Exploring the role of hypoxia in neuroinflammatory disease and the use of oxygen as a therapy

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Unknown venue

• Publication date

  2017-02-28

• Fields of study

  Medicine, Environmental Science

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Cause and prevention of demyelination in a model multiple sclerosis lesion

  2016influential reference
• Disease-modifying therapies and infectious risks in multiple sclerosis

  2016influential reference
• Necroptosis and Inflammation.

  2016influential reference
• Phenytoin for neuroprotection in patients with acute optic neuritis: a randomised, placebo-controlled, phase 2 trial.

  2016cited by this paper
• Mitochondrial dysfunction is an important cause of neurological deficits in an inflammatory model of multiple sclerosis

  2016influential reference
• Movement and structure of mitochondria in oligodendrocytes and their myelin sheaths

  2016cited by this paper
• The mitochondrial permeability transition pore in AD 2016: An update.

  2016cited by this paper
• Microglial M1/M2 polarization and metabolic states

  2016cited by this paper
• Oxidative stress response to acute hypobaric hypoxia and its association with indirect measurement of increased intracranial pressure: a field study

  2016cited by this paper
• Hypoxia and Mucosal Inflammation.

  2016cited by this paper
• Harnessing the integrated stress response for the treatment of multiple sclerosis

  2016cited by this paper
• Characterization of glucose‐related metabolic pathways in differentiated rat oligodendrocyte lineage cells

  2015cited by this paper
• The unfolded protein response in multiple sclerosis

  2015cited by this paper
• Microglia and necroptosis: The culprits of neuronal cell death in multiple sclerosis.

  2015cited by this paper
• Neutrophil-related factors as biomarkers in EAE and MS

  2015influential reference
• Pathological mechanisms in progressive multiple sclerosis.

  2015influential reference
• Myelin Loss and Axonal Ion Channel Adaptations Associated with Gray Matter Neuronal Hyperexcitability

  2015cited by this paper
• Metabolic reprogramming in macrophages and dendritic cells in innate immunity

  2015cited by this paper
• Activation of necroptosis in multiple sclerosis.

  2015influential reference
• Role of the innate and adaptive immune responses in the course of multiple sclerosis.

  2015cited by this paper
• Does normobaric hyperoxia increase oxidative stress in acute ischemic stroke? A critical review of the literature

  2015cited by this paper
• Necroptosis and its role in inflammation

  2015cited by this paper
• Reduced cortical microvascular oxygenation in multiple sclerosis: a blinded, case-controlled study using a novel quantitative near-infrared spectroscopy method

  2015cited by this paper
• All the right moves: the need for the timely use of hyperbaric oxygen therapy for treating TBI/CTE/PTSD

  2015cited by this paper
• Cerebral Hypoperfusion: A New Pathophysiologic Concept in Multiple Sclerosis?

  2015influential reference
• State-ofthe-Art Methods for Evaluation of Angiogenesis and Tissue Vascularization

  2015cited by this paper
• Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis

  2014cited by this paper
• Thrombotic Processes in Multiple Sclerosis as Manifestation of Innate Immune Activation

  2014cited by this paper
• Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models

  2014influential reference
• Hyperbaric Oxygen Therapy in Acute Ischemic Stroke: A Review

  2014cited by this paper
• Molecular Mechanisms That Influence the Macrophage M1–M2 Polarization Balance

  2014cited by this paper
• Mitochondrial immobilization mediated by syntaphilin facilitates survival of demyelinated axons

  2014cited by this paper
• Phagocytosis of Microglia in the Central Nervous System Diseases

  2014cited by this paper
• Cerebrospinal fluid ceramides from patients with multiple sclerosis impair neuronal bioenergetics.

  2014cited by this paper
• Mitochondrial dysfunction contributes to neurodegeneration in multiple sclerosis.

  2014influential reference
• Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal

  2014cited by this paper
• Hemoglobin-based oxygen carriers: An update on their continued potential for military application

  2014cited by this paper
• Gender differences in autoimmune disease.

  2014cited by this paper
• Repetitive hypoxic preconditioning induces an immunosuppressed B cell phenotype during endogenous protection from stroke

  2014cited by this paper
• Cerebral Arterial Bolus Arrival Time is Prolonged in Multiple Sclerosis and Associated with Disability

  2014cited by this paper
• EGCG Attenuates Autoimmune Arthritis by Inhibition of STAT3 and HIF-1α with Th17/Treg Control

  2014cited by this paper
• Tumor-Associated Macrophages as Major Players in the Tumor Microenvironment

  2014influential reference
• Endoplasmic reticulum dysfunction in neurological disease.

  2013cited by this paper
• Polynitroxylated-Pegylated Hemoglobin Attenuates Fluid Requirements and Brain Edema in Combined Traumatic Brain Injury Plus Hemorrhagic Shock in Mice

  2013cited by this paper
• Regulation of the Hif-system by micro-RNA 17 and 20a - role during monocyte-to-macrophage differentiation.

  2013cited by this paper
• M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

  2013cited by this paper
• Extensive vascular remodeling in the spinal cord of pre-symptomatic experimental autoimmune encephalomyelitis mice; increased vessel expression of fibronectin and the α5β1 integrin.

  2013cited by this paper
• Oxidative stress, mitochondrial damage and neurodegenerative diseases

  2013cited by this paper
• Pathology and disease mechanisms in different stages of multiple sclerosis.

  2013influential reference
• Cerebral white matter blood flow and energy metabolism in multiple sclerosis

  2013cited by this paper
• The Evidence for Hypoperfusion as a Factor in Multiple Sclerosis Lesion Development

  2013cited by this paper
• Hypoxia-mediated regulation of macrophage functions in pathophysiology.

  2013cited by this paper
• Calreticulin and other components of endoplasmic reticulum stress in rat and human inflammatory demyelination

  2013cited by this paper
• What causes relapses of autoimmune diseases? The etiological role of autoreactive T cells.

  2013cited by this paper
• Apolipoprotein A‐I: Insights from redox proteomics for its role in neurodegeneration

  2013cited by this paper
• Chaperone machines for protein folding, unfolding and disaggregation

  2013cited by this paper
• Transcriptional control of macrophage polarization.

  2013cited by this paper
• Neurological deficits caused by tissue hypoxia in neuroinflammatory disease

  2013influential reference
• Pathology of Multiple Sclerosis: Where Do We Stand?

  2013cited by this paper
• Practical guide to the induction of relapsing progressive experimental autoimmune encephalomyelitis in the Biozzi ABH mouse.

  2012cited by this paper
• Pathogenic and regulatory roles for B cells in experimental autoimmune encephalomyelitis

  2012influential reference
• Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

  2012influential reference
• Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation

  2012cited by this paper
• Hypoxic preconditioning induces stroke tolerance in mice via a cascading HIF, sphingosine kinase, and CCL2 signaling pathway

  2012cited by this paper
• Oligodendroglia metabolically support axons and contribute to neurodegeneration

  2012cited by this paper
• Microglia activation along the corticospinal tract following traumatic brain injury in the rat: a neuroanatomical study.

  2012cited by this paper
• Glia: Oligodendrocyte transporters feed axons

  2012cited by this paper
• NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury

  2012influential reference
• Hypoxia-inducible factor-1 alpha–dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa

  2012cited by this paper
• Progressive multiple sclerosis: pathology and pathogenesis

  2012cited by this paper
• Nitric oxide (NO)--production and regulation of insulin secretion in islets of freely fed and fasted mice.

  2012cited by this paper
• Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation

  2012cited by this paper
• Neutrophils in multiple sclerosis are characterized by a primed phenotype.

  2012cited by this paper
• B cells in MS: Why, where and how?

  2012cited by this paper
• Increased expression of ER stress- and hypoxia-associated molecules in grey matter lesions in multiple sclerosis

  2012influential reference
• A hemoglobin-based multifunctional therapeutic: polynitroxylated pegylated hemoglobin.

  2012cited by this paper
• Neuroprotection and repair in multiple sclerosis

  2012cited by this paper
• Interferon-γ Activates Nuclear Factor-κ B in Oligodendrocytes through a Process Mediated by the Unfolded Protein Response

  2012cited by this paper
• Meningeal inflammation plays a role in the pathology of primary progressive multiple sclerosis.

  2012cited by this paper
• Adoptive Transfer of Immunomodulatory M2 Macrophages Prevents Type 1 Diabetes in NOD Mice

  2012cited by this paper
• Macrophage plasticity and polarization: in vivo veritas.

  2012cited by this paper
• Regulation of Oligodendrocyte Development and Myelination by Glucose and Lactate

  2011cited by this paper
• Vascular aspects of multiple sclerosis.

  2011cited by this paper
• Oxidative damage in multiple sclerosis lesions

  2011influential reference
• Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation.

  2011influential reference
• Polynitroxylated pegylated hemoglobin: A novel neuroprotective hemoglobin for acute volume-limited fluid resuscitation after combined traumatic brain injury and hemorrhagic hypotension in mice*

  2011cited by this paper
• Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models

  2011cited by this paper
• Chronic mild hypoxia ameliorates chronic inflammatory activity in myelin oligodendrocyte glycoprotein (MOG) peptide induced experimental autoimmune encephalomyelitis (EAE).

  2011cited by this paper
• Expression profiles of endoplasmic reticulum stress-related molecules in demyelinating lesions and multiple sclerosis

  2011influential reference
• Newly lesioned tissue in multiple sclerosis--a role for oxidative damage?

  2011cited by this paper
• The role(s) of astrocytes and astrocyte activity in neurometabolism, neurovascular coupling, and the production of functional neuroimaging signals

  2011cited by this paper
• Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool

  2011cited by this paper
• The molecular basis of neurodegeneration in multiple sclerosis

  2011cited by this paper
• Transcriptional regulation of macrophage polarization: enabling diversity with identity

  2011cited by this paper
• Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria

  2011influential reference
• Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

  2011cited by this paper
• Immunosuppression with FTY720 is insufficient to prevent secondary progressive neurodegeneration in experimental autoimmune encephalomyelitis

  2011cited by this paper
• Energy failure in multiple sclerosis and its investigation using MR techniques

  2011influential reference
• How do immune cells overcome the blood–brain barrier in multiple sclerosis?

  2011influential reference
• Angiogenesis is present in experimental autoimmune encephalomyelitis and pro-angiogenic factors are increased in multiple sclerosis lesions

  2010cited by this paper

• No citing papers are available for this paper.