The FHA domain in DNA repair and checkpoint signaling.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Cold Spring Harbor Symposia on Quantitative Biology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1101/SQB.2000.65.423PMID 12760058
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Sensing and responding to DNA damage.

  2000cited by this paper
• The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms.

  2000cited by this paper
• Protein-protein interactions define specificity in signal transduction.

  2000cited by this paper
• FHA domain boundaries of the Dun1p and Rad53p cell cycle checkpoint kinases

  2000cited by this paper
• hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

  2000cited by this paper
• Forkhead-like transcription factors recruit Ndd1 to the chromatin of G2/M-specific promoters

  2000cited by this paper
• Two yeast forkhead genes regulate the cell cycle and pseudohyphal growth

  2000cited by this paper
• Chfr defines a mitotic stress checkpoint that delays entry into metaphase

  2000cited by this paper
• Genetic diversity and disease control in rice

  2000cited by this paper
• The FHA domain is a modular phosphopeptide recognition motif.

  1999cited by this paper
• Signal transduction: Grabbing phosphoproteins

  1999cited by this paper
• Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand binding.

  1999cited by this paper
• Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks.

  1999cited by this paper
• Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome.

  1999cited by this paper
• Kinase interaction domain of kinase-associated protein phosphatase, a phosphoprotein-binding domain.

  1999cited by this paper
• Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition.

  1999cited by this paper
• Structure and function of a new phosphopeptide-binding domain containing the FHA2 of Rad53.

  1999cited by this paper
• Function of WW domains as phosphoserine- or phosphothreonine-binding modules.

  1999cited by this paper
• Positional cloning of the gene for Nijmegen breakage syndrome

  1998cited by this paper
• Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome.

  1998cited by this paper
• Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization.

  1998cited by this paper
• The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response.

  1998cited by this paper
• Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint.

  1998cited by this paper
• MEC1-dependent phosphorylation of Rad9p in response to DNA damage.

  1998cited by this paper
• Structure of a Numb PTB domain–peptide complex suggests a basis for diverse binding specificity

  1998cited by this paper
• The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1‐dependent hyperphosphorylation and interacts with Rad53 after DNA damage

  1998cited by this paper
• Control of cell cycle arrest by the Mec1sc/Rad3sp DNA structure checkpoint pathway.

  1997cited by this paper
• High-affinity binding of the Drosophila Numb phosphotyrosine-binding domain to peptides containing a Gly-Pro-(p)Tyr motif.

  1997cited by this paper
• Modular peptide recognition domains in eukaryotic signaling.

  1997cited by this paper
• RAD9 and DNA polymerase epsilon form parallel sensory branches for transducing the DNA damage checkpoint signal in Saccharomyces cerevisiae.

  1996cited by this paper
• Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways.

  1996cited by this paper
• A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage.

  1995cited by this paper
• Structure and ligand recognition of the phosphotyrosine binding domain of Shc

  1995cited by this paper
• A single ataxia telangiectasia gene with a product similar to PI-3 kinase.

  1995cited by this paper
• The FHA domain: a putative nuclear signalling domain found in protein kinases and transcription factors.

  1995cited by this paper
• Measurement of the binding of tyrosyl phosphopeptides to SH2 domains: a reappraisal.

  1995cited by this paper
• Interaction of a protein phosphatase with an Arabidopsis serine-threonine receptor kinase.

  1994cited by this paper
• An essential gene, ESR1, is required for mitotic cell growth, DNA repair and meiotic recombination in Saccharomyces cerevisiae.

  1994cited by this paper
• Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair.

  1994cited by this paper
• The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast.

  1994cited by this paper
• Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms.

  1993cited by this paper
• Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck

  1993cited by this paper
• DUN1 encodes a protein kinase that controls the DNA damage response in yeast.

  1993cited by this paper
• The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae.

  1988cited by this paper

• Functional analysis of a conserved site mutation in the DNA end processing enzyme PNKP leading to ataxia with oculomotor apraxia type 4 in humans

  2023cites this paper
• FHA domain of AGGF1 is essential for its nucleocytoplasmic transport and angiogenesis

  2021cites this paper
• The Fkh1 Forkhead associated domain promotes ORC binding to a subset of DNA replication origins in budding yeast

  2021cites this paper
• Versatility in phospho dependent molecular recognition of the XRCC 1 and XRCC 4 DNA damage scaffolds by aprataxin family

  2019cites this paper
• Structural insights into the recognition of phosphorylated Hop1 by Mek1.

  2018cites this paper
• Versatility in phospho-dependent molecular recognition of the XRCC1 and XRCC4 DNA-damage scaffolds by aprataxin-family FHA domains

  2015cites this paper
• The PIN domain of EXO1 recognizes poly(ADP-ribose) in DNA damage response

  2015cites this paper
• Molecular underpinnings of Aprataxin RNA/DNA deadenylase function and dysfunction in neurological disease.

  2015influential citation
• Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children

  2015cites this paper
• GSK3 and Polo-like kinase regulate ADAM13 function during cranial neural crest cell migration

  2014cites this paper
• Virus-host interactions in persistently FMDV-infected cells derived from bovine pharynx.

  2014cites this paper
• The Interaction of CtIP and Nbs1 Connects CDK and ATM to Regulate HR–Mediated Double-Strand Break Repair

  2013cites this paper
• Targeting Protein for Xenopus Kinesin-like Protein 2 (TPX2) Regulates γ-Histone 2AX (γ-H2AX) Levels upon Ionizing Radiation*

  2012cites this paper
• Division and cell envelope regulation by Ser/Thr phosphorylation: Mycobacterium shows the way

  2010cites this paper
• Oligonucleotide/oligosaccharide-binding fold proteins: a growing family of genome guardians

  2010cites this paper
• Specific recognition of a multiply phosphorylated motif in the DNA repair scaffold XRCC1 by the FHA domain of human PNK

  2009cites this paper
• Investigations on phosphospecific interactions in the DNA damage response

  2009cites this paper
• Nucleic Acids Research

  2009cites this paper
• Maintenance of the DNA-damage checkpoint requires DNA-damage-induced mediator protein oligomerization.

  2009cites this paper
• Yeast Chfr homologs retard cell cycle at G1 and G2/M via Ubc4 and Ubc13/Mms2-dependent ubiquitination

  2008cites this paper
• Structure of a second BRCT domain identified in the nijmegen breakage syndrome protein Nbs1 and its function in an MDC1-dependent localization of Nbs1 to DNA damage sites.

  2008cites this paper
• Checkpoint Regulation of S-Phase Transcription: A Dissertation

  2008cites this paper
• Mechanisms of Activation and Inactivation of Rad53 Checkpoint Kinase

  2008cites this paper
• Kinase-interacting FHA domain of kinase associated protein phosphatase : phosphopeptide interactions and NMR-detected dynamics

  2007cites this paper
• SNIP1: Myc's new helper in transcriptional activation.

  2006cites this paper
• Ccr4 contributes to tolerance of replication stress through control of CRT1 mRNA poly(A) tail length

  2006cites this paper
• gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes.

  2006cites this paper
• Análises de transcritos de Paracoccidioides brasiliensis durante a transição dimórfica de micélio para levedura

  2006cites this paper
• EDD Mediates DNA Damage-induced Activation of CHK2*

  2006cites this paper
• Functional studies of serine/threonine protein kinase signalling in Mycobacterium tuberculosis

  2006influential citation
• Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1

  2005cites this paper
• Chromatin and the DNA damage response.

  2005cites this paper
• Synthetic modular systems – reverse engineering of signal transduction

  2005cites this paper
• Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein and its complex with tungstate.

  2002cites this paper
• The FHA domain

  2002cites this paper
• Interfaces Between the Detection, Signaling, and Repair of DNA Damage

  2002cites this paper
• Bmc Microbiology

  year unknowncites this paper
• Inherited Coding Variants at the Cdkn2a Locus Influence Susceptibility to Acute Lymphoblastic Leukaemia in Children Recommended Citation

  year unknowncites this paper