Final results of a phase IIa, randomised, open-label trial to evaluate the percutaneous intramyocardial transplantation of autologous skeletal myoblasts in congestive heart failure patients: the SEISMIC trial.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  EuroIntervention

• Publication date

  2011-02-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.4244/EIJV6I7A139PMID 21252013
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• One-year follow-up of feasibility and safety of the first U.S., randomized, controlled study using 3-dimensional guided catheter-based delivery of autologous skeletal myoblasts for ischemic cardiomyopathy (CAuSMIC study).

  2009cited by this paper
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  2008cited by this paper
• Skeletal myoblasts and cardiac repair.

  2008cited by this paper
• Paracrine effects of transplanted myoblasts and relaxin on post-infarction heart remodelling

  2007cited by this paper
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  2006cited by this paper
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  2005cited by this paper
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  2005cited by this paper
• Functional assessment of myoblast transplantation for cardiac repair with magnetic resonance imaging

  2005cited by this paper
• Transplantation of skeletal myoblasts for cardiac repair.

  2004cited by this paper
• Transcatheter Transplantation of Autologous Skeletal Myoblasts in Postinfarction Patients with Severe Left Ventricular Dysfunction

  2004cited by this paper
• Autologous skeletal myoblast transplantation for severe postinfarction left ventricular dysfunction.

  2003cited by this paper
• Myocyte and myogenic stem cell transplantation in the heart.

  2003cited by this paper
• Catheter-based intramyocardial injection of autologous skeletal myoblasts as a primary treatment of ischemic heart failure: clinical experience with six-month follow-up.

  2003influential reference
• World Wide Web at:

  2001cited by this paper

• Safety and Efficacy of Transendocardial Stem Cells Therapy in Chronic Ischemic Heart Failure: A Systematic Review and Meta-analysis of Randomized Controlled Trials

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• Standardisation is the key to the sustained, rapid and healthy development of stem cell‐based therapy

  2024cites this paper
• Stem cell and exosome therapies for regenerating damaged myocardium in heart failure.

  2024cites this paper
• EML-PSP: A novel ensemble machine learning-based physical security paradigm using cross-domain ultra-fused feature extraction with hybrid data augmentation scheme

  2024cites this paper
• An Approach That Brings Out the Potential of Regenerative Therapies in Heart Failure.

  2023cites this paper
• Therapeutic use of Stem Cells, Blood and Bone Marrow Products

  2023cites this paper
• Meta-Analysis of Percutaneous Endomyocardial Cell Therapy in Patients with Ischemic Heart Failure by Combination of Individual Patient Data (IPD) of ACCRUE and Publication-Based Aggregate Data

  2022cites this paper
• Stem Cell Differentiation into Cardiomyocytes: Current Methods and Emerging Approaches

  2022cites this paper
• Impact of procedural variability and study design quality on the efficacy of cell-based therapies for heart failure - a meta-analysis

  2022cites this paper
• Contemporary Challenges of Regenerative Therapy in Patients with Ischemic and Non-Ischemic Heart Failure

  2022cites this paper
• Effectiveness of Stem Cell Therapies in Improving Clinical Outcomes in Patients With Heart Failure

  2021influential citation
• Current Status of Stem Cell Therapy and Nanofibrous Scaffolds in Cardiovascular Tissue Engineering

  2021cites this paper
• Stem Cells in Cardiovascular Diseases: 30,000-Foot View

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• Global position paper on cardiovascular regenerative medicine

  2020cites this paper
• Growth factor therapy for cardiac repair: an overview of recent advances and future directions

  2020cites this paper
• Can Stem Cells Improve Left Ventricular Ejection Fraction in Heart Failure? A Literature Review of Skeletal Myoblasts and Bone Marrow-Derived Cells

  2020cites this paper
• Clinical safety profile of transendocardial catheter injection systems: A plea for uniform reporting.

  2020cites this paper
• Biomedical applications of muscle-derived stem cells: from bench to bedside

  2020cites this paper
• First-in-human PeriCord cardiac bioimplant: Scalability and GMP manufacturing of an allogeneic engineered tissue graft

  2020cites this paper
• Robust Cardiac Regeneration: Fulfilling the Promise of Cardiac Cell Therapy.

  2020cites this paper
• Stem Cells in Cardiovascular Medicine: Historical Overview and Future Prospects

  2019cites this paper
• Stem cells as therapy for heart disease: iPSCs, ESCs, CSCs, and skeletal myoblasts.

  2019cites this paper
• Beyond pharmacological treatment: an insight into therapies that target specific aspects of heart failure pathophysiology.

  2019cites this paper
• EVALUATION THE ROLE OF SKELETAL MYOBLASTS IN THE MANAGEMENT OF ISCHEMIC HEART DISEASE

  2019cites this paper
• Autologous Skeletal Myoblast/Mononuclear Bone Marrow Cell Transplantation

  2019cites this paper
• A meta‐analysis of arrhythmia endpoints in randomized controlled trials of transendocardial stem cell injections for chronic ischemic heart disease

  2019cites this paper
• Cell Therapy for Heart Disease: Ready for Prime Time or Lost in Translation?

  2019cites this paper
• Autologous Cell Therapy for Cardiac and Peripheral Arterial Disease

  2018cites this paper
• Adult Stem Cells for Regenerative Therapy.

  2018cites this paper
• Myocardial regeneration therapy in heart failure: Current status and future therapeutic implications in clinical practice.

  2018cites this paper
• Emerging Therapies for Congestive Heart Failure

  2018cites this paper
• Clinical treatment of heart failure by adult stem cells: existing problems and prospects

  2018cites this paper
• Endothelial and cardiac progenitor cells for cardiovascular repair: A controversial paradigm in cell therapy

  2018cites this paper
• Pluripotent and Mesenchymal Stem Cells—Challenging Sources for Derivation of Myoblast

  2018cites this paper
• Stem Cell Therapy in Heart Diseases – Cell Types, Mechanisms and Improvement Strategies

  2018cites this paper
• Cellular therapies for chronic ischemic heart failure.

  2018cites this paper
• Global position paper on cardiovascular regenerative medicine TACTICS (Transnational Alliance for Regenerative Therapies in Cardiovascular Syndromes)

  2018cites this paper
• 30 – Cardiac Remodeling and Regeneration

  2018cites this paper
• Cell-enriched engineered cardiac grafts improve heart function and promote cardiac regeneration: a novel therapy for myocardial infarction

  2017cites this paper
• Safety, feasibility and effectiveness of first in‐human administration of muscle‐derived stem/progenitor cells modified with connexin‐43 gene for treatment of advanced chronic heart failure

  2017cites this paper
• Global position paper on cardiovascular regenerative medicine

  2017cites this paper
• Optimal Delivery Strategy for Stem Cell Therapy in Patients with Ischemic Heart Disease

  2017cites this paper
• Striated muscle function, regeneration, and repair

  2016influential citation
• Current State of Stem Cell Therapy for Ischemic Heart Disease

  2016cites this paper
• Clinical Benefits of Stem Cells for Chronic Symptomatic Systolic Heart Failure: A Systematic Review of the Existing Data and Ongoing Trials

  2016cites this paper
• Clinical efficacy of water extract of stem bark of Terminalia arjuna (Roxb. ex DC.) Wight & Arn. in patients of chronic heart failure: a double-blind, randomized controlled trial.

  2016cites this paper
• Mechanisms behind stem cell therapy in acute myocardial infarction

  2016cites this paper
• Stem cell therapies for congenital heart disease.

  2016cites this paper
• Cellular Therapy for Heart Failure

  2016cites this paper
• 13 – Harnessing Anaerobic Nature of Stem Cells for Use in Regenerative Medicine

  2016cites this paper
• A New In Vitro Co‐Culture Model Using Magnetic Force‐Based Nanotechnology

  2016cites this paper
• Clinical Trials Using Cell-based Therapy in Ischemic Heart Diseases - ADecadeâÂÂs Efforts

  2015cites this paper
• Current Concepts in Stem Cell Therapy for Cardiovascular Diseases: What We Know and Don't Know

  2015cites this paper
• Meta-analysis of cell therapy trials for patients with heart failure.

  2015cites this paper
• Cellular Cardiomyoplasty Using Skeletal Muscle Stem Cells

  2015cites this paper
• Endpoints in stem cell trials in ischemic heart failure

  2015cites this paper
• Devices for stem cell isolation and delivery: current need for drug discovery and cell therapy

  2015cites this paper
• Stem cell therapy for chronic heart failure

  2015cites this paper
• Safety and Efficacy of Autologous Skeletal Myoblast Sheets (TCD-51073) for the Treatment of Severe Chronic Heart Failure Due to Ischemic Heart Disease.

  2015cites this paper
• Cell‐based therapies for cardiac disease: a cellular therapist's perspective

  2015cites this paper
• Extending flaps lifts an infarcted heart toward repair.

  2015cites this paper
• Feasibility Study of Particulate Extracellular Matrix (P-ECM) and Left Ventricular Assist Device (HVAD) Therapy in Chronic Ischemic Heart Failure Bovine Model

  2015cites this paper
• Cell Therapy in Cardiac Diseases

  2015cites this paper
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  2015cites this paper
• Engineered Human Cardiac Tissue from Muscle Derived Stem Cells

  2015cites this paper
• Novel tissue engineering strategies based on the combination of polymeric devices and adult stem cells for cardiac repair

  2015cites this paper
• Percutaneous Cell Therapy for Acute and Chronic Cardiac Disease

  2014cites this paper
• Three-dimensional rotational angiography fused with multimodal imaging modalities for targeted endomyocardial injections in the ischaemic heart.

  2014cites this paper
• Cell-based Therapies for Cardiovascular Repair: How small things matter

  2014cites this paper
• Current Status and Perspectives in Stem Cell Therapy for Heart.

  2014cites this paper
• Cell therapy for cardiac repair – bench to bedside and back

  2014cites this paper
• Myocyte renewal and therapeutic myocardial regeneration using various progenitor cells

  2014cites this paper
• Cell Therapies in Cardiology

  2014cites this paper
• Intramyocardial Bone Marrow Cell Injection : Clinical and Functional Effects in Ischemic Heart Disease

  2014cites this paper
• Advanced cell-based cardiac repair: How to mend a broken heart

  2014influential citation
• Cardiac stem cell therapy: checkered past, promising future?

  2014cites this paper
• Tissue-Specific Progenitor and Stem Cells Concise Review : Skeletal Muscle Stem Cells and Cardiac Lineage : Potential for Heart Repair

  2014cites this paper
• Moving Beyond Surrogate Endpoints in Cell Therapy Trials for Heart Disease

  2014cites this paper
• Current outlook of cardiac stem cell therapy towards a clinical application

  2013cites this paper
• Cardiac Cell Therapy for Ischemic Heart Disease

  2013cites this paper
• Stammzellen in der Kardiologie: Mythos oder Realität?

  2013cites this paper
• Cardiac Regeneration with Stem Cells

  2013cites this paper
• Estudio aleatorizado de la terapia celular en el infarto agudo de miocardio : análisis de los efectos proliferativos de la terapia celular sobre la proliferación intimal y la aterosclerosis coronaria

  2013cites this paper
• Regenerative Medicine and Cell Therapy

  2013cites this paper
• Regenerative strategies for preserving and restoring cardiac function.

  2013cites this paper
• The Effects of Age, Disease State, and Granulocyte Colony-Stimulating Factor on Progenitor Cell Count and Function in Patients Undergoing Cell Therapy for Cardiac Disease

  2013cites this paper
• Stem Cell-Based Therapy for Ischemic Heart Disease

  2013cites this paper
• Stem Cell Therapy: Promising Treatment in Heart Failure?

  2013cites this paper
• Cellular cardiomyoplasty: its past, present, and future.

  2013cites this paper
• Do we have a future with transcatheter adventitial delivery of stem cells?

  2013cites this paper
• Autotransplantation of mesenchymal stromal cells from bone-marrow to heart in patients with severe stable coronary artery disease and refractory angina--final 3-year follow-up.

  2013cites this paper
• Impact of Hepatocyte Growth Factor on Skeletal Myoblast Transplantation Late After Myocardial Infarction

  2013cites this paper
• Human Cardiospheres as a Source of Multipotent Stem and Progenitor Cells

  2013cites this paper
• Intramyocardial autologous cell engraftment in patients with ischaemic heart failure: a meta-analysis of randomised controlled trials.

  2013influential citation
• Cell Therapy for Heart Failure: A Comprehensive Overview of Experimental and Clinical Studies, Current Challenges, and Future Directions

  2013cites this paper
• Chronic Heart Failure

  2013cites this paper
• Stem Cell Therapy for Ischemic Heart Disease

  2013cites this paper
• Rationale and design of the first randomized, double-blind, placebo-controlled trial of intramyocardial injection of autologous bone-marrow derived Mesenchymal Stromal Cells in chronic ischemic Heart Failure (MSC-HF Trial).

  2012cites this paper
• Genetic engineering of somatic cells to study and improve cardiac function.

  2012cites this paper
• THE SYSTEMIC STEM CELL RESPONSE TO CARDIAC PRESSURE OVERLOAD

  2012cites this paper