Proteinases of the mammary gland: developmental regulation in vivo and vectorial secretion in culture.

No abstract is available for this paper.

• Publication year

  1991

• Venue

  Development

• Publication date

  1991-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 1794314PMCID PMC2975574
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Coordinated expression of extracellular matrix-degrading proteinases and their inhibitors regulates mammary epithelial function during involution

  1992cited by this paper
• Metalloproteinases and their inhibitors in matrix remodeling.

  1990cited by this paper
• Expression of extracellular matrix components is regulated by substratum

  1990cited by this paper
• Expression of extracellular matrix-degrading metalloproteinases and metalloproteinase inhibitors is developmentally regulated during endoderm differentiation of embryonal carcinoma cells.

  1990cited by this paper
• Designer microenvironments for the analysis of cell and tissue function.

  1990cited by this paper
• Proteinases and extracellular matrix remodeling.

  1989cited by this paper
• A novel regulatory mechanism for whey acidic protein gene expression.

  1989cited by this paper
• Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane.

  1989cited by this paper
• Genes for extracellular-matrix-degrading metalloproteinases and their inhibitor, TIMP, are expressed during early mammalian development.

  1989cited by this paper
• The activation of human type IV collagenase proenzyme. Sequence identification of the major conversion product following organomercurial activation.

  1989cited by this paper
• Mammary gland function during involution.

  1989cited by this paper
• Cellular interactions determining the production of collagenase by a rat mammary carcinoma cell line

  1989cited by this paper
• Proteinases and extracellular remodeling

  1989cited by this paper
• Growth factors in mammary gland function.

  1989cited by this paper
• Ras oncogene mediated induction of a 92 kDa metalloproteinase; strong correlation with the malignant phenotype.

  1988cited by this paper
• Effects of inhibitors of plasminogen activator, serine proteinases, and collagenase IV on the invasion of basement membranes by metastatic cells.

  1988cited by this paper
• H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.

  1988cited by this paper
• The role of interstitial collagens in cleft formation of mouse embryonic submandibular gland during initial branching.

  1988cited by this paper
• Degradation of glomerular basement membrane by purified mammalian metalloproteinases.

  1988cited by this paper
• Collagenase expression and endogenous activation in rabbit synovial fibroblasts stimulated by the calcium ionophore A23187.

  1988cited by this paper
• Plasminogen activator dependent pathways in the dissemination of human tumor cells in the chick embryo.

  1988cited by this paper
• Autocrine regulation of casein turnover in goat mammary explants.

  1988cited by this paper
• Development of the Human Mammary Gland

  1987cited by this paper
• Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells.

  1987cited by this paper
• The Influence of Extracellular Matrix on Gene Expression: Is Structure the Message?

  1987cited by this paper
• The activation of human skin fibroblast procollagenase. Sequence identification of the major conversion products.

  1987cited by this paper
• Regulation of rat mammary gene expression by extracellular matrix components.

  1987cited by this paper
• Milk protein expression and ductal morphogenesis in the mammary gland in vitro: hormone-dependent and -independent phases of adipocyte-mammary epithelial cell interaction.

  1987cited by this paper
• Basement membrane complexes with biological activity.

  1986cited by this paper
• Reorganization of polymerized actin: a possible trigger for induction of procollagenase in fibroblasts cultured in and on collagen gels

  1986cited by this paper
• Degradation of newly-synthesised casein in mammary explants from pregnant and lactating goats.

  1986cited by this paper
• Comparison of human stromelysin and collagenase by cloning and sequence analysis.

  1986cited by this paper
• Cathepsin B: association with plasma membrane in metastatic tumors.

  1986cited by this paper
• Secretion of metalloproteinases by stimulated capillary endothelial cells. II. Expression of collagenase and stromelysin activities is regulated by endogenous inhibitors.

  1986cited by this paper
• Tumor invasion and metastases--role of the extracellular matrix: Rhoads Memorial Award lecture.

  1986cited by this paper
• Secretion of metalloproteinases by stimulated capillary endothelial cells. I. Production of procollagenase and prostromelysin exceeds expression of proteolytic activity.

  1986cited by this paper
• Stromelysin, a connective tissue-degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. Biosynthesis, isolation, characterization, and substrates.

  1985cited by this paper
• Interaction of mouse mammary epithelial cells with collagen substrata: regulation of casein gene expression and secretion.

  1985cited by this paper
• Biochemistry and physiological function of human milk proteins.

  1985cited by this paper
• Localization of collagenase in the growth plate of rachitic rats.

  1985cited by this paper
• Modulation of secreted proteins of mouse mammary epithelial cells by the collagenous substrata

  1984cited by this paper
• Development of the mammary gland.

  1982cited by this paper
• Purification of rabbit bone inhibitor of collagenase.

  1981cited by this paper
• Effects of inhibition of basement membrane collagen deposition on rat mammary gland development.

  1980cited by this paper
• Mammary plasminogen activator: correlation with involution, hormonal modulation and comparison between normal and neoplastic tissue.

  1979cited by this paper
• Direct fluorescent assay of urokinase and plasminogen activators of normal and malignant cells: kinetics and inhibitor profiles.

  1978cited by this paper
• CHAPTER FOUR – Involution of the Mammary Gland

  1978cited by this paper
• Maintenance and induction of morphological differentiation in dissociated mammary epithelium on floating collagen membranes

  1977cited by this paper
• Removal of basement membrane in the involuting breast.

  1976cited by this paper
• Ovarian plasminogen activator: relationship to ovulation and hormonal regulation.

  1975cited by this paper
• [The mammary gland].

  1966cited by this paper
• Growth of Mouse Mammary Glands in vivo after Monolayer Culture

  1965cited by this paper
• THE CHICK EMBRYO

  1965cited by this paper
• Development of the Mammary Gland*

  1882cited by this paper

• Investigating the interplay between the mir-183/182/96 cluster and the adherens junction pathway in early-stage breast cancer

  2024cites this paper
• Endotoxin Triggers Tumor Initiation Events in Nontumorigenic Breast Epithelial Cells and Enhances Invasion-Related Phenotype in Pretumorigenic and Tumorigenic Breast Epithelial Cells

  2021cites this paper
• Stem Cells and Cellular Origins of Mammary Gland: Updates in Rationale, Controversies, and Cancer Relevance

  2019cites this paper
• Normal mammary gland development after MMTV-Cre mediated conditional PAK4 gene depletion

  2019cites this paper
• Role of the Microenvironment in Regulating Normal and Cancer Stem Cell Activity: Implications for Breast Cancer Progression and Therapy Response

  2019cites this paper
• Maintenance Of Mammary Epithelial Phenotype By Transcription Factor Runx1 Through Mitotic Gene Bookmarking

  2019cites this paper
• AWARD NUMBER: W81XWH-17-1-0470 TITLE: Targeted Lung-Derived Proteins as a Therapeutic Strategy Against Breast Cancer Metastasis

  2019cites this paper
• The cJUN NH2-terminal kinase (JNK) pathway contributes to mouse mammary gland remodeling during involution

  2018cites this paper
• A Selective Extracellular Matrix Proteomics Approach Identifies Fibronectin Proteolysis by A Disintegrin-like and Metalloprotease Domain with Thrombospondin Type 1 Motifs (ADAMTS16) and Its Impact on Spheroid Morphogenesis *

  2018cites this paper
• A selective extracellular matrix proteomics approach identifies fibronectin proteolysis by ADAMTS16 and its impact on spheroid morphogenesis

  2018cites this paper
• The cJUN NH2-terminal kinase pathway in mammary gland biology and carcinogenesis

  2018cites this paper
• The Chemical Composition of Achillea wilhelmsii C. Koch and Its Desirable Effects on Hyperglycemia, Inflammatory Mediators and Hypercholesterolemia as Risk Factors for Cardiometabolic Disease

  2016cites this paper
• Reversible Aptamer-Au Plasmon Rulers for Secreted Single Molecules.

  2015cites this paper
• Characterization of the Stromal and Epithelial Pathways in the Mammary Gland causing Susceptibility to Cancer

  2015cites this paper
• Characterization and Comparative Analysis of the Milk Transcriptome in Two Dairy Sheep Breeds using RNA Sequencing

  2015cites this paper
• Mammary gland development: cell fate specification, stem cells and the microenvironment

  2015cites this paper
• From Microenvironment to Nanoenvironment: Ultrastructure and Function of Extracellular Matrix

  2014cites this paper
• Pharmacological and Molecular Effects of Platinum(II) Complexes Involving 7-Azaindole Derivatives

  2014cites this paper
• during the menstrual cycle

  2014cites this paper
• Prenylated Flavonoids from Morus alba L. Cause Inhibition of G1/S Transition in THP-1 Human Leukemia Cells and Prevent the Lipopolysaccharide-Induced Inflammatory Response

  2013cites this paper
• The involvement of MMP-2 and MMP-9 in heart exercise-related angiogenesis

  2013cites this paper
• The hemopexin domain of MMP 3 is responsible for mammary epithelial invasion and morphogenesis through extracellular interaction with HSP 90 b

  2013cites this paper
• Microenvironmental regulation of epithelial-mesenchymal transition

  2013cites this paper
• Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1

  2013cites this paper
• The hemopexin domain of MMP3 is responsible for mammary epithelial invasion and morphogenesis through extracellular interaction with HSP90β.

  2013cites this paper
• Microenvironmental regulators of mammary gland architecture: the role of matrix metalloproteinase 3 in epithelial invasion and branching morphogenesis

  2013cites this paper
• Three-dimensional cultures of mouse mammary epithelial cells.

  2013cites this paper
• Elevated CSF1 serum concentration predicts poor overall survival in women with early breast cancer.

  2013cites this paper
• Effect of 2-Chloro-Substitution of Adenine Moiety in Mixed-Ligand Gold(I) Triphenylphosphine Complexes on Anti-Inflammatory Activity: The Discrepancy between the In Vivo and In Vitro Models

  2013cites this paper
• Dedifferentiation-specific expression of MMP-9 and the effects of RA on its expression during salamander limb regeneration

  2013cites this paper
• Matrix compliance regulates Rac1b localization, NADPH oxidase assembly, and epithelial–mesenchymal transition

  2012cites this paper
• Intercellular Signalling in the Mammary Gland

  2012cites this paper
• AT1 receptor blockade delays postlactational mammary gland involution: a novel role for the renin angiotensin system

  2012cites this paper
• Mammary gland reprogramming: metalloproteinases couple form with function.

  2011cites this paper
• Investigating maspin in breast cancer progression using mouse models.

  2011cites this paper
• The metastasis-promoting protein S100A4 regulates mammary branching morphogenesis.

  2011cites this paper
• Role of MMPs in metastatic dissemination: implications for therapeutic advances.

  2011cites this paper
• Emulsion Templated Porous Scaffolds for Bone Tissue Engineering

  2010cites this paper
• Stromelysin-1 (MMP-3) is a target and a regulator of Wnt1-induced epithelial-mesenchymal transition (EMT)

  2010cites this paper
• Design of three-dimensional biomimetic scaffolds.

  2010cites this paper
• Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways.

  2010influential citation
• Breast cancer by proxy: can the microenvironment be both the cause and consequence?

  2009cites this paper
• Estrogen and progesterone receptors have distinct roles in the establishment of the hyperplastic phenotype in PR-A transgenic mice

  2009cites this paper
• Macrophages in Breast Cancer: Do Involution Macrophages Account for the Poor Prognosis of Pregnancy-Associated Breast Cancer?

  2009cites this paper
• Tissue architecture and function: dynamic reciprocity via extra- and intra-cellular matrices

  2009cites this paper
• Lactoferrin at basal side of mouse mammary epithelium derives in part from stroma cells

  2009cites this paper
• Cholinoceptor modulation on nitric oxide regulates prostaglandin E(2) and metalloproteinase-3 production in experimentally induced inflammation of rat dental pulp.

  2009cites this paper
• Sustained activation of STAT5 is essential for chromatin remodeling and maintenance of mammary-specific function

  2009cites this paper
• Mammary Involution and Breast Cancer Risk: Transgenic Models and Clinical Studies

  2009cites this paper
• Role of manganese superoxide dismutase on growth and invasive properties of human estrogen-independent breast cancer cells

  2008cites this paper
• Top-Down Analysis of a Dynamic Environment: Extracellular Matrix Structure and Function

  2008cites this paper
• Secretion of Matrix Metalloproteinases and Their Inhibitors ( Tissue Inhibitor of Metalloproteinases ) by Human Prostate in Explant Cultures : Reduced Tissue Inhibitor of Metailoproteinase Secretion by Malignant Tissues 1

  2007cites this paper
• Architecture Is the Message: The role of extracellular matrix and 3-D structure in tissue-specific gene expression and breast cancer.

  2007cites this paper
• Microenvironment of the Involuting Mammary Gland Mediates Mammary Cancer Progression

  2007cites this paper
• Biologie de la lactation

  2007cites this paper
• Lack of plasminogen leads to milk stasis and premature mammary gland involution during lactation.

  2006cites this paper
• One of the duplicated matrix metalloproteinase‐9 genes is expressed in regressing tail during anuran metamorphosis

  2006cites this paper
• Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer.

  2006cites this paper
• Epidermal stem cells of the skin.

  2006cites this paper
• The multiple roles of Id-1 in cancer progression.

  2006cites this paper
• Pregnancy-associated breast cancer and metastasis

  2006cites this paper
• Control of basement membrane remodeling and epithelial branching morphogenesis in embryonic lung by Rho and cytoskeletal tension

  2005cites this paper
• Gene expression and differentiation

  2005cites this paper
• ECM degrading proteases and tissue remodelling in the mammary gland

  2005cites this paper
• Matrix degrading metalloproteinases

  2005cites this paper
• Expression of the stromelysin-3 gene in fibroblastic cells of invasive carcinomas of the breast and other human tissues: a review

  2005cites this paper
• Reduction of Human Metastatic Breast Cancer Cell Aggressiveness on Introduction of Either Form A or B of the Progesterone Receptor and Then Treatment with Progestins

  2004cites this paper
• Apoptosis regulation in the mammary gland

  2004cites this paper
• MMP‐2 plays an essential role in producing epithelial‐mesenchymal transformations in the avian embryo

  2004cites this paper
• Malignant Mammary Cells Acquire Independence from Extracellular Context for Regulation of Estrogen Receptor α

  2004cites this paper
• Growth hormone releasing hormone reverses endotoxin-induced localized inflammatory hyperalgesia without reducing the upregulated cytokines, nerve growth factor and gelatinase activity.

  2004cites this paper
• Relaxin modulates cardiac fibroblast proliferation, differentiation, and collagen production and reverses cardiac fibrosis in vivo.

  2004cites this paper
• The effect of endotoxin on functional parameters of mammary CID-9 cells.

  2004cites this paper
• Co‐stimulation of human breast cancer cells with transforming growth factor‐β and tenascin‐C enhances matrix metalloproteinase‐9 expression and cancer cell invasion

  2004cites this paper
• Prolactin and transforming growth factor-beta signaling exert opposing effects on mammary gland morphogenesis, involution, and the Akt-forkhead pathway.

  2004cites this paper
• The Role of CSF-1 in Normal Physiology of Mammary Gland and Breast Cancer: An Update

  2004cites this paper
• CAMBIOS FENOTÍPICOS DEL EPITELIO MAMARIO INDUCIDOS POR SU ENTORNO CELULAR

  2004cites this paper
• Regulation of mammary gland branching morphogenesis by the extracellular matrix and its remodeling enzymes

  2003cites this paper
• Tumor Necrosis Factor-α (TNF-α) Stimulates Chemotactic Response in Mouse Myogenic Cells

  2003cites this paper
• Immune Enhancement of Skin Carcinogenesis by CD4+ T Cells

  2003cites this paper
• Tenascin‐C upregulates matrix metalloproteinase‐9 in breast cancer cells: Direct and synergistic effects with transforming growth factor β1

  2003cites this paper
• Immune Enhancement of Skin Carcinogenesis by CD4 (cid:2) T Cells

  2003cites this paper
• Tumor necrosis factor-alpha (TNF-alpha) stimulates chemotactic response in mouse myogenic cells.

  2003cites this paper
• PII: 0022-202X(93)90497-6

  2003cites this paper
• Inducible dimerization of FGFR1

  2002influential citation
• Proteomic Dissection of Dome Formation in a Mammary Cell Line

  2002cites this paper
• 703 Inducible dimerization of FGFR1: development of a mouse model to analyze progressive transformation of the mammary

  2002cites this paper
• Extracellular matrix remodeling and metalloproteinase involvement during intestine regeneration in the sea cucumber Holothuria glaberrima.

  2002cites this paper
• Mammary gland involution is delayed by activated Akt in transgenic mice.

  2001cites this paper
• Proteomic dissection of dome formation in a mammary cell line: Role of tropomyosin-5b and maspin

  2001cites this paper
• The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cells.

  2001cites this paper
• A plasma kallikrein-dependent plasminogen cascade required for adipocyte differentiation

  2001cites this paper
• Functional role of matrix metalloproteinases (MMPs) in mammary epithelial cell development

  2001influential citation
• Matrix Metalloproteinases-2 and 9 Do Not Play a Role in the Growth of Preneoplastic Liver Lesions in F344 Rats

  2001cites this paper
• Partial purification and characterization of proteins with growth promoting activities from ovine mammary gland secretions.

  2001cites this paper
• Matrix metalloproteinase-2 is associated with tenascin-C in calcific aortic stenosis.

  2001cites this paper
• Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor

  2001cites this paper
• Accelerated apoptosis in the Timp-3-deficient mammary gland.

  2001cites this paper
• MMP-9 Supplied by Bone Marrow – Derived Cells Contributes to Skin Carcinogenesis

  2000cites this paper
• Matrix metalloproteinase-9 triggers the angiogenic switch during

  2000cites this paper