Neurobehavioral abnormalities in first-degree relatives of individuals with autism.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Archives of General Psychiatry

• Publication date

  2010-08-01

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1001/archgenpsychiatry.2010.87PMID 20679591PMCID PMC3145411
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Sensorimotor transformation deficits for smooth pursuit in first-episode affective psychoses and schizophrenia.

  2010cited by this paper
• Cortical Serotonin Type-2 Receptor Density in Parents of Children with Autism Spectrum Disorders

  2009cited by this paper
• Effects of Risperidone on Procedural Learning in Antipsychotic-Naive First-Episode Schizophrenia

  2009cited by this paper
• Functional Magnetic Resonance Imaging Activations of Cortical Eye Fields during Saccades, Smooth Pursuit, and Optokinetic Nystagmus

  2009cited by this paper
• Donepezil treatment of patients with MCI

  2009cited by this paper
• Cerebellar vermal volumes and behavioral correlates in children with autism spectrum disorder.

  2009cited by this paper
• Signal Processing and Distribution in Cortical‐Brainstem Pathways for Smooth Pursuit Eye Movements

  2009cited by this paper
• Lateralized response timing deficits in autism.

  2009cited by this paper
• Differential effects on white-matter systems in high-functioning autism and Asperger's syndrome

  2009cited by this paper
• Neuropsychological profile of autism and the broad autism phenotype.

  2009cited by this paper
• No differences in MR-based volumetry between 2- and 7-year-old children with autism spectrum disorder and developmental delay.

  2009cited by this paper
• Impaired inhibitory control is associated with higher-order repetitive behaviors in autism spectrum disorders

  2009cited by this paper
• Response monitoring, repetitive behaviour and anterior cingulate abnormalities in autism spectrum disorders (ASD)

  2008cited by this paper
• Neurophysiology and neuroanatomy of smooth pursuit: lesion studies.

  2008cited by this paper
• Cortico-striatal representation of time in animals and humans.

  2008cited by this paper
• Quantitative magnetic resonance image analysis of the cerebellum in macrocephalic and normocephalic children and adults with autism

  2008cited by this paper
• Defining key features of the broad autism phenotype: A comparison across parents of multiple‐ and single‐incidence autism families

  2008cited by this paper
• Randomized double‐blind placebo‐controlled donepezil augmentation in antidepressant‐treated elderly patients with depression and cognitive impairment: a pilot study

  2008cited by this paper
• A double blind, placebo‐controlled pilot study of galantamine augmentation of antidepressant treatment in older adults with major depression

  2008cited by this paper
• Distinct face-processing strategies in parents of autistic children.

  2008cited by this paper
• Patterns of visual sensory and sensorimotor abnormalities in autism vary in relation to history of early language delay

  2008cited by this paper
• Altered cerebellar feedback projections in Asperger syndrome

  2008cited by this paper
• Cerebellar Purkinje Cells are Reduced in a Subpopulation of Autistic Brains: A Stereological Experiment Using Calbindin-D28k

  2008cited by this paper
• Effects of second-generation antipsychotic medication on smooth pursuit performance in antipsychotic-naive schizophrenia.

  2008cited by this paper
• Maturation of executive function in autism.

  2007cited by this paper
• Reduced saccadic resilience and impaired saccadic adaptation due to cerebellar disease

  2007cited by this paper
• Inhibitory control in high-functioning autism: decreased activation and underconnectivity in inhibition networks.

  2007cited by this paper
• Effect of rivastigmine on delay to diagnosis of Alzheimer's disease from mild cognitive impairment: the InDDEx study.

  2007cited by this paper
• Gaze-fixation, brain activation, and amygdala volume in unaffected siblings of individuals with autism.

  2007cited by this paper
• Atypical involvement of frontostriatal systems during sensorimotor control in autism.

  2007cited by this paper
• Shared executive dysfunctions in unaffected relatives of patients with autism and obsessive-compulsive disorder

  2007cited by this paper
• Social-cognition and the broad autism phenotype: identifying genetically meaningful phenotypes.

  2007cited by this paper
• Spatial Working Memory Deficits in Autism

  2007cited by this paper
• Cognitive and symptom profiles in Asperger’s syndrome and high‐functioning autism

  2007cited by this paper
• Autistic social impairment in the siblings of children with pervasive developmental disorders.

  2006cited by this paper
• Familial aggregation of eye-tracking endophenotypes in families of schizophrenic patients.

  2006cited by this paper
• Longitudinal studies of antisaccades in antipsychotic-naive first-episode schizophrenia

  2006cited by this paper
• Neural correlates of executive function in autistic spectrum disorders.

  2006cited by this paper
• Head circumference and height in autism: A study by the collaborative program of excellence in autism

  2006cited by this paper
• Neuroanatomic observations of the brain in autism: a review and future directions

  2005cited by this paper
• Structural white matter deficits in high-functioning individuals with autistic spectrum disorder: a voxel-based investigation

  2005cited by this paper
• Verbal and Spatial Working Memory in Autism

  2005cited by this paper
• Functional neuroanatomy of anticipatory behavior: dissociation between sensory-driven and memory-driven systems.

  2005cited by this paper
• Abnormalities in visually guided saccades suggest corticofugal dysregulation in never-treated schizophrenia.

  2005cited by this paper
• Subtle Executive Impairment in Children with Autism and Children with ADHD

  2005cited by this paper
• Support for the homeobox transcription factor gene ENGRAILED 2 as an autism spectrum disorder susceptibility locus.

  2005cited by this paper
• Neurocognitive and electrophysiological evidence of altered face processing in parents of children with autism: Implications for a model of abnormal development of social brain circuitry in autism

  2005cited by this paper
• Oculomotor abnormalities parallel cerebellar histopathology in autism

  2004cited by this paper
• Defining the Intellectual Profile of Asperger Syndrome: Comparison with High-Functioning Autism

  2004cited by this paper
• Maturation of cognitive processes from late childhood to adulthood.

  2004cited by this paper
• Association of the homeobox transcription factor, ENGRAILED 2, 3, with autism spectrum disorder

  2004cited by this paper
• Pursuit eye movement deficits in autism.

  2004cited by this paper
• The Social Communication Questionnaire Manual

  2003cited by this paper
• Abnormal Brain Lateralization in High-Functioning Autism

  2003cited by this paper
• Brain anatomy and sensorimotor gating in Asperger's syndrome.

  2002cited by this paper
• Eye Movement Abnormality Suggestive of a Spatial Working Memory Deficit Is Present in Parents of Autistic Probands

  2002cited by this paper
• Purkinje Cell Size Is Reduced in Cerebellum of Patients with Autism

  2002cited by this paper
• Abnormal asymmetry in language association cortex in autism

  2002cited by this paper
• Deficits in the initiation of eye movements in the absence of a visual target in adolescents with high functioning autism.

  2002cited by this paper
• Saccadic dysmetria following inactivation of the primate fastigial oculomotor region.

  2002cited by this paper
• Neocortical system abnormalities in autism: An fMRI study of spatial working memory

  2002cited by this paper
• Dysregulation of Reelin and Bcl-2 Proteins in Autistic Cerebellum

  2001cited by this paper
• The 2nd to 4th digit ratio and autism

  2001cited by this paper
• The Autism-Spectrum Quotient (AQ): Evidence from Asperger Syndrome/High-Functioning Autism, Malesand Females, Scientists and Mathematicians

  2001cited by this paper
• The Autism Diagnostic Observation Schedule—Generic: A Standard Measure of Social and Communication Deficits Associated with the Spectrum of Autism

  2000cited by this paper
• Variable expression of the autism broader phenotype: findings from extended pedigrees.

  2000cited by this paper
• Macrocephaly in autism and other pervasive developmental disorders

  2000cited by this paper
• Pursuit tracking impairments in schizophrenia and mood disorders: step-ramp studies with unmedicated patients.

  1999cited by this paper
• Brain Mapping of Language and Auditory Perception in High-Functioning Autistic Adults: A PET Study

  1999cited by this paper
• Heterogeneity and the genetics of autism.

  1999cited by this paper
• Towards a cognitive phenotype for autism: increased prevalence of executive dysfunction and superior spatial span amongst siblings of children with autism.

  1999cited by this paper
• Oculomotor evidence for neocortical systems but not cerebellar dysfunction in autism

  1999cited by this paper
• A clinicopathological study of autism.

  1998cited by this paper
• A longitudinal analysis of eye tracking dysfunction and attention in recent-onset schizophrenia.

  1998cited by this paper
• Children's Yale-Brown Obsessive Compulsive Scale: reliability and validity.

  1997cited by this paper
• Executive function in parents of children with autism

  1997cited by this paper
• Vestibular Bibliography

  1996cited by this paper
• Neuropharmacology of timing and time perception.

  1996cited by this paper
• Positron emission tomography study of voluntary saccadic eye movements and spatial working memory.

  1996cited by this paper
• Hand preference and hand skill in children with autism

  1996cited by this paper
• A broader phenotype of autism: the clinical spectrum in twins.

  1996cited by this paper
• Validity and neuropsychological characterization of Asperger syndrome: convergence with nonverbal learning disabilities syndrome.

  1995cited by this paper
• Latent-class analysis of recurrence risks for complex phenotypes with selection and measurement error: a twin and family history study of autism.

  1995cited by this paper
• Abnormality of smooth pursuit eye movement initiation: specificity to the schizophrenia spectrum?

  1995cited by this paper
• Concordance of smooth pursuit and saccadic measures in normal monozygotic twin pairs.

  1994cited by this paper
• A case-control family history study of autism.

  1994cited by this paper
• Eye tracking and schizophrenia: a selective review.

  1994cited by this paper
• Autism Diagnostic Interview-Revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders

  1994cited by this paper
• Rating chronic medical illness burden in geropsychiatric practice and research: application of the Cumulative Illness Rating Scale.

  1992cited by this paper
• Facial emotion discrimination: I. Task construction and behavioral findings in normal subjects.

  1992cited by this paper
• Social language use in parents of autistic individuals

  1992cited by this paper
• Platelet serotonin, a possible marker for familial autism

  1991cited by this paper
• Effects of fastigial stimulation upon visually-directed saccades in macaque monkeys.

  1991cited by this paper
• The Yale-Brown Obsessive Compulsive Scale. I. Development, use, and reliability.

  1989cited by this paper
• The Yale-Brown Obsessive Compulsive Scale: I. Development, Use, and Reliability

  1989cited by this paper
• Hypoplasia of cerebellar vermal lobules VI and VII in autism.

  1988cited by this paper
• Oculomotor findings in autistic children

  1988cited by this paper
• Head circumference reference data: birth to 18 years.

  1987cited by this paper
• Lower Purkinje cell counts in the cerebella of four autistic subjects: initial findings of the UCLA-NSAC Autopsy Research Report.

  1986cited by this paper
• Handedness patterns in autism suggest subtypes

  1986cited by this paper

• Sensorimotor Behavior in Individuals With Autism Spectrum Disorder and Their Unaffected Biological Parents

  2025cites this paper
• The relationship between the maternal consumption of barberry, saffron, pickled vegetables, and tea and the odds of congenital anomalies in Iranian children under 10 years of age: A case-control study

  2025cites this paper
• Simple Executive Function as an endophenotype of autism-ADHD, and differing associations between simple versus complex Executive Functions and autism/ADHD traits

  2025cites this paper
• Oculomotor Function in Children and Adolescents with Autism, ADHD or Co-occurring Autism and ADHD.

  2025cites this paper
• Sensorimotor Behavior in Individuals with Autism Spectrum Disorder and Their Unaffected Biological Parents

  2023cites this paper
• Neurocognitive and self-reported psychosocial and behavioral functioning in siblings of individuals with neurodevelopmental conditions: a study using remote self-administered testing

  2023cites this paper
• Endophenotype trait domains for advancing gene discovery in autism spectrum disorder

  2023cites this paper
• Combined Gait and Grasping in Autistic and Non-Autistic Youths

  2022cites this paper
• Aspects of Mental Health among Parents of Children with Developmental Disorders

  2022cites this paper
• Cerebellar Volumes and Sensorimotor Behavior in Autism Spectrum Disorder

  2022cites this paper
• Associations Among Daily Living Skills, Motor, and Sensory Difficulties in Autistic and Nonautistic Children.

  2022cites this paper
• Eye-tracker-based Evaluation of Saccadic Deficits in Young Children with Developmental Disorders

  2021cites this paper
• Initial action output and feedback-guided motor behaviors in autism spectrum disorder

  2021cites this paper
• Neurobiological and behavioural outcomes of biofeedback-based training in autism: a randomized controlled trial

  2021cites this paper
• Distinct Sensorimotor Feedforward and Feedback Deficits Vary with Age in Individuals with Autism Spectrum disorder

  2021cites this paper
• Individual differences in autistic traits are associated with serotonin transporter gene polymorphism through medial prefrontal function: a study using NIRS.

  2021cites this paper
• Understanding Social Communication Differences in ASD and First-Degree Relatives

  2021cites this paper
• Visuomotor brain network activation and functional connectivity among individuals with autism spectrum disorder

  2021cites this paper
• Brief Report: Associations Between Cognitive Control Processes and Traits of Autism Spectrum Disorder (ASD), attention-Deficit/Hyperactivity Disorder (ADHD) and Anxiety in Children at Elevated and Typical Familial Likelihood for ASD

  2020cites this paper
• Brief Report: Associations Between Cognitive Control Processes and Traits of Autism Spectrum Disorder (ASD), attention-Deficit/Hyperactivity Disorder (ADHD) and Anxiety in Children at Elevated and Typical Familial Likelihood for ASD

  2020cites this paper
• Motor functioning in developmental psychopathology: A review of autism as an example context.

  2020cites this paper
• IQ and Sensory Symptom Severity Best Predict Motor Ability in Children With and Without Autism Spectrum Disorder

  2020cites this paper
• Autistic traits are associated with the functional connectivity of between—but not within—attention systems in the general population

  2020cites this paper
• Reduced Proactive Control Processes Associated With Behavioral Response Inhibition Deficits in Autism Spectrum Disorder

  2020cites this paper
• Differentiating early Parkinson's disease and multiple system atrophy with parkinsonism by saccade velocity profiles.

  2019cites this paper
• Familiality of behavioral flexibility and response inhibition deficits in autism spectrum disorder (ASD)

  2019cites this paper
• Bimanual Reach to Grasp Movements in Youth With and Without Autism Spectrum Disorder

  2019cites this paper
• Understanding Social Communication Differences in Autism Spectrum Disorder and First-Degree Relatives: A Study of Looking and Speaking

  2019cites this paper
• Motor Memory Deficits Contribute to Motor Impairments in Autism Spectrum Disorder

  2019cites this paper
• Standing Balance on Unsteady Surfaces in Children on the Autism Spectrum: The Effects of IQ.

  2018cites this paper
• The neurological examination in adults with autism spectrum conditions: a pilot study

  2018cites this paper
• Saccadic eye movements in adults with high-functioning autism spectrum disorder

  2018cites this paper
• Cognitive mechanisms of inhibitory control deficits in autism spectrum disorder

  2018cites this paper
• Eye movements, sensorimotor adaptation and cerebellar‐dependent learning in autism: toward potential biomarkers and subphenotypes

  2018cites this paper
• Resting-state Gamma-band EEG Abnormalities in Autism*

  2018cites this paper
• Autism Spectrum Symptoms in Children and Adolescents with Obsessive Compulsive Disorder and Their Mothers.

  2017cites this paper
• Toward a conceptual framework for early brain and behavior development in autism

  2017cites this paper
• Executive functioning and local‐global visual processing: candidate endophenotypes for autism spectrum disorder?

  2017cites this paper
• What is the Nature of Motor Impairments in Autism, Are They Diagnostically Useful, and What Are the Implications for Intervention?

  2017cites this paper
• The impact of response complexity and cue modality for choice eye-hand coordination movements in typically developing individuals

  2017cites this paper
• Cross-Disorder Cognitive Impairments in Youth Referred for Neuropsychiatric Evaluation

  2017cites this paper
• Distinguishing spinocerebellar ataxia with pure cerebellar manifestation from multiple system atrophy (MSA-C) through saccade profiles.

  2017cites this paper
• Motor Memory Deficits Contribute to Motor Impairments in Autism Spectrum Disorder

  2016cites this paper
• Association of Autism Spectrum Disorder with Obsessive-Compulsive and Attention-Deficit/Hyperactivity Traits and Response Inhibition in a Community Sample

  2016cites this paper
• So close yet so far: Motor anomalies impacting on social functioning in autism spectrum disorder.

  2016cites this paper
• FeedforwardandFeedbackMotorControlAbnormalities ImplicateCerebellarDysfunctionsinAutismSpectrum Disorder

  2015cites this paper
• Investigating the neurobiological and cognitive features of anorexia nervosa

  2015cites this paper
• Autism's anatomy: A dissection of the structure and development of a psychiatric concept

  2015influential citation
• Accelerated time course of saccadic inhibition of return in individuals with autism spectrum disorders

  2015cites this paper
• Individuals with autism spectrum disorder show abnormalities during initial and subsequent phases of precision gripping.

  2015cites this paper
• Feedforward and Feedback Motor Control Abnormalities Implicate Cerebellar Dysfunctions in Autism Spectrum Disorder

  2015cites this paper
• Amygdala lesions do not compromise the cortical network for false-belief reasoning

  2015cites this paper
• Sensorimotor dysfunctions as primary features of autism spectrum disorders

  2015cites this paper
• The role of cerebellar circuitry alterations in the pathophysiology of autism spectrum disorders

  2015influential citation
• Gamma-band abnormalities as markers of autism spectrum disorders

  2014influential citation
• The Broader Autism Phenotype

  2014cites this paper
• Funkcje wykonawcze a symptomy zaburzeń ze spektrum autyzmu – przegląd literatury.

  2014cites this paper
• Saccadic eye movement abnormalities in autism spectrum disorder indicate dysfunctions in cerebellum and brainstem

  2014influential citation
• Implicit learning in individuals with autism spectrum disorders: a meta-analysis

  2014cites this paper
• Decreased left perisylvian GABA concentration in children with autism and unaffected siblings

  2014cites this paper
• γ-band abnormalities as markers of autism spectrum disorders.

  2014cites this paper
• Neural correlate of autistic-like traits and a common allele in the oxytocin receptor gene.

  2014cites this paper
• Sources of variation in developmental language disorders: evidence from eye-tracking studies of sentence production

  2014cites this paper
• Imaging the Neural Correlates of Behavioral and Cognitive Shifts in Autism

  2014cites this paper
• Prospective examination of visual attention during play in infants at high-risk for autism spectrum disorder: a longitudinal study from 6 to 36 months of age.

  2013cites this paper
• Deficits in volitional oculomotor control align with language status in autism spectrum disorders.

  2013cites this paper
• Saccade Adaptation Abnormalities Implicate Dysfunction of Cerebellar-Dependent Learning Mechanisms in Autism Spectrum Disorders (ASD)

  2013cites this paper
• Lifetime and current mood and anxiety disorders in short-term and long-term abstinent alcoholics.

  2013cites this paper
• Chapter 1 – Autism Heterogeneity

  2013cites this paper
• Autism spectrum disorder and the cerebellum.

  2013cites this paper
• Autism Symptom Heterogeneity Exists in Family Members

  2013cites this paper
• Manuscript to be submitted for an original article in Social Cognitive and Affective Neuroscience)

  2013cites this paper
• Parents Speak: An Ethnographic Study of Autism Parents

  2013cites this paper
• White matter microstructure and atypical visual orienting in 7-month-olds at risk for autism.

  2013cites this paper
• Autism in flux: a history of the concept from Leo Kanner to DSM-5

  2013cites this paper
• The Broader Autism Phenotype in the Parents of Children With Autism Spectrum Conditions

  2012cites this paper
• Rare inherited A2BP1 deletion in a proband with autism and developmental hemiparesis

  2012cites this paper
• What the Future Holds for the Study of Saccades

  2012cites this paper
• Predicting the diagnosis of autism spectrum disorder using gene pathway analysis

  2012cites this paper
• Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy

  2012cites this paper
• Consensus Paper: Pathological Role of the Cerebellum in Autism

  2012cites this paper
• Pathophysiological distortions in time perception and timed performance.

  2012cites this paper
• Obsessive-Compulsive Disorders or Not: Differential Diagnosis of Repetitive Behaviors Among Individuals with Intellectual and Developmental Disorders

  2011cites this paper
• Autistic Traits Below the Clinical Threshold: Re-examining the Broader Autism Phenotype in the 21st Century

  2011influential citation
• A review on cognitive and brain endophenotypes that may be common in autism spectrum disorder and attention-deficit/hyperactivity disorder and facilitate the search for pleiotropic genes.

  2011cites this paper
• Orienting to Object Exploration in Infancy: Examining the Genetic Liability of Autism

  2011cites this paper
• Transient and steady-state auditory gamma-band responses in first-degree relatives of people with autism spectrum disorder

  2011cites this paper
• Neuroscience and Biobehavioral Reviews so Close yet so Far: Motor Anomalies Impacting on Social Functioning in Autism Spectrum Disorder

  year unknowncites this paper