Tumor and Stem Cell Biology Cancer Research BRD 7 , a Subunit of SWI / SNF Complexes , Binds Directly to BRCA 1 and Regulates BRCA 1-Dependent Transcription

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Not labeled

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• The SWI/SNF complex and cancer

  2009cited by this paper
• BRD7, a Novel PBAF-specific SWI/SNF Subunit, Is Required for Target Gene Activation and Repression in Embryonic Stem Cells*

  2008cited by this paper
• BAF60a Interacts with p53 to Recruit the SWI/SNF Complex*

  2008cited by this paper
• BRD7 suppresses the growth of Nasopharyngeal Carcinoma cells (HNE1) through negatively regulating β-catenin and ERK pathways

  2007cited by this paper
• Solution structure of BRD7 bromodomain and its interaction with acetylated peptides from histone H3 and H4.

  2007cited by this paper
• The transcriptional regulation role of BRD7 by binding to acetylated histone through bromodomain

  2006cited by this paper
• The role of BRCA1 in transcriptional regulation and cell cycle control

  2006influential reference
• The 2,5 oligoadenylate synthetase/RNaseL pathway is a novel effector of BRCA1- and interferon-γ-mediated apoptosis

  2005cited by this paper
• BRCA1 and c-Myc associate to transcriptionally repress psoriasin, a DNA damage-inducible gene.

  2005cited by this paper
• BAF57 Governs Androgen Receptor Action and Androgen-Dependent Proliferation through SWI/SNF

  2005cited by this paper
• PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon-responsive genes.

  2005cited by this paper
• Composition and functional specificity of SWI2/SNF2 class chromatin remodeling complexes.

  2005cited by this paper
• BRCA1 and BRCA2: 1994 and beyond

  2004cited by this paper
• BRD7, a novel bromodomain gene, inhibits G1–S progression by transcriptionally regulating some important molecules involved in ras/MEK/ERK and Rb/E2F pathways

  2004cited by this paper
• Targeting of SWI/SNF chromatin remodelling complexes to estrogen‐responsive genes

  2002cited by this paper
• BRCA1 induces DNA damage recognition factors and enhances nucleotide excision repair

  2002cited by this paper
• BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer.

  2000influential reference
• Molecular characterization of Celtix‐1, a bromodomain protein interacting with the transcription factor interferon regulatory factor 2

  2000cited by this paper
• Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.

  1999cited by this paper

• Dependence on MUC1-C in Progression of Neuroendocrine Prostate Cancer

  2023cites this paper
• Actionability classification of variants of unknown significance correlates with functional effect

  2023cites this paper
• In Silico Identification of a BRCA1:miR-29:DNMT3 Axis Involved in the Control of Hormone Receptors in BRCA1-Associated Breast Cancers

  2023cites this paper
• Granular cell tumors of the urethra.

  2023cites this paper
• Epigenetic modulation by targeting bromodomain containing protein 9 (BRD9): Its therapeutic potential and selective inhibition.

  2023cites this paper
• Identification of the most common BRCA alterations through analysis of germline mutation databases: Is droplet digital PCR an additional strategy for the assessment of such alterations in breast and ovarian cancer families?

  2022cites this paper
• Upregulation of BRD7 protects podocytes against high glucose-induced apoptosis by enhancing Nrf2 in a GSK-3β-dependent manner.

  2022cites this paper
• BRD7 Stabilizes P53 via Dephosphorylation of MDM2 to Inhibit Tumor Growth in Breast Cancer Harboring Wild-type P53

  2022cites this paper
• Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers

  2022cites this paper
• LncRNA LENGA acts as a tumor suppressor in gastric cancer through BRD7/TP53 signaling

  2022cites this paper
• BRD7 Promotes Cell Proliferation and Tumor Growth Through Stabilization of c-Myc in Colorectal Cancer

  2021cites this paper
• MUC1-C activates the PBAF chromatin remodeling complex in integrating redox balance with progression of human prostate cancer stem cells

  2021cites this paper
• Functional Roles of Bromodomain Proteins in Cancer

  2021cites this paper
• BRD7 inhibits tumor progression by positively regulating the p53 pathway in hepatocellular carcinoma

  2021cites this paper
• Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target

  2021cites this paper
• The Role of ARID1A in Tumors: Tumor Initiation or Tumor Suppression?

  2021cites this paper
• The fellowship of the RING: BRCA1, its partner BARD1 and their liaison in DNA repair and cancer.

  2021cites this paper
• OCT1 Is a Poor Prognostic Factor for Breast Cancer Patients and Promotes Cell Proliferation via Inducing NCAPH

  2021cites this paper
• The regulatory subunits of PI3K, p85α and p85β, differentially affect BRD7-mediated regulation of insulin signaling

  2021cites this paper
• Targeting BRD9 for Cancer Treatment: A New Strategy

  2020cites this paper
• OTT_A_286867 13191..13200

  2020cites this paper
• BRD7-Mediated miR-3148 Inhibits Progression of Cervical Cancer by Targeting Wnt3a/β-Catenin Pathway

  2020cites this paper
• Expression and subcellular localization of the bromodomain-containing protein 7 is a prognostic biomarker in breast cancer

  2020cites this paper
• BRD7 suppresses invasion and metastasis in breast cancer by negatively regulating YB1-induced epithelial-mesenchymal transition

  2020cites this paper
• Histone Modifying Enzymes and Chromatin Modifiers in Glioma Pathobiology and Therapy Responses.

  2020cites this paper
• The antitumorigenic roles of BRCA1–BARD1 in DNA repair and replication

  2020cites this paper
• Emerging Roles of BRD7 in Pathophysiology

  2020influential citation
• ATM‐Dependent Recruitment of BRD7 is required for Transcriptional Repression and DNA Repair at DNA Breaks Flanking Transcriptional Active Regions

  2020cites this paper
• BRD7 deficiency leads to the development of obesity and hyperglycemia

  2019cites this paper
• Orthogonal Proteomic Platforms and Their Implications for the Stable Classification of High-Grade Serous Ovarian Cancer Subtypes

  2019cites this paper
• The BRCA1 c.4096+3A>G Variant Displays Classical Characteristics of Pathogenic BRCA1 Mutations in Hereditary Breast and Ovarian Cancers, But Still Allows Homozygous Viability

  2019cites this paper
• RNA–DNA hybrids and the convergence with DNA repair

  2019cites this paper
• BRD9 binds cell type-specific chromatin regions regulating leukemic cell survival via STAT5 inhibition

  2019cites this paper
• BRCA1-associated R-loop affects transcription and differentiation in breast luminal epithelial cells

  2019cites this paper
• BRD7 expression and c-Myc activation forms a double-negative feedback loop that controls the cell proliferation and tumor growth of nasopharyngeal carcinoma by targeting oncogenic miR-141

  2018cites this paper
• Biological function and histone recognition of family IV bromodomain‐containing proteins

  2018cites this paper
• Genomic Network-Based Analysis Reveals Pancreatic Adenocarcinoma Up-Regulating Factor-Related Prognostic Markers in Cervical Carcinoma

  2018cites this paper
• Bromodomain-containing protein 7 sensitizes breast cancer cells to paclitaxel by activating Bcl2-antagonist/killer protein

  2018cites this paper
• BARD1 is necessary for ubiquitylation of nucleosomal histone H2A and for transcriptional regulation of estrogen metabolism genes

  2018cites this paper
• Chapter 7 The BRCA 1 and BRCA 2 Breast and Ovarian Cancer Susceptibility Genes — Implications for DNA Damage Response , DNA Repair and Cancer Therapy

  2018cites this paper
• BRCA1 mutation spectrum, functions, and therapeutic strategies: The story so far.

  2018cites this paper
• Detection and evaluation of estrogen DNA‐adducts and their carcinogenic effects in cultured human cells using biotinylated estradiol

  2017cites this paper
• A genomic screen for angiosuppressor genes in the tumor endothelium identifies a multifaceted angiostatic role for bromodomain containing 7 (BRD7)

  2017influential citation
• LDB2 inhibits proliferation and migration in liver cancer cells by abrogating HEY1 expression

  2017cites this paper
• The BRCA 1 and BRCA 2 Breast and Ovarian Cancer Susceptibility Genes — Implications for DNA Damage Response , DNA Repair and Cancer Therapy

  2017cites this paper
• Breast cancer predisposition gene brca1, pathogenic c61g mutation in mice: synthetic viability in DNA repair and tumour development

  2016cites this paper
• Histone Modifications and Cancer.

  2016cites this paper
• The Oct1 transcription factor and epithelial malignancies: Old protein learns new tricks.

  2016cites this paper
• Bromodomain-containing protein 7 (BRD7) as a potential tumor suppressor in hepatocellular carcinoma

  2016cites this paper
• Tumor Suppressor Bromodomain-containing Protein 7 Cooperates with Smads to Promote Transforming Growth Factor-β Responses

  2016cites this paper
• Bromodomain inhibitors and cancer therapy: From structures to applications

  2016cites this paper
• Disrupting Acetyl-Lysine Recognition: Progress in the Development of Bromodomain Inhibitors.

  2016cites this paper
• BRD7: a novel tumor suppressor gene in different cancers.

  2016influential citation
• NMR Fragment Screening Hit Induces Plasticity of BRD7/9 Bromodomains

  2016cites this paper
• The level of the Phf10 protein, a PBAF chromatin-remodeling complex subunit, correlates with the Mts1/S100A4 expression in human cancer cell lines

  2016cites this paper
• Acetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and Cancer

  2016cites this paper
• miR-141 is involved in BRD7-mediated cell proliferation and tumor formation through suppression of the PTEN/AKT pathway in nasopharyngeal carcinoma

  2016cites this paper
• Whole-genome sequencing of a malignant granular cell tumor with metabolic response to pazopanib

  2015influential citation
• LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor†

  2015cites this paper
• BRCA1, a ‘complex’ protein involved in the maintenance of genomic stability

  2015cites this paper
• PBRM1: A Critical Subunit of the SWI/SNF Chromatin Remodeling Complex

  2015cites this paper
• Design and synthesis of potent and selective inhibitors of BRD7 and BRD9 bromodomains

  2015cites this paper
• Up-Regulation of MiR-300 Promotes Proliferation and Invasion of Osteosarcoma by Targeting BRD7

  2015cites this paper
• MicroRNA‐410 promotes cell proliferation by targeting BRD7 in non‐small cell lung cancer

  2015cites this paper
• BRCA1 functions as a novel transcriptional cofactor in HIV-1 infection

  2015cites this paper
• Transcriptional regulation prediction of antiestrogen resistance in breast cancer based on RNA polymerase II binding data

  2014cites this paper
• BRD7, a tumor suppressor, interacts with p85α and regulates PI3K activity.

  2014cites this paper
• Preparation of polyclonal antibody highly specific for mouse BRD7 protein and its application.

  2014cites this paper
• Chromatin remodeler mutations in human cancers: epigenetic implications.

  2014cites this paper
• DEVELOPMENT OF A FUNCTIONAL ASSAY FOR DETERMINATION OF BRCA1 CARRIER STATUS

  2014cites this paper
• NF-k B is a critical mediator of BRCA 1-induced chemoresistance

  2013cites this paper
• The regulation of p53 transcriptional activity by hnRNPUL-1 and the DNA damage response induced by a novel chemotherapeutic agent, ALX

  2013cites this paper
• Chromatin organisation in breast cancer

  2013cites this paper
• Prognostic relevance of BRD7 expression in colorectal carcinoma

  2013cites this paper
• A whole‐genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor‐negative and ‐positive breast cancers

  2012cites this paper
• THE NRF-1/GABP/BRCA1 Transcriptional Network in Mammary Epithelial Differentiation

  2012influential citation
• Identifying novel components of human tumour suppressor networks

  2012cites this paper
• Mutation Analysis of BRCA1, BRCA2, PALB2 and BRD7 in a Hospital-Based Series of German Patients with Triple-Negative Breast Cancer

  2012cites this paper
• Frequent low expression of chromatin remodeling gene ARID1A in breast cancer and its clinical significance.

  2012cites this paper
• The RSC and INO80 chromatin-remodeling complexes in DNA double-strand break repair.

  2012cites this paper
• No evidence for breast cancer susceptibility associated with variants of BRD7, a component of p53 and BRCA1 pathways

  2012cites this paper
• Investigating the role of 53BP1 in regulating gene transcription.

  2011cites this paper
• Roles of SWI/SNF Complex Genes in Breast Cancer

  2011cites this paper
• Profiling of the BRCA1 transcriptome through microarray and ChIP-chip analysis

  2011cites this paper
• Gene regulation and tumor suppression by the bromodomain-containing protein BRD7

  2010cites this paper