Localization of the MEN1 gene to a small region within chromosome 11q13 by deletion mapping in tumors.

No abstract is available for this paper.

• Publication year

  1990

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  1990-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1073/PNAS.87.5.1968PMID 1968641PMCID PMC53606
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Identification of the cystic fibrosis gene: genetic analysis.

  1989cited by this paper
• Familial Wiedemann-Beckwith syndrome and a second Wilms tumor locus both map to 11p15.5.

  1989cited by this paper
• Deletion mapping in human renal cell carcinoma.

  1989cited by this paper
• Identification of the cystic fibrosis gene: chromosome walking and jumping.

  1989cited by this paper
• Clonality of parathyroid tumors in familial multiple endocrine neoplasia type 1.

  1989cited by this paper
• Localization of the genetic defect in multiple endocrine neoplasia type 1 within a small region of chromosome 11.

  1989cited by this paper
• Genetic linkage of Beckwith-Wiedemann syndrome to 11p15.

  1989cited by this paper
• Association of parathyroid tumors in multiple endocrine neoplasia type 1 with loss of alleles on chromosome 11.

  1989cited by this paper
• Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA.

  1989cited by this paper
• Cancer. Gene losses in human tumours.

  1988cited by this paper
• Prediction of the risk of hereditary retinoblastoma, using DNA polymorphisms within the retinoblastoma gene.

  1988cited by this paper
• Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells.

  1988cited by this paper
• Monoclonality and abnormal parathyroid hormone genes in parathyroid adenomas.

  1988cited by this paper
• Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma

  1988cited by this paper
• Deletion mapping of a locus on human chromosome 22 involved in the oncogenesis of meningioma.

  1987cited by this paper
• Chromosomal localization of the human rhabdomyosarcoma locus by mitotic recombination mapping

  1987cited by this paper
• Genetic linkage of bilateral acoustic neurofibromatosis to a DNA marker on chromosome 22

  1987cited by this paper
• Complete cloning of the Duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals.

  1987cited by this paper
• The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity

  1987cited by this paper
• Report of the committee on human gene mapping by recombinant DNA techniques.

  1987cited by this paper
• Structural evidence for the authenticity of the human retinoblastoma gene.

  1987cited by this paper
• Common pathogenetic mechanism for three tumor types in bilateral acoustic neurofibromatosis.

  1987cited by this paper
• Familial multiple endocrine neoplasia type I: a new look at pathophysiology.

  1987cited by this paper
• Human retinoblastoma susceptibility gene: cloning, identification, and sequence

  1987cited by this paper
• A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

  1986cited by this paper
• Molecular detection of deletions involving band q14 of chromosome 13 in retinoblastomas.

  1986cited by this paper
• Loss of genes on chromosome 22 in tumorigenesis of human acoustic neuroma

  1986cited by this paper
• Osteosarcoma and retinoblastoma: a shared chromosomal mechanism revealing recessive predisposition.

  1985cited by this paper
• Loss of heterozygosity in three embryonal tumours suggests a common pathogenetic mechanism

  1985cited by this paper
• Genetic origin of mutations predisposing to retinoblastoma.

  1985cited by this paper
• Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

  1983cited by this paper
• Multiple endocrine neoplasia type 1.

  1980cited by this paper
• Mutation and cancer: statistical study of retinoblastoma.

  1971cited by this paper

• Approach to the Patient with Primary Hyperparathyroidism in Multiple Endocrine Neoplasia Type 1.

  2025cites this paper
• Genotype-histotype-phenotype correlations in hyperinsulinemic hypoglycemia.

  2024cites this paper
• Molecular and Clinical Spectrum of Primary Hyperparathyroidism.

  2023cites this paper
• Pancreatic Neuroendocrine Tumors: Molecular Mechanisms and Therapeutic Targets

  2021cites this paper
• Molecular basis of parathyroid hormone overexpression

  2020cites this paper
• Insights into pituitary tumorigenesis: from Sanger sequencing to next-generation sequencing and beyond

  2019cites this paper
• First Case of Mature Teratoma and Yolk Sac Testis Tumor Associated to Inherited MEN-1 Syndrome

  2019cites this paper
• Molecular genetic insights into sporadic primary hyperparathyroidism.

  2019cites this paper
• Multiple Endocrine Neoplasia Syndromes from Genetic and Epigenetic Perspectives

  2018cites this paper
• Happy 20th anniversary MEN1: from positional cloning to gene function restoration.

  2017influential citation
• Molecular Genetics of MEN1-Related Neuroendocrine Tumors

  2017cites this paper
• Molecular Genetics of Gastroenteropancreatic Neuroendocrine Tumours

  2017cites this paper
• Classification, Pathobiology, Molecular Markers, and Intraoperative Pathology

  2017cites this paper
• Genetic Syndromes with Pancreatic Manifestations.

  2016cites this paper
• Chapter 148 – Multiple Endocrine Neoplasia Type 1

  2016cites this paper
• Chapter 4 – Applications of Genetics in Endocrinology

  2016cites this paper
• MAJOR MOLECULAR GENETIC DRIVERS IN SPORADIC PRIMARY HYPERPARATHYROIDISM.

  2016cites this paper
• NEOPLASIAS ENDOCRINAS MÚLTIPLES EN UN RECIÉN NACIDO

  2015cites this paper
• Molecular Basis of Primary Hyperparathyroidism

  2015cites this paper
• Neuroendocrine tumours.

  2014cites this paper
• Thoracic and duodenopancreatic neuroendocrine tumors in multiple endocrine neoplasia type 1: natural history and function of menin in tumorigenesis.

  2014cites this paper
• Genetic and epigenetic mutations of tumor suppressive genes in sporadic pituitary adenoma.

  2014cites this paper
• Parathyroid hyperplasia shown on (99m)Tc-HYNIC-TOC scan.

  2013cites this paper
• Shortness: an unknown phenotype of multiple endocrine neoplasia type 1.

  2013cites this paper
• Ligand-Directed AAVP to Deliver a Therapeutic Transgene to Neuroendocrine Tumors of the Pancreas

  2013cites this paper
• Clinical and immunohistochemical studies of small bowel carcinoid tumours

  2011cites this paper
• Doctor of Nursing Practice portfolio of Christine Yedinak

  2011cites this paper
• MEN1 (multiple endocrine neoplasia I)

  2011cites this paper
• Growth hormone-secreting adenomas: pathology and cell biology.

  2010cites this paper
• Transmissible Genes Induced Chromosome-type Aberrations in the Lymphocytes of Multiple Endocrine Neoplasia Type 1 and Type 2A (MEN1 and MEN2A) Patients

  2010cites this paper
• 11 – Endocrine Neoplasia

  2010cites this paper
• Multiple endocrine neoplasia type 1 (MEN1).

  2010cites this paper
• Nonneoplastic and Neoplastic Pituitary Diseases

  2010cites this paper
• The evolving field of tyrosine kinase inhibitors in the treatment of endocrine tumors.

  2010cites this paper
• Endocrine cancer predisposition syndromes: hereditary paraganglioma, multiple endocrine neoplasia type 1, multiple endocrine neoplasia type 2, and hereditary thyroid cancer.

  2010cites this paper
• Familial pituitary tumor syndromes

  2009cites this paper
• Cushing's disease.

  2009cites this paper
• Deregulation of anti-Mullerian hormone/BMP and transforming growth factor-beta pathways in Leydig cell lesions developed in male heterozygous multiple endocrine neoplasia type 1 mutant mice.

  2008cites this paper
• Chapter 62 – Multiple Endocrine Neoplasia Type 1

  2008cites this paper
• Blocking Vascular Endothelial Growth Factor-A Inhibits the Growth of Pituitary Adenomas and Lowers Serum Prolactin Level in a Mouse Model of Multiple Endocrine Neoplasia Type 1

  2008cites this paper
• Molecular Basis of PTH Overexpression

  2008cites this paper
• The genetic ascertainment of multiple endocrine neoplasia type 1 syndrome by ancient DNA analysis

  2008cites this paper
• Multiple endocrine neoplasia type 1 (MEN1): analysis of 1336 mutations reported in the first decade following identification of the gene

  2008cites this paper
• Reconstituted expression of menin in Men1-deficient mouse Leydig tumour cells induces cell cycle arrest and apoptosis.

  2007cites this paper
• Neurosurgical oncology: neoplasms of the brain and meninges

  2007cites this paper
• BlockingVascular Endothelial Growth Factor-A Inhibits the Growth of PituitaryAdenomas and Lowers Serum Prolactin Level in a MouseModel of Multiple Endocrine NeoplasiaType 1

  2007cites this paper
• A Family Mutation of MEN1 with a Novel Germline Missense and Benign Polymorphisms

  2006cites this paper
• ACTH-secreting thymic carcinoid associated with multiple endocrine neoplasia type 1.

  2006cites this paper
• Microadenomatosis of the Endocrine Pancreas in Patients With and Without the Multiple Endocrine Neoplasia Type 1 Syndrome

  2006cites this paper
• Allelic deletion of the MEN1 gene in duodenal gastrin and somatostatin cell neoplasms and their precursor lesions

  2006cites this paper
• Mutation of the MEN IN Gene in Sporadic Pancreatic Endocrine Tumors 1

  2006cites this paper
• Molecular basis of hyperparathyroidism

  2006cites this paper
• Microsatellite instability and loss of heterozygosity at the MEN1 locus in lung carcinoid tumors: a novel approach using real-time PCR with melting curve analysis in histopathologic material.

  2006cites this paper
• From gene mutation to gene expression : studies on multiple endocrine neoplasia type 1 and vascular endothelial growth factors

  2006influential citation
• Hyperinsulinemic hypoglycemia due to adult nesidioblastosis in insulin-dependent diabetes.

  2006cites this paper
• Cells in focus Cells of the anterior pituitary

  2006cites this paper
• PITUITARY ADENOMAS IN CHILDHOOD: DEVELOPMENT AND DIAGNOSIS

  2006cites this paper
• New splicing mutation of MEN1 gene affecting the translocation of menin to the nucleous

  2006cites this paper
• Advances in Brief Mutation of the Multiple Endocrine Neoplasia Type 1 Gene in Noni umiliai , Malignant Tumors of the Endocrine Pancreas 1

  2006cites this paper
• Cells of the anterior pituitary.

  2006cites this paper
• Molecular Genetic Abnormalities in Sporadic Hyperparathyroidism

  2005cites this paper
• Genetics of pituitary adenomas: current theories and future implications.

  2005cites this paper
• Common genetic changes in hereditary and sporadic pituitary adenomas detected by comparative genomic hybridization

  2005cites this paper
• Precursor lesions in patients with multiple endocrine neoplasia type 1-associated duodenal gastrinomas.

  2005cites this paper
• The molecular genetics of gastroenteropancreatic neuroendocrine tumors

  2005cites this paper
• Genome-wide screening of loss of heterozygosity in human midgut carcinoid tumors with fluorescent technique

  2004cites this paper
• Molecular Biology of Pituitary Tumors

  2004cites this paper
• CURRENT DATA ON THE ETIOPATHOGENESIS OF PITUITARY ADENOMAS

  2004cites this paper
• Multiple endocrine neoplasia type 1 (MEN 1) revisited

  2004cites this paper
• Pancreatic Disease

  2004cites this paper
• GENOME-WIDE SCREENING OF LOSS OF HETEROZYGOSITY IN HUMAN MIDGUT CARCINOID TUMORS WITH FLUORESCENT TECHNIQUE

  2004cites this paper
• GI Hormone Producing Tumours: Syndromes and Treatment Options

  2004cites this paper
• Novel somatic MEN1 gene alterations in sporadic primary hyperparathyroidism and correlation with clinical characteristics

  2004cites this paper
• Korrelation von immunhistochemischen Tumormarkern mit klinischen Befunden und einer berechneten Tumorwachstumsgeschwindigkeit bei nichthormonsezernierenden Hypophysenadenomen

  2004cites this paper
• New gene in the homologous human 11q13–q14 and mouse 7F chromosomal regions

  2004cites this paper
• Prediction of recurrence of nonfunctioning pituitary tumours by loss of heterozygosity analysis

  2004cites this paper
• Pathogenesis of Pituitary Adenomas

  2003cites this paper
• Multiple Endocrine Neoplasia Types 1, 2a, and 2b

  2003cites this paper
• In situ RNA-RNA hybridisation of phospholipase C beta 3 shows lack of expression in neuroendocrine tumours.

  2003cites this paper
• The management of non-functioning pituitary adenomas.

  2003cites this paper
• Heterozygous Men1 mutant mice develop a range of endocrine tumors mimicking multiple endocrine neoplasia type 1.

  2003cites this paper
• Molecular defects in the pathogenesis of pituitary tumours.

  2003cites this paper
• Carcinoid A Comprehensive Review

  2003cites this paper
• Genetic ablation of the tumor suppressor menin causes lethality at mid-gestation with defects in multiple organs.

  2003cites this paper
• Multiple Endocrine Neoplasia Type 1 and Lipomas

  2002cites this paper
• HRPT2, encoding parafibromin, is mutated in hyperparathyroidism–jaw tumor syndrome

  2002cites this paper
• Chapter 58 – Multiple Endocrine Neoplasia Type 1

  2002cites this paper
• Molecular pathogenesis of primary hyperparathyroidism.

  2002cites this paper
• Familial Adenomatous Polyposis Associated With Multiple Endocrine Neoplasia Type 1-Related Tumors and Thyroid Carcinoma: A Case Report With Clinicopathologic and Molecular Analyses

  2002influential citation
• Mutational analysis of Portuguese families with multiple endocrine neoplasia type 1 reveals large germline deletions

  2002cites this paper
• Premalignant conditions of the pancreas

  2002cites this paper
• Etiology of Pituitary Tumours

  2002cites this paper
• The pathogenesis of pituitary tumours

  2002cites this paper
• Identification of candidate liver tumor suppressor genes from human 11p11.2‐p12

  2002cites this paper
• Atlas of Genetics and Cytogenetics in Oncology and Haematology

  2002cites this paper
• Determination of allelic deletion of multiple endocrine neoplasm type 1 (MEN1) gene in acute myeloid leukemia (AML) by application of FISH-TSA technique.

  2002cites this paper
• Germline mutation profile of MEN1 in multiple endocrine neoplasia type 1: search for correlation between phenotype and the functional domains of the MEN1 protein

  2002cites this paper
• Increased menin expression in sporadic pituitary adenomas

  2002cites this paper
• MEN1 gene alterations do not correlate with the phenotype of sporadic primary hyperparathyroidism

  2002cites this paper
• ACTH Secreting Pituitary Adenomas

  2002cites this paper