Age-dependent impairment of angiogenesis.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Circulation

• Publication date

  1999-01-12

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1161/01.CIR.99.1.111PMID 9884387
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2000cited by this paper
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  1998cited by this paper
• Mouse model of angiogenesis.

  1998cited by this paper
• Factors controlling T-cell migration across rat cerebral endothelium in vitro.

  1997cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1995cited by this paper
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  1995cited by this paper
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  1994influential reference
• Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only.

  1994cited by this paper
• Age‐Related Changes in Release of Endothelium‐Derived Relaxing Factor From the Carotid Artery

  1994cited by this paper
• Altered angiogenesis underlying age-dependent changes in tumor growth.

  1994cited by this paper
• Angiogenic-induced enhancement of collateral blood flow to ischemic myocardium by vascular endothelial growth factor in dogs.

  1994cited by this paper
• Enhanced angiogenesis and growth of collaterals by in vivo administration of recombinant basic fibroblast growth factor in a rabbit model of acute lower limb ischemia: dose-response effect of basic fibroblast growth factor.

  1992cited by this paper
• Remodeling of coronary vessels during aging in purebred beagles.

  1991cited by this paper
• Effect of host age on tumor-associated angiogenesis in mice.

  1990cited by this paper
• Lymphocyte-induced angiogenesis factor is produced by L3T4+ murine T lymphocytes, and its production declines with age

  1988cited by this paper
• Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

  1987cited by this paper
• Mechanisms of angiogenesis.

  1987cited by this paper
• CHAPTER 14 – Neoplastic Diseases

  1974cited by this paper
• Neoplastic diseases.

  1952cited by this paper

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