Human skin mast cells express H2 and H4, but not H3 receptors.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of Investigative Dermatology

• Publication date

  2004-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/J.0022-202X.2004.22721.XPMID 15191551
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Histamine H4 Receptor Mediates Chemotaxis and Calcium Mobilization of Mast Cells

  2003cited by this paper
• IDENTIFICATION OF A HISTAMINE H4 RECEPTOR ON HUMAN EOSINOPHILS—ROLE IN EOSINOPHIL CHEMOTAXIS

  2002cited by this paper
• Expression and function of histamine receptors in human monocyte-derived dendritic cells.

  2002cited by this paper
• Expression and function of histamine receptors 1 and 2 on human monocyte-derived dendritic cells.

  2002cited by this paper
• Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow.

  2001cited by this paper
• Cloning and characterization of a novel human histamine receptor.

  2001cited by this paper
• Optimization of nucleated red blood cell (NRBC) recovery from maternal blood collected using both layers of a double density gradient

  2001cited by this paper
• Histamine regulates T-cell and antibody responses by differential expression of H1 and H2 receptors

  2001cited by this paper
• Inhibition of cytokine secretion from human leukemic mast cells and basophils by H1‐ and H2‐receptor antagonists

  2000cited by this paper
• alpha-Melanocyte stimulating hormone acts as a selective inducer of secretory functions in human mast cells.

  2000cited by this paper
• Molecular Cloning and Characterization of a Novel Type of Histamine Receptor Preferentially Expressed in Leukocytes*

  2000cited by this paper
• Molecular cloning and characterization of a new human histamine receptor, HH4R.

  2000cited by this paper
• Modulatory effect of imetit, a histamine H3 receptor agonist, on C-fibers, cholinergic fibers and mast cells in rabbit lungs in vitro.

  1999cited by this paper
• Differential effect of histamine 3 receptor-active agents on brain, but not peritoneal, mast cell activation.

  1999cited by this paper
• Cloning and functional expression of the human histamine H3 receptor.

  1999cited by this paper
• Beyond the histamine receptor: effect of antihistamines on mast cells

  1999cited by this paper
• Development of FUB 181, a Selective Histamine H3‐Receptor Antagonist of High Oral in Vivo Potency with 4‐(?gv‐(Arylalkyloxy)alkyl)‐1H‐imidazole Structure

  1998cited by this paper
• Histamine potently suppresses human IL-12 and stimulates IL-10 production via H2 receptors.

  1998cited by this paper
• Expression and functional activity of the IL-8 receptor type CXCR1 and CXCR2 on human mast cells.

  1998cited by this paper
• Detection of Intracellular Interleukin-8 in Human Mast Cells: Flow Cytometry as a Guide for Immunoelectron Microscopy

  1997cited by this paper
• Suppression of TNF-alpha secretion by azelastine in a rat mast (RBL-2H3) cell line: evidence for differential regulation of TNF-alpha release, transcription, and degranulation.

  1997cited by this paper
• Histamine inhibits tumor necrosis factor alpha release by mast cells through H2 and H3 receptors.

  1996cited by this paper
• Thrombin and melittin activate phospholipase C in human HaCaT keratinocytes

  1996cited by this paper
• Pharmacological modulation of IL‐6 and IL‐8 secretion by the H1‐antagonist decarboethoxy‐loratadine and dexamethasone by human mast and basophilic cell lines

  1995cited by this paper
• H1 and H2 histamine receptors in histiocytic lymphoma cell line U-937

  1995cited by this paper
• Autoregulation of histamine release via the histamine H3 receptor on mast cells in the rat skin.

  1994cited by this paper
• Molecular cloning of a gene encoding the histamine H2 receptor.

  1991cited by this paper
• Molecular cloning of a gene encoding the histamine H2 receptor.

  1991cited by this paper
• Localization of a 11.5 kDa Zn(2+)-binding protein (parathymosin) in different rat tissues. Cell type-specific distribution between cytosolic and nuclear compartment.

  1991cited by this paper
• The influence of H1-, H2- and H3-receptors on the spontaneous and ConA induced histamine release from human adenoidal mast cells

  1991cited by this paper
• Distribution, properties, and functional characteristics of three classes of histamine receptor.

  1990cited by this paper
• Establishment of an immature mast cell line from a patient with mast cell leukemia.

  1988cited by this paper
• Characterization of histamine H1-receptor binding peptides in guinea pig brain using [125I]iodoazidophenpyramine, an irreversible specific photoaffinity probe.

  1988cited by this paper
• Surface histamine receptors in rat peritoneal mast cells. Separation of receptor-bearing cells via binding to a histamineprotein conjugate, Cell-ectTM

  1984cited by this paper
• Use of antipeptide antibodies to demonstrate external orientation of the NH2-terminus of the low density lipoprotein receptor in the plasma membrane of fibroblasts

  1983cited by this paper
• A species comparison of the histamine H2-receptor on mast cells and basophils

  1982cited by this paper
• Evidence for H2-receptor-mediated inhibition of histamine release from isolated rat mast cells

  1982cited by this paper
• Histamine H-1 receptors on rat peritoneal mast cells.

  1982cited by this paper
• Pharmacological characterization of histamine receptors mediating the stimulation of cyclic AMP accumulation in slices from guinea-pig hippocampus.

  1978cited by this paper
• Inhibition of Histamine Release by Histamine controlled by H2 Receptor

  1973cited by this paper

• Histamine H3 and H4 Receptor Antagonists Differentially Inhibit Mast Cell Activation via FcεRI and MRGPRX2 Pathways

  2025cites this paper
• Histamine and TH2 cytokines regulate the biosynthesis of cysteinyl-leukotrienes and expression of their receptors in human mast cells

  2025cites this paper
• Histamine receptors in GtoPdb v.2025.3

  2025cites this paper
• Novel Insights on the Biology and Immunological Effects of Histamine: A Road Map for Allergists and Mast Cell Biologists.

  2024cites this paper
• Opportunities and challenges in the therapeutic exploitation of histamine and histamine receptor pharmacology in inflammation-driven disorders.

  2024cites this paper
• Histamine receptor agonism differentially induces immune and reparative healing responses in biomaterial-facilitated tissue repair.

  2024cites this paper
• Drug delivery targets and strategies to address mast cell diseases

  2023cites this paper
• Co-treatment with Fexofenadine and Budesonide Increases FoxP3 Gene Expression in Patients with Allergic Rhinitis

  2023cites this paper
• Association between histamine 2 receptor antagonists and sepsis outcomes in ICU patients: a retrospective analysis using the MIMI-IV database

  2023cites this paper
• Mast cell activation: beyond histamine and tryptase

  2023cites this paper
• Targeting IgE and Th2-Cytokines in Allergy: Brief Updates on Monoclonal Antibodies and Antibody Gene Therapy

  2023cites this paper
• Detection of histamine receptors on mouse oocytes and their involvement in fertilization potential

  2022cites this paper
• The Function of the Histamine H4 Receptor in Inflammatory and Inflammation-Associated Diseases of the Gut

  2021cites this paper
• Suppression of leukotriene B4 production is involved in the anti-pruritic action of Grifola frondosa in pollen allergy-induced ocular itching in mice

  2021cites this paper
• Histamine receptors in GtoPdb v.2021.3

  2021cites this paper
• Histamine in cancer immunology and immunotherapy. Current status and new perspectives

  2021cites this paper
• Prophylactic or therapeutic administration of Holarrhena floribunda hydro ethanol extract suppresses complete Freund’s adjuvant-induced arthritis in Sprague-Dawley rats

  2020cites this paper
• The interplay between mast cells, pineal gland, and circadian rhythm: Links between histamine, melatonin, and inflammatory mediators

  2020cites this paper
• Histamine-mediated autocrine signaling in mesenteric perilymphatic mast cells.

  2020cites this paper
• Beyond IgE: Alternative Mast Cell Activation Across Different Disease States

  2020cites this paper
• The Possible Uses and Challenges of Nanomaterials in Mast Cell Research

  2020cites this paper
• Commentary: Pathophysiological Role of Histamine H4 Receptor in Cancer: Therapeutic Implications

  2020cites this paper
• The KAAACI/KDA Evidence-Based Practice Guidelines for Chronic Spontaneous Urticaria in Korean Adults and Children: Part 1. Definition, Methodology and First-line Management

  2020cites this paper
• COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms

  2020cites this paper
• Scar Symptoms: Pruritus and Pain

  2020cites this paper
• Pharmacology of Histamine, Its Receptors and Antagonists in the Modulation of Physiological Functions

  2020cites this paper
• Histamine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

  2019cites this paper
• Expression of Histidine Decarboxylase and Its Roles in Inflammation

  2019cites this paper
• 2 Expression of the Histamine H 4 Receptor in Human Tissue

  2018cites this paper
• Silencing of H4R inhibits the production of IL-1β through SAPK/JNK signaling in human mast cells

  2018cites this paper
• Human eosinophils and mast cells: Birds of a feather flock together

  2018cites this paper
• Human mast cells and basophils—How are they similar how are they different?

  2018cites this paper
• Contribution à l'étude de l'effet de la substance P sur la sécrétion d'aldostérone dans la glande surrénale humaine normale

  2018cites this paper
• Role of Histamine in Inflammatory Diseases

  2018cites this paper
• THE IMPACT OF HISTAMINE RECEPTOR 2 ANTAGONISTS ON BREAST CANCER DEVELOPMENT AND MONOCYTIC POPULATIONS

  2018cites this paper
• Histamine H4 receptor mediates chemotaxis of human lung mast cells

  2018cites this paper
• The Role of Histamine and Histamine Receptors in Mast Cell-Mediated Allergy and Inflammation: The Hunt for New Therapeutic Targets

  2018influential citation
• Role of mast cells and basophils in pruritus

  2018cites this paper
• The role and relevance of mast cells in urticaria

  2018cites this paper
• Histamine H4 Receptor in Allergic Dermatitis

  2017cites this paper
• Histamine therapeutic efficacy in metastatic melanoma: Role of histamine H4 receptor agonists and opportunity for combination with radiation

  2017cites this paper
• Leukotriene receptor expression in mast cells is affected by their agonists.

  2017cites this paper
• Antinociceptive effect of co-administered NMDA and histamine H4 receptor antagonists in a rat model of acute pain

  2017cites this paper
• Mast cell and eosinophil surface receptors as targets for anti‐allergic therapy

  2017cites this paper
• Expression and localization of histamine H1, H2, and H3 receptors in rat olfactory epithelium.

  2017cites this paper
• The histamine H4-receptor and the central and peripheral nervous system: A critical analysis of the literature.

  2016cites this paper
• Phenotypic variability in human skin mast cells

  2016cites this paper
• Anatomy and Function of the Skin

  2016cites this paper
• The Role of Histamine H4 Receptor in Asthma and Atopic Dermatitis

  2016cites this paper
• Role of the Histamine H3 Receptor in the Central Nervous System.

  2016cites this paper
• International Union of Basic and Clinical Pharmacology. XCVIII. Histamine Receptors

  2015cites this paper
• Improving flow cytometric methodology for blood cell functional analysis

  2015cites this paper
• BODIPY® FL histamine as a new modality for quantitative detection of histamine receptor upregulation upon IgE sensitization in murine bone marrow‐derived mast cells

  2015influential citation
• Proinflammatory role of the histamine H4 receptor in dextrane sodium sulfate-induced acute colitis.

  2015cites this paper
• Mast cells in bacterial infections

  2014cites this paper
• Receptors, cells and circuits involved in pruritus of systemic disorders.

  2014cites this paper
• Histamine H4-receptor expression in the brain?

  2014cites this paper
• Functional characterization of histamine H4 receptor on human mast cells.

  2014cites this paper
• Granule maturation in mast cells: Histamine in control

  2014cites this paper
• [Expression and function of the histamine receptors in dermal and articular tissues].

  2014cites this paper
• Molecular targets on mast cells and basophils for novel therapies.

  2014cites this paper
• Chapter Ten - H4 Receptor Antagonists and Their Potential Therapeutic Applications

  2014cites this paper
• Peripheral Neuronal Mechanism of Itch: Histamine and Itch

  2014cites this paper
• Mast cell transcriptome elucidation: what are the implications for allergic disease in the clinic and where do we go next?

  2014cites this paper
• The role of histamine H 4 receptors as a potential targets in allergic rhinitis and asthma

  2013cites this paper
• Histamine Receptors and Inflammatory Cells

  2013influential citation
• Molecular and cellular analysis of human histamine receptor subtypes.

  2013cites this paper
• Histamine in Atopic Disorders: Atopic Dermatitis and Pruritus

  2013cites this paper
• Role of Histamine and Histamine H 4 Receptor in Inflammatory Skin Diseases in Man

  2013cites this paper
• The role of histamine H4 receptors as a potential targets in allergic rhinitis and asthma

  2013cites this paper
• Review paper Stem cell factor-dependent mast cell proliferation, maturation and activity can be regulated by inhibitory receptors

  2013cites this paper
• Histamine H4 receptor ligands

  2013cites this paper
• Expression of the Histamine H4 Receptor in Human Tissue

  2012cites this paper
• The role of mast cell proteases in allergic disease and apoptosis

  2012cites this paper
• Involvement of leukotriene B4 in itching in a mouse model of ocular allergy.

  2012cites this paper
• Histamine H2-receptor antagonists for urticaria.

  2012cites this paper
• Histamine contributes to increased RANKL to osteoprotegerin ratio through altered nuclear receptor 4A activity in human chondrocytes.

  2012cites this paper
• H₄ receptors in mast cells and basophils: a new therapeutic target for allergy?

  2012cites this paper
• Differential regulation of T cell responses by pathogenic and apathogenic microorganisms

  2012cites this paper
• Novel Identified Receptors on Mast Cells

  2012cites this paper
• Strain‐dependent effects of the histamine H4 receptor antagonist JNJ7777120 in a murine model of acute skin inflammation

  2012cites this paper
• Hydroxyzine, cimetidine and vitamin C in reducing skin flap necrosis in ischemia-reperfusion injury in rats. A comparative study.

  2012cites this paper
• Histamine-Releasing and Allergenic Properties of Opioid Analgesic Drugs: Resolving the Two

  2012cites this paper
• Histamine H3 receptor as a drug discovery target.

  2011cites this paper
• Pharmacology of Antihistamines

  2011cites this paper
• Targeting the histamine H4 receptor.

  2011cites this paper
• Molecular modelling study on human histamine H1 receptor and its applications in virtual lead identification for designing novel inverse agonists

  2011cites this paper
• The expression of histamine H4 receptor mRNA in the skin and other tissues of normal dogs.

  2011cites this paper
• Role of H4 receptor in histamine-mediated responses in human melanoma

  2011cites this paper
• Pathogenetic and therapeutic implications of the histamine H4 receptor in inflammatory skin diseases and pruritus.

  2011cites this paper
• Biomedical Aspects of Histamine

  2011cites this paper
• Insights into the physiomodulatory role of histaminergic receptors in vertebrate skin pigmentation

  2011cites this paper
• Histamine: New Thoughts About a Familiar Mediator

  2011cites this paper
• Histamine as an immunomodulator

  2010cites this paper
• Immune Regulation by Various Facets of Histamine in Immunomodulation and Allergic Disorders

  2010cites this paper
• Histamine-Cytokine and Histamine-Antibody Network in Immune Regulation

  2010cites this paper
• Up-Regulation of Histamine H4 Receptors Contributes to Splenic Apoptosis in Septic Mice: Counteraction of the Antiapoptotic Action of Nuclear Factor-κB

  2010cites this paper
• Histamine H4 receptor: a novel therapeutic target for immune and allergic responses.

  2010cites this paper
• Mast cell function in physiology and pathophysiology

  2010cites this paper
• Expression of Histamine H4 Receptor in Human Synovial Cells and Dermal Tissues

  2010cites this paper