On the origin and growth of gliomas.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Anticancer Research

• Publication date

  2010-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 20651342
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The hallmarks of cancer

  2012cited by this paper
• Stem cells as vectors to deliver HSV/tk gene therapy for malignant gliomas.

  2009cited by this paper
• Distinct pools of cancer stem-like cells coexist within human glioblastomas and display different tumorigenicity and independent genomic evolution

  2009cited by this paper
• Donor-Derived Brain Tumor Following Neural Stem Cell Transplantation in an Ataxia Telangiectasia Patient

  2009cited by this paper
• NHERF-1: modulator of glioblastoma cell migration and invasion.

  2009cited by this paper
• Neural stem cells target intracranial glioma to deliver an oncolytic adenovirus in vivo

  2009cited by this paper
• Spontaneous In Vitro Transformation of Adult Neural Precursors into Stem‐Like Cancer Cells

  2009cited by this paper
• Gliotypic Neural Stem Cells Transiently Adopt Tumorigenic Properties During Normal Differentiation

  2009cited by this paper
• Novel treatment strategies for malignant gliomas using neural stem cells

  2009cited by this paper
• Stem cell-related "self-renewal" signature and high epidermal growth factor receptor expression associated with resistance to concomitant chemoradiotherapy in glioblastoma.

  2008cited by this paper
• CD133 identifies perivascular niches in grade II–IV astrocytomas

  2008cited by this paper
• Expression of Multidrug Resistance Genes in Normal and Cancer Stem Cells

  2008cited by this paper
• Gliomagenesis and neural stem cells: Key role of hypoxia and concept of tumor "neo-niche".

  2008cited by this paper
• The Cancer Stem Cell–Vascular Niche Complex in Brain Tumor Formation

  2008cited by this paper
• Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors.

  2008cited by this paper
• Identification of A2B5+CD133- tumor-initiating cells in adult human gliomas.

  2008cited by this paper
• Glial Progenitor-Like Phenotype in Low-Grade Glioma and Enhanced CD133-Expression and Neuronal Lineage Differentiation Potential in High-Grade Glioma

  2008cited by this paper
• Hematopoietic Stem Cell–Derived Pericytic Cells in Brain Tumor Angio-Architecture

  2008cited by this paper
• Glioma stem cells: a midterm exam.

  2008cited by this paper
• The prognostic value of nestin expression in newly diagnosed glioblastoma: Report from the Radiation Therapy Oncology Group

  2008cited by this paper
• Epidermal Growth Factor Plays a Crucial Role in Mitogenic Regulation of Human Brain Tumor Stem Cells*

  2008cited by this paper
• Molecular Cancer BioMed Central

  2008cited by this paper
• Clinical and biological implications of CD133-positive and CD133-negative cells in glioblastomas

  2008cited by this paper
• A role for glutamate in growth and invasion of primary brain tumors

  2008cited by this paper
• Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

  2008cited by this paper
• Characterization of Adult Neural Stem Cells and Their Relation to Brain Tumors

  2008cited by this paper
• Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria

  2008cited by this paper
• CD133 Expression and Cancer Stem Cells Predict Prognosis in High‐grade Oligodendroglial Tumors

  2008cited by this paper
• c-Myc Is Required for Maintenance of Glioma Cancer Stem Cells

  2008cited by this paper
• Glioma stem cells are more aggressive in recurrent tumors with malignant progression than in the primary tumor, and both can be maintained long-term in vitro

  2008cited by this paper
• The heterogeneity of adult neural stem cells and the emerging complexity of their niche.

  2008cited by this paper
• Cancer stem cells and survival pathways

  2008cited by this paper
• Stem Cells and the Origin and Propagation of Brain Tumors

  2008cited by this paper
• A COMPARISON BETWEEN STEM CELLS FROM THE ADULT HUMAN BRAIN AND FROM BRAIN TUMORS

  2008cited by this paper
• Migration of human neural stem cells toward an intracranial glioma

  2008cited by this paper
• Stem Cell Marker CD133 Affects Clinical Outcome in Glioma Patients

  2008cited by this paper
• Neural Stem Cell Tropism to Glioma: Critical Role of Tumor Hypoxia

  2008cited by this paper
• The Antitumorigenic Response of Neural Precursors Depends on Subventricular Proliferation and Age

  2008cited by this paper
• Nestin and CD133: valuable stem cell-specific markers for determining clinical outcome of glioma patients

  2008cited by this paper
• Induction of oligodendrocyte differentiation by Olig2 and Sox10: evidence for reciprocal interactions and dosage-dependent mechanisms.

  2007cited by this paper
• Tumor Growth Need Not Be Driven by Rare Cancer Stem Cells

  2007cited by this paper
• Multi‐directional differentiation of doublecortin‐ and NG2‐immunopositive progenitor cells in the adult rat neocortex in vivo

  2007cited by this paper
• Targeting brain-tumor stem cells

  2007cited by this paper
• Spheres Isolated from 9L Gliosarcoma Rat Cell Line Possess Chemoresistant and Aggressive Cancer Stem‐Like Cells

  2007cited by this paper
• Brain tumour stem cells: possibilities of new therapeutic strategies

  2007cited by this paper
• Resilience to transformation and inherent genetic and functional stability of adult neural stem cells ex vivo.

  2007cited by this paper
• Astrocytic stem cells in the adult brain.

  2007cited by this paper
• CD133 is not present on neurogenic astrocytes in the adult subventricular zone, but on embryonic neural stem cells, ependymal cells, and glioblastoma cells.

  2007cited by this paper
• Malignant astrocytic glioma: genetics, biology, and paths to treatment.

  2007cited by this paper
• CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles.

  2007cited by this paper
• Stem cells tropism for malignant gliomas

  2007cited by this paper
• Neural stem cells as biological minipumps: a faster route to cell therapy for the CNS?

  2007cited by this paper
• The human subventricular zone: a source of new cells and a potential source of brain tumors.

  2007cited by this paper
• Making a tumour's bed: glioblastoma stem cells and the vascular niche

  2007cited by this paper
• Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization.

  2007cited by this paper
• The biology ofAstrocytoma: Lessons learned from chronic myelogenous leukemia—hypothesis

  2007cited by this paper
• Cancer stem cells as mediators of treatment resistance in brain tumors: status and controversies.

  2007cited by this paper
• Neural stem cell markers, nestin and musashi proteins, in the progression of human glioma: correlation of nestin with prognosis of patient survival.

  2007cited by this paper
• Malignant gliomas actively recruit bone marrow stromal cells by secreting angiogenic cytokines

  2007cited by this paper
• A perivascular niche for brain tumor stem cells.

  2007cited by this paper
• Instructive cross‐talk between neural progenitor cells and gliomas

  2007cited by this paper
• Expression of stem cell markers in human astrocytomas of different WHO grades

  2007cited by this paper
• Platelet-derived growth factor-mediated gliomagenesis and brain tumor recruitment.

  2007cited by this paper
• Most C6 cells are cancer stem cells: evidence from clonal and population analyses.

  2007cited by this paper
• Primary Glioblastomas Express Mesenchymal Stem-Like Properties

  2006cited by this paper
• Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells

  2006cited by this paper
• In vitro identification and functional characterization of glial precursor cells in human gliomas

  2006cited by this paper
• Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

  2006cited by this paper
• Differentiation profile of brain tumor stem cells: a comparative study with neural stem cells

  2006cited by this paper
• Modeling the neurovascular niche: VEGF‐ and BDNF‐mediated cross‐talk between neural stem cells and endothelial cells: An in vitro study

  2006cited by this paper
• Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis.

  2006cited by this paper
• Chemokine-directed migration of tumor-inhibitory neural progenitor cells towards an intracranially growing glioma.

  2006cited by this paper
• Identifying cancer stem cells in solid tumors: case not proven.

  2006cited by this paper
• Bone morphogenetic protein signal transduction in bone.

  2006cited by this paper
• Glial Progenitors in Adult White Matter Are Driven to Form Malignant Gliomas by Platelet-Derived Growth Factor-Expressing Retroviruses

  2006cited by this paper
• Notch signaling enhances nestin expression in gliomas.

  2006cited by this paper
• The duality of epidermal growth factor receptor (EGFR) signaling and neural stem cell phenotype: cell enhancer or cell transformer?

  2006cited by this paper
• Stem cells of ependymoma

  2006cited by this paper
• Mathematical model for the cancer stem cell hypothesis

  2006cited by this paper
• Nestin expression in neuroepithelial tumors.

  2006cited by this paper
• Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor.

  2006cited by this paper
• Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

  2006cited by this paper
• Brain tumour stem cells

  2006cited by this paper
• Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines.

  2006cited by this paper
• The epigenetic progenitor origin of human cancer

  2006cited by this paper
• PDGFRα-Positive B Cells Are Neural Stem Cells in the Adult SVZ that Form Glioma-like Growths in Response to Increased PDGF Signaling

  2006cited by this paper
• Bone morphogenetic protein signal transduction in bone

  2006cited by this paper
• Lessons from the bone marrow: how malignant glioma cells attract adult haematopoietic progenitor cells.

  2005cited by this paper
• More than just proliferation: Myc function in stem cells.

  2005cited by this paper
• Cancer stem cells: lessons from leukemia.

  2005cited by this paper
• Glioma therapy and real‐time imaging of neural precursor cell migration and tumor regression

  2005cited by this paper
• Radial 'glial' progenitors: neurogenesis and signaling.

  2005cited by this paper
• Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster

  2005cited by this paper
• Glioblastoma-Induced Attraction of Endogenous Neural Precursor Cells Is Associated with Improved Survival

  2005cited by this paper
• Bone marrow as a source of circulating CXCR4+ tissue‐committed stem cells

  2005cited by this paper
• Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas.

  2005cited by this paper
• Olig2 Directs Astrocyte and Oligodendrocyte Formation in Postnatal Subventricular Zone Cells

  2005cited by this paper
• Neural stem cells and neurospheres—re-evaluating the relationship

  2005cited by this paper
• PEX-Producing Human Neural Stem Cells Inhibit Tumor Growth in a Mouse Glioma Model

  2005cited by this paper
• Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation.

  2005cited by this paper

• Overcoming brain barriers through surface-functionalized liposomes for glioblastoma therapy; current status, challenges and future perspective.

  2024cites this paper
• Numerical solution for a fractional operator-based mathematical model of a brain tumour

  2024cites this paper
• Targeting the undruggable in glioblastoma using nano-based intracellular drug delivery

  2024cites this paper
• Ultrasmall solid lipid nanoparticles as a potential innovative delivery system for a drug combination against glioma.

  2024cites this paper
• DTI Abnormalities Related to Glioblastoma: A Prospective Comparative Study with Metastasis and Healthy Subjects

  2022cites this paper
• Harnessing oxidative stress for anti-glioma therapy.

  2022cites this paper
• PDA-Based Drug Delivery Nanosystems: A Potential Approach for Glioma Treatment

  2022cites this paper
• Emerging biomarker in carcinogenesis. Focus on Nestin

  2022cites this paper
• Implications of Cellular Immaturity in Necrosis and Microvascularization in Glioblastomas IDH-Wild-Type

  2022cites this paper
• Phenocopying Glioblastoma: A Review

  2021cites this paper
• Overcoming the Blood–Brain Barrier: Successes and Challenges in Developing Nanoparticle-Mediated Drug Delivery Systems for the Treatment of Brain Tumours

  2020cites this paper
• Superparamagnetic iron oxide nanoparticles drive miR-485-5p inhibition in glioma stem cells by silencing Tie1 expression

  2020cites this paper
• Methotrexate-Loaded Solid Lipid Nanoparticles: Protein Functionalization to Improve Brain Biodistribution

  2019cites this paper
• Ectopic expression of L1CAM ectodomain alters differentiation and motility, but not proliferation, of human neural progenitor cells

  2019cites this paper
• Hypoxia of Rats Subjected to Carotid Artery Ligation Results in Impaired Neurogenesis and Reduced Number of Cortical Neurons

  2019cites this paper
• Enhancement of malignant properties of human glioma cells by ganglioside GD3/GD2.

  2018cites this paper
• Wnt pathway co-factors TCF1 and TCF4 control glioblastoma phenotype through an oxygen-dependent mechanism

  2017cites this paper
• Applying Adomian Decomposition Method to Solve Burgess Equation with a Non-linear Source

  2016cites this paper
• Chapter 2 Stem-Like Adherent Cells Isolated and Cultured from Glioblastoma Multiforme

  2016cites this paper
• Magnetofection Based on Superparamagnetic Iron Oxide Nanoparticles Weakens Glioma Stem Cell Proliferation and Invasion by Mediating High Expression of MicroRNA-374a

  2016influential citation
• Early Differentiating Mouse Astroglial Progenitors Share Common Protein Signatures with GL261 Glioma Cells

  2016cites this paper
• Nestin+cells forming spheroids aggregates resembling tumorspheres in experimental ENU-induced gliomas.

  2016cites this paper
• Sox2: regulation of expression and contribution to brain tumors.

  2016cites this paper
• Distribution and Effects of CDKN2 p16 540 C>G and 580 C>T, and MDM2 SNP309 T>G Polymorphisms in Patients with Primary Brain Tumors.

  2015cites this paper
• Applying Adomian Decomposition Method to Solve Burgess Equation with a Non-linear Source

  2015cites this paper
• Applying Adomian Decomposition Method to Solve Burgess Equation with a Non-linear Source

  2015cites this paper
• Reconsideration of the clinical and histopathological significance of angiogenesis in prostate cancer: Usefulness and limitations of microvessel density measurement

  2015cites this paper
• On the Genesis of Neuroblastoma and Glioma

  2015cites this paper
• Response to Re: Reconsideration of the clinical and histopathological significance of angiogenesis in prostate cancer: Usefulness and limitations of microvessel density measurement

  2015cites this paper
• On the Genesis of Neuroblastoma and Glioma

  2014cites this paper
• Cells Isolated from Human Glioblastoma Multiforme Express Progesterone-Induced Blocking Factor (PIBF)

  2014influential citation
• Role of Receptor Tyrosine Kinases and Their Ligands in Glioblastoma

  2014cites this paper
• Spatial Relationships of MR Imaging and Positron Emission Tomography with Phenotype, Genotype and Tumor Stem Cell Generation in Glioblastoma Multiforme

  2014cites this paper
• Distinctive effects of the cellular inhibitor of apoptosis protein c-IAP2 through stabilization by XIAP in glioblastoma multiforme cells

  2014cites this paper
• Cancer stem cells from glioblastoma multiforme: culturing and phenotype

  2014cites this paper
• Barriers and a Subpopulation of Astroglial Progenitors of Developing Human Forebrain Are

  2014cites this paper
• Brain Barriers and a Subpopulation of Astroglial Progenitors of Developing Human Forebrain Are Immunostained for the Glycoprotein YKL-40

  2014cites this paper
• Solid lipid nanoparticles for potential doxorubicin delivery in glioblastoma treatment: preliminary in vitro studies.

  2014cites this paper
• Involvement of intermediate filament nestin in cell growth of small-cell lung cancer.

  2013cites this paper
• Nestin: Neural Stem/Progenitor Cell Marker in Brain Tumors

  2013cites this paper
• DNA Demethylating Agents Synergize with Oncolytic HSV1 against Malignant Gliomas

  2013cites this paper
• Inhibition of SUR1 decreases the vascular permeability of cerebral metastases.

  2013cites this paper
• Nestin: a novel angiogenesis marker and possible target for tumor angiogenesis.

  2013cites this paper
• Angiogenic Signalling Pathways Altered in Gliomas: Selection Mechanisms for More Aggressive Neoplastic Subpopulations with Invasive Phenotype

  2012cites this paper
• Glioblastoma cancer stem cells: Basis for a functional hypothesis

  2012cites this paper
• Development of a Unique Small Molecule Modulator of CXCR4

  2012cites this paper
• HES6 gene is selectively overexpressed in glioma and represents an important transcriptional regulator of glioma proliferation

  2012cites this paper
• Low Concentration Microenvironments Enhance the Migration of Neonatal Cells of Glial Lineage

  2012cites this paper
• Expression of transforming growth factor-β1 (TGF-β1) and E-cadherin in glioma

  2012cites this paper
• Low Concentration Microenvironments Enhance the Migration of Neonatal Cells of Glial Lineage

  2012cites this paper
• Mislocalization of the exitatory amino-acid transporters (EAATs) in human astrocytoma and non-astrocytoma cancer cells: effect of the cell confluence

  2012cites this paper
• SOX2 expression and amplification in gliomas and glioma cell lines.

  2011cites this paper
• SOX 2 Expression and Amplification in Gliomas and Glioma Cell Lines

  2011cites this paper
• Antigenic and Genotypic Similarity between Primary Glioblastomas and Their Derived Neurospheres

  2011cites this paper
• Molecular heterogeneity in glioblastoma: therapeutic opportunities and challenges.

  2011cites this paper
• Proteolysis of the matricellular protein hevin by matrix metalloproteinase‐3 produces a SPARC‐like fragment (SLF) associated with neovasculature in a murine glioma model

  2011cites this paper
• The Brain Adjacent to Tumor (BAT)

  2011cites this paper
• Endogenous Experimental Glioma Model, Links Between Glioma Stem Cells and Angiogenesis

  2011influential citation
• Effects of ectopic expression of the L1CAM long ectodomain in astrotypic human neural progenitor cells on motility, proliferation and differentiation

  2011cites this paper
• The molecular role of non-canonical Notch signaling via Deltex-1 in high grade glioma

  2011cites this paper
• The Anti-tumor Effects of Vitamin D in Other Cancers

  2011cites this paper
• Cellules stromales mésenchymateuses comme vecteurs cellulaires de nanoparticules : un nouvel outil thérapeutique des tumeurs cérébrales

  2010influential citation
• Utilisation des cellules souches mésenchymateuses humaines pour la thérapie cellulaire anti-cancéreuse dans un modèle de glioblastome

  2010cites this paper