Enduring consequences of neonatal treatment with antisense oligodeoxynucleotides to estrogen receptor messenger ribonucleic acid on sexual differentiation of rat brain.

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Endocrinology

• Publication date

  1993-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1210/ENDO.133.2.8344188PMID 8344188
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Organotypic culture of the developing cerebral cortex and hypothalamus: relevance to sexual differentiation.

  1991cited by this paper
• Antisense oligonucleotides for therapeutic intervention.

  1991cited by this paper
• Tamoxifen fails to block estradiol accumulation, yet is weakly accumulated by the juvenile zebra finch anterior hypothalamus: an autoradiographic study.

  1991cited by this paper
• Antisense oligonucleotides: a new therapeutic principle

  1990cited by this paper
• Termination of the hormone-sensitive period for differentiation of the sexually dimorphic nucleus of the preoptic area in male and female rats.

  1990cited by this paper
• Sexual dimorphism in the parastrial nucleus of the rat preoptic area.

  1990cited by this paper
• Sexual orientation, proceptivity, and receptivity in the male rat as a function of neonatal hormonal manipulation.

  1988cited by this paper
• Improved tools for biological sequence comparison.

  1988cited by this paper
• Cytoarchitectonic analysis of the SDN‐POA of the intact and gonadectomized rat

  1988cited by this paper
• Pre- and postnatal influence of an estrogen antagonist and an androgen antagonist on differentiation of the sexually dimorphic nucleus of the preoptic area in male and female rats.

  1986cited by this paper
• Identification of medial preoptic neurons that concentrate estradiol and project to the midbrain in the rat

  1986cited by this paper
• The 13th J. A. F. Stevenson memorial lecture. Sexual differentiation of the brain: possible mechanisms and implications.

  1985cited by this paper
• Preoptic implants of estradiol increase wheel running but not the open field activity of female rats.

  1985cited by this paper
• The sexually dimorphic region of the preoptic area in rats contains denser opiate receptor binding sites in females.

  1984cited by this paper
• Differentiation of the sexually dimorphic nucleus in the preoptic area of the rat brain is inhibited by postnatal treatment with an estrogen antagonist.

  1984cited by this paper
• Coexistence of alpha-fetoprotein, albumin and transferrin immunoreactivity in neurones of the developing mouse brain.

  1980cited by this paper
• Priming of estrous responsiveness by implants of 17 beta-estradiol in the ventromedial hypothalamic nucleus of female rats.

  1980cited by this paper
• Evidence for the existence of a sexually dimorphic nucleus in the preoptic area of the rat

  1980cited by this paper
• Suppression of sexual receptivity in the female hamster: neuroanatomical projections from preoptic and anterior hypothalamic electrode sites.

  1980cited by this paper
• Coexistence of alpha-fetoprotein, albumin and transferrin immunoreactivity in neurones of the developing mouse brain.

  1980cited by this paper
• Aromatization: important for sexual differentiation of the neonatal rat brain.

  1977cited by this paper
• Sex differences in open-field behavior in the rat: the inductive and activational role of gonadal hormones.

  1975cited by this paper
• Critical exposure time for androgenization by intracranial crystals of testosterone propionate in neonatal female rats.

  1974cited by this paper
• Daily and hourly estrous running in intact, spayed and estrone implanted rats.

  1973cited by this paper
• Sexual Receptivity: Facilitation by Medial Preoptic Lesions in Female Rats

  1972cited by this paper
• Neonatal androgen effects on sexual and non-sexual behavior of adult rats tested under various hormone regimes.

  1971cited by this paper
• Critical exposure time for androgenization of the developing hypothalamus in the female rat.

  1968cited by this paper

• Microglia phagocytosis mediates the volume and function of the rat sexually dimorphic nucleus of the preoptic area

  2023cites this paper
• Distribution of androgen receptor mRNA in the prepubertal male and female mouse brain

  2021cites this paper
• Does GPER1 Play a Role in Sexual Dimorphism?

  2020cites this paper
• Key role of estrogen receptor β in the organization of brain and behavior of the Japanese quail.

  2020cites this paper
• How technical progress reshaped behavioral neuroendocrinology during the last 50 years… and some methodological remarks.

  2020cites this paper
• Sex Differences in Brain Injury and Repair in Newborn Infants: Clinical Evidence and Biological Mechanisms

  2019cites this paper
• Age‐specific associations between oestradiol, cortico‐amygdalar structural covariance, and verbal and spatial skills

  2019cites this paper
• Neuroscience and Sex/Gender: Looking Back and Forward

  2019cites this paper
• Androgen and estrogen actions on male physical activity: a story beyond muscle.

  2018cites this paper
• Cellular and Molecular Mechanisms of the Effects of Sex Hormones on the Nervous System

  2017cites this paper
• 5.01 – Sexual Differentiation of the Brain: A Fresh Look at Mode, Mechanisms, and Meaning

  2017cites this paper
• Prepubertal ovariectomy modulates paced mating behavior but not sexual preference or conditioned place preference for mating in female rats.

  2017cites this paper
• Muscimol microinjected in the arcuate nucleus affects metabolism, body temperature & ventilation.

  2016cites this paper
• Estrogen in prefrontal cortex blocks stress-induced cognitive impairments in female rats.

  2016cites this paper
• Kisspeptin in the Hypothalamus of 2 Rat Models of Polycystic Ovary Syndrome

  2016cites this paper
• Sex and the Developing Brain

  2016cites this paper
• Brain feminization requires active repression of masculinization via DNA methylation

  2015cites this paper
• Brain feminization requires active repression of masculinization via DNA methylation

  2015cites this paper
• Sex differences in the brain: a whole body perspective

  2015cites this paper
• Etiologies underlying sex differences in Autism Spectrum Disorders.

  2014cites this paper
• Location, location, location: Genetic regulation of neural sex differences

  2012cites this paper
• Sexually Selected Traits: A Fundamental Framework for Studies on Behavioral

  2012cites this paper
• Anatomically‐Specific Actions of Oestrogen Receptor in the Developing Female Rat Brain: Effects of Oestradiol and Selective Oestrogen Receptor Modulators on Progestin Receptor Expression

  2012cites this paper
• Sexual responses of the male rat medial preoptic area and medial amygdala to estrogen I: site specific suppression of estrogen receptor alpha.

  2012cites this paper
• Sex and steroid hormones in early brain injury

  2012cites this paper
• Sexually selected traits: a fundamental framework for studies on behavioral epigenetics.

  2012cites this paper
• Sexual Differentiation of the Mammalian Brain

  2011cites this paper
• Expression of Oestrogen Receptor α in the Brain of Brandt’s Voles (Lasiopodomys brandtii ): Sex Differences and Variations During Ovarian Cycles

  2011cites this paper
• Hormonally mediated epigenetic changes to steroid receptors in the developing brain: implications for sexual differentiation.

  2011cites this paper
• Control of cell number in the bed nucleus of the stria terminalis of mice: role of testosterone metabolites and estrogen receptor subtypes.

  2010cites this paper
• Sex differences in epigenetic regulation of the estrogen receptor-alpha promoter within the developing preoptic area.

  2010cites this paper
• Cellular mechanisms of estradiol-mediated sexual differentiation of the brain.

  2010cites this paper
• Ventromedial and medial preoptic hypothalamic ibotenic acid lesions potentiate systemic morphine analgesia in female, but not male rats.

  2010cites this paper
• Of mice and rats: key species variations in the sexual differentiation of brain and behavior.

  2010cites this paper
• Estrogen configures sexual dimorphism in the preoptic area of C57BL/6J and ddN strains of mice

  2010cites this paper
• Estrogen receptor {alpha} gene promoter 0/B usage in the rat sexually dimorphic nucleus of the preoptic area.

  2010cites this paper
• Nuclear Receptor Coactivators: Essential Players for Steroid Hormone Action in the Brain and in Behaviour

  2009cites this paper
• Antisense oligodeoxynucleotide complementary to oxytocin mRNA blocks lactation in rats.

  2009cites this paper
• Sexual Differentiation of the Brain: Mode, Mechanisms, and Meaning

  2009cites this paper
• Sexual differentiation of rat reproductive versus opioid antinociceptive systems.

  2009cites this paper
• Molecular genomics of progestin actions

  2009cites this paper
• Who's in charge? Nuclear receptor coactivator and corepressor function in brain and behavior.

  2009influential citation
• Estradiol induces hypothalamic dendritic spines by enhancing glutamate release: a mechanism for organizational sex differences.

  2008cites this paper
• Estradiol and the developing brain.

  2008cites this paper
• Dopaminergic Activation of Estrogen Receptors Induces Fos Expression within Restricted Regions of the Neonatal Female Rat Brain

  2008cites this paper
• Identification and interpretation of developmental neurotoxicity effects: a report from the ILSI Research Foundation/Risk Science Institute expert working group on neurodevelopmental endpoints.

  2008cites this paper
• Steroid‐induced sexual differentiation of the developing brain: multiple pathways, one goal

  2008cites this paper
• The androgen receptor is selectively involved in organization of sexually dimorphic social behaviors in mice.

  2008cites this paper
• Androgen receptor is essential for sexual differentiation of responses to olfactory cues in mice

  2007cites this paper
• Differential Effects of Estrogen Receptor alpha Suppression by Antisense Oligodeoxynucleotides in the Medial Preoptic Area and the Medial Amygdala on Male Rat Mating Behavior

  2007cites this paper
• Effects of organisational oestradiol on adult immunoreactive oestrogen receptors (alpha and beta) in the male mouse brain.

  2007cites this paper
• Developmental exposure to low-dose estrogenic endocrine disruptors alters sex differences in exploration and emotional responses in mice.

  2007cites this paper
• Estradiol-Induced Conditioned Place Preference may Require Actions at Estrogen Receptors in the Nucleus Accumbens

  2007cites this paper
• Transient transcription of the somatostatin gene at the time of estrogen-dependent organization of the sexually dimorphic nucleus of the rat preoptic area.

  2007cites this paper
• Effects of Organisational Oestradiol on Adult Immunoreactive Oestrogen Receptors (α and β) in the Male Mouse Brain

  2007cites this paper
• Sex Differences in Neurotransmitters and Behavior: Development

  2007cites this paper
• CHAPTER 34 – Hormonal, Neural, and Genomic Mechanisms for Female Reproductive Behaviors, Motivation, and Arousal

  2006cites this paper
• Sex, hormones and affective arousal circuitry dysfunction in schizophrenia.

  2006cites this paper
• Function of estrogen receptor isoforms alpha and beta in endometrial carcinoma cells.

  2006cites this paper
• Mechanisms underlying estrogen-induced sexual differentiation in the hypothalamus.

  2006cites this paper
• The effect of aromatase inhibition on the sexual differentiation of the sheep brain

  2006cites this paper
• Permanent effects of postnatal administration of beta-adrenergic ligands on the volume of sexually dimorphic nucleus of the preoptic area (SDN-POA) in rats.

  2006cites this paper
• Evidence of altered brain sexual differentiation in mice exposed perinatally to low, environmentally relevant levels of bisphenol A.

  2006cites this paper
• Steroid Sensitive Neurons and Male Rat Mating Behavior

  2006cites this paper
• Function of estrogen receptor isoforms α and β in endometrial carcinoma cells

  2006cites this paper
• Modulation of Hormonal Signaling in the Brain by Steroid Receptor Coactivators

  2005cites this paper
• Long term dietary methoxychlor exposure in rats increases sodium solution consumption but has few effects on other sexually dimorphic behaviors.

  2005cites this paper
• Developmental Exposure to Environmental Estrogens Alters Adult Behavior in Female Rodents

  2005cites this paper
• Neuroendocrine Consequences of Prenatal Androgen Exposure in the Female Rat: Absence of Luteinizing Hormone Surges, Suppression of Progesterone Receptor Gene Expression, and Acceleration of the Gonadotropin-Releasing Hormone Pulse Generator1

  2005cites this paper
• The role of the androgen receptor in CNS masculinization.

  2005cites this paper
• Perinatal Androgenization Prevents Age-Related Neuron Loss in the Sexually Dimorphic Nucleus of the Preoptic Area in Female Rats

  2004cites this paper
• Brain estradiol content in newborn rats: sex differences, regional heterogeneity, and possible de novo synthesis by the female telencephalon.

  2004cites this paper
• Genetic Influences on Aggressive Behaviors and Arousability in Animals

  2004cites this paper
• Differential colocalization of Islet-1 and estrogen receptor alpha in the murine preoptic area and hypothalamus during development.

  2004cites this paper
• In utero effects of chemicals on reproductive tissues in females.

  2004cites this paper
• Steroid receptor control of reproductive behavior.

  2004cites this paper
• Membrane-Associated Estrogen Receptors and Breast Cancer

  2003cites this paper
• Immediate and residual effects of tamoxifen and ethynylestradiol in the female rat hypothalamus.

  2003cites this paper
• Activational and organizational effects of estradiol on male behavioral neuroendocrine function.

  2003cites this paper
• Sexually dimorphic and estrogen-dependent expression of estrogen receptor beta in the ventromedial hypothalamus during rat postnatal development.

  2003cites this paper
• Estrogen Synthesis in Fetal Sheep Brain: Effect of Maternal Treatment with an Aromatase Inhibitor1

  2003cites this paper
• Minireview. Nuclear Receptor Coactivator Function in Reproductive Physiology and Behavior1

  2003cites this paper
• Monoaminergic and cholinergic stimulation of masculine sexual behavior in neonatally demasculinized male rats.

  2002cites this paper
• Masculinization and Defeminization in Altricial and Precocial Mammals: Comparative Aspects of Steroid Hormone Action

  2002cites this paper
• Neurobehavioral actions of coumestrol and related isoflavonoids in rodents.

  2002cites this paper
• Getting excited about GABA and sex differences in the brain.

  2002cites this paper
• Genetic Mechanisms in Neural and Hormonal Controls over Female Reproductive Behaviors

  2002cites this paper
• Anatomy, Development, and Function of Sexually Dimorphic Neural Circuits in the Mammalian Brain

  2002cites this paper
• Estrogen receptor beta is involved in the anorectic action of estrogen.

  2002cites this paper
• GABA Mediates Steroid‐Induced Astrocyte Differentiation in the Neonatal Rat Hypothalamus

  2002cites this paper
• Neonatal sex steroids affect ventilatory responses to aspartic acid and NMDA receptor subunit 1 in rats.

  2002cites this paper
• Oestrogen's masculine side: mediation of mating in male mice.

  2002cites this paper
• Estrogen receptor ß is involved in the anorectic action of estrogen

  2002cites this paper
• Expression of the nuclear receptor coactivator, cAMP response element-binding protein, is sexually dimorphic and modulates sexual differentiation of neonatal rat brain.

  2002cites this paper
• Selected Contribution: Estrogen receptor-α antisense decreases brain estrogen receptor levels and affects ventilation in male and female rats

  2001cites this paper
• Influence of sex and estrus cycle on the sexual dimorphisms of the hypothalamic ventromedial nucleus: Stereological evaluation and golgi study

  2001cites this paper
• Development of Sex Differences in the Nervous System

  2001cites this paper
• The anti-amnesic effects of sigma1 (sigma1) receptor agonists confirmed by in vivo antisense strategy in the mouse.

  2001cites this paper
• Sex differences in progesterone receptor immunoreactivity in neonatal mouse brain depend on estrogen receptor alpha expression.

  2001cites this paper
• Cloning and in Vitro Characterization ofα 1(I)-Collagen 11β-Hydroxysteroid Dehydrogenase Type 2 Transgenes as Models for Osteoblast-Selective Inactivation of Natural Glucocorticoids.

  2001cites this paper