General Pharmacology of Anesthetic and Analgesic Drugs

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Unknown venue

• Publication date

  2017-04-28

• Fields of study

  Medicine

• Identifiers
  DOI 10.1002/9781119421375.CH7
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Opioid antagonists for pain

  2013cited by this paper
• The Author Response: Suspected Anaphylactic Reaction Associated with Microemulsion Propofol during Anesthesia Induction

  2013cited by this paper
• Sevoflurane Remifentanil Interaction: Comparison of Different Response Surface Models

  2012cited by this paper
• Effects of clenbuterol administration on serum biochemical, histologic, and echocardiographic measurements of muscle injury in exercising horses.

  2012cited by this paper
• Comparative canine pharmacokinetics-pharmacodynamics of fospropofol disodium injection, propofol emulsion, and cyclodextrin-enabled propofol solution following bolus parenteral administration.

  2012cited by this paper
• Recirculatory pharmacokinetic modeling: what goes around, comes around.

  2012cited by this paper
• Dose determination of fondaparinux in healthy cats.

  2012cited by this paper
• Evaluation of polymorphisms in the sulfonamide detoxification genes CYB5A and CYB5R3 in dogs with sulfonamide hypersensitivity.

  2012cited by this paper
• Breed distribution of the nt230(del4) MDR1 mutation in dogs.

  2011cited by this paper
• Glucocorticosteroids: current and future directions

  2011cited by this paper
• Acute selenium toxicosis in polo ponies

  2011cited by this paper
• Effectiveness, safety, and pharmacokinetic and pharmacodynamic characteristics of microemulsion propofol in patients undergoing elective surgery under total intravenous anaesthesia.

  2010cited by this paper
• Adrenergic Support in Septic Shock: A Critical Review

  2010cited by this paper
• Glutamate Receptor Ion Channels: Structure, Regulation, and Function

  2010cited by this paper
• Responses in fish exposed to medetomidine, a new antifouling agent.

  2010cited by this paper
• Canine CYP2B11 metabolizes and is inhibited by anesthetic agents often co-administered in dogs.

  2010cited by this paper
• Metabolic stability and determination of cytochrome P450 isoenzymes' contribution to the metabolism of medetomidine in dog liver microsomes.

  2009cited by this paper
• Evaluation of anesthesia recovery quality after low-dose racemic or S-ketamine infusions during anesthesia with isoflurane in horses.

  2009cited by this paper
• Plasma pharmacokinetics of alfaxalone in both premedicated and unpremedicated Greyhound dogs after single, intravenous administration of Alfaxan at a clinical dose.

  2009cited by this paper
• Effects of medetomidine on hepatic EROD activity in three species of fish.

  2008cited by this paper
• Implications of hepatic cytochrome P450-related biotransformation processes in veterinary sciences.

  2008cited by this paper
• Stereoselective pharmacokinetics of ketamine and norketamine after racemic ketamine or S-ketamine administration in Shetland ponies sedated with xylazine.

  2008cited by this paper
• Multistate outbreak of Pseudomonas fluorescens bloodstream infection after exposure to contaminated heparinized saline flush prepared by a compounding pharmacy.

  2008cited by this paper
• Buprenorphine: New Tricks With an Old Molecule for Pain Management

  2008cited by this paper
• Quality, safety and efficacy in the 'off-label' use of medicines.

  2007cited by this paper
• Total intravenous techniques for anaesthesia

  2007cited by this paper
• Rat Cytochrome P450 2C11 in Liver Microsomes Involved in Oxidation of Anesthetic Agent Propofol and Deactivated by Prior Treatment with Propofol

  2006cited by this paper
• Opioid–Volatile Anesthetic Synergy: A Response Surface Model with Remifentanil and Sevoflurane as Prototypes

  2006cited by this paper
• Effects of intravenous administration of lidocaine on the thermal threshold in cats.

  2006cited by this paper
• Cytochrome P450 and its role in veterinary drug interactions.

  2006cited by this paper
• The effect of positive end‐expiratory pressure ventilation on propofol concentrations during general anesthesia in humans

  2006cited by this paper
• Propofol metabolism is enhanced after repetitive ketamine administration in rats: the role of cytochrome P-450 2B induction.

  2006cited by this paper
• Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction

  2006cited by this paper
• Induction of phase I, II and III drug metabolism/transport by xenobiotics

  2005cited by this paper
• Assessment of the hemodynamic effects of lidocaine administered IV in isoflurane-anesthetized cats.

  2005cited by this paper
• Effect of propofol on ropivacaine metabolism in human liver microsomes

  2005cited by this paper
• Frequency of the nt230 (del4) MDR1 mutation in Collies and related dog breeds in Germany.

  2005cited by this paper
• Predictive performance of 'Diprifusor' TCI system in patients during upper abdominal surgery under propofol/fentanyl anesthesia.

  2005cited by this paper
• Pharmacokinetic/pharmacodynamic modelling of NSAIDs in a model of reversible inflammation in the cat

  2005cited by this paper
• A general method for calculating the dosage scheme in linear pharmacokinetics

  2004cited by this paper
• Applications cliniques de la pharmacologie des agents anesthésiques intraveineux (hypnotiques et morphiniques)

  2004cited by this paper
• Direct Cardiac Effects of Coronary Site-directed Thiopental and Its Enantiomers: A Comparison to Propofol in Conscious Sheep

  2004cited by this paper
• Adverse drug event reports at the United States Food And Drug Administration Center for Veterinary Medicine.

  2004cited by this paper
• Influence of the prone position on propofol pharmacokinetics

  2004cited by this paper
• Bioavailability and its assessment.

  2004cited by this paper
• Volumes of distribution.

  2004cited by this paper
• Plasma terminal half-life.

  2004cited by this paper
• Strategies to Optimise Propofol-Opioid Anaesthesia

  2004cited by this paper
• Performance of Target-controlled Sufentanil Infusion in Obese Patients

  2003cited by this paper
• The development and future of target controlled infusion.

  2003cited by this paper
• Propofol inhibits lidocaine metabolism in human and rat liver microsomes

  2003cited by this paper
• Response surface modelling of drug interactions.

  2003cited by this paper
• Impact of Drug Transporter Studies on Drug Discovery and Development

  2003cited by this paper
• Overview of the voltage-gated sodium channel family

  2003cited by this paper
• Propofol Reduces Perioperative Remifentanil Requirements in a Synergistic Manner: Response Surface Modeling of Perioperative Remifentanil–Propofol Interactions

  2003cited by this paper
• Drug metabolism and drug interactions: application and clinical value of in vitro models.

  2003cited by this paper
• Basic pharmacokinetic principles for intravenous anaesthesia.

  2003cited by this paper
• Target-controlled drug delivery: progress toward an intravenous "vaporizer" and automated anesthetic administration.

  2003cited by this paper
• Inhaled Anesthetics and Immobility: Mechanisms, Mysteries, and Minimum Alveolar Anesthetic Concentration

  2003cited by this paper
• Using the Time of Maximum Effect Site Concentration to Combine Pharmacokinetics and Pharmacodynamics

  2003cited by this paper
• Context-Sensitive Half-Times

  2002cited by this paper
• Clinical efficacy and pharmacokinetics of carprofen in the treatment of dogs with osteoarthritis

  2002cited by this paper
• Free drug fraction vs free drug concentration: a matter of frequent confusion.

  2002cited by this paper
• Efficient Trial Design for Eliciting a Pharmacokinetic– Pharmacodynamic Model–based Response Surface Describing the Interaction between Two Intravenous Anesthetic Drugs

  2002cited by this paper
• Inhibition of cytochrome P450 2E1 by propofol in human and porcine liver microsomes.

  2002cited by this paper
• Influence of Cardiac Output on Plasma Propofol Concentrations during Constant Infusion in Swine

  2002cited by this paper
• Ivermectin sensitivity in collies is associated with a deletion mutation of the mdr1 gene.

  2001cited by this paper
• Epinephrine, norepinephrine and dopamine infusions decrease propofol concentrations during continuous propofol infusion in an ovine model

  2001cited by this paper
• U-shaped dose-responses in biology, toxicology, and public health.

  2001cited by this paper
• Evaluation and optimisation of a targetcontrolled infusion system for administering propofol to dogs as part of a total intravenous anaesthetic technique during dental surgery

  2001cited by this paper
• Propofol-induced cytochrome P450 inhibition: an in vitro and in vivo study in rats.

  2001cited by this paper
• Pharmacodynamics and pharmacokinetics of ketoprofen enantiomers in sheep.

  2001cited by this paper
• Quantification of pharmacodynamic interactions between dexmedetomidine and midazolam in the rat.

  2000cited by this paper
• Response Surface Model for Anesthetic Drug Interactions

  2000cited by this paper
• Adverse drug reactions: definitions, diagnosis, and management.

  2000cited by this paper
• Isoflurane Alters the Recirculatory Pharmacokinetics of Physiologic Markers

  2000cited by this paper
• Comparison of Plasma Compartment versus Two Methods for Effect Compartment–controlled Target-controlled Infusion for Propofol

  2000cited by this paper
• Evidence for propofol hydroxylation by cytochrome P4502B11 in canine liver microsomes: breed and gender differences

  2000cited by this paper
• Targeting effect compartment or central compartment concentration of propofol: what predicts loss of consciousness?

  1999cited by this paper
• Propofol hydroxylation by dog liver microsomes: assay development and dog breed differences.

  1999cited by this paper
• The physiological and pharmacological roles of cytochrome P450 isoenzymes

  1999cited by this paper
• Evidence for polymorphism in the canine metabolism of the cyclooxygenase 2 inhibitor, celecoxib.

  1999cited by this paper
• A model of the kinetics and dynamics of induction of anaesthesia in sheep: variable estimation for thiopental and comparison with propofol.

  1999cited by this paper
• The development of ‘Diprifusor’: a TCI system for propofol

  1998cited by this paper
• General anesthesia

  1998cited by this paper
• Pharmacokinetics of propofol during conscious sedation using target-controlled infusion in anxious patients undergoing dental treatment.

  1998cited by this paper
• Pharmacokinetic concepts for TCI anaesthesia

  1998cited by this paper
• Evaluation of the predictive performance of a ‘Diprifusor’ TCI system

  1998cited by this paper
• Inclusion Complexation of Propofol with 2-Hydroxypropyl-β- cyclodextrin. Physicochemical, Nuclear Magnetic Resonance Spectroscopic Studies, and Anesthetic Properties in Rat

  1998cited by this paper
• Target controlled infusions

  1998cited by this paper
• Inhibition and Induction of Cytochrome P450 and the Clinical Implications

  1998cited by this paper
• TCI: supplementation and drug interactions

  1998cited by this paper
• Effects of propofol on human hepatic microsomal cytochrome P450 activities.

  1998cited by this paper
• Development of the technology for ‘Diprifusor’ TCI systems

  1998cited by this paper
• Bi-directional chiral inversion of ketoprofen in CD-1 mice.

  1997cited by this paper
• A physiological model of induction of anaesthesia with propofol in sheep. 1. Structure and estimation of variables.

  1997cited by this paper
• The in vitro interaction of dexmedetomidine with human liver microsomal cytochrome P4502D6 (CYP2D6).

  1997cited by this paper
• Effect of alfentanil on the minimum alveolar concentration of isoflurane in cats.

  1997cited by this paper
• GABAA receptor pharmacology.

  1996cited by this paper
• Comparisons of phase I and phase II in vitro hepatic enzyme activities of human, dog, rhesus monkey, and cynomolgus monkey.

  1995cited by this paper

• Anesthetic induction with propofol via continuous infusion or bolus in healthy dogs: a randomized clinical trial

  2026cites this paper
• Total intravenous anesthesia with Ketofol in rabbits: a comparison of the effects of constant rate infusion of midazolam, fentanyl or dexmedetomidine

  2024cites this paper
• Effects of Oxygen Supplementation on Injectable and Inhalant Anesthesia in C57BL/6 Mice.

  2021cites this paper
• Mouse Anesthesia: The Art and Science

  2021cites this paper
• Total intravenous anesthesia in domestic chicken (Gallus gallus domesticus) with propofol alone or in combination with methadone, nalbuphine or fentanyl for ulna osteotomy.

  2020cites this paper
• Effect of sevoflurane anesthesia on neuromuscular blockade produced by rocuronium infusion in dogs

  2019cites this paper
• MECANISMOS FISIOPATOLÓGICOS DA NOCICEPÇÃO E BASES DA ANALGESIA PERIOPERATÓRIA EM PEQUENOS ANIMAIS

  2017cites this paper