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Cardiotoxicity Induced by Anticancer Drugs—the Role of Biomarkers

G. Biasillo,C. Cipolla,D. Cardinale

Published 2017 in Unknown venue

ABSTRACT

Anticancer therapy-induced cardiotoxicity still remains a serious problem, strongly affecting both quality of life and overall survival of oncologic patients. The most effective approach for minimizing cardiotoxicity is its early detection and prompt prophylactic treatment initiation. According to the current standard for monitoring cardiac function, cardiotoxicity is usually detected only when a functional impairment has already occurred, precluding any chance of preventing its development. Over the last decade, however, measurement of serum cardio-specific biomarkers has emerged, resulting in a cost-effective diagnostic tool for early identification of patients more prone to developing cardiotoxicity, in whom a preventive pharmacological strategy and a closer cardiac monitoring are of crucial importance.

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