Surgical stress induces a shift in the type-1/type-2 T-helper cell balance, suggesting down-regulation of cell-mediated and up-regulation of antibody-mediated immunity commensurate to the trauma.

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Surgery

• Publication date

  1996-03-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/S0039-6060(96)80118-8PMID 8619187
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• CD30 (Ki-1) molecule: a new cytokine receptor of the tumor necrosis factor receptor superfamily as a tool for diagnosis and immunotherapy.

  1995cited by this paper
• Preferential expression of CD30 by human CD4+ T cells producing Th2‐type cytokines

  1995cited by this paper
• General Stress Response to Conventional and Laparoscopic Cholecystectomy

  1995cited by this paper
• Elective Laparoscopic Cholecystectomy Nearly Abolishes the Postoperative Hepatic Catabolic Stress Response

  1995cited by this paper
• The syntax of immune-neuroendocrine communication.

  1994cited by this paper
• Laparoscopic versus open cholecystectomy: Hospitalization, sick leave, analgesia and trauma responses

  1994cited by this paper
• Neuroendocrine-immune system interactions The immune-hypothalamo-pituitary-adrenal axis.

  1994cited by this paper
• Laparoscopic and minilaparotomy cholecystectomy: a randomized trial comparing postoperative pain and pulmonary function.

  1994cited by this paper
• Serum levels of soluble CD30 are elevated in the majority of untreated patients with Hodgkin's disease and correlate with clinical features and prognosis.

  1994cited by this paper
• Human Th1 and Th2 cells: functional properties, mechanisms of regulation, and role in disease.

  1994cited by this paper
• Physiological importance of dehydroepiandrosterone.

  1994cited by this paper
• CD30 defines a subset of activated human T cells that produce IFN-gamma and IL-5 and exhibit enhanced B cell helper activity.

  1994cited by this paper
• Lymphokine production by human T cells in disease states.

  1994cited by this paper
• Hormones, peripherally activated prohormones and regulation of the Th1/Th2 balance.

  1994cited by this paper
• Multihormonal regulation of dehydroepiandrosterone sulfotransferase messenger ribonucleic acid levels in adult rat liver.

  1994cited by this paper
• Cytokines and autoimmunity

  1994cited by this paper
• Flow cytometric determination of cytokines in activated murine T helper lymphocytes: Expression of interleukin‐10 in interferon‐γ and in interleukin‐4‐expressing cells

  1994cited by this paper
• Central nervous system-immune system interactions: psychoneuroendocrinology of stress and its immune consequences

  1994cited by this paper
• Exogenous growth hormone: Effects on the catabolic response to surgically produced acute stress and on postoperative immune function

  1993cited by this paper
• CD30 is a signal-transducing molecule that defines a subset of human activated CD45RO+ T cells.

  1993cited by this paper
• Inhibitors of protein tyrosine kinases and protein tyrosine phosphatases suppress IL-4-induced CD23 expression and release by human B lymphocytes.

  1993cited by this paper
• Cytokine regulation of T-cell function: potential for therapeutic intervention.

  1993cited by this paper
• Physiological and metabolic responses to open and laparoscopic cholecystectomy

  1992cited by this paper
• Metabolic and respiratory changes after cholecystectomy performed via laparotomy or laparoscopy.

  1992cited by this paper
• Induction of TH1 and TH2 responses: a key role for the 'natural' immune response?

  1992cited by this paper
• Traditional versus laparoscopic cholecystectomy.

  1991cited by this paper
• Dehydroepiandrosterone enhances IL2 production and cytotoxic effector function of human T cells.

  1991cited by this paper
• Conventional Versus laparoscopic cholecystectomy and the randomized controlled trial

  1991cited by this paper
• Cytokines as modulators of the hypothalamus-pituitary-adrenal axis.

  1991cited by this paper
• Changes in leukocyte subpopulations following total hip replacement surgery. Effects of high doses of corticosteroids.

  1991cited by this paper
• Coelioscopic Cholecystectomy: Preliminary Report of 36 Cases

  1990cited by this paper
• Qualitative and quantitative changes in platelets after coronary-artery bypass surgery may help identify thrombotic complications and infections

  1989cited by this paper
• Depressed interferon gamma production and monocyte HLA-DR expression after severe injury.

  1988cited by this paper
• Total intravenous anaesthesia with propofol and alfentanil by computer‐assisted infusion

  1988cited by this paper
• Human recombinant interleukin 4 induces Fc epsilon receptors (CD23) on normal human B lymphocytes

  1987cited by this paper
• Textbook of surgery: The biological basis of modern surgical practice

  1986cited by this paper
• All human monocytes have the capability of expressing HLA-DQ and HLA-DP molecules upon stimulation with interferon-gamma.

  1986cited by this paper
• Interferon-activated genes

  1986cited by this paper
• Experimental Evidence for a Vagally Mediated and Cholecystokinin‐independent Enteropancreatic Reflex

  1985cited by this paper
• The Natural History of Diagnosed Gallstone in Symptomatic and Asymptomatic Disease Patients

  1985cited by this paper
• The natural history of diagnosed gallstone disease in symptomatic and asymptomatic patients.

  1985cited by this paper
• Endocrine and metabolic changes during surgery: anaesthetic implications.

  1981cited by this paper
• Editorial: Growth hormone in surgical stress.

  1975cited by this paper
• Editorial: Growth hormone in surgical stress.

  1975cited by this paper
• New tables for multiple comparisons with a control.

  1964cited by this paper

• Robot-Assisted Colorectal Cancer Surgery Mitigates Early Postoperative Immunosuppression and Angiogenesis

  2025cites this paper
• Basophils activate splenic B cells and dendritic cells via IL-13 signaling in acute traumatic brain injury

  2025cites this paper
• The role of lidocaine in cancer progression and patient survival.

  2024cites this paper
• Pedal Reaction Forces and Electromyography Responses Indicate Eccentric Contractions During Motorized Cycling in a Rat Model of Incomplete Spinal Cord Injury

  2024cites this paper
• Perioperative Immune Checkpoint Blockade for Muscle-Invasive and Metastatic Bladder Cancer

  2024cites this paper
• Improving Geriatric Outcomes through Nutritional and Immunonutritional Strategies: focus on Surgical Setting by a Comprehensive Evidence Review.

  2024cites this paper
• Efficacy of Adjuvant Sublingual Immunotherapy After Septomeatoplasty

  2024cites this paper
• The Surgical Stress Response and Anesthesia: A Narrative Review

  2024cites this paper
• Occupational and Environmental Noise Exposure and Extra‐Auditory Effects on Humans: A Systematic Literature Review

  2023cites this paper
• Immune changes induced by periampullary adenocarcinoma are reversed after tumor resection and modulate the postoperative survival

  2023cites this paper
• Effect of anterior quadratus lumborum block with ropivacaine on the immune response after laparoscopic surgery in colon cancer: a substudy of a randomized clinical trial

  2023cites this paper
• Tumour excisional surgery, anaesthetic-analgesic techniques, and oncologic outcomes: a narrative review.

  2023cites this paper
• Immune Modulatory Effects of Nonsteroidal Anti-inflammatory Drugs in the Perioperative Period and Their Consequence on Postoperative Outcome

  2022cites this paper
• Effect of ulinastatin on the inflammatory response after video-assisted thoracic lobectomy in patients with lung cancer: a randomized controlled study

  2022cites this paper
• Spoken and Unspoken Matters Regarding the Use of Opioids in Cancer

  2022cites this paper
• Postoperative systemic inflammatory dysregulation and corticosteroids: a narrative review

  2022cites this paper
• Immune modulation after traumatic brain injury

  2022cites this paper
• The Immune Response to Major Gastrointestinal Cancer Surgery and Potential Implications for Adjuvant Immunotherapy.

  2022cites this paper
• Shift mechanisms of the immune response in open and laparoscopic surgeries

  2021cites this paper
• Comparative effects of on‐pump versus off‐pump coronary artery bypass grafting surgery on serum cytokine and chemokine levels

  2021cites this paper
• Perioperative Intravenous Lidocaine and Metastatic Cancer Recurrence - A Narrative Review

  2021cites this paper
• The Peripheral Immune System and Traumatic Brain Injury: Insight into the role of T-helper cells

  2021cites this paper
• Are postoperative NLR and PLR associated with the magnitude of surgery-related trauma in young and middle-aged patients with bicondylar tibial plateau fractures? A retrospective study

  2021cites this paper
• Microwave ablation induces Th1-type immune response with activation of ICOS pathway in early-stage breast cancer

  2021cites this paper
• Home enteral nutrition for postoperative elderly patients with esophageal cancer.

  2021cites this paper
• Systemic Inflammation after Uniport, Multiport, or Hybrid VATS Lobectomy for Lung Cancer

  2021cites this paper
• Is C-Reactive Protein (CRP) A Reliable Marker for Postoperative Complications in Gastrointestinal and Colorectal Surgery?

  2021cites this paper
• Effect of dexmedetomidine on CD4+ T cells and programmed cell death protein-1 in postoperative analgesia: a prospective, randomized, controlled study.

  2021cites this paper
• Early enteral feeding on esophageal cancer patients after esophageal resection and reconstruction.

  2020cites this paper
• Lessons from Hippocrates: Time to Change the Cancer Paradigm

  2020cites this paper
• A Systematic Review and Meta-Analysis of the Effects of Perioperative Immunonutrition in Gastrointestinal Cancer Patients

  2020cites this paper
• Ureaplasma parvum ventriculitis related to surgery and ventricular peritoneal drainage.

  2020cites this paper
• Etomidate is devoid of genotoxicty and mutagenicity in human lymphocytes and in the Salmonella typhimurium/microsomal activation test.

  2020cites this paper
• Surgical access trauma following minimally invasive thoracic surgery.

  2020cites this paper
• Effect of Enteral Immunonutrition on Immune, Inflammatory Markers and Nutritional Status in Gastric Cancer Patients Undergoing Gastrectomy: A Randomized Double-Blinded Controlled Trial

  2020cites this paper
• Proposing a convolutional neural network for stress assessment by means of derived heart rate from functional near infrared spectroscopy

  2020cites this paper
• Evaluation of Immunomodulatory Effect of Powdered Antrodia cinnamomea in Submerged Culture

  2020influential citation
• Operative Trauma and Blood Loss - Impact on Tumor Growth and Recurrence.

  2020cites this paper
• The inflammatory response to simulated day and night emergency alarm mobilisations

  2019cites this paper
• Can hospitalization be hazardous to your health? A nosocomial based stress model for hospitalization.

  2019cites this paper
• Immune reaction by cytoreductive prostatectomy.

  2019cites this paper
• Dynamic changes in human HLA‐DRA gene expression and Th cell subsets in sepsis: Indications of immunosuppression and associated outcomes

  2019cites this paper
• Monitoring the post surgery inflammatory host response

  2019cites this paper
• FREQUENCIES OF CD4 LYMPHOCYTES AND IL-4 IN PRE AND POSTOPERATIVE PERIODS AMONG LAPAROSCOPIC VERSUS CONVENTIONAL SURGERY IN IRAQI PATIENTS

  2019cites this paper
• A single centre, parallel group pilot study to investigate the effect of opioids on immunomarkers using gene expression profiling

  2019influential citation
• Can Hospitalization be Harmful for your Health? A Nosocomial Based Stress Model for Hospitalization

  2019cites this paper
• Accurate Stress Assessment based on functional Near Infrared Spectroscopy using Deep Learning Approach

  2019cites this paper
• Post‐operative complications in patients with a significant post‐operative decrease in γδT cells

  2019cites this paper
• Preoperative Immunonutrition for major abdominal cancer surgery

  2019cites this paper
• Pathophysiologic Implications of Cytokines Secretion during Liver Transplantation Surgery

  2018cites this paper
• Polymicrobial sepsis and non-specific immunization induce adaptive immunosuppression to a similar degree

  2018cites this paper
• The Use of C-Reactive Protein (CRP) as a Marker of the Surgical Stress in Gastrointestinal Surgery

  2018cites this paper
• The effect of anaesthetic technique during primary breast cancer surgery on neutrophil–lymphocyte ratio, platelet–lymphocyte ratio and return to intended oncological therapy

  2018cites this paper
• The perioperative dynamics of IL-7 following robot-assisted and open colorectal surgery

  2018cites this paper
• Changes in the Ratio of T Helper 1 to T Helper 2 Signature Cytokines in Patients Undergoing Living Donor Liver Transplantation Surgery: A Prospective Controlled Study.

  2018cites this paper
• The Potential for Cancer Immunotherapy in Targeting Surgery-Induced Natural Killer Cell Dysfunction

  2018cites this paper
• Peripheral inflammatory cytokines and immune balance in Generalised Anxiety Disorder: Case-controlled study.

  2017cites this paper
• Cytokine profile of NALT during acute stress and its possible effect on IgA secretion.

  2017cites this paper
• Intestinal inflammatory and redox responses to the perioperative administration of teduglutide in rats.

  2017cites this paper
• The Effect of Surgical Stress on Postoperative Tαβ and Tγδ Cell Distribution

  2017cites this paper
• MDSCs are induced after experimental blunt chest trauma and subsequently alter antigen-specific T cell responses

  2017cites this paper
• A model for lymphocyte activation in open versus laparoscopic surgery in colorectal cancer patients in enhanced recovery after surgery (ERAS) protocols

  2017cites this paper
• Immune Dysfunction Following Severe Polytrauma & Major Surgery: Exploring Mechanisms & Identifying Potential Therapies

  2017cites this paper
• Monocyte-Dependent Suppression of T-Cell Function in Postoperative Patients and Abdominal Sepsis

  2017cites this paper
• Determination of lymphocytes surface markers in patients with thermal burns and the influence of burn size on mononuclear cell subsets

  2017cites this paper
• Influence of the anti‐inflammatory cytokine interleukin‐4 on human joint capsule myofibroblasts

  2017cites this paper
• COMPARATIVE ANALYSIS OF IMMUNOLOGICAL PROFILES IN WOMEN UNDERGOING CONVENTIONAL AND SINGLE-PORT LAPAROSCOPIC CHOLECYSTECTOMY

  2016cites this paper
• Cytoreductive surgery for head and neck squamous cell carcinoma in the new age of immunotherapy.

  2016cites this paper
• EVALUATION OF MAIN INDEXES OF IMMUNE STATE IN THE PATIENTS WITH PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY WITH STENTING

  2016cites this paper
• The Effect of Transurethral Enucleation Resection of the Prostate for Benign Prostatic Hyperplasia on Immune and Stress Response

  2016cites this paper
• Longitudinal analysis of cytokine expression during neoadjuvant chemoradiotherapy and subsequent surgery in esophageal cancer patients.

  2016cites this paper
• Spontaneous negativation of serum hepatitis C virus RNA in type C chronic liver disese: A retrospective study

  2015cites this paper
• A propensity score-matching analysis comparing the oncological outcomes of laparoscopic and open surgery in patients with Stage I/II colon and upper rectal cancers

  2015cites this paper
• Optimisation of the Lister strain of vaccinia virus for use as an anticancer immunotherapeutic agent

  2015cites this paper
• Perioperative immunonutrition in patients undergoing liver transplantation: A randomized double‐blind trial

  2015cites this paper
• Intraoperative intravenous lidocaine exerts a protective effect on cell-mediated immunity in patients undergoing radical hysterectomy.

  2015cites this paper
• Role of Enteral Immunonutrition in Patients Undergoing Surgery for Gastric Cancer

  2015cites this paper
• Minimally invasive video-assisted versus conventional open thyroidectomy on immune response: a meta analysis.

  2015cites this paper
• Preoperative versus postoperative ultrasound-guided rectus sheath block for improving pain, sleep quality and cytokine levels of patients with open midline incisions undergoing transabdominal gynaecological operation: study protocol for a randomised controlled trial

  2015cites this paper
• Inflammatory Changes and Coagulopathy in Multiply Injured Patients

  2015cites this paper
• Upregulation of Immune Checkpoint Molecules, PD-1 and LAG-3, on CD4+ and CD8+ T Cells after Gastric Cancer Surgery

  2015cites this paper
• Potential therapeutic targets for sepsis in women

  2015cites this paper
• Effects of dexmedetomidine on patients undergoing radical gastrectomy.

  2015cites this paper
• Dynamic changes of circulating T-helper cell subsets following severe thoracic trauma.

  2015cites this paper
• Surgical Trauma and Immune Functional Changes Following Major Lung Resection

  2015cites this paper
• C-reactive protein after major abdominal surgery: biochemical and clinical aspects.

  2015cites this paper
• Effect of Propofol and Desflurane on Immune Cell Populations in Breast Cancer Patients: A Randomized Trial

  2015cites this paper
• The immune response to surgery and infection

  2014cites this paper
• Effects of Manual Lymph Drainage on the Activity of Sympathetic Nervous System, Anxiety, Pain, and Pressure Pain Threshold in Subjects with Psychological Stress

  2014cites this paper
• Preoperative immunonutrition decreases postoperative complications by modulating prostaglandin E2 production and T-cell differentiation in patients undergoing pancreatoduodenectomy.

  2014cites this paper
• Comparison of long-term oncologic outcomes of stage III colorectal cancer following laparoscopic versus open surgery

  2014cites this paper
• Nutritional Effect of Oral Supplement Enriched in ω-3 Fatty Acids, Arginine, RNA on Immune Response and Leukocyte–platelet Aggregate Formation in Patients Undergoing Cardiac Surgery

  2014cites this paper
• Effects of dexmedetomidine on the ratio of T helper 1 to T helper 2 cytokines in patients undergoing laparoscopic cholecystectomy.

  2014cites this paper
• Usefulness of testing for the prevalence of systemic inflammatory response syndrome (SIRS) in clinical practice

  2014cites this paper
• Identification of risk-factors for perioperative morbidity and mortality during different phases in the treatment of esophageal cancer patients

  2014cites this paper
• Preoperative assessment of the older surgical patient: honing in on geriatric syndromes

  2014cites this paper
• Spontaneous clearance of serum hepatitis C virus RNA during the clinical course of hepatocellular carcinoma in patients with chronic hepatitis C

  2014cites this paper
• Perioperative blood transfusion is associated with a gene transcription profile characteristic of immunosuppression: a prospective cohort study

  2014cites this paper
• Factores pronósticos del meningioma del paciente geriátrico

  2014cites this paper
• The plasma levels of the cytokines in opium-addicts and the effects of opium on the cytokines secretion by their lymphocytes.

  2013cites this paper