A genetic linkage map of the canine genome has been developed by typing 150 microsatellite markers using 17 three-generation pedigrees, composed of 163 F2 individuals. One hundred and thirty-nine markers were linked to at least one other marker with a lod score > or = 3.0, identifying 30 linkage groups. The largest chromosome had 9 markers spanning 106.1 cM. The average distance between markers was 14.03 cM, and the map covers an estimated 2073 cM. Eleven markers were informative on the mapping panel, but were unlinked to any other marker. These likely represent single markers located on small, distinct canine chromosomes. This map will be the initial resource for mapping canine traits of interest and serve as a foundation for development of a comprehensive canine genetic map.
A linkage map of the canine genome.
C. Mellersh,A. Langston,G. Acland,M. Fleming,K. Ray,N. Wiegand,Leigh V. Francisco,M. Gibbs,G. Aguirre,E. Ostrander
Published 1997 in Genomics
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- Publication year
1997
- Venue
Genomics
- Publication date
1997-12-15
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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