Global elimination of trachoma: How frequently should we administer mass chemotherapy?

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Nature Medicine

• Publication date

  1999-05-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1038/8451PMID 10229236
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Reliability of clinical diagnosis in identifying infectious trachoma in a low-prevalence area of Nepal.

  1999cited by this paper
• Azithromycin for control of trachoma.

  1999cited by this paper
• Doxycycline and Azithromycin for Prevention of Chlamydial Persistence or Recurrence One Month After Treatment in Women: A Use‐Effectiveness Study in Public Health Settings

  1998cited by this paper
• Predicting and preventing the emergence of antiviral drug resistance in HSV-2

  1998cited by this paper
• Single-dose azithromycin for Chlamydia in pregnant women.

  1998cited by this paper
• Quantifying the intrinsic transmission dynamics of tuberculosis.

  1998cited by this paper
• Note: Kinetics of Chlamydia trachomatis Clearance in Patients With Azithromycin, as Assessed by First Void Urine Testing by PCR and Transcription‐Mediated Amplification

  1998cited by this paper
• Uncertainty and sensitivity analysis of the basic reproductive rate. Tuberculosis as an example.

  1997cited by this paper
• Trachoma: the forgotten cause of blindness.

  1997cited by this paper
• Severe disease in children with trachoma is associated with persistent Chlamydia trachomatis infection.

  1997cited by this paper
• Doxycycline Compared with Azithromycin for Treating Women with Genital Chlamydia trachomatis Infections: An Incremental Cost-Effectiveness Analysis

  1996cited by this paper
• Models for Infectious Human Diseases: Modeling heterogeneous mixing in infectious disease dynamics

  1996cited by this paper
• Chlamydial cervicitis and urethritis: single dose treatment compared with doxycycline for seven days in community based practises.

  1996cited by this paper
• Control Strategies for Tuberculosis Epidemics: New Models for Old Problems

  1996cited by this paper
• The Treatment of Non-Gonococcal Urethritis with Single Dose Oral Azithromycin

  1995cited by this paper
• Azithromycin for empirical treatment of the nongonococcal urethritis syndrome in men. A randomized double-blind study.

  1995cited by this paper
• Extent and kinetics of genetic change in the omp1 gene of Chlamydia trachomatis in two villages with endemic trachoma.

  1995cited by this paper
• The intrinsic transmission dynamics of tuberculosis epidemics

  1995cited by this paper
• Age and Clinical Immunity to Infections With Chlamydia trachomatis

  1994cited by this paper
• Single Dose Azithromycin Treatment of Gonorrhea and Infections Caused by C. trachomatis and U. urealyticum in Men

  1994cited by this paper
• Sensitivity and Uncertainty Analysis of Complex Models of Disease Transmission: an HIV Model, as an Example

  1994cited by this paper
• Molecular epidemiology of trachoma in a Gambian village.

  1994cited by this paper
• Randomised controlled trial of single-dose azithromycin in treatment of trachoma.

  1993cited by this paper
• Nonocular Chlamydia infection and risk of ocular reinfection after mass treatment in a trachoma hyperendemic area.

  1993cited by this paper
• Drugs, sex and HIV: a mathematical model for New York City.

  1991cited by this paper
• Longitudinal study of the microbiology of endemic trachoma

  1991cited by this paper
• Infectious Diseases of Humans: Dynamics and Control

  1991cited by this paper
• The epidemiology of trachoma in central Tanzania.

  1991cited by this paper
• The World Health Organization's programme for the prevention of blindness.

  1990cited by this paper
• Persisting inapparent chlamydial infection in a trachoma endemic community in The Gambia.

  1990cited by this paper
• Trachoma and blindness in the Nile Delta: current patterns and projections for the future in the rural Egyptian population.

  1989cited by this paper
• Analysis of the household distribution of trachoma in a Gambian village using a Monte Carlo simulation procedure.

  1989cited by this paper
• The epidemiology of infection in trachoma.

  1989cited by this paper
• Networks of sexual contacts: implications for the pattern of spread of HIV

  1989cited by this paper
• The epidemiology of trachoma in southern Malawi.

  1988cited by this paper
• Fifteen-month follow-up study of women infected with Chlamydia trachomatis.

  1979cited by this paper
• Human chlamydial infections

  1978cited by this paper
• Severe endemic trachoma in Tunisia.

  1976cited by this paper
• The use of catalytic models as tools for elucidating the clinical and epidemiological features of trachoma.

  1966cited by this paper
• Experimental inclusion conjunctivitis in man. II. Partial resistance to reinfection.

  1966cited by this paper
• Inoculation of human volunteer with egg-grown inclusion conjunctivitis virus.

  1962cited by this paper

• Does persistent active trachoma mandate antibiotic mass drug administration? A comparison of prevalence of trachomatous inflammation-follicular with that of conjunctival infection and anti-chlamydial antibodies, Western Province, Zambia.

  2025cites this paper
• Trachoma

  2025cites this paper
• Azithromycin during Routine Well-Infant Visits to Prevent Death.

  2024cites this paper
• Unravelling Chlamydia trachomatis diversity in Amhara, Ethiopia: MLVA-ompA sequencing as a molecular typing tool for trachoma

  2024cites this paper
• Modeling the “F” in “SAFE”: The dynamic game of facial cleanliness in trachoma prevention

  2023cites this paper
• Ten Years After Mass Treatment with Two Doses of Azithromycin for Trachoma Elimination in Rombo District – Kilimanjaro: Is Trachoma Still Eliminated? A Case Study of Kahe Mpya Sub-Village

  2023cites this paper
• Trachoma Control: A Glass Half Full?

  2023cites this paper
• Trachoma risk factors in Oromia Region, Ethiopia

  2023cites this paper
• Uses of mathematical modeling to estimate the impact of mass drug administration of antibiotics on antimicrobial resistance within and between communities

  2022cites this paper
• NTD Modelling Consortium discussion group on trachoma

  2021cites this paper
• Targeted antibiotics for trachoma: a cluster-randomized trial.

  2021cites this paper
• DO POOR ENVIRONMENTAL CONDITIONS DRIVE TRACHOMA TRANSMISSION IN BURUNDI? A MATHEMATICAL MODELLING STUDY

  2021cites this paper
• Dynamics of Trachoma Epidemic in Human Contact Network with Seasonally Varying Infectious Medium

  2021cites this paper
• New intervention model to eliminate the spread of trachoma in hyper-endemic community: Based on a mathematical model

  2021cites this paper
• Implications of the COVID-19 pandemic in eliminating trachoma as a public health problem

  2021cites this paper
• Stopping azithromycin mass drug administration for trachoma: A systematic review

  2021cites this paper
• Frequency of mass azithromycin distribution for ocular chlamydia in a trachoma endemic region of Ethiopia: a cluster randomized trial.

  2020cites this paper
• Trachoma: Time to Talk Eradication.

  2020cites this paper
• Predicted Impact of COVID-19 on Neglected Tropical Disease Programs and the Opportunity for Innovation

  2020cites this paper
• Canard Phenomenon in an SIRS Epidemic Model with Nonlinear Incidence Rate

  2020cites this paper
• Implications of the COVID-19 pandemic on eliminating trachoma as a public health problem

  2020cites this paper
• Insights from mathematical modelling and quantitative analysis on the proposed 2030 goals for trachoma

  2019cites this paper
• Exploring the spatial heterogeneity of trachomatous trichiasis

  2019cites this paper
• Stromal Fibroblasts Drive Host Inflammatory Responses That Are Dependent on Chlamydia trachomatis Strain Type and Likely Influence Disease Outcomes

  2019cites this paper
• Antimicrobial resistance following mass azithromycin distribution for trachoma: a systematic review.

  2019cites this paper
• Models of Trachoma Transmission and Their Policy Implications: From Control to Elimination

  2019influential citation
• Progress to Eliminate Trachoma as a Public Health Problem in Amhara National Regional State, Ethiopia: Results of 152 Population-Based Surveys

  2019cites this paper
• Identifying a sufficient core group for trachoma transmission

  2018cites this paper
• Mass azithromycin distribution for hyperendemic trachoma following a cluster-randomized trial: A continuation study of randomly reassigned subclusters (TANA II)

  2018cites this paper
• Models of Trachoma Transmission and Their Policy Implications: From Control to Elimination

  2018influential citation
• Childhood Mortality After Mass Distribution of Azithromycin: A Secondary Analysis of the PRET Cluster-randomized Trial in Niger

  2018cites this paper
• A Cluster-Randomized Trial to Assess the Efficacy of Targeting Trachoma Treatment to Children

  2018influential citation
• Population-based coverage survey results following the mass drug administration of azithromycin for the treatment of trachoma in Amhara, Ethiopia

  2018cites this paper
• The utility of serology for elimination surveillance of trachoma

  2018cites this paper
• Mass drug administration: the importance of synchrony.

  2017cites this paper
• Probabilistic forecasts of trachoma transmission at the district level: A statistical model comparison

  2017cites this paper
• Comparison of Mass Azithromycin Coverage Targets of Children in Niger: A Cluster-Randomized Trachoma Trial.

  2017cites this paper
• The impact of a single round of community mass treatment with azithromycin on disease severity and ocular Chlamydia trachomatis load in treatment-naïve trachoma-endemic island communities in West Africa

  2017cites this paper
• Products of Compartmental Models in Epidemiology

  2017cites this paper
• Hamiltonian Analysis of Subcritical Stochastic Epidemic Dynamics

  2017cites this paper
• Improving our forecasts for trachoma elimination: What else do we need to know?

  2017cites this paper
• Coinfection Dynamics of Two Diseases in a Single Host Population.

  2016cites this paper
• A Cluster-Randomized Trial to Assess the Efficacy of Targeting Trachoma Treatment to Children

  2016cites this paper
• Mathematical Modelling of Trachoma Transmission, Control and Elimination.

  2016cites this paper
• Prospects for trachoma elimination through mass treatment targeted at children

  2016cites this paper
• Enhanced antibiotic distribution strategies and the potential impact of facial cleanliness and environmental improvements for the sustained control of trachoma: a modelling study

  2016cites this paper
• Erratum to: Short-term forecasting of the prevalence of clinical trachoma: utility of including delayed recovery and tests for infection

  2016cites this paper
• Short-term forecasting of the prevalence of clinical trachoma: utility of including delayed recovery and tests for infection

  2015cites this paper
• Correction: Short-term Forecasting of the Prevalence of Trachoma: Expert Opinion, Statistical Regression, versus Transmission Models

  2015cites this paper
• Mass Drug Administration for Trachoma: How Long Is Not Long Enough?

  2015cites this paper
• Estimating the Future Impact of a Multi-Pronged Intervention Strategy on Ocular Disease Sequelae Caused by Trachoma: A Modeling Study

  2015cites this paper
• Possible changes in the transmissibility of trachoma following MDA and transmission reduction: implications for the GET2020 goals

  2015cites this paper
• The distribution of the prevalence of ocular chlamydial infection in communities where trachoma is disappearing

  2015cites this paper
• Short-term Forecasting of the Prevalence of Trachoma: Expert Opinion, Statistical Regression, versus Transmission Models

  2015cites this paper
• The efficacy of oral azithromycin in clearing ocular chlamydia: Mathematical modeling from a community-randomized trachoma trial

  2014cites this paper
• Trachoma.

  2014cites this paper
• Canard phenomenon for an SIS epidemic model with nonlinear incidence

  2014cites this paper
• Active trachoma two years after three rounds of azithromycin mass treatment in Cheha district Gurage zone, Southern Ethiopia

  2013cites this paper
• The Easiest Children to Reach Are Most Likely to Be Infected with Ocular Chlamydia trachomatis in Trachoma Endemic Areas of Niger

  2013cites this paper
• Trachoma and Inclusion Conjunctivitis

  2013cites this paper
• Assessment of Transmission in Trachoma Programs over Time Suggests No Short-Term Loss of Immunity

  2013cites this paper
• Two-Day Dosing versus One-Day Dosing of Azithromycin in Children with Severe Trachoma in Tanzania

  2012cites this paper
• Trachoma and antibiotic use: the ’A‘ in SAFE

  2012cites this paper
• How to Make Epidemiological Training Infectious

  2012cites this paper
• Écologie, évolution et contrôle des maladies tropicales négligées

  2012cites this paper
• The “segment knockout” survey method for large trachoma-endemic districts

  2012cites this paper
• 11 Trachoma and Conjunctivitis

  2012cites this paper
• How reliable are tests for trachoma?--a latent class approach.

  2011cites this paper
• The epidemiological dynamics of infectious trachoma may facilitate elimination.

  2011cites this paper
• The Potential Contribution of Mass Treatment to the Control of Plasmodium falciparum Malaria

  2011cites this paper
• Trachoma and Conjunctivitis

  2011cites this paper
• Number of Years of Annual Mass Treatment With Azithromycin Needed to Control Trachoma in Hyper-endemic Communities in Tanzania

  2011cites this paper
• Conduite à tenir devant une conjonctivite infectieuse

  2011cites this paper
• Surgery to correct trichiasis – the immediate precursor to blindness Antibiotics to treat active disease – azithromycin or 1 % tetracycline eye ointment Azithromycin

  2010cites this paper
• Neglected Tropical Diseases: Infection, Modeling, and Control

  2010cites this paper
• Epidemiology and control of trachoma: systematic review

  2010influential citation
• The decline of pneumococcal resistance after cessation of mass antibiotic distributions for trachoma.

  2010cites this paper
• Modelling trachoma for control programmes.

  2010cites this paper
• Antibiotic Selection Pressure and Macrolide Resistance in Nasopharyngeal Streptococcus pneumoniae: A Cluster-Randomized Clinical Trial

  2010cites this paper
• Modelling Trachoma for Control

  2010cites this paper
• Transmission dynamics and control of trachoma

  2010cites this paper
• Travel and Implications for the Elimination of Trachoma in Ethiopia

  2010cites this paper
• Chlamydia trachomatis Native Major Outer Membrane Protein Induces Partial Protection in Nonhuman Primates: Implication for a Trachoma Transmission-Blocking Vaccine1

  2009cites this paper
• Estimating Household and Community Transmission of Ocular Chlamydia trachomatis

  2009cites this paper
• Reduction and Return of Infectious Trachoma in Severely Affected Communities in Ethiopia

  2009cites this paper
• Trachoma Transmission-Blocking Vaccine in Nonhuman Primates : Implication for a ProtectionMembrane Protein Induces Partial Native Major Outer Chlamydia trachomatis

  2009cites this paper
• Trachoma and ocular Chlamydia trachomatis rates in children in trachoma-endemic communities enrolled for at least three years in the Tanzania National Trachoma Control Programme.

  2009cites this paper
• Complete local elimination of infectious trachoma from severely affected communities after six biannual mass azithromycin distributions.

  2009cites this paper
• Importance of Coverage and Endemicity on the Return of Infectious Trachoma after a Single Mass Antibiotic Distribution

  2009cites this paper
• The Development of an Age-Structured Model for Trachoma Transmission Dynamics, Pathogenesis and Control

  2009cites this paper
• Effect of mass distribution of azithromycin for trachoma control on overall mortality in Ethiopian children: a randomized trial.

  2009cites this paper
• Randomized Trial of High Dose Azithromycin Compared to Standard Dosing for Children with Severe Trachoma in Tanzania

  2009cites this paper
• Strategies to Control Trachoma

  2009cites this paper
• Assessment of herd protection against trachoma due to repeated mass antibiotic distributions: a cluster-randomised trial.

  2009cites this paper
• Complete elimination is a difficult goal for trachoma programs in severely affected communities.

  2008cites this paper
• Development of a Chlamydia trachomatis bacterial ghost vaccine to fight human blindness

  2008cites this paper
• Risk factors for active trachoma and Chlamydia trachomatis infection in rural Ethiopia after mass treatment with azithromycin

  2008cites this paper
• Comparison of annual and biannual mass antibiotic administration for elimination of infectious trachoma.

  2008cites this paper
• Infectious syphilis in high-income settings in the 21st century.

  2008cites this paper
• The Natural History of Trachoma Infection and Disease in a Gambian Cohort with Frequent Follow-Up

  2008cites this paper