Letter: Rapid, sensitive microassay for platelet 5HT.

No abstract is available for this paper.

• Publication year

  1974

• Venue

  Thrombosis et diathesis haemorrhagica

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  PMID 4852909
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Conjoint native and orthophthaldialdehyde-condensate assays for the fluorimetric determination of 5-hydroxyindoles in brain

  2004cited by this paper
• Behaviour of endogenous and newly absorbed serotonin in the platelet release reaction.

  1973cited by this paper
• Optimum concentration of ortho-phthaldialdehyde for the fluorometric measurement of serotonin.

  1971cited by this paper
• Fluorometric detection of serotonin using o-phthaldialdehyde: An improvement

  1970cited by this paper
• Metabolism, subcellular transport and storage of 5-hydroxytryptamine in blood platelets.

  1968cited by this paper
• An improved method for the fluorimetric determination of 5-hydroxytryptamine in tissues.

  1967cited by this paper
• An easy method to determine the serotonin content of human platelets

  1962cited by this paper
• Fluorescence characteristics of 5-hydroxytryptamine (serotonin).

  1955cited by this paper

• Automation in Platelet Function Testing: Current Challenges and Future Directions

  2025cites this paper
• Platelet function abnormalities in acquired hemophilia A

  2025cites this paper
• A case of acquired transient bleeding diathesis associated with acquired platelet storage pool deficiency and defective thromboxane A2 production

  2024cites this paper
• Mepacrine Flow Cytometry Assay for the Diagnosis of Platelet δ-granule Defects: Literature Review on Methods—Towards a Shared Detailed Protocol

  2024cites this paper
• Serotonin secretion by blood platelets: accuracy of high-performance liquid chromatography-electrochemical technique compared with the isotopic test and use in a clinical laboratory

  2023cites this paper
• Evaluation of an automated platelet aggregation method for detection of congenital or acquired platelet function defects

  2023cites this paper
• Flow-chamber device (T-TAS) to diagnose patients suspected of platelet function defects

  2023cites this paper
• Impairment of platelet function in both mild and severe COVID‐19 patients

  2023cites this paper
• Expert opinion on the use of platelet secretion assay for the diagnosis of inherited platelet function disorders: Communication from the ISTH SSC Subcommittee on Platelet Physiology

  2022cites this paper
• Reduced platelet count, but no major platelet function abnormalities, are associated with loss-of-function ATP-binding cassette-1 gene mutations.

  2017cites this paper
• A review of platelet secretion assays for the diagnosis of inherited platelet secretion disorders

  2015cites this paper
• Bleeding on patients with autoimmune thrombocytopenic purpura and normal platelet count.

  2009cites this paper
• Platelet 5-hydroxytryptamine transport and storage in myeloproliferative disorders.

  2009cites this paper
• Which tests are most useful in distinguishing between reactive thrombocytosis and the thrombocytosis of myeloproliferative disease?

  2008cites this paper
• Platelets, arthus-type reactions and inflammatory mediators

  2005cites this paper
• Primary dysfunction in aggregation and secretion of SHRSP platelets: Not secondary to the circulation of “exhausted” platelets

  2004cites this paper
• Effects of a single oral dose of 3-cyano-imipramine on serotonin uptake and content of platelets in healthy volunteers

  2004cites this paper
• The effect of multiple rising doses of Ro 11-2465 (serotonin uptake inhibitor) on serotonin content of human platelets

  2004cites this paper
• Propranolol modifies platelet serotonergic mechanisms in rats.

  2002cites this paper
• Functional redundancy of Rab27 proteins and the pathogenesis of Griscelli syndrome.

  2002cites this paper
• Enhancement of human platelet activation by the combination of low concentrations of collagen and rabbit anticardiolipin antibodies

  2002cites this paper
• Determination of the cell lytic properties of amphiphilic inhibitors of the cytosolic phospholipase A2 against human platelets by measuring the liberation of serotonin with high-performance liquid chromatography and fluorescence detection.

  2002cites this paper
• Importance of Serotonergic Mechanisms in the Thrombotic Complications in Hemodialyzed Patients Treated with Erythropoietin

  2000cites this paper
• Evaluation of platelet function with the PFA-100 system in patients with congenital defects of platelet secretion.

  1999cites this paper
• Deficiency of (33P)2MeS-ADP Binding Sites on Platelets with Secretion Defect, Normal Granule Stores and Normal Thromboxane A2 Production

  1997cites this paper
• Human intraplatelet 5-hydroxytryptamine is correlated with mean platelet survival time.

  1996cites this paper
• Hemostatic Disorder of Uremia: The Platelet Defect, Main Determinant of the Prolonged Bleeding Time, Is Correlated with Indices of Activation of Coagulation and Fibrinolysis

  1996cites this paper
• Platelet aggregation and peripheral serotonergic system in kidney transplant recipients treated with cyclosporine.

  1996cites this paper
• Correlation between serotonin concentration and blood pressure in kidney transplant recipients treated with cyclosporine.

  1996cites this paper
• Conjugated Estrogens Shorten Bleeding Time in Uraemia: a Possible Role of Serotonin?

  1995cites this paper
• A study of platelet functions, some hemostatic and fibrinolytic parameters in relation to serotonin in hemodialyzed patients under erythropoietin therapy.

  1995cites this paper
• Decreased platelet counts and decreased platelet serotonin in poststreptococcal nephritis.

  1995cites this paper
• Aspirin inhibits collagen-induced platelet serotonin release, as measured by microbore high-performance liquid chromatography with electrochemical detection.

  1995cites this paper
• Magnolol inhibits collagen-induced platelet serotonin release.

  1995cites this paper
• Role of 5-hydroxytryptamine in platelet thrombus formation and mechanisms of inhibition of thrombus formation by 5-hydroxytryptamine2A antagonists in rabbits.

  1995cites this paper
• Accumulation of 5-Hydroxytryptamine by Aging Platelets: Studies in a Model of Suppressed Thrombopoiesis in Dogs

  1994cites this paper
• [The effect of tryptophan on the regulation of food intake in normal and overweight persons].

  1994cites this paper
• Serotonergic mechanisms are involved in the hemostatic action of erythropoietin in uremic patients

  1993cites this paper
• Detection of platelet-activating factor in plasma of patients with streptococcal nephritis.

  1993cites this paper
• Characterization of platelet hypofunctions in rats under SART stress (repeated cold stress).

  1993cites this paper
• Vitamin E did not prevent platelet activation, but prevented increase of lipid peroxides and renal dysfunction in DOCA-salt hypertensive rats.

  1993cites this paper
• [Effect of naftidrofuryl on viscoelasticity, thrombocyte aggregation and erythrocyte fluidity of blood].

  1992cites this paper
• Serotonin and hypertension in uraemia: a possible link?

  1992cites this paper
• DDAVP releases tPA in correlation with a fall in platelet serotonin in uraemic patients.

  1992cites this paper
• Whole blood serotonin levels in chronic renal failure.

  1992cites this paper
• Grey platelet syndrome: evidence for alpha-granule localization of the platelet plasminogen activator inhibitor-1 pool.

  1991cites this paper
• Platelet 5-Hydroxytryptamine Increases with Platelet Age in Dogs

  1991cites this paper
• Effects of protopine on blood platelet aggregation. III. Effect of protopine on the metabolic system of arachidonic acid in platelets.

  1991cites this paper
• [Interaction of CN-100, a novel non-steroidal anti-inflammatory drug, on biopolymers].

  1990cites this paper
• In Vitro Thromboxane Synthesis of Depleted Blood Platelets Following Renal Transplantation

  1990cites this paper
• [Thrombocyte function and thrombocyte-associated immunoglobulins in patients with systemic lupus erythematosus and chronic polyarthritis].

  1990cites this paper
• Purification and partial characterization of platelet-derived adherence-inhibiting factor in guinea pig.

  1989cites this paper
• Effect of heparin-PVA hydrogel on platelets in a chronic canine arterio-venous shunt.

  1989cites this paper
• Omega-3 fatty acid dietary supplementation in systemic lupus erythematosus.

  1989cites this paper
• Platelet function during long-term treatment with ketanserin of claudicating patients with peripheral atherosclerosis. A multi-center, double-blind, placebo-controlled trial. The PACK Trial Group.

  1989cites this paper
• Desmopressin Induces Decrease in Platelet Serotonin Content in Uremia

  1989cites this paper
• Platelet dysfunction in acute megakaryoblastic leukemia.

  1989cites this paper
• Early presence of activated ('exhausted') platelets in malignant tumors (breast adenocarcinoma and malignant melanoma).

  1989cites this paper
• Inhibitory effects of trimetazidine dihydrochloride on aggregation, serotonin release and malondialdehyde production in rabbit platelets.

  1988cites this paper
• Effects of nitroprusside and ketanserin upon pulmonary edema after acid injury.

  1988cites this paper
• Deficiency of intact thrombospondin and membrane glycoprotein Ia in platelets with defective collagen-induced aggregation and spontaneous loss of disorder.

  1988cites this paper
• Changes in both calcium pool size and morphology of human platelets incubated in various concentrations of calcium ion. Calcium-specific bleb formation on platelet-membrane surface.

  1988cites this paper
• Alteration of platelet serotonergic mechanisms and monoamine oxidase activity in premenstrual syndrome.

  1988cites this paper
• Intravascular platelet activation in the hemolytic uremic syndrome.

  1988cites this paper
• Intraplatelet serotonin in patients with diabetes mellitus and peripheral vascular disease

  1988cites this paper
• The effect of ethanol on some serotonergic mechanisms in rat blood platelets.

  1988cites this paper
• Studies on platelet function in patients with prostatic cancer. Preliminary report.

  1987cites this paper
• Vasoconstrictor expression of human platelet-vessel wall interactions: inhibition by the Ca2+ entry blocker flunarizine.

  1987cites this paper
• Verapamil inhibition of 5-hydroxytryptamine (5HT) uptake in rat platelets.

  1987cites this paper
• Localization of neutrophil adherence-inhibiting factor in guinea pig platelets.

  1987cites this paper
• Aspirin and risk of bleeding in patients with thrombocythemia.

  1987cites this paper
• Sequestration of serotonin in stored platelets

  1986cites this paper
• [Methods of studying platelet function. Biological markers of the activation of human platelets in vivo and in vitro].

  1986cites this paper
• Peri–operative management of carcinoid syndrome using ketanserin

  1986cites this paper
• Influence of ketanserin pretreatment on the haemodynamic responses to sternotomy

  1986cites this paper
• Effects of ketanserin, a selective 5-HT2 serotonergic antagonist, on the secondary recruitment of human plateletsin vitro

  1986cites this paper
• Comparative Study of Size, Total Protein, Fibrinogen and 5-HT Content of Human and Canine Platelet Density Subpopulations

  1986cites this paper
• Clinical pharmacology of tomoxetine, a potential antidepressant.

  1985cites this paper
• Inhibition of phospholipase A2 by tiaramide in rabbit platelets.

  1985cites this paper
• Platelet involvement in the nephritis of acute serum sickness in rabbits: protection by dipyridamole and FUT-175.

  1985cites this paper
• Platelet-mediated vascular permeability in the rat: a predominant role for 5-hydroxytryptamine.

  1985cites this paper
• The Appearance of “Exhausted” Platelets at the Time of Stroke in Stroke-Prone Spontaneously Hypertensive Rats

  1985cites this paper
• Inhibition of cold-induced vasoconstriction with ketanserin.

  1985cites this paper
• The appearance of exhausted platelets due to a duration of hypertension in stroke-prone spontaneously hypertensive rats.

  1985cites this paper
• Platelet-vessel wall interactions in hemostasis: Implication of 5-hydroxytryptamine

  1984cites this paper
• High Pressure Liquid Chromatography Microassay for Platelet Serotonin

  1984cites this paper
• The effects of platelet-derived contractile agents on human digital arteries.

  1984cites this paper
• Determinants of Cardiovascular Stability During Abdominal Aortic Aneurysmectomy (AAA)

  1984cites this paper
• Exhausted platelets in patients with malignant solid tumors without evidence of active consumption coagulopathy.

  1984cites this paper
• Increase in density and accumulation of serotonin by human aging platelets

  1984cites this paper
• Proton NMR studies of nucleotide and amine storage in the dense granules of pig platelets.

  1984cites this paper
• Myelofibrosis and megakaryoblastic transformation of chronic myelogenous leukemia associated with intrinsic platelet dysfunction: hematological, histological and ultrastructural findings.

  1984cites this paper
• 31P NMR studies of nucleotide storage in the dense granules of pig platelets.

  1984cites this paper
• Thrombin pretreatment of human platelets impairs thromboxane A2 synthesis from endogenous precursors in the presence of normal cyclooxygenase activity.

  1984cites this paper
• Thrombohaemorrhagic complications in 101 cases of myeloproliferative disorders: relationship to platelet number and function.

  1983cites this paper
• Impaired and exhausted platelets in modified generalized Shwartzman reaction: an analogue of hemolytic uremic syndrome associated with endotoxemia.

  1983cites this paper
• Ischemia of the limb stimulates thromboxane production and myocardial depression.

  1983cites this paper
• Platelet density analysis: a tool for the detection of acquired storage pool disease in man

  1983cites this paper
• Serotonin content of platelets in inflammatory rheumatic diseases. Correlation with clinical activity.

  1983cites this paper
• Experimental diabetes and platelet aggregation in the rat.

  1983cites this paper