulopathy of Trauma

  2014influential reference
• Fibrinogen and platelet contributions to clot formation: Implications for trauma resuscitation and thromboprophylaxis

  2014cited by this paper
• Gerinnungsmanagement beim Polytrauma

  2014cited by this paper
• Elevated Tissue Plasminogen Activator and Reduced Plasminogen Activator Inhibitor Promote Hyperfibrinolysis in Trauma Patients

  2014cited by this paper
• Fibrinolysis greater than 3% is the critical value for initiation of antifibrinolytic therapy

  2013cited by this paper
• Treatment of Acute Coagulopathy Associated with Trauma

  2013cited by this paper
• Fast interpretation of thromboelastometry in non-cardiac surgery: reliability in patients with hypo-, normo-, and hypercoagulability.

  2013cited by this paper
• Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): A randomised, placebo-controlled trial

  2012cited by this paper
• Early platelet dysfunction: an unrecognized role in the acute coagulopathy of trauma.

  2012cited by this paper
• Fibrinogen levels during trauma hemorrhage, response to replacement therapy, and association with patient outcomes

  2012cited by this paper
• Early coagulopathy in trauma patients: an on-scene and hospital admission study.

  2012cited by this paper
• The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.

  2011cited by this paper
• A High Admission Syndecan-1 Level, A Marker of Endothelial Glycocalyx Degradation, Is Associated With Inflammation, Protein C Depletion, Fibrinolysis, and Increased Mortality in Trauma Patients

  2011cited by this paper
• Clotting factor deficiency in early trauma-associated coagulopathy.

  2011cited by this paper
• Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.

  2011influential reference
• The effect of FFP:RBC ratio on morbidity and mortality in trauma patients based on transfusion prediction score

  2011cited by this paper
• protocolProtocol for a randomised controlled trial investigating the effectiveness of an online e-health application compared to attention placebo or sertraline in the treatment of generalised anxiety disorder

  2010cited by this paper
• Gerinnungsmanagement bei traumatisch bedingter Massivblutung – Empfehlungen der Arbeitsgruppe für perioperative Gerinnung der ÖGARI

  2010cited by this paper
• Recovery of fibrinogen after administration of fibrinogen concentrate to patients with severe bleeding after cardiopulmonary bypass surgery

  2010cited by this paper
• Damage control resuscitation in combination with damage control laparotomy: a survival advantage.

  2010cited by this paper
• Management of bleeding following major trauma: an updated European guideline

  2010cited by this paper
• The role of rotation thromboelastometry in early prediction of massive transfusion.

  2010cited by this paper
• Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM®)-guided administration of fibrinogen concentrate and prothrombin complex concentrate

  2010cited by this paper
• Primary Fibrinolysis Is Integral in the Pathogenesis of the Acute Coagulopathy of Trauma

  2010cited by this paper
• Pathophysiology and Treatment of Coagulopathy in Massive Hemorrhage and Hemodilution

  2010cited by this paper
• Results of the CONTROL trial: efficacy and safety of recombinant activated Factor VII in the management of refractory traumatic hemorrhage.

  2010cited by this paper
• Coagulopathy by hypothermia and acidosis: mechanisms of thrombin generation and fibrinogen availability.

  2009cited by this paper
• Hyperfibrinolysis after major trauma: differential diagnosis of lysis patterns and prognostic value of thrombelastometry.

  2009influential reference
• Point-of-care versus central laboratory coagulation testing during haemorrhagic surgery

  2009cited by this paper
• Time for changing coagulation management in trauma-related massive bleeding

  2009cited by this paper
• Transfusion in trauma: why and how should we change our current practice?

  2009cited by this paper
• Massive transfusion protocols: the role of aggressive resuscitation versus product ratio in mortality reduction.

  2009cited by this paper
• Fresh frozen plasma is independently associated with a higher risk of multiple organ failure and acute respiratory distress syndrome.

  2009cited by this paper
• The relationship of blood product ratio to mortality: survival benefit or survival bias?

  2009cited by this paper
• Coagulation Monitoring: Current Techniques and Clinical Use of Viscoelastic Point-of-Care Coagulation Devices

  2008cited by this paper
• Prothrombin complex concentrate (Beriplex® P/N) for emergency anticoagulation reversal: a prospective multinational clinical trial

  2008cited by this paper
• Acute coagulopathy of trauma: hypoperfusion induces systemic anticoagulation and hyperfibrinolysis.

  2008cited by this paper
• Red blood cell to plasma ratios transfused during massive transfusion are associated with mortality in severe multiply injury: a retrospective analysis from the Trauma Registry of the Deutsche Gesellschaft für Unfallchirurgie

  2008cited by this paper
• The coagulopathy of trauma: a review of mechanisms.

  2008cited by this paper
• Postinjury life threatening coagulopathy: is 1:1 fresh frozen plasma:packed red blood cells the answer?

  2008cited by this paper
• Management of coagulopathy in the patients with multiple injuries: results from an international survey of clinical practice.

  2008influential reference
• Evaluation of rotation thrombelastography for the diagnosis of hyperfibrinolysis in trauma patients.

  2008cited by this paper
• Shedding of the Endothelial Glycocalyx in Patients Undergoing Major Vascular Surgery With Global and Regional Ischemia

  2007cited by this paper
• Acute Traumatic Coagulopathy: Initiated by Hypoperfusion: Modulated Through the Protein C Pathway?

  2007cited by this paper
• Prevention and treatment of major blood loss.

  2007cited by this paper
• Fresh-frozen plasma and platelet transfusions are associated with development of acute lung injury in critically ill medical patients.

  2007cited by this paper
• Fresh frozen plasma should be given earlier to patients requiring massive transfusion.

  2007cited by this paper
• European Journal of Trauma and Emergency Surgery

  2007cited by this paper
• The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital.

  2007cited by this paper
• The resuscitative fluid you choose may potentiate bleeding.

  2006cited by this paper
• Effect of fresh‐frozen plasma transfusion on prothrombin time and bleeding in patients with mild coagulation abnormalities

  2006cited by this paper
• The endothelial glycocalyx: a potential barrier between health and vascular disease

  2005cited by this paper
• Effect of fibrinogen on reversal of dilutional coagulopathy: a porcine model.

  2005cited by this paper
• Molecular mechanisms of fibrinolysis

  2005cited by this paper
• Are we giving enough coagulation factors during major trauma resuscitation?

  2005cited by this paper
• Fresh frozen plasma transfusion in critically ill medical patients with coagulopathy*

  2005cited by this paper
• Regulation of Weibel-Palade body exocytosis.

  2005cited by this paper
• Recombinant factor VIIa as adjunctive therapy for bleeding control in severely injured trauma patients: two parallel randomized, placebo-controlled, double-blind clinical trials.

  2005influential reference
• FIFTH EDITION

  2004cited by this paper
• A systematic evaluation of the effect of temperature on coagulation enzyme activity and platelet function.

  2004cited by this paper
• Thrombelastography. Present and future perspectives in clinical practice.

  2003cited by this paper
• The effect of temperature and pH on the activity of factor VIIa: implications for the efficacy of high-dose factor VIIa in hypothermic and acidotic patients.

  2003cited by this paper
• Effect of in vitro hemodilution with hydroxyethyl starch and dextran on the activity of plasma clotting factors

  2003cited by this paper
• A cell-based model of coagulation and the role of factor VIIa.

  2003cited by this paper
• Treating coagulopathy in trauma patients.

  2003cited by this paper
• In vivo effect of haemodilution with saline on coagulation.

  2002cited by this paper
• Does prehospital fluid administration impact core body temperature and coagulation functions in combat casualties?

  2002cited by this paper
• The Effect of the Combined Administration of Colloids and Lactated Ringer’s Solution on the Coagulation System: An In Vitro Study Using Thrombelastograph® Coagulation Analysis (ROTEG®)

  2002cited by this paper
• Effects on coagulation of intravenous crystalloid or colloid in patients undergoing peripheral vascular surgery.

  2002cited by this paper
• Is the normalisation of blood pressure in bleeding trauma patients harmful?

  2001cited by this paper
• The global burden of injuries.

  2000cited by this paper
• Trauma triad of death. Emergency!

  2000cited by this paper
• Thromboelastography-guided transfusion algorithm reduces transfusions in complex cardiac surgery.

  1999cited by this paper
• Thrombelastogram reveals hypercoagulability after administration of gelatin solution.

  1999cited by this paper
• An international view of hydroxyethyl starches

  1999cited by this paper
• Marked temperature dependence of the platelet calcium signal induced by human von Willebrand factor.

  1999cited by this paper
• Crystalloids vs. colloids in fluid resuscitation: a systematic review.

  1999cited by this paper
• Fluid resuscitation with colloid or crystalloid solutions in critically ill patients: a systematic review of randomised trials

  1998cited by this paper
• Reduced quality of clot formation with gelatin-based plasma substitutes.

  1998cited by this paper
• Mortality by cause for eight regions of the world: Global Burden of Disease Study

  1997cited by this paper
• Hematocrit as a predictor of significant injury after penetrating trauma.

  1997cited by this paper
• Is hypothermia in the victim of major trauma protective or harmful? A randomized, prospective study.

  1997cited by this paper
• Haemodilution induces a hypercoagulable state.

  1996cited by this paper
• Large-Dose Administration of 6% Hydroxyethyl Starch 200/0.5 for Total Hip Arthroplasty: Plasma Homeostasis, Hemostasis, and Renal Function Compared to Use of 5% Human Albumin

  1996cited by this paper
• The Thromboelastograph and the Thromboelastograph Technique

  1995cited by this paper
• Fibrinolytic activity during orthotopic liver transplantation with and without aprotinin.

  1994cited by this paper
• Epidemiology of trauma deaths: a reassessment.

  1993cited by this paper

• Early coagulation changes as predictors of adverse outcomes in patients with severe burn and inhalation injuries.

  2025cites this paper
• All-in-One: A Multifunctional Composite Biomimetic Cryogel for Coagulation Disorder Hemostasis and Infected Diabetic Wound Healing

  2025cites this paper
• Integrated single-cell multiomics reveals novel immune candidate markers for post-traumatic coagulopathy

  2023cites this paper
• Does Antithrombotic Therapy Affect Outcomes in Major Trauma Patients? A Retrospective Cohort Study from a Tertiary Trauma Centre

  2022cites this paper
• Personalized modulation of coagulation factors using a thrombin dynamics model to treat trauma-induced coagulopathy

  2021cites this paper
• A new trauma frontier: Exploratory pilot study of platelet transcriptomics in trauma patients

  2021cites this paper
• A Review of Neutrophil Extracellular Traps (NETs) in Disease: Potential Anti-NETs Therapeutics

  2020cites this paper
• Coagulation Management

  2020cites this paper
• Higher coagulation activity in hip fracture patients: A case‐control study using rotational thromboelastometry

  2020cites this paper